Personal information

Autophagy, mTOR, Insulin regulation, gene expression, post-transcriptional regulation, RNA binding protein, microRNA

Activities

Employment (1)

University of Texas Health Science Center at San Antonio: San Antonio, TX, US

2018-09-30 to present | Instructor/Research (Medicine)
Employment
Source: Self-asserted source
subramanya srikantan

Education and qualifications (1)

center for cellular and molecular biology: hyderabad, Telangana, IN

1999-08-02 to 2006-06-21 | Graduate Student
Qualification
Source: Self-asserted source
subramanya srikantan

Funding (1)

Tmem127, a novel Tissue specific regulator of glucose metabolism and lipogenesis

2019-07 to 2020-06 | Grant
Nathan Shock Center (San Antonio, Texas, US)
GRANT_NUMBER: 159167-23056-G2300
Source: Self-asserted source
subramanya srikantan

Works (46)

An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

Proceedings of the National Academy of Sciences
2020-07-14 | Journal article
Contributors: Sagnika Ghosh; Writoban Basu Ball; Travis R. Madaris; Subramanya Srikantan; Muniswamy Madesh; Vamsi K. Mootha; Vishal M. Gohil
Source: check_circle
Crossref

Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

Cell Reports
2019-03 | Journal article
Part of ISSN: 2211-1247
Source: Self-asserted source
subramanya srikantan

A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury

ACS Central Science
2019-01-23 | Journal article
Part of ISSN: 2374-7943
Part of ISSN: 2374-7951
Source: Self-asserted source
subramanya srikantan

The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex

Human Molecular Genetics
2018-05-15 | Journal article
Part of ISSN: 0964-6906
Part of ISSN: 1460-2083
Source: Self-asserted source
subramanya srikantan

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity

Nature Communications
2014-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
subramanya srikantan

Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs

Nucleic Acids Research
2014-01-01 | Journal article
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
subramanya srikantan

Copious urinary excretion of a male Syrian hamster (Mesocricetus auratus) salivary gland protein after its endocrine-like release upon β-adrenergic stimulation

General and Comparative Endocrinology
2013 | Journal article
DOI:

10.1016/j.ygcen.2013.02.016

Contributors: De, P.K.; Dubey, V.P.; Mohammad, M.P.; Rajan, W.D.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

In vivo and in vitro oncogenic effects of HIF2A mutations in pheochromocytomas and paragangliomas

Endocrine-Related Cancer
2013 | Journal article
DOI:

10.1530/ERC-13-0101

Contributors: Aguiar, R.C.T.; Dahia, P.L.M.; Deng, Y.; Kim, S.-W.; Li, Q.; Morales, N.P.; Pereira, M.A.A.; Qin, Y.; Srikantan, S.; Su, X. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

LincRNA-p21 Suppresses Target mRNA Translation

Molecular Cell
2013 | Journal article
DOI:

10.1016/j.molcel.2013.04.008

Contributors: Abdelmohsen, K.; Becker, K.; De, S.; Gorospe, M.; Huarte, M.; Martindale, J.; Srikantan, S.; Yang, X.; Yoon, J.-H.; Zhan, M.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

Nature Neuroscience
2013 | Journal article
DOI:

10.1038/nn.3479

Contributors: Brown, G.W.; Fox III, D.; Gorospe, M.; Guo, R.; Joshi, S.R.; Ko, M.S.H.; Lloyd, T.E.; Machamer, J.; Martindale, J.L.; Mohanty, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Functional interplay between RNA-binding protein HuR and microRNAs

Current Protein and Peptide Science
2012 | Journal article
DOI:

10.2174/138920312801619394

Contributors: Gorospe, M.; Srikantan, S.; Tominaga, K.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Growth Inhibition by miR-519 via Multiple p21-Inducing Pathways

Molecular and Cellular Biology
2012 | Journal article
DOI:

10.1128/MCB.00510-12

Contributors: Abdelmohsen, K.; Becker, K.G.; Gorospea, M.; Kang, M.-J.; Lal, A.; Martindale, J.L.; Maudsley, S.; Park, S.-S.; Srikantan, S.; Subramanian, M. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

HuR function in disease

Frontiers in Bioscience
2012 | Journal article
DOI:

10.2741/3921

Contributors: Gorospe, M.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

LincRNA-p21 Suppresses Target mRNA Translation

Molecular Cell
2012 | Journal article
DOI:

10.1016/j.molcel.2012.06.027

Contributors: Abdelmohsen, K.; Becker, K.G.; De, S.; Gorospe, M.; Huarte, M.; Martindale, J.L.; Srikantan, S.; Yang, X.; Yoon, J.-H.; Zhan, M.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

MS2-TRAP (MS2-tagged RNA affinity purification): Tagging RNA to identify associated miRNAs

Methods
2012 | Journal article
DOI:

10.1016/j.ymeth.2012.07.004

Contributors: Gorospe, M.; Srikantan, S.; Yoon, J.-H.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Regulation of senescence by microRNA biogenesis factors

Ageing Research Reviews
2012 | Journal article
DOI:

10.1016/j.arr.2012.01.003

Contributors: Abdelmohsen, K.; Gorospe, M.; Kang, M.-J.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

RNA-binding protein AUF1 represses Dicer expression

Nucleic Acids Research
2012 | Journal article
DOI:

10.1093/nar/gks930

Contributors: Abdelmohsen, K.; Gorospe, M.; Kang, M.-J.; Srikantan, S.; Tominaga-Yamanaka, K.; Yoon, J.-H.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Altered glycobiology of stem cells linked to age-related osteoarthritis

Aging
2011 | Journal article
Contributors: Gorospe, M.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Competitive regulation of nucleolin expression by HuR and miR-494

Molecular and Cellular Biology
2011 | Journal article
DOI:

10.1128/MCB.05955-11

Contributors: Abdelmohsen, K.; Gorospe, M.; Lee, E.K.; Martindale, J.L.; Srikantan, S.; Subaran, S.S.; Tominaga, K.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs

Nucleic Acids Research
2011 | Journal article
DOI:

10.1093/nar/gkr488

Contributors: Abdelmohsen, K.; Becker, K.G.; Carrier, F.; Gorospe, M.; Kang, M.-J.; Kim, M.M.; Lee, E.K.; Martindale, J.L.; Selimyan, R.; Srikantan, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation

EMBO Journal
2011 | Journal article
DOI:

10.1038/emboj.2011.24

Contributors: Abdelmohsen, K.; Becker, K.G.; Gorospe, M.; Kim, H.H.; Kim, M.M.; Lee, E.K.; Lehrmann, E.; Martindale, J.L.; Masuda, K.; Selimyan, R. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor γ expression

Molecular and Cellular Biology
2011 | Journal article
DOI:

10.1128/MCB.00894-10

Contributors: Abdelmohsen, K.; Egan, J.M.; Fried, S.K.; Gorospe, M.; Hutchison, E.R.; Kim, H.H.; Kim, M.M.; Kim, W.; Lee, E.K.; Lee, M.J. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Paradoxical microRNAs: Individual gene repressors, global translation enhancers

Cell Cycle
2011 | Journal article
DOI:

10.4161/cc.10.5.14825

Contributors: Abdelmohsen, K.; Becker, K.G.; Gorospe, M.; Marasa, B.S.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Senescence-associated microRNAs linked to tumorigenesis

Cell Cycle
2011 | Journal article
DOI:

10.4161/cc.10.19.17050

Contributors: Abdelmohsen, K.; Gorospe, M.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Translational control of TOP2A Influences doxorubicin efficacy

Molecular and Cellular Biology
2011 | Journal article
DOI:

10.1128/MCB.05639-11

Contributors: Abdelmohsen, K.; Chowdhury, D.; Gorospe, M.; Indig, F.E.; Kim, H.H.; Kim, M.M.; Kulshrestha, R.; Kuwano, Y.; Lee, E.K.; Marasa, B.S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

UneCLIPsing HuR Nuclear Function

Molecular Cell
2011 | Journal article
DOI:

10.1016/j.molcel.2011.07.016

Contributors: Gorospe, M.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of a female-specific lipocalin (FLP) expressed in the lacrimal glands of Syrian hamsters

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2010 | Journal article
DOI:

10.1107/S1744309110008237

Contributors: De, P.K.; Dubey, V.P.; Pal, B.; Pottabathini, S.; Sankaranarayanan, R.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

HnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies

Nature Structural and Molecular Biology
2010 | Journal article
DOI:

10.1038/nsmb.1815

Contributors: Abdelmohsen, K.; Gleichmann, M.; Gorospe, M.; Kim, H.H.; Kuwano, Y.; Lee, E.K.; Martindale, J.L.; Mattson, M.P.; Mughal, M.R.; Srikantan, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence

Aging
2010 | Journal article
Contributors: Abdelmohsen, K.; Gorospe, M.; Kim, M.M.; Lee, E.K.; Marasa, B.S.; Martindale, J.L.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

miR-375 inhibits differentiation of neurites by lowering HuD levels

Molecular and Cellular Biology
2010 | Journal article
DOI:

10.1128/MCB.00316-10

Contributors: Abdelmohsen, K.; Gorospe, M.; Hutchison, E.R.; Kim, M.M.; Kuwano, Y.; Lee, E.K.; Marasa, B.S.; Masuda, K.; Mattson, M.P.; Srikantan, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

miR-519 suppresses tumor growth by reducing HuR levels

Cell Cycle
2010 | Journal article
Contributors: Abdelmohsen, K.; Brennan, S.E.; De Cabo, R.; Gorospe, M.; Kim, M.M.; Mercken, E.M.; Srikantan, S.; Wilson, G.M.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Response to comment on "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs"

Science Signaling
2010 | Journal article
DOI:

10.1126/scisignal.3131lc2

Contributors: Abdelmohsen, K.; Gorospe, M.; Marasa, B.S.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Analysis of nitric oxide-stabilized mRNAs in human fibroblasts reveals HuR-dependent heme oxygenase 1 upregulation

Molecular and Cellular Biology
2009 | Journal article
DOI:

10.1128/MCB.01495-08

Contributors: Demple, B.; Gorospe, M.; Kuwano, Y.; Rabinovic, A.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

HuR recruits let-7/RISC to repress c-Myc expression

Genes and Development
2009 | Journal article
DOI:

10.1101/gad.1812509

Contributors: Eun, K.L.; Gorospe, M.; Hyeon, H.K.; Kuwano, Y.; Martindale, J.L.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Increased MKK4 abundance with replicative senescence Is linked to the joint reduction of multiple microRNAs

Science Signaling
2009 | Journal article
DOI:

10.1126/scisignal.2000442

Contributors: Abdelmohsen, K.; Gorospe, M.; Kuwano, Y.; Marasa, B.S.; Martindale, J.L.; Masuda, K.; Rinker-Schaeffer, C.W.; Srikantan, S.; Yang, X.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA

Nucleic Acids Research
2009 | Journal article
DOI:

10.1093/nar/gkp123

Contributors: Abdelmohsen, K.; Alaminos, M.; Berdasco, M.; Esteller, M.; Fraga, M.F.; Gorospe, M.; Jacinto, F.V.; López De Silanes, I.; Srikantan, S.; Taniguchi, H. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Ubiquitin-mediated proteolysis of HuR by heat shock

EMBO Journal
2009 | Journal article
DOI:

10.1038/emboj.2009.67

Contributors: Abdelmohsen, K.; Becker, K.G.; De Cabo, R.; Galban, S.; Gorospe, M.; Kamara, D.; Kim, H.H.; Kuwano, Y.; Lal, A.; Srikantan, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

Proceedings of the National Academy of Sciences of the United States of America
2008 | Journal article
DOI:

10.1073/pnas.0809376106

Contributors: Abdelmohsen, K.; Gorospe, M.; Kuwano, Y.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Nuclear HuR accumulation through phosphorylation by Cdk1

Genes and Development
2008 | Journal article
DOI:

10.1101/gad.1645808

Contributors: Abdelmohsen, K.; Blethrow, J.; Galban, S.; Gorospe, M.; Hyeon, H.K.; Lal, A.; Martindale, J.L.; Pullmann Jr., R.; Shokat, K.M.; Srikantan, S. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

p16INK4a translation suppressed by miR-24

PLoS ONE
2008 | Journal article
DOI:

10.1371/journal.pone.0001864

Contributors: Abdelmohsen, K.; Ahmed, F.; Dykxhoorn, D.; Gorospe, M.; Kim, H.H.; Kuwano, Y.; Lal, A.; Lieberman, J.; Martindale, J.L.; Navarro, F. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype

Oncogene
2008 | Journal article
DOI:

10.1038/onc.2008.215

Contributors: Becker, K.G.; Corl, S.; Gartenhaus, R.B.; Gorospe, M.; Hagner, P.R.; Keene, J.D.; Levenson, A.S.; Mazan-Mamczarz, K.; Srikantan, S.; Wood, W.H.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR

Journal of Allergy and Clinical Immunology
2008 | Journal article
DOI:

10.1016/j.jaci.2007.12.1166

Contributors: Asaki, S.Y.; Atasoy, U.X.; Casolaro, V.; De Fanis, U.; Fan, J.; Fang, X.; Gorospe, M.; Huang, S.-K.; Srikantan, S.; Stellato, C. et al.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters

General and Comparative Endocrinology
2008 | Journal article
DOI:

10.1016/j.ygcen.2008.07.019

Contributors: De, P.K.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Estrogen and androgen repression of two female specific lacrimal lipocalins in hamster: Pituitary independent and sex hormone receptor mediated action

General and Comparative Endocrinology
2007 | Journal article
DOI:

10.1016/j.ygcen.2007.01.003

Contributors: De, P.K.; Paliwal, A.; Quintanar-Stephano, A.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Histological and biochemical characterization of von Ebner's glands in the Syrian hamster; comparison with rat von Ebner's glands

Biotechnic and Histochemistry
2006 | Journal article
DOI:

10.1080/10520290601065128

Contributors: De, P.K.; Hand, A.R.; Paliwal, A.; Redman, R.S.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

CDNA cloning and regulation of two sex-hormone-repressed hamster tear lipocalins having homology with odorant/pheromone-binding proteins

Biochimica et Biophysica Acta - Gene Structure and Expression
2005 | Journal article
DOI:

10.1016/j.bbaexp.2005.04.008

Contributors: De, P.K.; Parekh, V.; Srikantan, S.
Source: Self-asserted source
subramanya srikantan via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for PloS one. (1)