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Scopus Author ID: 55935152300

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Leiden University Medical Center: Leiden, NL

2018-08-01 to present | Post-doc (Cell and Chemical Biology)
Employment
Source: Self-asserted source
Robbert Q. Kim

Works (25)

Covalent Probes To Capture <i>Legionella pneumophila</i> Dup Effector Enzymes

Journal of the American Chemical Society
2024-10-02 | Journal article | Author
DOI: 10.1021/jacs.4c08168
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Contributors: Max S. Kloet; Rishov Mukhopadhyay; Rukmini Mukherjee; Mohit Misra; Minwoo Jeong; Cami M. P. Talavera Ormeño; Angeliki Moutsiopoulou; Rayman T. N. Tjokrodirijo; Peter van Veelen; Donghyuk Shin et al.
Source: Self-asserted source
Robbert Q. Kim

USP24 is an ISG15 cross-reactive deubiquitinase that mediates IFN-I production by de-ISGylating the RNA helicase MOV10

2024-09-06 | Preprint
DOI: 10.1101/2024.09.06.611391
Contributors: Rishov Mukhopadhyay; Simeon D. Draganov; Jimmy J. L. L. Akkermans; Marjolein Kikkert; Klaus-Peter Knobeloch; Günter Fritz; María Guzmán; Sonia Zuñiga; Robbert. Q. Kim; Benedikt M. Kessler et al.
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Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell

Journal of Medicinal Chemistry
2024-05-23 | Journal article
DOI: 10.1021/acs.jmedchem.3c02410
Contributors: Yuqing Jia; Merve Oyken; Robbert Q. Kim; Rayman T.N. Tjokrodirijo; Arnoud H. de Ru; Antonius P. A. Janssen; Stephan M. Hacker; Peter A. van Veelen; Paul P. Geurink; Aysegul Sapmaz
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RNF26 binds perinuclear vimentin filaments to integrate ER and endolysosomal responses to proteotoxic stress

The EMBO Journal
2023-09-18 | Journal article
DOI: 10.15252/embj.2022111252
Contributors: Tom Cremer; Lenard M Voortman; Erik Bos; Marlieke LM Jongsma; Laurens R ter Haar; Jimmy JLL Akkermans; Cami MP Talavera Ormeño; Ruud HM Wijdeven; Jelle de Vries; Robbert Q Kim et al.
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Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2

ACS Chemical Biology
2023-09-15 | Journal article
DOI: 10.1021/acschembio.3c00227
Contributors: Jin Gan; Jelle de Vries; Jimmy J. L. L. Akkermans; Yassene Mohammed; Rayman T. N. Tjokrodirijo; Arnoud H. de Ru; Robbert Q. Kim; David A. Vargas; Vito Pol; Rudi Fasan et al.
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Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells

Frontiers in Immunology
2023-05-16 | Journal article
DOI: 10.3389/fimmu.2023.1183914
Part of ISSN: 1664-3224
Contributors: Willemijn van der Wulp; Anna M. Gram; Boris Bleijlevens; Renate S. Hagedoorn; Can Araman; Robbert Q. Kim; Jan Wouter Drijfhout; Paul W. H. I. Parren; Richard G. Hibbert; Rob C. Hoeben et al.
Source: Self-asserted source
Robbert Q. Kim

Technologies for Direct Detection of Covalent Protein–Drug Adducts

Pharmaceuticals
2023-04-05 | Journal article
DOI: 10.3390/ph16040547
Contributors: Elma Mons; Robbert Q. Kim; Monique P. C. Mulder
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Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes

Nature Communications
2023-03-25 | Journal article
DOI: 10.1038/s41467-023-37363-6
Contributors: Bianca D. M. van Tol; Bjorn R. van Doodewaerd; Guinevere S. M. Lageveen-Kammeijer; Bas C. Jansen; Cami M. P. Talavera Ormeño; Paul J. M. Hekking; Aysegul Sapmaz; Robbert Q. Kim; Angeliki Moutsiopoulou; David Komander et al.
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Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins

Journal of the American Chemical Society
2022-11-16 | Journal article
DOI: 10.1021/jacs.2c06249
Contributors: Jim Voorneveld; Max S. Kloet; Sven Wijngaarden; Robbert Q. Kim; Angeliki Moutsiopoulou; Marnix Verdegaal; Mohit Misra; Ivan Đikić; Gijsbert A. van der Marel; Herman S. Overkleeft et al.
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Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput

Journal of Medicinal Chemistry
2022-10-13 | Journal article
DOI: 10.1021/acs.jmedchem.2c01113
Contributors: Yuqing Jia; Robbert Q. Kim; Raymond Kooij; Huib Ovaa; Aysegul Sapmaz; Paul P. Geurink
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Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification

Proceedings of the National Academy of Sciences
2022-08-30 | Journal article
DOI: 10.1073/pnas.2209729119
DOI: 10.1101/2021.07.23.453408
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
EID:

2-s2.0-85113830056

Part of ISSN: 26928205
Contributors: Robbert Q. Kim
Source: Self-asserted source
Robbert Q. Kim
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A Comprehensive Guide for Assessing Covalent Inhibition in Enzymatic Assays Illustrated with Kinetic Simulations

Current Protocols
2022-06 | Journal article
DOI: 10.1002/cpz1.419
Contributors: Elma Mons; Sander Roet; Robbert Q. Kim; Monique P. C. Mulder
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S18-phosphorylation of USP7 regulates interaction with TCEAL4 that defines specific complexes and potentially distinct functions.

bioRxiv
2021 | Other
DOI: 10.1101/2021.07.07.451439
EID:

2-s2.0-85112724154

Part of ISSN: 26928205
Contributors: Querques, F.; Darling, S.; Cheetham-Wilkinson, I.; Kim, R.Q.; Hapangama, D.K.; Sixma, T.K.; Coulson, J.M.
Source: Self-asserted source
Robbert Q. Kim via Scopus - Elsevier

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining

Nature Communications
2021-11-12 | Journal article
DOI: 10.1038/s41467-021-26691-0
Contributors: Jenny Kaur Singh; Rebecca Smith; Magdalena B. Rother; Anton J. L. de Groot; Wouter W. Wiegant; Kees Vreeken; Ostiane D’Augustin; Robbert Q. Kim; Haibin Qian; Przemek M. Krawczyk et al.
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Exploring the Versatility of the Covalent Thiol–Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease

Journal of the American Chemical Society
2021-05-05 | Journal article
DOI: 10.1021/jacs.0c10513
Contributors: Elma Mons; Robbert Q. Kim; Bjorn R. van Doodewaerd; Peter A. van Veelen; Monique P. C. Mulder; Huib Ovaa
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Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.

Chemistry (Weinheim an der Bergstrasse, Germany)
2020-12-23 | Journal article
DOI: 10.1002/chem.202004590
PMID: 33075184
PMC: PMC7898697
Source: Self-asserted source
Robbert Q. Kim
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Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC

ChemBioChem
2020-06-16 | Journal article
DOI: 10.1002/cbic.202000230
Part of ISSN: 1439-4227
Part of ISSN: 1439-7633
Source: Self-asserted source
Robbert Q. Kim
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Quantitative analysis of USP activity in vitro.

Methods in enzymology
2019-02 | Journal article
DOI: 10.1016/bs.mie.2018.12.023
PMID: 30850056
Contributors: Dharadhar S; Kim RQ; Uckelmann M; Sixma TK
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

Nature communications
2019-01 | Journal article
DOI: 10.1038/s41467-018-08231-5
PMID: 30651545
PMC: PMC6335408
Contributors: Kim RQ; Geurink PP; Mulder MPC; Fish A; Ekkebus R; El Oualid F; van Dijk WJ; van Dalen D; Ovaa H; van Ingen H et al.
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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Regulation of USP7: A High Incidence of E3 Complexes.

Journal of molecular biology
2017-06 | Journal article
DOI: 10.1016/j.jmb.2017.05.028
PMID: 28591556
Contributors: Kim RQ; Sixma TK
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role.

Journal of structural biology
2016-05 | Journal article
DOI: 10.1016/j.jsb.2016.05.005
PMID: 27183903
Contributors: Kim RQ; van Dijk WJ; Sixma TK
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway.

Acta crystallographica. Section D, Biological crystallography
2013-12 | Journal article
DOI: 10.1107/s1399004713026655
PMID: 24419390
Contributors: Kim RQ; Offen WA; Davies GJ; Stubbs KA
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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The copper active site of CBM33 polysaccharide oxygenases.

Journal of the American Chemical Society
2013-04 | Journal article
DOI: 10.1021/ja402106e
PMID: 23540833
PMC: PMC3636778
Contributors: Hemsworth GR; Taylor EJ; Kim RQ; Gregory RC; Lewis SJ; Turkenburg JP; Parkin A; Davies GJ; Walton PH
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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Erratum: Direct evidence on the existence of [Mo<sub>132</sub>] keplerate-type species in aqueous solution (Inorganic Chemistry (2007) 46 (8469))

Inorganic Chemistry
2010 | Journal article
DOI: 10.1021/ic100859m
EID:

2-s2.0-77953555693

Part of ISSN: 00201669
Contributors: Roy, S.; Planken, K.L.; Kim, R.; Mandele, D.V.D.; Kegel, W.K.
Source: Self-asserted source
Robbert Q. Kim via Scopus - Elsevier

Direct evidence on the existence of [Mo132]Keplerate-type species in aqueous solution.

Inorganic chemistry
2007-09 | Journal article
DOI: 10.1021/ic701076s
PMID: 17850076
Contributors: Roy S; Planken KL; Kim R; Mandele Dv; Kegel WK
Source: Self-asserted source
Robbert Q. Kim via Europe PubMed Central
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