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Works (44)

Single‐cell profiling of MC1R‐inhibited melanocytes

Pigment Cell & Melanoma Research
2024-03 | Journal article
DOI: 10.1111/pcmr.13141
Contributors: H. Matthew Berns; Dawn E. Watkins‐Chow; Sizhu Lu; Pakavarin Louphrasitthiphol; Tongwu Zhang; Kevin M. Brown; Pedro Moura‐Alves; Colin R. Goding; William J. Pavan
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Distinct Genomic Landscape of Lung Adenocarcinoma from Household Use of Smoky Coal

American Journal of Respiratory and Critical Care Medicine
2023-09-15 | Journal article
DOI: 10.1164/rccm.202302-0340LE
Contributors: Tongwu Zhang; Phuc H. Hoang; Jason Y. Y. Wong; Kaiyun Yang; Kexin Chen; Maria Pik Wong; Roel C. H. Vermeulen; Yunchao Huang; Stephen J. Chanock; Nathaniel Rothman et al.
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Data from Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

2023-05-23 | Preprint
DOI: 10.1158/1055-9965.c.6660322.v1
Contributors: Louis-Jacques Ruel; Zhonglin Li; Nathalie Gaudreault; Cyndi Henry; Victoria Saavedra Armero; Dominique K. Boudreau; Tongwu Zhang; Maria Teresa Landi; Catherine Labbé; Christian Couture et al.
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Data from Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

2023-05-23 | Preprint
DOI: 10.1158/1055-9965.c.6660322
Contributors: Louis-Jacques Ruel; Zhonglin Li; Nathalie Gaudreault; Cyndi Henry; Victoria Saavedra Armero; Dominique K. Boudreau; Tongwu Zhang; Maria Teresa Landi; Catherine Labbé; Christian Couture et al.
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Supplementary Figure from Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

2023-05-23 | Preprint
DOI: 10.1158/1055-9965.23099374
Contributors: Louis-Jacques Ruel; Zhonglin Li; Nathalie Gaudreault; Cyndi Henry; Victoria Saavedra Armero; Dominique K. Boudreau; Tongwu Zhang; Maria Teresa Landi; Catherine Labbé; Christian Couture et al.
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Supplementary Figure from Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

2023-05-23 | Preprint
DOI: 10.1158/1055-9965.23099374.v1
Contributors: Louis-Jacques Ruel; Zhonglin Li; Nathalie Gaudreault; Cyndi Henry; Victoria Saavedra Armero; Dominique K. Boudreau; Tongwu Zhang; Maria Teresa Landi; Catherine Labbé; Christian Couture et al.
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Data from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.c.6532943
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Data from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.c.6532943.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 1 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489394
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 1 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489394.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 2 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489391
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 2 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489391.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 3 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489385
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 3 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489385.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 4 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489382
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 4 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489382.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 5 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489379
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary fig 5 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489379.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary Legend 1 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489397
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Supplementary Legend 1 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489397.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Table S1-S5 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489376
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Table S1-S5 from Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22489376.v1
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition

2023-03-10 | Preprint
DOI: 10.1101/2023.03.10.532018
Contributors: H. Matthew Berns; Dawn E. Watkins-Chow; Sizhu Lu; Pakavarin Louphrasitthiphol; Tongwu Zhang; Kevin M. Brown; Pedro Moura-Alves; Colin R. Goding; William J. Pavan
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Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical Outcomes

Clinical Cancer Research
2023-01-04 | Journal article
DOI: 10.1158/1078-0432.CCR-22-1865
Contributors: Jiwei Bai; Jianxin Shi; Yazhuo Zhang; Chuzhong Li; Yujia Xiong; Hela Koka; Difei Wang; Tongwu Zhang; Lei Song; Wen Luo et al.
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Tumor Mutational Burden by Whole-Genome Sequencing in Resected NSCLC of Never Smokers

Cancer Epidemiology, Biomarkers & Prevention
2022-12-05 | Journal article
DOI: 10.1158/1055-9965.EPI-22-0630
Contributors: Louis-Jacques Ruel; Zhonglin Li; Nathalie Gaudreault; Cyndi Henry; Victoria Saavedra Armero; Dominique K. Boudreau; Tongwu Zhang; Maria Teresa Landi; Catherine Labbé; Christian Couture et al.
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Time to first cigarette and its impact on lung tumorigenesis

2022-11-08 | Preprint
DOI: 10.1101/2022.11.07.515434
Contributors: Tongwu Zhang; Jian Sang; Neil Caporaso; Fangyi Gu; Amy Hutchinson; Dario Consonni; Angela C. Pesatori; Robert Homer; Stephen Chanock; Maria Teresa Landi
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DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype

JCI Insight
2022-10-10 | Journal article
DOI: 10.1172/jci.insight.156577
Contributors: Adriana Sanna; Bengt Phung; Shamik Mitra; Martin Lauss; Jiyeon Choi; Tongwu Zhang; Ching-Ni Njauw; Eugenia Cordero; Katja Harbst; Frida Rosengren et al.
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Integrated Analysis of Coexpression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma

Journal of Investigative Dermatology
2022-09 | Journal article
DOI: 10.1016/j.jid.2022.01.029
Contributors: Sally Yepes; Margaret A. Tucker; Hela Koka; Yanzi Xiao; Tongwu Zhang; Kristine Jones; Aurelie Vogt; Laurie Burdette; Wen Luo; Bin Zhu et al.
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Germline-somatic JAK2 interactions are associated with clonal expansion in myelofibrosis

Nature Communications
2022-09-08 | Journal article
DOI: 10.1038/s41467-022-32986-7
Contributors: Derek W. Brown; Weiyin Zhou; Youjin Wang; Kristine Jones; Wen Luo; Casey Dagnall; Kedest Teshome; Alyssa Klein; Tongwu Zhang; Shu-Hong Lin et al.
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ezQTL: A Web Platform for Interactive Visualization and Colocalization of QTLs and GWAS Loci

Genomics, Proteomics & Bioinformatics
2022-06-01 | Journal article
DOI: 10.1016/j.gpb.2022.05.004
Contributors: Tongwu Zhang; Alyssa Klein; Jian Sang; Jiyeon Choi; Kevin M. Brown
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ezQTL: A Web Platform for Interactive Visualization and Colocalization of Quantitative Trait Loci and GWAS

2022-03-09 | Preprint
DOI: 10.1101/2022.03.08.483491
Contributors: Tongwu Zhang; Alyssa Klein; Jian Sang; Jiyeon Choi; Kevin M Brown
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Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA

Nature
2022-02-17 | Journal article
DOI: 10.1038/s41586-022-04398-6
Contributors: Erik N. Bergstrom; Jens Luebeck; Mia Petljak; Azhar Khandekar; Mark Barnes; Tongwu Zhang; Christopher D. Steele; Nischalan Pillay; Maria Teresa Landi; Vineet Bafna et al.
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Clinical Implications of Inter- and Intratumor Heterogeneity of Immune Cell Markers in Lung Cancer

JNCI: Journal of the National Cancer Institute
2022-02-07 | Journal article
DOI: 10.1093/jnci/djab157
Contributors: Wei Zhao; Bin Zhu; Amy Hutchinson; Angela Cecilia Pesatori; Dario Consonni; Neil E Caporaso; Tongwu Zhang; Difei Wang; Jianxin Shi; Maria Teresa Landi
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Comparison of somatic mutation landscapes in Chinese versus European breast cancer patients

Human Genetics and Genomics Advances
2021-12 | Journal article
DOI: 10.1016/j.xhgg.2021.100076
Contributors: Bin Zhu; Lijin Joo; Tongwu Zhang; Hela Koka; DongHyuk Lee; Jianxin Shi; Priscilla Lee; Difei Wang; Feng Wang; Wing-cheong Chan et al.
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A large Canadian cohort provides insights into the genetic architecture of human hair colour

Communications Biology
2021-11-04 | Journal article
DOI: 10.1038/s42003-021-02764-0
Contributors: Frida Lona-Durazo; Marla Mendes; Rohit Thakur; Karen Funderburk; Tongwu Zhang; Michael A. Kovacs; Jiyeon Choi; Kevin M. Brown; Esteban J. Parra
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Genomic and evolutionary classification of lung cancer in never smokers

Nature Genetics
2021-09 | Journal article
DOI: 10.1038/s41588-021-00920-0
Contributors: Tongwu Zhang; Philippe Joubert; Naser Ansari-Pour; Wei Zhao; Phuc H. Hoang; Rachel Lokanga; Aaron L. Moye; Jennifer Rosenbaum; Abel Gonzalez-Perez; Francisco Martínez-Jiménez et al.
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The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors

Nature Communications
2021-09-13 | Journal article
DOI: 10.1038/s41467-021-25664-7
Contributors: Ali Khateb; Anagha Deshpande; Yongmei Feng; Darren Finlay; Joo Sang Lee; Ikrame Lazar; Bertrand Fabre; Yan Li; Yu Fujita; Tongwu Zhang et al.
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Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival

Nature Communications
2021-02-03 | Journal article
DOI: 10.1038/s41467-021-21026-5
Contributors: Jiwei Bai; Jianxin Shi; Chuzhong Li; Shuai Wang; Tongwu Zhang; Xing Hua; Bin Zhu; Hela Koka; Ho-Hsiang Wu; Lei Song et al.
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Regulation of eIF2α by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance

Journal of Investigative Dermatology
2020-12 | Journal article
DOI: 10.1016/j.jid.2020.04.008
Contributors: Emily Avitan-Hersh; Yongmei Feng; Avital Oknin Vaisman; Yamen Abu Ahmad; Yaniv Zohar; Tongwu Zhang; Joo Sang Lee; Ikrame Lazar; Saeed Sheikh Khalil; Yulia Feiler et al.
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The genomic and epigenomic evolutionary history of papillary renal cell carcinomas

Nature Communications
2020-06-18 | Journal article
DOI: 10.1038/s41467-020-16546-5
Contributors: Bin Zhu; Maria Luana Poeta; Manuela Costantini; Tongwu Zhang; Jianxin Shi; Steno Sentinelli; Wei Zhao; Vincenzo Pompeo; Maurizio Cardelli; Boian S. Alexandrov et al.
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Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

Nature Communications
2020-06-01 | Journal article
DOI: 10.1038/s41467-020-16590-1
Contributors: Jiyeon Choi; Tongwu Zhang; Andrew Vu; Julien Ablain; Matthew M. Makowski; Leandro M. Colli; Mai Xu; Rebecca C. Hennessey; Jinhu Yin; Harriet Rothschild et al.
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Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma

Nature Communications
2020-05-18 | Journal article
DOI: 10.1038/s41467-020-16295-5
Contributors: Xing Hua; Wei Zhao; Angela C. Pesatori; Dario Consonni; Neil E. Caporaso; Tongwu Zhang; Bin Zhu; Mingyi Wang; Kristine Jones; Belynda Hicks et al.
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Siah2 control of T-regulatory cells limits anti-tumor immunity

Nature Communications
2020-01-07 | Journal article
DOI: 10.1038/s41467-019-13826-7
Contributors: Marzia Scortegagna; Kathryn Hockemeyer; Igor Dolgalev; Joanna Poźniak; Florian Rambow; Yan Li; Yongmei Feng; Roberto Tinoco; Dennis C. Otero; Tongwu Zhang et al.
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Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1

Oncogene
2020-01-02 | Journal article
DOI: 10.1038/s41388-019-0971-7
Contributors: Michael Timaner; Ruslana Kotsofruk; Ziv Raviv; Ksenia Magidey; Dvir Shechter; Tal Kan; Alexander Nevelsky; Shahar Daniel; Elisabeth G. E. de Vries; Tongwu Zhang et al.
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Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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