Personal information

Other IDs

ResearcherID: K-2680-2017
Loop profile: 746757

Keywords

antibody-mediated rejection, genetic mismatch, glutathione S-transferase T1, liver transplantation,

Countries

Spain

Activities

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Employment (3)

Junta de Andalucia Consejería de Salud y Familias: Sevilla, Andalucía, ES

2014 to present | Senior researcher (Immunology)
Employment
Source: Self-asserted source
Isabel Aguilera

FISEVI: Sevilla, ES

2009-02-11 to 2014-02-10 | Researcher I3SNS (National Health System) (Immunology)
Employment
Source: Self-asserted source
Isabel Aguilera

FISEVI: Sevilla, ES

2003-02-10 to 2009-02-10 | Researcher Miguel Servet Program (Immunology)
Employment
Source: Self-asserted source
Isabel Aguilera

Education and qualifications (2)

University of Seville: Seville, Andalucia, ES

1992 to 1996 | PhD (Immunology)
Education
Source: Self-asserted source
Isabel Aguilera

Universidad de Sevilla Facultad de Biología: Sevilla, Andalucía, ES

1979-09-01 to 1984-07-01 | bachelor's degree (Genetics)
Education
Source: Self-asserted source
Isabel Aguilera

Professional activities (2)

Sociedad Española de Trasplantes: Madrid, ES

Membership
Source: Self-asserted source
Isabel Aguilera

Sociedad Española de Inmunología: Madrid, ES

Membership
Source: Self-asserted source
Isabel Aguilera

Funding (7)

PAPEL DE LOS ANTICUERPOS ESPECIFICOS DE DONANTE EN EL RECHAZO A LARGO PLAZO EN EL TRASPLANTE DE HÍGADO

2018-01 to 2020-12 | Grant
Ministerio de Economía y Competitividad (Instituto de Salud Carlos III, ES)
GRANT_NUMBER:

17/01403
Source: Self-asserted source
Isabel Aguilera

Relevancia de la respuesta inmune mediada por anticuerpos en el rechazo de los trasplantes de órganos y tejidos y en el desencadenamiento de la enfermedad de injerto contra huésped.

2014-06 to 2018-06 | Grant
Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía (´Sevilla, ES)
GRANT_NUMBER:

CTS-07846
Source: Self-asserted source
Isabel Aguilera

Hepatitis inmune de novo en el trasplante de hígado pediátrico

2012-01 to 2015-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

PI11/00857
Source: Self-asserted source
Isabel Aguilera

Bases moleculares del rechazo mediado por anticuerpos en los trasplantes de órganos sólidos

2008-01 to 2011-12 | Grant
Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía (´Sevilla, ES)
GRANT_NUMBER:

CTS 07/02886
Source: Self-asserted source
Isabel Aguilera

Base genética del rechazo mediado por anticuerpos específicos de donante en el trasplante de órganos sólidos. Papel de los anticuerpos anti-glutation S-transferasa T1

2008-01 to 2010-12 | Grant
Consejeria de Sanidad y Asuntos Sociales, Junta de Andalucía (Sevilla, ES)
GRANT_NUMBER:

PI-0332
Source: Self-asserted source
Isabel Aguilera

Mecanismos finos de actuación de los anticuerpos anti-glutation S-transferasa T1. Grados de patogenicidad en diversas situaciones posttrasplante

2006-01 to 2008-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

05/0733
Source: Self-asserted source
Isabel Aguilera

Incompatibilidad genética entre donante y receptor como causa de enfermedades autoinmunes de novo post-trasplante

2003-01 to 2005-12 | Grant
Ministerio de Sanidad, Servicios Sociales e Igualdad (Madrid, ES)
GRANT_NUMBER:

PI02/3072
Source: Self-asserted source
Isabel Aguilera

Works (43)

Glutathione S‐Transferase T1 Mismatch Is a Risk Factor for Chronic Ductopenic Rejection of Liver Allografts

Liver Transplantation
2020-10 | Journal article
DOI: 10.1002/lt.25815
Contributors: Jose Manuel Sousa; Lydia Barrera; Miguel Angel Gomez‐Bravo; Antonio Nuñez‐Roldan; Isabel Aguilera
Source: check_circle
Crossref

Identification of the cellular components involved in de novo immune hepatitis: a quantitative immunohistochemical analysis

Journal of Translational Medicine
2018-12 | Journal article
DOI: 10.1186/s12967-018-1440-8
Contributors: Elena Aguado-Domínguez; Lourdes Gómez; José Manuel Sousa; Miguel Ángel Gómez-Bravo; Antonio Núñez-Roldán; Isabel Aguilera
Source: check_circle
Crossref

Clinical association of anti-glutathione S-transferase T1 antibodies and de novo immune hepatitis after hematopoietic cell transplantation

Digestive and Liver Disease
2018-04 | Journal article
DOI: 10.1016/j.dld.2017.12.033
Contributors: Elena Aguado-Dominguez; Jose Manuel Sousa; Jose Antonio Perez-Simon; Isabel Aguilera
Source: check_circle
Crossref

De novo recipient-specific Glutathione S-transferase T1 antibody development after HLA-identical hematopoietic cell transplantation

Transplant Immunology
2018-02 | Journal article
DOI: 10.1016/j.trim.2017.12.002
Contributors: María José Martínez-Bravo; Berta Sánchez; María José Acevedo; José Antonio Pérez-Simón; Antonio Núñez-Roldán; Isabel Aguilera
Source: check_circle
Crossref

T-cell allorecognition of donor glutathione S.transferase T1 in plasma cell-rich rejection

World Journal of Hepatology
2017-09-28 | Journal article
DOI: DOI: 10.4254/wjh.v9.i27.1115
Source: Self-asserted source
Isabel Aguilera

IgG subclass profile among anti-Glutathione S-transferase T1 antibodies in post-transplant de novo immune hepatitis

Clinical Transplantation
2016 | Journal article
DOI: 10.1111/ctr.12675
WOSUID:

WOS:000372197100005
Contributors: Aguilera, Isabel; Jose Martinez-Bravo, Maria; Manuel Sousa, Jose; Jesus Pozo-Borrego, Antonio; Nunez-Roldan, Antonio
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Mismatch on Glutathione S-Transferase T1 Increases the Risk of Graft-versus-Host Disease and Mortality after Allogeneic Stem Cell Transplantation

Biology of Blood and Marrow Transplantation
2014 | Journal article
DOI: 10.1016/j.bbmt.2014.05.008
WOSUID:

WOS:000340986200015
Contributors: Jose Martinez-Bravo, Maria; Calderon-Cabrera, Cristina; Jose Marquez-Malaver, Francisco; Rodriguez, Nancy; Guijarro, Marta; Espigado, Idelfonso; Nunez-Roldan, Antonio; Antonio Perez-Simon, Jose; Aguilera, Isabel
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Comments on Anagnostis et al.: De novo autoimmune hepatitis associated with PTH(1-34) and PTH(1-84) administration for severe osteoporosis in a liver transplant patient

Osteoporosis International
2012 | Journal article
DOI: 10.1007/s00198-012-1926-9
WOSUID:

WOS:000307717700017
Contributors: Aguilera, I.; Nunez-Roldan, A.
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Choice of calcineurin inhibitor may influence the development of de novo immune hepatitis associated with anti-GSTT1 antibodies after liver transplantation

Clinical Transplantation
2011 | Journal article
DOI: 10.1111/j.1399-0012.2010.01221.x
WOSUID:

WOS:000289153400017
Contributors: Aguilera, Isabel; Sousa, Jose M.; Praena, Juan M.; Gomez-Bravo, Miguel A.; Nunez-Roldan, Antonio
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Complement Component 4d Immunohistochemistry in the Assessment of Liver Allograft Biopsy Samples: Applications and Pitfalls Reply

Liver Transplantation
2011 | Journal article
DOI: 10.1002/lt.22403
WOSUID:

WOS:000296701600018
Contributors: Aguilera, Isabel; Nunez-Roldan, Antonio
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Complement component 4d immunostaining in liver allografts of patients with de novo immune hepatitis

Liver Transplantation
2011-03 | Journal article
DOI: 10.1002/lt.22302
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Glutathione S-transferase T1 is a potential new target for the hepatic component of graft vs host disease after HSCT

Bone Marrow Transplantation
2010 | Journal article
DOI: 10.1038/bmt.2009.206
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Donor-specific antibodies against HLA, MICA, and GSTT1 in patients with allograft rejection and C4d deposition in renal biopsies

Transplantation
2009-01 | Journal article
DOI: 10.1097/TP.0b013e31818bd790
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Anti-glutathione S-transferase T1 antibody-mediated rejection in C4d-positive renal allograft recipients

Nephrology Dialysis and Transplantation
2008-02 | Journal article
DOI: 10.1093/ndt/gfm955
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Antibodies against glutathione S-transferase T1 in non-solid organ transplanted patients

Transfusion
2006 | Journal article
DOI: 10.1111/j.1537-2995.2006.00938.x
WOSUID:

WOS:000240147000009
Contributors: Wichmann, Ingeborg; Aguilera, Isabel; Sousa, Jose M.; Bernardos, Angel; Garcia Nunez, Emilio J.; Vigil, Eduardo; Magarino, Rosario; Magarino, Isabel; Torres, Antonia; Nunez-Roldan, Antonio
Source: Self-asserted source
Isabel Aguilera via ResearcherID

De novo autoimmune hepatitis following liver transplantation for primary biliary cirrhosis

Transplantation Proceedings
2006 | Journal article
DOI: 10.1016/j.transproceed.2006.03.071
WOSUID:

WOS:000238700500070
Contributors: Rodriguez-Diaz, Y; Reyes-Rodriguez, R; Dorta-Francisco, MC; Aguilera, I; Perera-Molinero, A; Moneva-Arce, E; Aviles-Ruiz, JF
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Alloimmune response against donor glutathione S-transferase T1 antigen in renal transplant recipients

American Journal of Kidney Diseases
2005 | Journal article
DOI: 10.1053/j.ajkd.2005.04.022
WOSUID:

WOS:000230926100020
Contributors: Aguilera, I; Wichmann, I; Gentil, MA; Gonzalez-Escribano, F; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Antibodies against the donor antigen glutathione S-transferase T1 after renal transplantation

Transplantation Proceedings
2005 | Journal article
DOI: 10.1016/j.transproceed.2005.02.045
WOSUID:

WOS:000228990100017
Contributors: Aguilera, I; Wichmann, I; Gentil, MA; Gonzalez-Escribano, F; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Glutathione S-transferase T1 genetic mismatch is a risk factor for de novo immune hepatitis in liver transplantation

Transplantation Proceedings
2005 | Journal article
DOI: 10.1016/j.transproceed.2005.10.042
WOSUID:

WOS:000234316400123
Contributors: Aguilera, I; Sousa, JM; Gavilan, F; Bernardos, A; Wichmann, I; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Lack of association of recipient MCP-1 gene promoter polymorphism with acute graft rejection after orthotopic liver transplantation

Transplantation Proceedings
2005 | Journal article
DOI: 10.1016/j.transproceed.2005.02.047
WOSUID:

WOS:000228990100033
Contributors: Franco-Lopez, E; Gonzalez-Escribano, MF; Aguilera, I; Pascasio, JM; Pareja, F; Bernardos, A; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Glutathione S-transferase T1 mismatch constitutes a risk factor for De Novo immune hepatitis after liver transplantation

Liver Transplantation
2004 | Journal article
DOI: 10.1002/lt.20209
WOSUID:

WOS:000223674400015
Contributors: Aguilera, I; Sousa, JM; Gavilan, F; Bernardos, A; Wichmann, I; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases

European Neurology
2002 | Journal article
DOI: 10.1159/000064955
WOSUID:

WOS:000177159900007
Contributors: Garcia-Lozano, JR; Mir, P; Alberca, R; Aguilera, I; Neciga, EG; Fernandez-Lopez, O; Cayuela, A; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Antibodies against glutathione S-transferase T1 (GSTT1) in patients with de novo immune hepatitis following liver transplantation

Clinical and Experimental Immunology
2001 | Journal article
DOI: 10.1046/j.1365-2249.2001.01682.x
WOSUID:

WOS:000175437200025
Contributors: Aguilera, I; Wichmann, I; Sousa, JM; Bernardos, A; Franco, E; Garcia-Lozano, JR; Nunez-Roldan, A
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Mitochondrial disease and stroke

Stroke
2001 | Journal article
DOI: 10.1161/hs1101.098328
WOSUID:

WOS:000172059800011
Contributors: Martinez-Fernandez, E; Gil-Peralta, A; Garcia-Lozano, R; Chinchon, I; Aguilera, I; Fernandez-Lopez, O; Arenas, J; Campos, Y; Bautista, J
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Mitochondrial DNA point mutation in the COI gene in a patient with McArdle's disease

Journal of the Neurological Sciences
2001 | Journal article
DOI: 10.1016/S0022-510X(01)00634-7
WOSUID:

WOS:000172431200011
Contributors: Aguilera, I; Garcia-Lozano, JR; Munoz, A; Arenas, J; Campos, Y; Chinchon, I; Roldan, AN; Bautista, J
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Molecular structure of eight human autoreactive monoclonal antibodies

Immunology
2001 | Journal article
DOI: 10.1046/j.1365-2567.2001.01159.x
WOSUID:

WOS:000168125600003
Contributors: Aguilera, I; Melero, J; Nunez-Roldan, A; Sanchez, B
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Lipomatosis, proximal myopathy, and the mitochondrial 8344 mutation. A lipid storage myopathy?

Muscle & Nerve
2000 | Journal article
DOI: 10.1002/(SICI)1097-4598(200004)23:4<538::AID-MUS12>3.0.CO;2-T
WOSUID:

WOS:000086003800012
Contributors: Munoz-Malaga, A; Bautista, J; Salazar, JA; Aguilera, I; Garcia, R; Chinchon, I; Segura, MD; Campos, Y; Arenas, J
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Identification of cation-independent mannose 6-phosphate receptor/insulin-like growth factor type-2 receptor as a novel target of autoantibodies

Immunology
1999 | Journal article
DOI: 10.1046/j.1365-2567.1999.00889.x
WOSUID:

WOS:000084434400024
Contributors: Tarrago, D; Aguilera, I; Melero, J; Wichmann, I; Nunez-Roldan, A; Sanchez, B
Source: Self-asserted source
Isabel Aguilera via ResearcherID

The rough deal protein is a new kinetochore component required for accurate chromosome segregation in Drosophila

Journal of Cell Science
1999 | Journal article
WOSUID:

WOS:000083819400017
Contributors: Scaerou, F; Aguilera, I; Saunders, R; Kane, N; Blottiere, L; Karess, R
Source: Self-asserted source
Isabel Aguilera via ResearcherID

The frequent expansion of a subpopulation of B cells that express RF-associated cross-reactive idiotypes: Evidence from analysis of a panel of autoreactive monoclonal antibodies

Scandinavian Journal of Immunology
1998 | Journal article
WOSUID:

WOS:000075271000007
Contributors: Melero, J; Aguilera, I; Mageed, RA; Jefferis, R; Tarrago, D; Nunez-Roldan, A; Sanchez, B
Source: Self-asserted source
Isabel Aguilera via ResearcherID

ASSOCIATION OF HLA-DR4-DW15 (DRB1-ASTERISK-0405) AND DR10 WITH RHEUMATOID-ARTHRITIS IN A SPANISH POPULATION

Arthritis and Rheumatism
1993 | Journal article
DOI: 10.1002/art.1780360611
WOSUID:

WOS:A1993LH46500011
Contributors: YELAMOS, J; GARCIALOZANO, JR; MORENO, I; AGUILERA, I; GONZALEZ, MF; GARCIA, A; NUNEZROLDAN, A; SANCHEZ, B
Source: Self-asserted source
Isabel Aguilera via ResearcherID

THE REGULATORY LIGHT CHAIN OF NONMUSCLE MYOSIN IS ENCODED BY SPAGHETTI-SQUASH, A GENE REQUIRED FOR CYTOKINESIS IN DROSOPHILA

Cell
1991 | Journal article
DOI: 10.1016/0092-8674(91)90013-O
WOSUID:

WOS:A1991FU89900010
Contributors: KARESS, RE; CHANG, XJ; EDWARDS, KA; KULKARNI, S; AGUILERA, I; KIEHART, DP
Source: Self-asserted source
Isabel Aguilera via ResearcherID

Anti-glutathione S-transferase T1 antibody-mediated rejection in C4d-positive renal allograft recipients.
Source: Self-asserted source
Isabel Aguilera

Antibodies against heterogeneous nuclear ribonucleoprotein K in patients with cardiac allograft vasculopathy.
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Choice of calcineurin inhibitor may influence the development of de novo immune hepatitis associated with anti-GSTT1 antibodies after liver transplantation.
Source: Self-asserted source
Isabel Aguilera

Clinical relevance of GSTT1 mismatch in solid organ and hematopoietic stem cell transplantation.
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 3)‎

Comments on Anagnostis et al.: De novo autoimmune hepatitis associated with PTH(1-34) and PTH(1-84) administration for severe osteoporosis in a liver transplant patient.
Source: Self-asserted source
Isabel Aguilera

Complement component 4d immunostaining in liver allografts of patients with de novo immune hepatitis.

Journal article
DOI: doi: 10.1002/lt.22302.
Source: Self-asserted source
Isabel Aguilera

De novo autoimmune hepatitis after interferon treatment in a liver transplant recipient with common variable immunodeficiency.
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 3)‎

Donor-specific antibodies against HLA, MICA, and GSTT1 in patients with allograft rejection and C4d deposition in renal biopsies.
Source: Self-asserted source
Isabel Aguilera

Glutathione S-transferase T1 is a potential new target for the hepatic component of graft vs host disease after HSCT.
Source: Self-asserted source
Isabel Aguilera

Influence of glutathione S-transferase T1 donor/recipient mismatch and anti-GSTT1 antibodies in hepatic graft-versus-host-disease.
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎

Positive association of anticytoskeletal endothelial cell antibodies and cardiac allograft rejection.
Source: Self-asserted source
Isabel Aguilera
grade
Preferred source (of 2)‎
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