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Drug Research and Development Center: Havana, CU

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Ramírez-Sánchez

Education and qualifications (1)

University of Havana: Havana, CU

Education
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Ramírez-Sánchez

Works (24)

JM-20 administration to animals with lesion of the nigrostriatal dopamine pathway induced by 6-hydroxydopamine, partially reverses motor damage and oxidative stress

2024-08-01 | Preprint
DOI: 10.1101/2024.07.30.605870
Contributors: Luis Arturo Fonseca-Fonseca; Laura Reina Taño Portuondo; Jeney Ramírez-Sánchez; Nancy Pavón Fuentes; Abel Mondelo Rodríguez; Víctor Diogenes Amaral da Silva; Silvia Lima Costa; Yanier Núñez-Figueredo
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A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine–dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke

2024-03-13 | Preprint
DOI: 10.1101/2024.03.08.584085
Contributors: Jeney Ramírez-Sánchez; André Rex; Sarah McCann; Daniel Schulze; Maylin Wong-Guerra; Luis A Fonseca-Fonseca; Enrique García-Alonso; Ailín Ramírez-Abreu; Ricardo Limonta; Monika Dopatka et al.
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JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats

NeuroToxicology
2021-12 | Journal article
DOI: 10.1016/j.neuro.2021.08.017
Contributors: Maylin Wong-Guerra; Yanay Montano-Peguero; Jeney Ramírez-Sánchez; Javier Jiménez-Martin; Luis Arturo Fonseca-Fonseca; Daniela Hernández-Enseñat; Yasmine Nonose; Odalys Valdés; Abel Mondelo-Rodriguez; Yaquelin Ortiz-Miranda et al.
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Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion

European Journal of Pharmacology
2021-03 | Journal article
DOI: 10.1016/j.ejphar.2021.174025
Part of ISSN: 0014-2999
Contributors: Jeney Ramírez-Sánchez; Maylin Wong-Guerra; Luis Arturo Fonseca-Fonseca; Elisa Nicoloso Simões Pires; Laura García-Pupo; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; René Delgado-Hernández; Christianne Salbego; Diogo O. Souza et al.
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JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties

NeuroToxicology
2021-01 | Journal article
DOI: 10.1016/j.neuro.2020.11.005
Part of ISSN: 0161-813X
Contributors: Luis Arturo Fonseca-Fonseca; Víctor Diogenes Amaral da Silva; Maylin Wong-Guerra; Jeney Ramírez-Sánchez; Alejandro Saúl Padrón Yaquis; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; Fillipe Mendes de Araújo; Rejane Conceição Santana; Tiago Fleming Outeiro et al.
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JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment

Neurological Research
2019-03-01 | Journal article
DOI: 10.1080/01616412.2019.1573285
Part of ISSN: 0161-6412
Contributors: Maylin Wong-Guerra; Javier Jiménez-Martin; Luis Arturo Fonseca-Fonseca; Jeney Ramírez-Sánchez; Yanay Montano-Peguero; Joao Batista Rocha; Fernanda D´Avila; Adriano M. de Assis; Diogo Onofre Souza; Gilberto L. Pardo-Andreu et al.
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JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease

Neuroscience Letters
2019-01 | Journal article
DOI: 10.1016/j.neulet.2018.10.008
Part of ISSN: 0304-3940
Contributors: Luis Arturo Fonseca-Fonseca; Maylin Wong-Guerra; Jeney Ramírez-Sánchez; Yanay Montano-Peguero; Alejandro Saúl Padrón Yaquis; Abel Mondelo Rodríguez; Víctor Diógenes Amaral da Silva; Silvia Lima Costa; Gilberto L. Pardo-Andreu; Yanier Núñez-Figueredo
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JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain

Molecular Neurobiology
2019-01-03 | Journal article
DOI: 10.1007/s12035-018-1087-8
Contributors: Jeney Ramírez-Sánchez; Elisa Nicoloso Simões Pires; André Meneghetti; Gisele Hansel; Yanier Nuñez-Figueredo; Gilberto L. Pardo-Andreu; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; René Delgado-Hernández; Christianne Salbego et al.
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Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia

Pharmacological Reports
2018-08 | Journal article
DOI: 10.1016/j.pharep.2018.02.013
Part of ISSN: 1734-1140
Contributors: Yanier Nuñez-Figueredo; Jeney Ramírez-Sánchez; Gilberto L. Pardo Andreu; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; Diogo O. Souza
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KM-34, a Novel Antioxidant Compound, Protects against 6-Hydroxydopamine-Induced Mitochondrial Damage and Neurotoxicity

Neurotoxicity Research
2018-01-02 | Journal article
DOI: 10.1007/s12640-017-9851-5
Part of ISSN: 1029-8428
Contributors: Luis Arturo Fonseca-Fonseca; Yanier Nuñez-Figueredo; Jeney Ramírez Sánchez; Maylin Wong Guerra; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; René Delgado Hernádez; Noelio J. Menezes-Filho; Teresa Cristina Silva Costa; Wagno Alcântara de Santana et al.
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Antioxidant and Neuroprotective Effects of KM-34, A Novel Synthetic Catechol, Against Oxidative Stress-Induced Neurotoxicity

Drug Research
2017-11-03 | Journal article
DOI: 10.1055/s-0043-121220
Part of ISSN: 2194-9379
Contributors: Yanier Nuñez-Figueredo; Jeney Ramirez-Sanchez; Yeniceis Issac; Estael Ochoa-Rodriguez; Yamila Verdecia-Reyes; Rene Delgado-Hernandez; Diogo Souza; Gilberto Andreu
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Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution

Brain, Behavior, and Immunity
2017-08 | Journal article
DOI: 10.1016/j.bbi.2017.04.002
Part of ISSN: 0889-1591
Contributors: Laura García-Pupo; Jeney Ramírez Sánchez; Dariusz Ratman; Claudina Pérez-Novo; Ken Declerck; Karolien De Bosscher; Marios Nektarios Markakis; Gerrit Beemster; Armando Zaldo; Yanier Nuñez Figueredo et al.
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Mitochondrial involvement in memory impairment induced by scopolamine in rats

Neurological Research
2017-04-11 | Journal article
DOI: 10.1080/01616412.2017.1312775
Part of ISSN: 0161-6412
Contributors: Maylin Wong-Guerra; Javier Jiménez-Martin; Gilberto L. Pardo-Andreu; Luis A. Fonseca-Fonseca; Diogo O. Souza; Adriano M. de Assis; Jeney Ramirez-Sanchez; Roberto Menéndez-Soto del Valle; Yanier Nuñez-Figueredo
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Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats

Journal of Pharmacy & Pharmacognosy Research
2016 | Journal article
Source: Self-asserted source
Ramírez-Sánchez

Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats

Journal of Pharmacy & Pharmacognosy Research
2016-01-01 | Journal article
DOI: 10.56499/jppres16.126_4.4.153
Contributors: Yanier Núñez Figueredo; Jeney Ramírez-Sanchez; Gisele Hansel; Gilberto L. Pardo-Andreu; Nelson Merino; Guillermo Aparicio; Rene Delgado-Hernández; Laura García-Pupo; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes et al.
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Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway

Neurochemistry International
2015-11 | Journal article
DOI: 10.1016/j.neuint.2015.09.003
Part of ISSN: 0197-0186
Contributors: Jeney Ramírez-Sánchez; Elisa Nicoloso Simões Pires; Yanier Nuñez-Figueredo; Gilberto L. Pardo-Andreu; Luis Arturo Fonseca-Fonseca; Alberto Ruiz-Reyes; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; René Delgado-Hernández; Diogo O. Souza et al.
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The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain

Neurochemistry International
2015-02 | Journal article
DOI: 10.1016/j.neuint.2015.01.006
Part of ISSN: 0197-0186
Contributors: Yanier Nuñez-Figueredo; Gilberto L. Pardo Andreu; Samanta Oliveira Loureiro; Marcelo Ganzella; Jeney Ramírez-Sánchez; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; René Delgado-Hernández; Diogo O. Souza
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A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo

Neuropharmacology
2014-10 | Journal article
DOI: 10.1016/j.neuropharm.2014.06.009
Part of ISSN: 0028-3908
Contributors: Yanier Nuñez-Figueredo; Jeney Ramírez-Sánchez; Gisele Hansel; Elisa Nicoloso Simões Pires; Nelson Merino; Odalys Valdes; René Delgado-Hernández; Alicia Lagarto Parra; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes et al.
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Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment

Brain Research Bulletin
2014-10 | Journal article
DOI: 10.1016/j.brainresbull.2014.10.001
Part of ISSN: 0361-9230
Contributors: Yanier Nuñez-Figueredo; Gilberto L. Pardo-Andreu; Jeney Ramírez-Sánchez; René Delgado-Hernández; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; Zeki Naal; Alexandre Pastoris Muller; Luis Valmor Portela; Diogo O. Souza
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JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro

European Journal of Pharmacology
2014-03 | Journal article
DOI: 10.1016/j.ejphar.2014.01.021
Part of ISSN: 0014-2999
Contributors: Yanier Nuñez-Figueredo; Jeney Ramírez-Sánchez; René Delgado-Hernández; Marlene Porto-Verdecia; Estael Ochoa-Rodríguez; Yamila Verdecia-Reyes; Javier Marin-Prida; Michael González-Durruthy; Sergio A. Uyemura; Fernando P. Rodrigues et al.
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Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule

Neurological Research
2013 | Journal article
DOI: 10.1179/1743132813y.0000000216
Part of ISSN: 0161-6412
Contributors: Yanier Nuñez Figueredo; Estael Ochoa Rodríguez; Yamila Verdecia Reyes; Carmen Carrillo Domínguez; Alicia Lagarto Parra; Jeney Ramirez Sánchez; René Delgado Hernández; Marlene Porto Verdecia; Gilberto L Pardo Andreu
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In vitro erythrocyte oxidative damage of Morinda citrifolia L (noni) leaves extract

Journal of Intercultural Ethnopharmacology
2013 | Journal article
DOI: 10.5455/jice.20130809114212
Part of ISSN: 2146-8397
Contributors: Alicia Lagarto; Jeney Ramirez; Yanier Nuez; Pham Hang; Trinh Diep
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Neuroprotective Action and Free Radical Scavenging Activity of Guttiferone-A, a Naturally Occurring Prenylated Benzophenone

Arzneimittelforschung
2012-10 | Journal article
DOI: 10.1055/s-0032-1327612
Part of ISSN: 0004-4172
Contributors: Y. Nuñez-Figueredo; L. García-Pupo; J. Ramírez-Sánchez; Y. Alcántara-Isaac; O. Cuesta-Rubio; R. Hernández; Z. Naal; C. Curti; G. Pardo-Andreu
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Multifunctional Molecule, JM-20, Reverses Aluminum Chloride-Induced Memory Impairment and Neuronal Damage in Rats

Other
DOI: 10.21203/rs.3.rs-163869/v1
Contributors: Maylin Wong-Guerra; Yanay Montano-Peguero; Jeney Ramírez-Sánchez; Javier Jiménez-Martin; Luis Arturo Fonseca-Fonseca; Daniela Hernández-Enseñat; Yasmine Nonose; Odalys Valdés; Abel Mondelo-Rodriguez; Yaquelin Ortiz-Miranda et al.
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