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Employment (1)

Massachusetts Institute of Technology: Cambridge, MA, US

2021-09-07 to present | Postdoctoral Fellow (Biology)
Employment
Source: Self-asserted source
Brandon Sit

Education and qualifications (2)

Harvard University: Boston, Massachusetts, US

2015-09 to 2021-05 | PhD in Biological and Biomedical Sciences (Microbiology and Immunobiology)
Education
Source: Self-asserted source
Brandon Sit

University of Toronto: Toronto, Ontario, CA

2011-09 to 2015-04 | HBSc. Immunology
Education
Source: Self-asserted source
Brandon Sit

Funding (5)

Investigating genes of unknown function required for Rickettsia parkeri infection

2022-08-15 to 2025-08-14 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12981070
GRANT_NUMBER: F32AI172121
Source: Self-asserted source
Brandon Sit via DimensionsWizard

Characterization of the nutrient transporter AfuABC in the human pathogen Vibrio cholerae

2018-04-01 to 2019-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8653666
GRANT_NUMBER: 665332
Source: Self-asserted source
Brandon Sit via DimensionsWizard

Characterization of the nutrient transporter AfuABC in the human pathogen Vibrio cholerae

2017-04-01 to 2018-03-31 | Grant
Natural Sciences and Engineering Research Council (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7715135
GRANT_NUMBER: 620548
Source: Self-asserted source
Brandon Sit via DimensionsWizard

Characterization of the nutrient transporter AfuABC in the human pathogen Vibrio cholerae

2016-04-01 to 2017-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/600400/Characterization-of-the-nutrient-transporter-AfuABC-in-the-human-pathogen-Vibrio-cholerae
GRANT_NUMBER: grant.600400
Source: Self-asserted source
Brandon Sit via DimensionsWizard

Metabolite-binding kinetics of the pathogenic bacterial periplasmic binding protein AfuA

2013-04-01 to 2014-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/537410/Metabolite-binding-kinetics-of-the-pathogenic-bacterial-periplasmic-binding-protein-AfuA
GRANT_NUMBER: grant.537410
Source: Self-asserted source
Brandon Sit via DimensionsWizard

Works (23)

A conserved interaction between the effector Sca4 and host clathrin suggests additional contributions for Sca4 during rickettsial infection

Infection and Immunity
2024-12-10 | Journal article
DOI: 10.1128/iai.00267-24
Contributors: Cassandra J. Vondrak; Brandon Sit; Chanakan Suwanbongkot; Kevin R. Macaluso; Rebecca L. Lamason; Guy H. Palmer
Source: check_circle
Crossref

Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module

Nature Communications
2024-08-23 | Journal article
DOI: 10.1038/s41467-024-51617-x
Contributors: Yunxue Guo; Kaihao Tang; Brandon Sit; Jiayu Gu; Ran Chen; Xinqi Shao; Shituan Lin; Zixian Huang; Zhaolong Nie; Jianzhong Lin et al.
Source: check_circle
Crossref

Pathogenic Rickettsia spp. as emerging models for bacterial biology

Journal of Bacteriology
2024-02-22 | Journal article
DOI: 10.1128/jb.00404-23
Contributors: Brandon Sit; Rebecca L. Lamason; George O'Toole
Source: check_circle
Crossref

Undecaprenyl phosphate translocases confer conditional microbial fitness

Nature
2023-01-26 | Journal article
DOI: 10.1038/s41586-022-05569-1
Contributors: Brandon Sit; Veerasak Srisuknimit; Emilio Bueno; Franz G. Zingl; Karthik Hullahalli; Felipe Cava; Matthew K. Waldor
Source: check_circle
Crossref

Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.

The Journal of experimental medicine
2022-11-22 | Journal article | Author
DOI: 10.1084/jem.20211938
PMID: 36413219
Contributors: Matute JD; jinzhi duan; Magdalena Flak; Paul Griebel; Jose Tascon Arcila; Shauni Doms; Thomas Hanley; Agne Antanaviciute; Jennifer Gundrum; Jessica Mark Welch et al.
Source: Self-asserted source
Brandon Sit

Proteomic analysis of the host–pathogen interface in experimental cholera

Nature Chemical Biology
2021-11-21 | Journal article
DOI: 10.1038/s41589-021-00894-4
Contributors: Abdelrahim Zoued; Hailong Zhang; Ting Zhang; Rachel T. Giorgio; Carole J. Kuehl; Bolutife Fakoya; Brandon Sit; Matthew K. Waldor
Source: check_circle
Crossref

Animal models for dissecting Vibrio cholerae intestinal pathogenesis and immunity.

Current opinion in microbiology
2021-10-22 | Journal article
DOI: 10.1016/j.mib.2021.09.007
PMID: 34695646
Source: Self-asserted source
Brandon Sit

Actinobacillus utilizes a binding protein–dependent ABC transporter to acquire the active form of vitamin B6

Journal of Biological Chemistry
2021-09 | Journal article
DOI: 10.1016/j.jbc.2021.101046
Contributors: Chuxi Pan; Alexandra Zimmer; Megha Shah; Minh Sang Huynh; Christine Chieh-Lin Lai; Brandon Sit; Yogesh Hooda; David M. Curran; Trevor F. Moraes
Source: check_circle
Crossref

Increased Listeria monocytogenes Dissemination and Altered Population Dynamics in Muc2-Deficient Mice.

Infection and immunity
2021-03-17 | Journal article
DOI: 10.1128/iai.00667-20
PMID: 33431704
PMC: PMC8090952
Source: Self-asserted source
Brandon Sit

BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

eLife
2021-02-16 | Journal article
DOI: 10.7554/eLife.60607
Contributors: Teresa del Peso Santos; Laura Alvarez; Brandon Sit; Oihane Irazoki; Jonathon Blake; Benjamin R Warner; Alyson R Warr; Anju Bala; Vladimir Benes; Matthew K Waldor et al.
Source: check_circle
Crossref

Dissecting serotype-specific contributions to live oral cholera vaccine efficacy

Proceedings of the National Academy of Sciences
2021-02-16 | Journal article
DOI: 10.1073/pnas.2018032118
Contributors: Brandon Sit; Bolutife Fakoya; Ting Zhang; Gabriel Billings; Matthew K. Waldor
Source: check_circle
Crossref

Type I interferon remodels lysosome function and modifies intestinal epithelial defense

Proceedings of the National Academy of Sciences
2020-11-24 | Journal article
DOI: 10.1073/pnas.2010723117
Contributors: Hailong Zhang; Abdelrahim Zoued; Xu Liu; Brandon Sit; Matthew K. Waldor
Source: check_circle
Crossref

Genetic Dissection of the Fermentative and Respiratory Contributions Supporting Vibrio cholerae Hypoxic Growth.

Journal of bacteriology
2020-11-19 | Journal article
DOI: 10.1128/jb.00243-20
PMID: 32631948
PMC: PMC7685561
Source: Self-asserted source
Brandon Sit

Transient Intestinal Colonization by a Live-Attenuated Oral Cholera Vaccine Induces Protective Immune Responses in Streptomycin-Treated Mice.

Journal of bacteriology
2020-11-19 | Journal article
DOI: 10.1128/jb.00232-20
PMID: 32540930
PMC: PMC7685556
Source: Self-asserted source
Brandon Sit

A Bacterial Pathogen Senses Host Mannose to Coordinate Virulence.

iScience
2019-09-25 | Journal article
DOI: 10.1016/j.isci.2019.09.028
PMID: 31605945
PMC: PMC6817725
Source: Self-asserted source
Brandon Sit

Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice

PLOS Neglected Tropical Diseases
2019-05-31 | Journal article
DOI: 10.1371/journal.pntd.0007417
Contributors: Brandon Sit; Mellisa Roskosky; Ting Zhang; Bolutife Fakoya; Aklima Akter; Rajib Biswas; Edward T. Ryan; Matthew K. Waldor
Source: check_circle
Crossref

CRISPR screen reveals that EHEC’s T3SS and Shiga Toxin rely on shared host factors for infection

mBio
2018 | Journal article
DOI: 10.1128/mBio.01003-18
EID:

2-s2.0-85048743651
Contributors: Pacheco, A.R.; Lazarus, J.E.; Sit, B.; Schmieder, S.; Lencer, W.I.; Blondel, C.J.; Doench, J.G.; Davis, B.M.; Waldor, M.K.
Source: Self-asserted source
Brandon Sit via Scopus - Elsevier

Anaerobic nitrate reduction divergently governs population expansion of the enteropathogen Vibrio cholerae

Nature Microbiology
2018-10-01 | Journal article
DOI: 10.1038/s41564-018-0253-0
Contributors: Emilio Bueno; Brandon Sit; Matthew K. Waldor; Felipe Cava
Source: check_circle
Crossref

A live vaccine rapidly protects against cholera in an infant rabbit model

Science Translational Medicine
2018-06-13 | Journal article
DOI: 10.1126/scitranslmed.aap8423
Contributors: Troy P. Hubbard; Gabriel Billings; Tobias Dörr; Brandon Sit; Alyson R. Warr; Carole J. Kuehl; Minsik Kim; Fernanda Delgado; John J. Mekalanos; Joseph A. Lewnard et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Type I interferon promotes cell-to-cell spread ofListeria monocytogenes

Cellular Microbiology
2016-10-10 | Journal article
DOI: 10.1111/cmi.12660
Contributors: Suzanne E. Osborne; Brandon Sit; Andrew Shaker; Elissa Currie; Joël M.J. Tan; Jorik van Rijn; Darren E. Higgins; John H. Brumell
Source: Self-asserted source
Brandon Sit via Crossref Metadata Search

Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen

PLOS Pathogens
2015-08 | Journal article
DOI: 10.1371/journal.ppat.1005107
Contributors: Brandon Sit; Shauna M. Crowley; Kirandeep Bhullar; Christine Chieh-Lin Lai; Calvin Tang; Yogesh Hooda; Charles Calmettes; Husain Khambati; Caixia Ma; John H. Brumell et al.
Source: Self-asserted source
Brandon Sit via Crossref Metadata Search

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

Radiotherapy and Oncology
2013-09 | Journal article
DOI: 10.1016/j.radonc.2013.06.005
Contributors: Dan Cojocari; Ravi N. Vellanki; Brandon Sit; David Uehling; Marianne Koritzinsky; Bradly G. Wouters
Source: Self-asserted source
Brandon Sit via Crossref Metadata Search

Long-term monitoring of crayfish populations in the Credit River at the Upper Canada College outdoor school

Freshwater Crayfish
2011-10 | Journal article
DOI: 10.5869/fc.2011.v18.83
Contributors: Premek Hamr; Brandon Sit
Source: Self-asserted source
Brandon Sit via Crossref Metadata Search

Peer review (8 reviews for 6 publications/grants)

Review activity for eLife (1)
Review activity for Heliyon. (1)
Review activity for Microbial pathogenesis. (2)
Review activity for New microbes and new infections. (1)
Review activity for PLoS neglected tropical diseases (1)
Review activity for STAR protocols. (2)
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