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ResearcherID: K-3726-2016
Loop profile: 70866
Scopus Author ID: 6603133707

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Germany

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Works (50)

Cell-based in vitro models for nasal permeability studies

Concepts and Models for Drug Permeability Studies
2024 | Book chapter
DOI: 10.1016/b978-0-443-15510-9.00012-8
Part of ISBN: 9780443155109
Contributors: Simone Ladel; Katharina Schindowski
Source: Self-asserted source
Katharina Schindowski

Differential Regulation of Neurotrophic Factors During Pathogenic Tau-Aggregation in a Tau Transgenic Mouse Model for Alzheimer’s Disease: A Protocol for Double-Labeling mRNA by In Situ Hybridization and Protein Epitopes by Immunohistochemistry

Methods in Molecular Biology
2024 | Book chapter | Author
DOI: 10.1007/978-1-0716-3629-9_20
Part of ISBN: 9781071636282
Part of ISBN: 9781071636299
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Katharina Schindowski
Source: Self-asserted source
Katharina Schindowski

Intranasal Nose-to-Brain Drug Delivery via the Olfactory Region in Mice: Two In-Depth Protocols for Region-Specific Intranasal Application of Antibodies and for Expression Analysis of Fc Receptors via In Situ Hybridization in the Nasal Mucosa

Methods in Molecular Biology
2024 | Book chapter
DOI: 10.1007/978-1-0716-3629-9_21
Part of ISBN: 9781071636282
Part of ISBN: 9781071636299
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Helena Herzog; Sara Glöckler; Johannes Flamm; Simone Ladel; Frank Maigler; Claudia Pitzer; Katharina Schindowski
Source: Self-asserted source
Katharina Schindowski

Characterization of a primary cellular airway model for inhalative drug delivery in comparison with the established permanent cell lines CaLu3 and RPMI 2650

In vitro models
2024-11-25 | Journal article | Author
DOI: 10.1007/s44164-024-00079-y
Part of ISSN: 2731-3441
Contributors: Janik Martin; Rebecca Rittersberger; Simon Treitler; Patrick Kopp; Anit Ibraimi; Gabriel Koslowski; Max Sickinger; Annabelle Dabbars; Katharina Schindowski
Source: Self-asserted source
Katharina Schindowski

Lactobacilli cell-free supernatants: Potential green and natural enhancers for nose-to-brain delivery of small hydrophilic molecules

Journal of Drug Delivery Science and Technology
2024-09 | Journal article | Author
DOI: 10.1016/j.jddst.2024.105929
Part of ISSN: 1773-2247
Contributors: Elisa Corazza; Janik Martin; BARBARA GIORDANI; Beatrice Vitali; martina rossi; Angela Abruzzo; Federica Bigucci; Teresa Cerchiara; Massimiliano Pio di Cagno; Barbara Luppi et al.
Source: Self-asserted source
Katharina Schindowski

Fc-Engineered Therapeutic Antibodies: Recent Advances and Future Directions

Pharmaceutics
2023-09 | Journal article | Author
DOI: 10.3390/pharmaceutics15102402
Contributors: Dalia T. Abdeldaim; Katharina Schindowski
Source: check_circle
Multidisciplinary Digital Publishing Institute

Nogo-A antibody delivery through the olfactory mucosa mitigates experimental autoimmune encephalomyelitis in the mouse CNS

Cell Death Discovery
2023-08-09 | Journal article
DOI: 10.1038/s41420-023-01588-7
Part of ISSN: 2058-7716
Contributors: Vincent Pernet; Sandrine Joly; Sebastian Spiegel; Ivo Meli; Sherif Idriss; Frank Maigler; Julius Baya Mdzomba; Anna K. Roenneke; Alessandra Franceschini; Ludovico Silvestri et al.
Source: Self-asserted source
Katharina Schindowski

A Novel MATLAB®-Algorithm-Based Video Analysis to Quantitatively Determine Solution Creeping in Intact Pharmaceutical Glass Vials

European Journal of Pharmaceutics and Biopharmaceutics
2022-09 | Journal article | Author
DOI: 10.1016/j.ejpb.2022.08.003
Part of ISSN: 0939-6411
Contributors: Daniel Molnar; Martina Röhm; Johannes Wutz; Ingrid Rivec; Annika Michel; Gina Klotz; Jürgen Hubbuch; Katharina Schindowski; Ingo Presser
Source: Self-asserted source
Katharina Schindowski

Hyaluronate Spreading Validates Mucin-Agarose Analogs as Test Systems to Replace Porcine Nasal Mucosa Explants – an Experimental and Theoretical Investigation

Colloids and Surfaces B: Biointerfaces
2022-07 | Journal article
DOI: 10.1016/j.colsurfb.2022.112689
Part of ISSN: 0927-7765
Source: Self-asserted source
Katharina Schindowski

Editorial: Intranasal Drug Delivery: Challenges and Opportunities

Frontiers in Pharmacology
2022-03-02 | Journal article
DOI: 10.3389/fphar.2022.868986
Part of ISSN: 1663-9812
Contributors: Ana Fortuna; Katharina Schindowski; Fabio Sonvico
Source: Self-asserted source
Katharina Schindowski

Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System

Frontiers in Pharmacology
2022-01-10 | Journal article
DOI: 10.3389/fphar.2021.789780
Part of ISSN: 1663-9812
Source: Self-asserted source
Katharina Schindowski

Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration

Antibodies
2021-11 | Journal article | Author
DOI: 10.3390/antib10040047
Contributors: Arghavan Soleimanizadeh; Heiko Dinter; Katharina Schindowski
Source: check_circle
Multidisciplinary Digital Publishing Institute

Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa

Pharmaceutics
2021-11 | Journal article | Author
DOI: 10.3390/pharmaceutics13111904
Contributors: Frank Maigler; Simone Ladel; Johannes Flamm; Stella Gänger; Barbara Kurpiers; Stefanie Kiderlen; Ronja Völk; Carmen Hamp; Sunniva Hartung; Sebastian Spiegel et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa

Frontiers in Pharmacology
2021-09-01 | Journal article
DOI: 10.3389/fphar.2021.732954
Part of ISSN: 1663-9812
Source: Self-asserted source
Katharina Schindowski

Impact of Glycosylation and Species Origin on the Uptake and Permeation of IgGs through the Nasal Airway Mucosa

Pharmaceutics
2020-10-23 | Journal article
DOI: 10.3390/pharmaceutics12111014
Part of ISSN: 1999-4923
Source: Self-asserted source
Katharina Schindowski
grade
Preferred source (of 2)‎

In vitro-Generation von Antikörpern mittels Phagen-Display

BIOspektrum
2020-05 | Journal article
DOI: 10.1007/s12268-020-1371-9
Part of ISSN: 0947-0867
Part of ISSN: 1868-6249
Source: Self-asserted source
Katharina Schindowski
grade
Preferred source (of 2)‎

Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Pharmaceutics
2019-08-01 | Journal article
DOI: 10.3390/pharmaceutics11080367
Part of ISSN: 1999-4923
Source: Self-asserted source
Katharina Schindowski
grade
Preferred source (of 2)‎

Efficient Construction and Effective Screening of Synthetic Domain Antibody Libraries

Methods and Protocols
2019-02 | Journal article | Author
DOI: 10.3390/mps2010017
Contributors: Arghavan Soleimanizadeh; Alissa Grässer; Heiko Dinter; Maximilian Hermes; Katharina Schindowski
Source: check_circle
Multidisciplinary Digital Publishing Institute

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Pharmaceutics
2018-08 | Journal article
DOI: 10.3390/pharmaceutics10030116
Source: check_circle
Multidisciplinary Digital Publishing Institute

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal <i>Lamina Propria</i>: Friend or Foe for Intranasal CNS Delivery?

Pharmaceutics
2018-07 | Journal article
DOI: 10.3390/pharmaceutics10030107
Source: check_circle
Multidisciplinary Digital Publishing Institute

A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery

International Journal of Pharmaceutics
2017 | Journal article
DOI: 10.1016/j.ijpharm.2017.09.027
EID:

2-s2.0-85029714379
Contributors: Röhm, M.; Carle, S.; Maigler, F.; Flamm, J.; Kramer, V.; Mavoungou, C.; Schmid, O.; Schindowski, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Regulation of neurotrophic factors during pathogenic tau-aggregation: A detailed protocol for double-labeling mRNA by in situ hybridization and protein epitopes by immunohistochemistry

Methods in Molecular Biology
2017 | Book
DOI: 10.1007/978-1-4939-6598-4_27
EID:

2-s2.0-85006409428
Contributors: Schindowski-Zimmermann, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Data of rational process optimization for the production of a full IgG and its Fab fragment from hybridoma cells

Data in Brief
2016 | Journal article
DOI: 10.1016/j.dib.2016.05.067
EID:

2-s2.0-84973596383
Contributors: Röhm, M.; Handl, A.; König, M.; Mavoungou, C.; Handrick, R.; Schindowski, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

First Steps to Develop and Validate a CFPD Model in Order to Support the Design of Nose-to-Brain Delivered Biopharmaceuticals

Pharmaceutical Research
2016 | Journal article
DOI: 10.1007/s11095-016-1875-7
EID:

2-s2.0-84958743989
Contributors: Engelhardt, L.; Röhm, M.; Mavoungou, C.; Schindowski, K.; Schafmeister, A.; Simon, U.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Nose-to-brain delivery of insulin for Alzheimer's disease

ADMET and DMPK
2015 | Journal article
DOI: 10.5599/admet.3.3.184
EID:

2-s2.0-85029716334
Contributors: Stützle, M.; Flamm, J.; Carle, S.; Schindowski, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Is abeta a sufficient biomarker for monitoring anti-abeta clinical studies? A critical review

Frontiers in Aging Neuroscience
2013 | Journal article
DOI: 10.3389/fnagi.2013.00025
EID:

2-s2.0-84883544430
Contributors: Moreth, J.; Mavoungou, C.; Schindowski, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?

Immunity and Ageing
2013 | Journal article
DOI: 10.1186/1742-4933-10-18
EID:

2-s2.0-84877254025
Contributors: Moreth, J.; Mavoungou, C.; Schindowski, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Loss of Medial Septum Cholinergic Neurons in THY-Tau22 Mouse Model: What links with TAU pathology?

Current Alzheimer Research
2011 | Journal article
DOI: 10.2174/156720511796717230
EID:

2-s2.0-79958183494
Contributors: Belarbi, K.; Burnouf, S.; Fernandez-Gomez, F.; Desmercières, J.; Troquier, L.; Brouillette, J.; Tsambou, L.; Grosjean, M.; Caillierez, R.; Demeyer, D. et al.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Regulation of GDF-15, a distant TGF-β superfamily member, in a mouse model of cerebral ischemia

Cell and Tissue Research
2011 | Journal article
DOI: 10.1007/s00441-010-1090-5
EID:

2-s2.0-79953844979
Contributors: Schindowski, K.; Von Bohlen Und Halbach, O.; Strelau, J.; Ridder, D.A.; Herrmann, O.; Schober, A.; Schwaninger, M.; Unsicker, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Early tau pathology involving the septo-hippocampal pathway in a tau transgenic model: Relevance to alzheimer's disease

Current Alzheimer Research
2009 | Journal article
DOI: 10.2174/156720509787602843
EID:

2-s2.0-64549147983
Contributors: Belarbi, K.; Schindowski, K.; Burnouf, S.; Caillierez, R.; Grosjean, M.-E.; Demeyer, D.; Hamdane, M.; Sergeant, N.; Blum, D.; Buée, L.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Expression of trkB and trkC receptors and their ligands brain-derived neurotrophic factor and neurotrophin-3 in the murine amygdala

Journal of Neuroscience Research
2008 | Journal article
DOI: 10.1002/jnr.21490
EID:

2-s2.0-38849198650
Contributors: Krause, S.; Schindowski, K.; Zechel, S.; Von Bohlen Und Halbach, O.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation

Genes, Brain and Behavior
2008 | Journal article
DOI: 10.1111/j.1601-183X.2007.00377.x
EID:

2-s2.0-37749043746
Contributors: Schindowski, K.; Belarbi, K.; Bretteville, A.; Ando, K.; Buée, L.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Neurotrophic factors in Alzheimer's disease: Role of axonal transport

Genes, Brain and Behavior
2008 | Journal article
DOI: 10.1111/j.1601-183X.2007.00378.x
EID:

2-s2.0-37849050242
Contributors: Schindowski, K.; Belarbi, K.; Buée, L.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice

American Journal of Pathology
2007 | Journal article
DOI: 10.2353/ajpath.2007.070345
EID:

2-s2.0-34548829896
Contributors: Leroy, K.; Bretteville, A.; Schindowski, K.; Gilissen, E.; Authelet, M.; De Decker, R.; Yilmaz, Z.; Buée, L.; Brion, J.-P.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Enhanced apoptosis, oxidative stress and mitochondrial dysfunction in lymphocytes as potential biomarkers for Alzheimer's disease

Journal of Neural Transmission, Supplementa
2007 | Book
DOI: 10.1007/978-3-211-73574-9-27
EID:

2-s2.0-38449101620
Contributors: Leuner, K.; Pantel, J.; Frey, C.; Schindowski, K.; Schulz, K.; Wegat, T.; Maurer, K.; Eckert, A.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Increased T-cell reactivity and elevated levels of CD8<sup>+</sup>memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: Implications for immunotherapy

NeuroMolecular Medicine
2007 | Journal article
DOI: 10.1007/s12017-007-8015-9
EID:

2-s2.0-38749120306
Contributors: Schindowski, K.; Eckert, A.; Peters, J.; Gorriz, C.; Schramm, U.; Weinandi, T.; Maurer, K.; Frölich, L.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

American Journal of Pathology
2006 | Journal article
DOI: 10.2353/ajpath.2006.060002
EID:

2-s2.0-33746652117
Contributors: Schindowski, K.; Bretteville, A.; Leroy, K.; Bégard, S.; Brion, J.-P.; Hamdane, M.; Buée, L.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Apoptosis of CD4<sup>+</sup> T and natural killer cells in Alzheimer's disease

Pharmacopsychiatry
2006 | Journal article
DOI: 10.1055/s-2006-954591
EID:

2-s2.0-33845411881
Contributors: Schindowski, K.; Peters, J.; Gorriz, C.; Schramm, U.; Weinandi, T.; Leutner, S.; Maurer, K.; Frölich, L.; Müller, W.E.; Eckert, A.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Enhanced ROS-generation in lymphocytes from Alzheimer's patients

Pharmacopsychiatry
2005 | Journal article
DOI: 10.1055/s-2005-916186
EID:

2-s2.0-29144447296
Contributors: Leutner, S.; Schindowski, K.; Frölich, L.; Maurer, K.; Kratzsch, T.; Eckert, A.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death

Journal of Cell Science
2005 | Journal article
DOI: 10.1242/jcs.01724
EID:

2-s2.0-17244366995
Contributors: Hamdane, M.; Bretteville, A.; Sambo, A.-V.; Schindowski, K.; Bégard, S.; Delacourte, A.; Bertrand, P.; Buée, L.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2

Experimental Neurology
2004 | Journal article
DOI: 10.1016/j.expneurol.2004.06.004
EID:

2-s2.0-4544267683
Contributors: Kiprianova, I.; Schindowski, K.; Von Bohlen Und Halbach, O.; Krause, S.; Dono, R.; Schwaninger, M.; Unsicker, K.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Effects of EGb 761® Ginkgo biloba extract on mitochondrial function and oxidative stress

Pharmacopsychiatry
2003 | Journal article
EID:

2-s2.0-0041324740
Contributors: Eckert, A.; Keil, U.; Kressmann, S.; Schindowski, K.; Leutner, S.; Leutz, S.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Impact of Aging: Sporadic, and Genetic Risk Factors on Vulnerability to Apoptosis in Alzheimer's Disease

NeuroMolecular Medicine
2003 | Journal article
DOI: 10.1385/NMM:4:3:161
EID:

2-s2.0-9144269665
Contributors: Schindowski, K.; Kratzsch, T.; Peters, J.; Steiner, B.; Leutner, S.; Touchet, N.; Maurer, K.; Czech, C.; Pradier, L.; Frölich, L. et al.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Age-related impairment of human T lymphocytes' activation: Specific differences between CD4<sup>+</sup>and CD8<sup>+</sup>subsets

Mechanisms of Ageing and Development
2002 | Journal article
DOI: 10.1016/S0047-6374(01)00396-7
EID:

2-s2.0-0036137043
Contributors: Schindowski, K.; Fröhlich, L.; Maurer, K.; Müller, W.E.; Eckert, A.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761)

Journal of Neurology
2001 | Journal article
EID:

2-s2.0-0034862318
Contributors: Schindowski, K.; Leutner, S.; Kressmann, S.; Eckert, A.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761).

Journal of neural transmission (Vienna, Austria : 1996)
2001 | Journal article
DOI: 10.1007/s007020170016
EID:

2-s2.0-0035226056
Contributors: Schindowski, K.; Leutner, S.; Kressmann, S.; Eckert, A.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice

Neurobiology of Disease
2001 | Journal article
DOI: 10.1006/nbdi.2000.0378
EID:

2-s2.0-0035029341
Contributors: Eckert, A.; Schindowski, K.; Leutner, S.; Luckhaus, C.; Touchet, N.; Czech, C.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Age-related changes of apoptotic cell death in human lymphocytes

Neurobiology of Aging
2000 | Journal article
DOI: 10.1016/S0197-4580(00)00171-8
EID:

2-s2.0-0034282322
Contributors: Schindowski, K.; Leutner, S.; Müller, W.E.; Eckert, A.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations

Neuroscience Letters
2000 | Journal article
DOI: 10.1016/S0304-3940(00)01449-X
EID:

2-s2.0-0034613438
Contributors: Leutner, S.; Czech, C.; Schindowski, K.; Touchet, N.; Eckert, A.; Müller, W.E.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system

Cancer Gene Therapy
1999 | Journal article
DOI: 10.1038/sj.cgt.7700021
EID:

2-s2.0-0033088239
Contributors: Pitzer, C.; Schindowski, K.; Pomer, S.; Wirth, T.; Zöller, M.
Source: Self-asserted source
Katharina Schindowski via Scopus - Elsevier

Peer review (3 reviews for 3 publications/grants)

Review activity for Lab animal. (1)
Review activity for Nature biotechnology. (1)
Review activity for The lancet. (1)
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