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EPFL - École Polytechnique Fédérale de Lausanne: Lausanne, CH

2013 to 2025 (School of Life Sciences, Core Facility, Biomolecular Screening Core Facility)
Employment
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ORCID Integration at EPFL

Works (29)

Aurora kinase B is required for growth and expansion of medulloblastoma cells in the tissue context

Neoplasia
2025-01 | Journal article
DOI: 10.1016/j.neo.2024.101078
Contributors: Alexandre Gries; Karthiga Santhana Kumar; Fabien Kuttler; Özgün Özalp; Veronica Akle; Hanqing Zhang; Michael A. Grotzer; Stephan C.F. Neuhauss; Amin Allalou; Martin Baumgartner
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Crossref

Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma

JCI Insight
2024-07-22 | Journal article
DOI: 10.1172/jci.insight.169647
Contributors: Santhoshkumar Sundaramoorthy; Daniele Filippo Colombo; Rajendran Sanalkumar; Liliane Broye; Katia Balmas Bourloud; Gaylor Boulay; Luisa Cironi; Ivan Stamenkovic; Raffaele Renella; Fabien Kuttler et al.
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Crossref

Fluorescent fatty acid conjugates for live cell imaging of peroxisomes

Nature Communications
2024-05-21 | Journal article
DOI: 10.1038/s41467-024-48679-2
Contributors: Daria Korotkova; Anya Borisyuk; Anthony Guihur; Manon Bardyn; Fabien Kuttler; Luc Reymond; Milena Schuhmacher; Triana Amen
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Crossref

Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma

Cancer Science
2023-09 | Journal article
DOI: 10.1111/cas.15878
Contributors: Irina L. Sinenko; Fabien Kuttler; Valentin Simeonov; Alexandre Moulin; Patrick Aouad; Christina Stathopoulos; Francis L. Munier; Adeline Berger; Paul J. Dyson
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Crossref

Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern

Current Research in Virological Science
2022 | Journal article | Author
DOI: 10.1016/j.crviro.2022.100019
Part of ISSN: 2666-478X
Contributors: Luca Murer; Romain Volle; Vardan Andriasyan; Anthony Petkidis; Alfonso Gomez; Liliane Yang; Nicole Meili; Maarit Suomalainen; Michael Bauer; Daniela Policarpo Sequeira et al.
Source: Self-asserted source
Fabien Kuttler

Corrigendum: High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

Journal of Lipid Research
2022-10 | Journal article
DOI: 10.1016/j.jlr.2022.100291
Part of ISSN: 0022-2275
Contributors: Vasco Campos; Benjamin Rappaz; Fabien Kuttler; Gerardo Turcatti; Olaia Naveiras
Source: Self-asserted source
Fabien Kuttler

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

Scientific Data
2022-10-08 | Journal article
DOI: 10.1038/s41597-022-01733-4
Contributors: Dominik Olszewski; Fanny Georgi; Luca Murer; Vardan Andriasyan; Fabien Kuttler; Anthony Petkidis; Robert Witte; Artur Yakimovich; Lucy Fischer; Alina Rozanova et al.
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Crossref

Identification of New Vulnerabilities in Conjunctival Melanoma Using Image-Based High Content Drug Screening

Cancers
2022-03 | Journal article | Author
DOI: 10.3390/cancers14061575
Contributors: Katya Nardou; Michael Nicolas; Fabien Kuttler; Katarina Cisarova; Elifnaz Celik; Mathieu Quinodoz; Nicolo Riggi; Olivier Michielin; Carlo Rivolta; Gerardo Turcatti et al.
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Arrayed multicycle drug screens identify broadly acting chemical inhibitors for repurposing against SARS-CoV-2

[]
2021-03-31 | Preprint
DOI: 10.1101/2021.03.30.437771
Source: Self-asserted source
Fabien Kuttler

The FDA-Approved Drug Nelfinavir Inhibits Lytic Cell-Free but Not Cell-Associated Nonlytic Transmission of Human Adenovirus

Antimicrobial Agents and Chemotherapy
2020-08-20 | Journal article
DOI: 10.1128/aac.01002-20
Part of ISSN: 0066-4804
Part of ISSN: 1098-6596
Source: Self-asserted source
Fabien Kuttler

A high-content image-based drug screen of clinical compounds against cell transmission of adenovirus

Scientific Data
2020-08-12 | Journal article
DOI: 10.1038/s41597-020-00604-0
Contributors: Fanny Georgi; Fabien Kuttler; Luca Murer; Vardan Andriasyan; Robert Witte; Artur Yakimovich; Gerardo Turcatti; Urs F. Greber
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Crossref

Image-Based Marker-Free Screening of GABAA Agonists, Antagonists, and Modulators

SLAS DISCOVERY: Advancing the Science of Drug Discovery
2020-06 | Journal article
DOI: 10.1177/2472555219887142
Part of ISSN: 2472-5552
Part of ISSN: 2472-5560
Source: Self-asserted source
Fabien Kuttler

High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays

Nature Biomedical Engineering
2020-06-08 | Journal article
DOI: 10.1038/s41551-020-0565-2
Contributors: Nathalie Brandenberg; Sylke Hoehnel; Fabien Kuttler; Krisztian Homicsko; Camilla Ceroni; Till Ringel; Nikolce Gjorevski; Gerald Schwank; George Coukos; Gerardo Turcatti et al.
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Crossref

The FDA-approved drug Nelfinavir inhibits lytic cell-free transmission of human adenoviruses

[]
2020-05-15 | Preprint
DOI: 10.1101/2020.05.15.098061
Source: Self-asserted source
Fabien Kuttler

High-content image-based drug screen identifies a clinical compound against cell transmission of adenovirus

[]
2020-03-25 | Preprint
DOI: 10.1101/2020.03.24.006346
Source: Self-asserted source
Fabien Kuttler

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

Proceedings of the National Academy of Sciences
2020-03-03 | Journal article
DOI: 10.1073/pnas.1913904117
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Fabien Kuttler

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

ACS Photonics
2020-01-15 | Journal article
DOI: 10.1021/acsphotonics.9b01152
Part of ISSN: 2330-4022
Part of ISSN: 2330-4022
Source: Self-asserted source
Fabien Kuttler
grade
Preferred source (of 2)‎

The process of Lewy body formation, rather than simply alpha-synuclein fibrillization, is the major driver of neurodegeneration in synucleinopathies

[]
2019-09-02 | Preprint
DOI: 10.1101/751891
Source: Self-asserted source
Fabien Kuttler

Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis

PLOS ONE
2019-01-29 | Journal article
DOI: 10.1371/journal.pone.0211268
Part of ISSN: 1932-6203
Source: Self-asserted source
Fabien Kuttler

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

Journal of Lipid Research
2018 | Journal article
DOI: 10.1194/jlr.d085217
Part of ISSN: 0022-2275
Source: Self-asserted source
Fabien Kuttler

Repositioning approved drugs for the treatment of problematic cancers using a screening approach

PLOS ONE
2017-02-06 | Journal article
DOI: 10.1371/journal.pone.0171052
Part of ISSN: 1932-6203
Source: Self-asserted source
Fabien Kuttler

Digital Holographic Imaging for Label-Free Phenotypic Profiling, Cytotoxicity, and Chloride Channels Target Screening

Methods in Pharmacology and Toxicology
2015 | Book chapter
DOI: 10.1007/978-1-4939-2617-6_17
Part of ISBN: 9781493926169
Part of ISBN: 9781493926176
Part of ISSN: 1557-2153
Part of ISSN: 1940-6053
Contributors: Benjamin Rappaz; Fabien Kuttler; Billy Breton; Gerardo Turcatti
Source: Self-asserted source
Fabien Kuttler

Long-term, multilineage hematopoiesis occurs in the combined absence of β-catenin and γ-catenin

Blood
2008-01-01 | Journal article
DOI: 10.1182/blood-2007-07-102558
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Source: Self-asserted source
Fabien Kuttler

Formation of non-random extrachromosomal elements during development, differentiation and oncogenesis

Seminars in Cancer Biology
2007-02 | Journal article
DOI: 10.1016/j.semcancer.2006.10.007
Part of ISSN: 1044-579X
Source: Self-asserted source
Fabien Kuttler

c-Myc, Genomic Instability and Disease

Genome and Disease
2006 | Book chapter
DOI: 10.1159/000092507
Part of ISBN: 3805580290
Source: Self-asserted source
Fabien Kuttler

c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus

Proceedings of the National Academy of Sciences
2005-07-05 | Journal article
DOI: 10.1073/pnas.0407512102
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Fabien Kuttler

Relationship between expression of genes involved in cell cycle control and apoptosis in diffuse large B cell lymphoma: a preferential survivin–cyclin B link

Leukemia
2002-04 | Journal article
DOI: 10.1038/sj.leu.2402427
Part of ISSN: 0887-6924
Part of ISSN: 1476-5551
Source: Self-asserted source
Fabien Kuttler

c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli

Oncogene
2001-09 | Journal article
DOI: 10.1038/sj.onc.1204827
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Fabien Kuttler

Effect of granulocyte colony-stimulating factor mobilization on phenotypical and functional properties of immune cells

Experimental Hematology
2001-04 | Journal article
DOI: 10.1016/s0301-472x(01)00613-0
Part of ISSN: 0301-472X
Source: Self-asserted source
Fabien Kuttler
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