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Employment (1)

Pennsylvania State University: University Park, PA, US

2018-07 to present | Postdoctoral Scholar
Employment
Source: Self-asserted source
Leah Sigle

Works (11)

Assessing Aedes aegypti candidate genes during viral infection and Wolbachia‐mediated pathogen blocking

Insect Molecular Biology
2022-06 | Journal article
DOI: 10.1111/imb.12764
Contributors: Leah T. Sigle; Matthew Jones; Mario Novelo; Suzanne A. Ford; Nadya Urakova; Konstantinos Lymperopoulos; Richard T. Sayre; Zhiyong Xi; Jason L. Rasgon; Elizabeth A. McGraw
Source: check_circle
Crossref

The IMD and JNK pathways drive the functional integration of the immune and circulatory systems of mosquitoes

2022-01-27 | Preprint
DOI: 10.1101/2022.01.26.477938
Contributors: Yan Yan; Leah T. Sigle; David C. Rinker; Tania Y. Estévez-Lao; John A. Capra; Julián F. Hillyer
Source: check_circle
Crossref

Artificial Selection Finds New Hypotheses for the Mechanism of Wolbachia-Mediated Dengue Blocking in Mosquitoes

Frontiers in Microbiology
2020-07-07 | Journal article
DOI: 10.3389/fmicb.2020.01456
Part of ISSN: 1664-302X
Source: Self-asserted source
Leah Sigle

Nitric oxide produced by periostial hemocytes modulates the bacterial infection induced reduction of the mosquito heart rate

Journal of Experimental Biology
2020-01-01 | Journal article
DOI: 10.1242/jeb.225821
Part of ISSN: 1477-9145
Part of ISSN: 0022-0949
Source: Self-asserted source
Leah Sigle

Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness

Nature Microbiology
2019-11 | Journal article
DOI: 10.1038/s41564-019-0533-3
Part of ISSN: 2058-5276
Source: Self-asserted source
Leah Sigle

Expanding the canon: Non-classical mosquito genes at the interface of arboviral infection

Insect Biochemistry and Molecular Biology
2019-06 | Journal article
DOI: 10.1016/j.ibmb.2019.04.004
Contributors: Leah T. Sigle; Elizabeth A. McGraw
Source: check_circle
Crossref

Eater and draper are involved in the periostial haemocyte immune response in the mosquito Anopheles gambiae

Insect Molecular Biology
2018-08 | Journal article
DOI: 10.1111/imb.12383
Part of ISSN: 0962-1075
Part of ISSN: 1365-2583
Source: Self-asserted source
Leah Sigle

Mosquito Hemocytes Associate With Circulatory Structures That Support Intracardiac Retrograde Hemolymph Flow

Frontiers in Physiology
2018-08-28 | Journal article
DOI: 10.3389/fphys.2018.01187
Part of ISSN: 1664-042X
Source: Self-asserted source
Leah Sigle

Structural and functional characterization of the contractile aorta and associated hemocytes of the mosquito Anopheles gambiae

Journal of Experimental Biology
2018-01-01 | Journal article
DOI: 10.1242/jeb.181107
Part of ISSN: 1477-9145
Part of ISSN: 0022-0949
Source: Self-asserted source
Leah Sigle

An alternative pathway to eusociality: Exploring the molecular and functional basis of fortress defense

Evolution
2017-08 | Journal article
DOI: 10.1111/evo.13285
Part of ISSN: 0014-3820
Part of ISSN: 1558-5646
Source: Self-asserted source
Leah Sigle

Mosquito hemocytes preferentially aggregate and phagocytose pathogens in the periostial regions of the heart that experience the most hemolymph flow

Developmental & Comparative Immunology
2016-02 | Journal article
DOI: 10.1016/j.dci.2015.10.018
Part of ISSN: 0145-305X
Source: Self-asserted source
Leah Sigle

Peer review (1 review for 1 publication/grant)

Review activity for Parasites & vectors. (1)
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