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Scopus Author ID: 7003654548

Countries

Netherlands

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Employment (8)

UMC Utrecht: Utrecht, NL

2016-10-01 to present | Professor (Vascular Surgery)
Employment
Source: Self-asserted source
Dominique de Kleijn

ICIN Netherlands Heart Institute: Utrecht, NL

2010-10-01 to present | Professor
Employment
Source: Self-asserted source
Dominique de Kleijn

UMC Utrecht: Utrecht, NL

2010-10-01 to 2016-10-01 | Professor (Cardiology)
Employment
Source: Self-asserted source
Dominique de Kleijn

National University of Singapore: Singapore, SG

2012-06-01 to 2016-06-01 | Research Professor & Preclinical director CVRI (Surgery)
Employment
Source: Self-asserted source
Dominique de Kleijn

UMC Utrecht: Utrecht, Utrecht, NL

2002-10-01 to 2010-10-01 | Associate professor (Cardiology)
Employment
Source: Self-asserted source
Dominique de Kleijn

ICIN-Netherlands Heart Institute: Utrecht, Utrecht, NL

1996-10-01 to 2010-10-01 | ProjectLeader
Employment
Source: Self-asserted source
Dominique de Kleijn

Netherlands Institute for Neuroscience: Amsterdam, NL

1994-10-01 to 1996-10-01 | Post-doc
Employment
Source: Self-asserted source
Dominique de Kleijn

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

1990-09-01 to 1994-10-01 | PhD student (Molecular Animal Physiology)
Employment
Source: Self-asserted source
Dominique de Kleijn

Education and qualifications (3)

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

1990-09-01 to 1994-09-01 | PhD (Moecular Animal Physiology)
Education
Source: Self-asserted source
Dominique de Kleijn

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

1986-09-01 to 1990-09-01 | MSc in Biochemistry (Molecular Animal Physiology)
Education
Source: Self-asserted source
Dominique de Kleijn

Moller Insitute: Tilburg, NL

1980-09-01 to 1986-09-01 | BSc in Biology and Chemistry
Education
Source: Self-asserted source
Dominique de Kleijn

Funding (3)

Taxinomisis

2018-01 to 2022-01 | Grant
Horizon 2020 Framework Programme (Brussel, BE)
GRANT_NUMBER:

755320
Source: Self-asserted source
Dominique de Kleijn

EXOSOMES FOR DIAGNOSIS AND TREATMENT OF ISCHEMIC HEART DISEASE

2017-12 to 2020-12 | Grant
Nederlandse Hartstichting (Den Haag, NL)
GRANT_NUMBER:

Dekker

Source: Self-asserted source
Dominique de Kleijn

pERSUASIVE

2017-12 to 2020-12 | Grant
Nederlandse Hartstichting (Den Haag, NL)
GRANT_NUMBER: CVON2017-5
Source: Self-asserted source
Dominique de Kleijn

Works (13)

Intraplaque haemorrhage quantification and molecular characterisation using attention based multiple instance learning

2025-03-06 | Preprint
DOI: 10.1101/2025.03.04.25323316
Contributors: Francesco Cisternino; Yipei Song; Tim S. Peters; Roderick Westerman; Gert J. de Borst; Ernest Diez Benavente; Noortje A.M. van den Dungen; Petra H. van der Kraak; Dominique De Kleijn; Joost M. Mekke et al.
Source: check_circle
Crossref

The IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): multicenter pig study on the effect of ischemic preconditioning

Basic Research in Cardiology
2024-10-18 | Journal article
DOI: 10.1007/s00395-024-01083-9
Contributors: Petra Kleinbongard; Carlos Galán Arriola; Lina Badimon; Veronica Crisostomo; Zoltán Giricz; Mariann Gyöngyösi; Gerd Heusch; Borja Ibanez; Attila Kiss; Dominique P. V. de Kleijn et al.
Source: check_circle
Crossref

Atherosclerotic fibrous plaques in females are characterized by endothelial-to-mesenchymal transition and linked to smoking

2024-10-02 | Preprint
DOI: 10.1101/2024.10.01.24314739
Contributors: Tim R. Sakkers; Eloi Mili; Denitsa Meteva; Marian Wesseling; Daniek Kapteijn; Barend M. Mol; Gert J. de Borst; Dominique P.V. de Kleijn; Sander W. van der Laan; Mete Civelek et al.
Source: check_circle
Crossref

Carotid plaques show more unstable characteristics between 2010-2021 after a prior decade of stabilization

2024-08-26 | Preprint
DOI: 10.1101/2024.08.26.24312602
Contributors: Tetiana Motsak; Barend M. Mol; Joost K.R. Hoekstra; Gerard Pasterkamp; Gert J. de Borst; Dominique P.V. de Kleijn
Source: check_circle
Crossref

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans

Arteriosclerosis, Thrombosis, and Vascular Biology
2024-06 | Journal article
DOI: 10.1161/ATVBAHA.123.320692
Contributors: Ernest Diez Benavente; Robin J.G. Hartman; Tim R. Sakkers; Marian Wesseling; Yannicke Sloots; Lotte Slenders; Arjan Boltjes; Barend M. Mol; Gert J. de Borst; Dominique P.V. de Kleijn et al.
Source: check_circle
Crossref

Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue

2023-07-18 | Preprint
DOI: 10.1101/2023.07.18.549599
Contributors: Lotte Slenders; Marian Wesseling; Arjan Boltjes; Daniek M.C. Kapteijn; Marie A.C. Depuydt; Koen Prange; Noortje A.M. van den Dungen; Ernest Diez Benavente; Dominique P.V. de Kleijn; Gert J. de Borst et al.
Source: check_circle
Crossref

Plasma Lipoprotein Lipase Is Associated with Risk of Future Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy

European Journal of Vascular and Endovascular Surgery
2023-05 | Journal article
DOI: 10.1016/j.ejvs.2023.01.035
Contributors: Joost M. Mekke; Maarten C. Verwer; Erik S.G. Stroes; Jeffrey Kroon; Leo Timmers; Gerard Pasterkamp; Gert J. de Borst; Sander W. van der Laan; Dominique P.V. de Kleijn
Source: check_circle
Crossref

Endothelial Damage Arising From High Salt Hypertension Is Elucidated by Vascular Bed Systematic Profiling

Arteriosclerosis, Thrombosis, and Vascular Biology
2023-03 | Journal article
DOI: 10.1161/ATVBAHA.122.318439
Contributors: Arada Vinaiphat; Kalailingam Pazhanchamy; Gnanasekaran JebaMercy; SoFong Cam Ngan; Melvin Khee-Shing Leow; Hee Hwa Ho; Yong-Gui Gao; Kah Leong Lim; A. Mark Richards; Dominique P.V. de Kleijn et al.
Source: check_circle
Crossref

Plasma Extracellular Vesicle Serpin G1 and CD14 Levels are Associated with Major Adverse Cardiovascular Events and Major Adverse Limb Events in Patients Undergoing Femoral Endarterectomy

European Journal of Vascular and Endovascular Surgery
2023-02 | Journal article
DOI: 10.1016/j.ejvs.2022.10.045
Contributors: Maarten C. Verwer; Joost M. Mekke; Nathalie Timmerman; Qiu Y. Van Der Pol; Claire Frissen; Gerard Pasterkamp; Gert J. De Borst; Constantijn E.V.B. Hazenberg; Dominique P.V. De Kleijn
Source: check_circle
Crossref

Atherosclerotic plaque epigenetic age acceleration is characterized by mesenchymal reprogramming and poor prognosis

2023-02-18 | Preprint
DOI: 10.1101/2023.02.16.23286067
Contributors: Robin J. G. Hartman; Ernest Diez Benavente; Lotte Slenders; Arjan Boltjes; Barend M. Mol; Gert J. de Borst; Dominique P. V. de Kleijn; Koen H. M. Prange; Menno P. J. de Winther; Johan Kuiper et al.
Source: check_circle
Crossref

Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy.

Scientific reports
2022-04-01 | Journal article
DOI: 10.1038/s41598-022-09225-6
PMID: 35365690
PMC: PMC8975809
Source: Self-asserted source
Dominique de Kleijn

Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned

BMC Cardiovascular Disorders
2021-12 | Journal article
DOI: 10.1186/s12872-021-01995-7
Contributors: Max J. M. Silvis; Gerardus P. J. van Hout; Aernoud T. L. Fiolet; Mirthe Dekker; Lena Bosch; Martijn M. J. van Nieuwburg; Joyce Visser; Marlijn S. Jansen; Leo Timmers; Dominique P. V. de Kleijn
Source: check_circle
Crossref

Glycophorin C in atherosclerotic plaque is associated with major adverse cardiovascular events after carotid endarterectomy

2021-07-19 | Other
DOI: 10.1101/2021.07.15.21260570
Contributors: Joost M. Mekke; Tim R. Sakkers; Maarten C. Verwer; Noortje A.M. van den Dungen; Y. Song; C. Miller; Gerard Pasterkamp; Michal Mokry; Hester M. den Ruijter; Dominique P. V. de Kleijn et al.
Source: check_circle
Crossref

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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