Biography

A major focus of Koronyo-Hamaoui’s research is investigating the role of innate immune cells – especially peripheral monocytes and macrophages – in CNS repair and regeneration, and the development of immunomodulation-based treatments for Alzheimer’s disease (AD). In addition, she is exploring the pathological changes in the retina specific to AD and their connection to brain pathology for the prospect of early screening and tracking response to therapy. She is a pioneer in identifying the core pathological hallmarks of AD and associated inflammation, vascular damage, and degeneration in the retina of AD patients, including in early-stage cases (MCI due to AD). Her team further developed a breakthrough noninvasive approach for detection of retinal Aβ deposits in living patients using high-resolution retinal optical imaging.