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Works (30)

Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

Brain
2023-03-28 | Journal article
DOI: 10.1093/brain/awad101
SOURCE-WORK-ID:

2013232

PMC: PMC10232278
PMID: 36975162
Part of ISSN: 0006-8950
WOSUID:

WOS:000975336100001
Contributors: Tze How Mok; Akin Nihat; Nour Majbour; Danielle Sequeira; Leah Holm-Mercer; Thomas Coysh; Lee Darwent; Mark Batchelor; Bradley R Groveman; Christina D Orrù et al.
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University College London

Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study

Movement Disorders
2022-07-16 | Journal article
DOI: 10.1002/mds.29152
SOURCE-WORK-ID:

1966418

PMC: PMC9543300
PMID: 35841311
Part of ISSN: 0885-3185
WOSUID:

WOS:000825986700001
Contributors: Danielle Sequeira; Akin Nihat; Tzehow Mok; Thomas Coysh; Peter Rudge; John Collinge; Simon Mead
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University College London

Development of prognostic models for survival and care status in sporadic Creutzfeldt-Jakob disease

Brain Communications
2022-07-04 | Journal article
DOI: 10.1093/braincomms/fcac201
Contributors: Akın Nihat; Janice M Ranson; Dominique Harris; Kirsty McNiven; TzeHow Mok; Peter Rudge; John Collinge; David J Llewellyn; Simon Mead
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Development of novel clinical examination scales for the measurement of disease severity in Creutzfeldt-Jakob disease

Journal of Neurology, Neurosurgery & Psychiatry
2022-04 | Journal article
DOI: 10.1136/jnnp-2021-327722
Contributors: Akin Nihat; Tze How Mok; Hans Odd; Andrew Geoffrey Bourne Thompson; Diana Caine; Kirsty McNiven; Veronica O'Donnell; Selam Tesfamichael; Peter Rudge; John Collinge et al.
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Assessing initial MRI reports for suspected CJD patients

Journal of Neurology
2022-04-01 | Journal article
DOI: 10.1007/s00415-022-11087-x
SOURCE-WORK-ID:

1947754

PMC: PMC9293800
PMID: 35362733
Part of ISSN: 0340-5354
WOSUID:

WOS:000777245700001
Contributors: Aaron Jesuthasan; Danielle Sequeira; Harpreet Hyare; Hans Odd; Peter Rudge; Tze How Mok; Akin Nihat; John Collinge; Simon Mead
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University College London

Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme

Lancet Neurology
2022-04-01 | Journal article
DOI: 10.1016/S1474-4422(22)00082-5
SOURCE-WORK-ID:

1945655

PMID: 35305340
Part of ISSN: 1474-4422
WOSUID:

WOS:000807832700015
Contributors: Simon Mead; A Khalili-Shirazi; C Potter; T Mok; Akin Nihat; Harpreet Hyare; Stephanie Canning; C Schmidt; T Campbell; L Darwent et al.
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University College London

Development of Prognostic Models for Survival and Care Status in Sporadic Creutzfeldt-Jakob disease

2022-02-08 | Preprint
DOI: 10.1101/2022.02.06.22270293
Contributors: Akın Nihat; Janice M. Ranson; Dominique Harris; Kirsty McNiven; Peter Rudge; John Collinge; David J. Llewellyn; Simon Mead
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NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Cells
2021-12-13 | Journal article
DOI: 10.3390/cells10123514
SOURCE-WORK-ID:

1911241

PMC: PMC8700417
PMID: 34944022
Part of ISSN: 2073-4409
WOSUID:

WOS:000735737900001
Contributors: D Mengel; T H Mok; Akin Nihat; W Liu; R A Rissman; D Galasko; Jamie Toombs; Simon Mead; John Collinge; D M Walsh
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University College London

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases

Molecular Psychiatry
2021-10 | Journal article
DOI: 10.1038/s41380-021-01045-w
Contributors: Andrew G. B. Thompson; Prodromos Anastasiadis; Ronald Druyeh; Ines Whitworth; Annapurna Nayak; Akin Nihat; Tze How Mok; Peter Rudge; Jonathan D. F. Wadsworth; Jonathan Rohrer et al.
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Cognitive decline heralds onset of symptomatic inherited prion disease

Brain
2021-04-12 | Journal article
DOI: 10.1093/brain/awaa409
Contributors: Joseph Mole; Simon Mead; Peter Rudge; Akin Nihat; Tzehow Mok; John Collinge; Diana Caine
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Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

Scientific Reports
2021-03-04 | Journal article
DOI: 10.1038/s41598-021-84527-9
SOURCE-WORK-ID:

1852349

PMC: PMC7933407
PMID: 33664355
Part of ISSN: 2045-2322
WOSUID:

WOS:000626140000059
Contributors: Tze How Mok; Akin Nihat; Connie Luk; Danielle Sequeira; Mark Batchelor; Simon Mead; John Collinge; Dr Graham S Jackson
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University College London

Development of novel clinical examination scales for the measurement of disease severity in Creutzfeldt-Jakob disease

2020-11-04 | Other
DOI: 10.1101/2020.11.01.20224089
Contributors: Akin Nihat; Tze How Mok; Hans Odd; Andrew Thompson; Diana Caine; Kirsty McNiven; Veronica O’Donnell; Selam Tesfamichael; Peter Rudge; John Collinge et al.
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Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.

Lancet Neurology
2020-10 | Journal article
DOI: 10.1016/S1474-4422(20)30273-8
SOURCE-WORK-ID:

1814630

PMC: PMC8220892
PMID: 32949544
Part of ISSN: 1474-4422
WOSUID:

WOS:000581119100021
Contributors: Emma Jones; Holger Hummerich; Emmanuelle Viré; James Uphill; Athanasios Dimitriadis; Helen Speedy; Tracy Campbell; Penny Norsworthy; Liam Quinn; JEROME WHITFIELD et al.
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University College London

Cognitive decline heralds onset of symptomatic inherited prion disease

2020-09-15 | Other
DOI: 10.1101/2020.09.14.20194217
Contributors: Joseph Mole; Simon Mead; Peter Rudge; Akin Nihat; Mok Tzehow; John Collinge; Diana Caine
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Crossref
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A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

Nature Communications
2020-08-07 | Journal article
DOI: 10.1038/s41467-020-17655-x
SOURCE-WORK-ID:

1806965

PMC: PMC7414116
PMID: 32769986
Part of ISSN: 2041-1723
WOSUID:

WOS:000561098400013
Contributors: Penny J Norsworthy; Andrew G B Thompson; Tze H Mok; Fernando Guntoro; Luke C Dabin; Akin Nihat; Ross William Paterson; Jonathan Schott; John Collinge; Simon Mead et al.
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University College London

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

PLOS Biology
2020-06-09 | Journal article
DOI: 10.1371/journal.pbio.3000725
Contributors: Emmanuel A. Asante; Giuseppe Legname; Jacqueline M. Linehan; Andrew Tomlinson; Tatiana Jakubcova; Shyma Hamdan; Andrew Grimshaw; Michelle Smidak; Asif Jeelani; Akin Nihat et al.
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Genome-wide association study identifies risk variants for sporadic Creutzfeldt-Jakob disease in STX6 and GAL3ST1

2020-04 | Other
DOI: 10.1101/2020.04.06.20055376
OTHER-ID:

PPR150134
Contributors: Jones E; Hummerich H; Viré E; Uphill J; Dimitriadis A; Speedy H; Campbell T; Norsworthy P; Quinn L; Whitfield J et al.
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

2020-01 | Other
DOI: 10.1101/2020.01.08.19015214
OTHER-ID:

PPR108276
Contributors: Norsworthy PJ; Thompson AGB; Mok TH; Guntoro F; Dabin LC; Nihat A; Paterson RW; Schott JM; Collinge J; Mead S et al.
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process.

NeuroImage. Clinical
2019-10 | Journal article
DOI: 10.1016/j.nicl.2019.102051
PMID: 31734530
PMC: PMC6978211
Contributors: Canas LS; Sudre CH; De Vita E; Nihat A; Mok TH; Slattery CF; Paterson RW; Foulkes AJM; Hyare H; Cardoso MJ et al.
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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Enteral feeding is associated with longer survival in the advanced stages of prion disease

Brain Communications
2019-09-10 | Journal article
DOI: 10.1093/braincomms/fcz012
SOURCE-WORK-ID:

1807834

PMC: PMC7425295
PMID: 32954259
Part of ISSN: 2632-1297
WOSUID:

WOS:000574927100012
Contributors: Kirsty McNiven; Akin Nihat; Tze How Mok; Selam Tesfamichael; Veronica O’Donnell; Peter Rudge; John Collinge; Simon Mead
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University College London

Plasma tau and neurofilament light chain as biomarkers for the human prion diseases: evaluation in a large prospective natural history cohort

Prion
2019-05-15 | Conference abstract
SOURCE-WORK-ID:

1662582

Part of ISSN: 1933-6896
WOSUID:

WOS:000468423900092
Contributors: Andrew G B Thompson; Prodromos Anastasiadis; Akin Nihat; Tze Mok How; Peter Rudge; Amanda Heslegrave; Jamie Toombs; John Collinge; Dr Graham S Jackson; Simon Mead
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University College London

Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare

Genome Medicine
2018-12 | Journal article
DOI: 10.1186/s13073-018-0536-3
Contributors: Akin Nihat; Simon Mead
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The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature

PLOS ONE
2018-01-05 | Journal article
DOI: 10.1371/journal.pone.0190818
Contributors: Diana Caine; Gianluigi Zanusso; Akin Nihat; Philippa Crabb; Peter Rudge; Lisa Cipolotti; John Collinge; Simon Mead
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ASSESSING CEREBELLAR FUNCTION IN PRION DISEASE

Journal of Neurology, Neurosurgery and Psychiatry
2016-12-01 | Conference abstract
DOI: 10.1136/jnnp-2016-315106.222
SOURCE-WORK-ID:

1490536

Part of ISSN: 0022-3050
WOSUID:

WOS:000389472700161
Contributors: Akin Nihat; Tze How Mok; John Collinge; Simon Mead
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University College London

Rheumatoid meningitis.

Practical neurology
2016-08 | Journal article
DOI: 10.1136/practneurol-2015-001306
PMID: 27029468
Contributors: Nihat A; Chinthapalli K; Bridges L; Johns P; Sofat N; Moynihan B
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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What drives quality improvement in chronic kidney disease (CKD) in primary care: process evaluation of the Quality Improvement in Chronic Kidney Disease (QICKD) trial.

BMJ open
2016-04 | Journal article
DOI: 10.1136/bmjopen-2015-008480
PMID: 27053264
PMC: PMC4823455
Contributors: Nihat A; de Lusignan S; Thomas N; Tahir MA; Gallagher H
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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Improving detection and management of visual symptoms after stroke

International Journal of Stroke
2015-12-01 | Conference paper
SOURCE-WORK-ID:

1499783

Part of ISSN: 1747-4930
WOSUID:

WOS:000363731400086
Contributors: Akin Nihat; J Khistria; L Reynolds; A Nitkunan
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University College London

Should we screen all acutely unwell patients for hyperglycaemia? A prospective study at a medical acute admissions unit in the UK

Diabetologia
2012-10-01 | Conference paper
SOURCE-WORK-ID:

1499784

Part of ISSN: 0012-186X
WOSUID:

WOS:000208826502317
Contributors: S Rokadiya; Akin Nihat; M Kostoula; F Keane; B Stroll; J Patel; P Pusalkar
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University College London

Optimization and initial experience of a multisection balanced steady-state free precession cine sequence for the assessment of fetal behavior in utero.

AJNR. American journal of neuroradiology
2011-02 | Journal article
DOI: 10.3174/ajnr.a2295
PMID: 21087938
Contributors: Hayat TT; Nihat A; Martinez-Biarge M; McGuinness A; Allsop JM; Hajnal JV; Rutherford MA
Source: Self-asserted source
Akin Nihat via Europe PubMed Central
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A recent surge of nitrous oxide misuse around London which merits a public health warning

Postgraduate Medical Journal
Journal article
DOI: 10.1093/postmj/qgad121
SOURCE-WORK-ID:

2134736

PMID: 38079632
Part of ISSN: 0032-5473
WOSUID:

WOS:001123105100001
Contributors: Naveed Malek; Akin Nihat; Miriam Mattoscio; Valentina Simioni; Jacquie Deeb; Sanjiv Chawda; Alberto Cifelli; Magdalini Krommyda
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University College London
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