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Emails & domains

Verified email domains

Keywords

human primordial germ cell, developmental biology of the early human embryo, human reproduction and fertility preservation, organoid co-culture

Countries

Portugal, Sweden

Activities

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Employment (3)

Karolinska Institute: Stockholm, SE

2023-01-01 to present | Assistant Professor (Women's and Children's Health)
Employment
Source: Self-asserted source
João Pedro Alves-Lopes

Karolinska Institute: Stockholm, SE

2022-02-01 to 2022-12-31 | Postdoc ( Women's and Children's Health)
Employment
Source: Self-asserted source
João Pedro Alves-Lopes

University of Cambridge: Cambridge, Cambridgeshire, GB

2018-10-01 to 2022-01-31 | Associate Researcher (Wellcome Trust Cancer Research UK Gurdon Institute)
Employment
Source: Self-asserted source
João Pedro Alves-Lopes

Education and qualifications (2)

Karolinska Institutet: Stockholm, SE

2014-12-10 to 2018-08-31 | PhD student (Women's and Children's Health)
Education
Source: Self-asserted source
João Pedro Alves-Lopes

University of Lisbon: Lisbon, PT

2008-09-15 to 2014-02-11 | Master of Pharmaceutical Sciences (Faculty of Pharmacy)
Education
Source: Self-asserted source
João Pedro Alves-Lopes

Works (11)

Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids

Nature Protocols
2024-04 | Journal article
DOI: 10.1038/s41596-023-00945-1
Contributors: João Pedro Alves-Lopes; Frederick C. K. Wong; M. Azim Surani
Source: check_circle
Crossref

Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids.

Cell reports
2023-01 | Journal article
DOI: 10.1016/j.celrep.2022.111907
PMID: 36640324
Contributors: Alves-Lopes JP; Wong FCK; Tang WWC; Gruhn WH; Ramakrishna NB; Jowett GM; Jahnukainen K; Surani MA
Source: Self-asserted source
João Pedro Alves-Lopes via Europe PubMed Central

Epigenetic resetting in the human germ line entails histone modification remodeling

Science Advances
2023-01-20 | Journal article
DOI: 10.1126/sciadv.ade1257
Contributors: Wolfram H. Gruhn; Walfred W.C. Tang; Sabine Dietmann; João P. Alves-Lopes; Christopher A. Penfold; Frederick C. K. Wong; Navin B. Ramakrishna; M. Azim Surani
Source: check_circle
Crossref

Single-cell roadmap of human gonadal development

Nature
2022-07-21 | Journal article
DOI: 10.1038/s41586-022-04918-4
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: João Pedro Alves-Lopes
Source: Self-asserted source
João Pedro Alves-Lopes

Self-organising human gonads generated by a Matrigel-based gradient system

BMC Biology
2021-12 | Journal article
DOI: 10.1186/s12915-021-01149-3
Part of ISSN: 1741-7007
Source: Self-asserted source
João Pedro Alves-Lopes

Spermatogonia Loss Correlates with LAMA 1 Expression in Human Prepubertal Testes Stored for Fertility Preservation

Cells
2021-01-27 | Journal article
DOI: 10.3390/cells10020241
Part of ISSN: 2073-4409
Source: Self-asserted source
João Pedro Alves-Lopes

Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy

Human Reproduction
2018-09-01 | Journal article
DOI: 10.1093/humrep/dey240
Part of ISSN: 0268-1161
Part of ISSN: 1460-2350
Source: Self-asserted source
João Pedro Alves-Lopes

Testicular organoids: a new model to study the testicular microenvironment in vitro?

Human Reproduction Update
2018-03-01 | Journal article
DOI: 10.1093/humupd/dmx036
Contributors: João Pedro Alves-Lopes; Jan-Bernd Stukenborg
Source: check_circle
Crossref

Use of a three-layer gradient system of cells for rat testicular organoid generation

Nature Protocols
2018-02-04 | Journal article
DOI: 10.1038/nprot.2017.140
Contributors: João Pedro Alves-Lopes; Olle Söder; Jan-Bernd Stukenborg
Source: check_circle
Crossref

Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties

Stem Cell Reports
2017 | Journal article
DOI: 10.1016/j.stemcr.2016.11.012
SOURCE-WORK-ID:

135374608

PMID: 28017656
Contributors: Baert, Y; De Kock, J; Alves-Lopes, JP; Söder, O; Stukenborg, JB; Goossens, E
Source: check_circle
Karolinska Institutet

Testicular organoid generation by a novel in vitro three-layer gradient system

Biomaterials
2017 | Journal article
DOI: 10.1016/j.biomaterials.2017.03.025
SOURCE-WORK-ID:

135615419

PMID: 28364632
Contributors: Alves-Lopes, JP; Söder, O; Stukenborg, JB
Source: check_circle
Karolinska Institutet
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