Personal information

breast cancer, CTC, HAX1, RNA-binding

Activities

Employment (1)

Maria Skoldowska-Curie National Research Institute of Oncology: Warszawa, PL

(Molecular and Translational Oncology)
Employment
Source: Self-asserted source
Ewa Grzybowska

Professional activities (1)

Polskie Towarzystwo Biochemiczne: Warsaw, PL

Membership
Source: Self-asserted source
Ewa Grzybowska

Funding (2)

Heterogeneity of circulating tumor cells and CTC clusters in different biological subtypes of breast cancer.

Grant
Narodowe Centrum Nauki (Cracow, PL)
Source: Self-asserted source
Ewa Grzybowska

Towards re-definition of the mechanisms of entotic cell death; the role of HAX1 and SEPT7 in the regulation of entosis in breast cancer models in vivo and in vitro.

Grant
NCN (Cracow, PL)
Source: Self-asserted source
Ewa Grzybowska

Works (38)

The RNA-Binding Landscape of HAX1 Protein Indicates Its Involvement in Translation and Ribosome Assembly

Cells
2022-09-20 | Journal article
Part of ISSN: 2073-4409
Contributors: Ewa Grzybowska; Anna Balcerak; Ewelina Macech-Klicka; Maciej Wakuła; Rafal Tomecki; Krzysztof Goryca; Malgorzata Rydzanicz; Mateusz Chmielarczyk; Malgorzata Szostakowska-Rodzos; Marta Wisniewska et al.
Source: Self-asserted source
Ewa Grzybowska

New 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-N-(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation

International Journal of Molecular Sciences
2022-06-28 | Journal article
Part of ISSN: 1422-0067
Contributors: Ewa Grzybowska; Łukasz Tomorowicz; Beata Żołnowska; Krzysztof Szafrański; Jaroslaw Chojnacki; Ryszard Konopiński; Ewa A. Grzybowska; Jarosław; Anna Kawiak
Source: Self-asserted source
Ewa Grzybowska

Cell Death by Entosis: Triggers, Molecular Mechanisms and Clinical Significance

International Journal of Molecular Sciences
2022-04-30 | Journal article
Part of ISSN: 1422-0067
Contributors: Ewa Grzybowska; Mostafa Kianfar; Anna Balcerak; Mateusz Chmielarczyk; Leszek Tarnowski; Ewa A. Grzybowska
Source: Self-asserted source
Ewa Grzybowska

Editorial: The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies

Frontiers in Molecular Biosciences
2022-01-04 | Journal article
Part of ISSN: 2296-889X
Contributors: Ewa Grzybowska; Roberto Giambruno; Ewa A. Grzybowska; Nicolas L. Fawzi; Dorothee Dormann
Source: Self-asserted source
Ewa Grzybowska

Protein Binding to Cis-Motifs in mRNAs Coding Sequence Is Common and Regulates Transcript Stability and the Rate of Translation

Cells
2021-10-27 | Journal article
Contributors: Ewa A. Grzybowska; Maciej Wakula
Source: check_circle
Crossref
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Preferred source (of 2)‎

Clusters, Assemblies and Aggregates of Tumor Cells in the Blood of Breast Cancer Patients; Composition, Mode of Action, Detection and Impact on Metastasis and Survival

International Journal of Translational Medicine
2021-06-04 | Journal article
Contributors: Urszula Smietanka; Małgorzata Szostakowska-Rodzos; Sylwia Tabor; Anna Fabisiewicz; Ewa A. Grzybowska
Source: check_circle
Crossref
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Preferred source (of 2)‎

The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing

Bioscience Reports
2020-11-27 | Journal article
Contributors: Maciej Wakula; Anna Balcerak; Tymon Rubel; Mateusz Chmielarczyk; Ryszard Konopinski; Filip Lyczek; Ewa A. Grzybowska
Source: check_circle
Crossref

How to Predict Metastasis in Luminal Breast Cancer? Current Solutions and Future Prospects

International Journal of Molecular Sciences
2020-11-09 | Journal article
Contributors: Sylwia Tabor; Małgorzata Szostakowska-Rodzos; Anna Fabisiewicz; Ewa A. Grzybowska
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Quantification of Cell-Substrate Adhesion Area and Cell Shape Distributions in MCF7 Cell Monolayers

Journal of Visualized Experiments
2020-06-24 | Journal article
Part of ISSN: 1940-087X
Source: Self-asserted source
Ewa Grzybowska

Impact of Medium pH on DOX Toxicity toward HeLa and A498 Cell Lines.

ACS Omega
2020-04-01 | Journal article
Source: Self-asserted source
Ewa Grzybowska

Circulating Tumor Cells in Early and Advanced Breast Cancer; Biology and Prognostic Value.

International Journal of Molecular Sciences
2020-02-29 | Journal article
Source: Self-asserted source
Ewa Grzybowska

HAX1 impact on collective cell migration, cell adhesion, and cell shape is linked to the regulation of actomyosin contractility

Molecular Biology of the Cell
2019-12-01 | Journal article
Part of ISSN: 1059-1524
Part of ISSN: 1939-4586
Source: Self-asserted source
Ewa Grzybowska

RNA–protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity

Open Biology
2019-06 | Journal article
Contributors: Anna Balcerak; Alicja Trebinska-Stryjewska; Ryszard Konopinski; Maciej Wakula; Ewa Anna Grzybowska
Source: check_circle
Crossref

Cytoplasmic HAX1 Is an Independent Risk Factor for Breast Cancer Metastasis

2019-04-10 | Journal article
Part of ISSN: 1687-8450
Part of ISSN: 1687-8469
Source: Self-asserted source
Ewa Grzybowska
grade
Preferred source (of 2)‎

Resistance to endocrine therapy in breast cancer: molecular mechanisms and future goals

2019-02 | Journal article
Part of ISSN: 0167-6806
Part of ISSN: 1573-7217
Source: Self-asserted source
Ewa Grzybowska

Calcium-Binding Proteins with Disordered Structure and Their Role in Secretion, Storage, and Cellular Signaling

2018-06-19 | Journal article
Part of ISSN: 2218-273X
Source: Self-asserted source
Ewa Grzybowska

The calcium binding properties and structure prediction of the Hax-1 protein

2017 | Journal article
Part of ISSN: 0001-527X
Part of ISSN: 1734-154X
Source: Self-asserted source
Ewa Grzybowska

CTC clusters in cancer progression and metastasis

Medical Oncology
2017-01 | Journal article
Part of ISSN: 1357-0560
Part of ISSN: 1559-131X
Source: Self-asserted source
Ewa Grzybowska

The putative oncogene, <i>CRNDE</i>, is a negative prognostic factor in ovarian cancer patients

2015-12-22 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Ewa Grzybowska

The Novel Gene CRNDE Encodes a Nuclear Peptide (CRNDEP) Which Is Overexpressed in Highly Proliferating Tissues

2015-05-15 | Journal article
Part of ISSN: 1932-6203
Source: Self-asserted source
Ewa Grzybowska

HAX-1: A Novel P-Body Protein

2015-01 | Journal article
Part of ISSN: 1044-5498
Part of ISSN: 1557-7430
Source: Self-asserted source
Ewa Grzybowska

Exploring the anti-apoptotic role of HAX-1 versus BCL-XLin cytokine-dependent bone marrow-derived cells from mice

2014-08-25 | Journal article
Part of ISSN: 0014-5793
Source: Self-asserted source
Ewa Grzybowska

Comment on “HAX1 Augments Cell Proliferation, Migration, Adhesion, and Invasion Induced by Urokinase-Type Plasminogen Activator Receptor”

Journal of Oncology
2013 | Journal article
Part of ISSN: 1687-8450
Part of ISSN: 1687-8469
Source: Self-asserted source
Ewa Grzybowska

HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing

FEBS Journal
2013-01 | Journal article
Part of ISSN: 1742-464X
Source: Self-asserted source
Ewa Grzybowska

Human intronless genes: Functional groups, associated diseases, evolution, and mRNA processing in absence of splicing

Biochemical and Biophysical Research Communications
2012-07 | Journal article
Part of ISSN: 0006-291X
Source: Self-asserted source
Ewa Grzybowska

HAX-1 overexpression, splicing and cellular localization in tumors

BMC Cancer
2010-12 | Journal article
Part of ISSN: 1471-2407
Source: Self-asserted source
Ewa Grzybowska

Compound heterozygousHAX1mutations in a Swedish patient with severe congenital neutropenia and no neurodevelopmental abnormalities

Pediatric Blood & Cancer
2009-12-01 | Journal article
Part of ISSN: 1545-5009
Part of ISSN: 1545-5017
Source: Self-asserted source
Ewa Grzybowska

HAX-1: A multifunctional protein with emerging roles in human disease

Biochimica et Biophysica Acta (BBA) - General Subjects
2009-10 | Journal article
Part of ISSN: 0304-4165
Source: Self-asserted source
Ewa Grzybowska

Nα-Tosyl-l-phenylalanine Chloromethyl Ketone Induces Caspase-dependent Apoptosis in Transformed Human B Cell Lines with Transcriptional Down-regulation of Anti-apoptotic HS1-associated Protein X-1

Journal of Biological Chemistry
2009-10-09 | Journal article
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Ewa Grzybowska

Hairpin structure within the 3'UTR of DNA polymerase   mRNA acts as a post-transcriptional regulatory element and interacts with Hax-1

Nucleic Acids Research
2007-08-17 | Journal article
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Ewa Grzybowska

Identification and expression analysis of alternative splice variants of the rat Hax-1 gene

Gene
2006-04 | Journal article
Part of ISSN: 0378-1119
Source: Self-asserted source
Ewa Grzybowska

Saccharomyces cerevisiae Ferrochelatase Forms a Homodimer

Archives of Biochemistry and Biophysics
2002-02 | Journal article
Part of ISSN: 0003-9861
Source: Self-asserted source
Ewa Grzybowska

Low Expression of DNA Polymerase β in Human Testicular Germ Cell Tumours: Impact on Foetal Gonocytic Origin Theory

Acta Oncologica
2002-01 | Journal article
Part of ISSN: 0284-186X
Part of ISSN: 1651-226X
Source: Self-asserted source
Ewa Grzybowska

Regulatory Functions of 3′UTRs

Biochemical and Biophysical Research Communications
2001-10 | Journal article
Part of ISSN: 0006-291X
Source: Self-asserted source
Ewa Grzybowska

Probing the Active-site Residues inSaccharomyces cerevisiaeFerrochelatase by Directed Mutagenesis

Journal of Biological Chemistry
1996-05-17 | Journal article
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Ewa Grzybowska

II. Yeast sequencing reports. The sequence of 12·5 kb from the right arm of chromosome II predicts a new N-terminal sequence for the IRA1 protein and reveals two new genes, one of which is a DEAD-box helicase

Yeast
1994-09 | Journal article
Part of ISSN: 0749-503X
Part of ISSN: 1097-0061
Source: Self-asserted source
Ewa Grzybowska

An analysis of the sequence of part of the right arm of chromosome II of S. cerevisiae reveals new genes encoding an amino-acid permease and a carboxypeptidase

Current Genetics
1994-07 | Journal article
Part of ISSN: 0172-8083
Part of ISSN: 1432-0983
Source: Self-asserted source
Ewa Grzybowska

II. Yeast Sequencing Reports. The sequence of 29·7 kb from the right arm of chromosome II reveals 13 complete open reading frames, of which ten correspond to new genes

Yeast
1994-04 | Journal article
Part of ISSN: 0749-503X
Part of ISSN: 1097-0061
Source: Self-asserted source
Ewa Grzybowska