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Scopus Author ID: 55820052400
Scopus Author ID: 57194480054

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Employment (6)

Vall d'Hebron Research Institute: Barcelona, Barcelona, ES

2018-05-15 to present (CIBBIM-Nanomedicine: Drug Delivery and Targeting Group)
Employment
Source: Self-asserted source
Diana Rafael

Vall d'Hebron Research Institute: Barcelona, Barcelona, ES

2016-01-02 to 2018-05-14 | Junior Researcher (CIBBIM-Nanomedicine: Drug Delivery and Targeting Group)
Employment
Source: Self-asserted source
Diana Rafael

Vall d'Hebron Research Institute: Barcelona, Barcelona, ES

2013-11 to 2015-12 | PhD fellow (CIBBIM-Nanomedicine: Drug Delivery and Targeting Group)
Employment
Source: Self-asserted source
Diana Rafael

Faculty of Pharmacy, Lisbon University: Lisbon, Lisbon, PT

2012-01 to 2015-12 | PhD Fellow (iMED.ULisboa - Research Institute for Medicines and Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Diana Rafael

Institut d'Investigacio Biomedica de Bellvitge: Barcelona, ES

2013-04 to 2013-11 | PhD fellow (Molecular Oncology Laboratory)
Employment
Source: Self-asserted source
Diana Rafael

Ludwig-Maximilians-Universitat Munchen: Munchen, Bayern, DE

2012-09 to 2013-01 | PhD fellow (Pharmaceutical Biology – Biotechnology Department of Pharmacy - Centre of Drug Research )
Employment
Source: Self-asserted source
Diana Rafael

Education and qualifications (2)

Faculty of Pharmacy, Lisbon University: Lisbon, PT

2012-01 to 2015-12 | Doctoral Degree in Pharmaceutical Technology (iMED.ULisboa - Research Institute for Medicines and Pharmaceutical Sciences)
Education
Source: Self-asserted source
Diana Rafael

Faculty of Pharmacy, Lisbon University: Lisboa, PT

2005-09 to 2010-12 | Master in Pharmaceutical Sciences
Education
Source: Self-asserted source
Diana Rafael

Works (34)

Influence of agarose in semi-IPN hydrogels for sustained Polymyxin B release

Colloids and Surfaces B: Biointerfaces
2025-03 | Journal article
DOI: 10.1016/j.colsurfb.2024.114431
Contributors: David Filho; Marcelo Guerrero; Ricardo Castro; Diana Rafael; Fernanda Andrade; Adolfo Marican; Oscar Valdes; Esteban Vargas; Elisa Valenzuela; Claudia Mora et al.
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Crossref

Bacterial Polyhydroxyalkanoates-based Therapeutics-delivery Nano-systems

Current Medicinal Chemistry
2024-11 | Journal article
DOI: 10.2174/0109298673268775231003111540
Contributors: Esteban F. Durán-Lara; Diana Rafael; Fernanda Andrade; Olga Lobos G.; Sekar Vijayakumar
Source: check_circle
Crossref

Optimization of Statin-Loaded Delivery Nanoparticles for Treating Chronic Liver Diseases by Targeting Liver Sinusoidal Endothelial Cells

Pharmaceutics
2023-10-14 | Journal article
DOI: 10.3390/pharmaceutics15102463
Contributors: Mar Gil; Lareen Khouri; Imma Raurell; Diana Rafael; Fernanda Andrade; Ibane Abasolo; Simo Schwartz, Jr.; María Martínez-Gómez; María Teresa Salcedo; Juan Manuel Pericàs et al.
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The Nanotechnology-Based Approaches against Kirsten Rat Sarcoma-Mutated Cancers

Pharmaceutics
2023-06-08 | Journal article
DOI: 10.3390/pharmaceutics15061686
Contributors: Fernanda Andrade; Júlia German-Cortés; Sara Montero; Pilar Carcavilla; Diego Baranda-Martínez-Abascal; Marc Moltó-Abad; Joaquín Seras-Franzoso; Zamira Vanessa Díaz-Riascos; Diana Rafael; Ibane Abasolo
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Delivery Systems in Ocular Retinopathies: The Promising Future of Intravitreal Hydrogels as Sustained-Release Scaffolds

Pharmaceutics
2023-05-12 | Journal article
DOI: 10.3390/pharmaceutics15051484
Contributors: Diana Rafael; Marcelo Guerrero; Adolfo Marican; Diego Arango; Bruno Sarmento; Roser Ferrer; Esteban F. Durán-Lara; Simon J. Clark; Simo Schwartz, Jr.
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Solid Lipid Nanoparticles: Multitasking Nano-Carriers for Cancer Treatment

Pharmaceutics
2023-03-03 | Journal article
DOI: 10.3390/pharmaceutics15030831
Contributors: Júlia German-Cortés; Mireia Vilar-Hernández; Diana Rafael; Ibane Abasolo; Fernanda Andrade
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Intracellular Delivery of Anti-Kirsten Rat Sarcoma Antibodies Mediated by Polymeric Micelles Exerts Strong In Vitro and In Vivo Anti-Tumorigenic Activity in Kirsten Rat Sarcoma-Mutated Cancers

ACS Applied Materials & Interfaces
2023-03-01 | Journal article
DOI: 10.1021/acsami.2c19897
Contributors: Diana Rafael; Sara Montero; Pilar Carcavilla; Fernanda Andrade; Júlia German-Cortés; Zamira V. Diaz-Riascos; Joaquin Seras-Franzoso; Monserrat Llaguno; Begoña Fernández; Alfredo Pereira et al.
Source: check_circle
Crossref

Rational Design of Hydrogels for Cationic Antimicrobial Peptide Delivery: A Molecular Modeling Approach

Pharmaceutics
2023-01-31 | Journal article
DOI: 10.3390/pharmaceutics15020474
Contributors: Alfredo Pereira; Elizabeth Valdés-Muñoz; Adolfo Marican; Gustavo Cabrera-Barjas; Sekar Vijayakumar; Oscar Valdés; Diana Rafael; Fernanda Andrade; Paulina Abaca; Daniel Bustos et al.
Source: check_circle
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Pluronic F127-micelles improve the stability and enhance the anticancer stem cell efficacy of citral in breast cancer

Nanomedicine
2021-06-23 | Journal article
DOI: 10.2217/nnm-2021-0013
Contributors: Marwa M Abu-Serie; Fernanda Andrade; Patricia Cámara-Sánchez; Joaquin Seras-Franzoso; Diana Rafael; Zamira V Díaz-Riascos; Petra Gener; Ibane Abasolo; Simó Schwartz, Jr
Source: check_circle
Crossref

Stimuli-Responsive Hydrogels for Cancer Treatment: The Role of pH, Light, Ionic Strength and Magnetic Field

Cancers
2021-03-09 | Journal article
DOI: 10.3390/cancers13051164
Contributors: Fernanda Andrade; Maria Mercé Roca-Melendres; Esteban F. Durán-Lara; Diana Rafael; Simó Schwartz, Jr.
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Crossref
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Extracellular Vesicles as Drug Delivery Systems in Cancer

Pharmaceutics
2020-11-26 | Journal article
DOI: 10.3390/pharmaceutics12121146
Contributors: Laia Hernandez-Oller; Joaquin Seras-Franzoso; Fernanda Andrade; Diana Rafael; Ibane Abasolo; Petra Gener; Simo Schwartz Jr.
Source: check_circle
Crossref
grade
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Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem Cells

Pharmaceutics
2020-02-21 | Journal article
DOI: 10.3390/pharmaceutics12020185
Contributors: Sara Montero; Joaquin Seras-Franzoso; Fernanda Andrade; Francesc Martinez-Trucharte; Mireia Vilar-Hernández; Manuel Quesada; Helena Xandri; Diego Arango; Ibane Abasolo; Diana Rafael et al.
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The Biological Potential Hidden in Inclusion Bodies

Pharmaceutics
2020-02-15 | Journal article
DOI: 10.3390/pharmaceutics12020157
Contributors: Laia Gifre-Renom; Joaquin Seras-Franzoso; Diana Rafael; Fernanda Andrade; Olivia Cano-Garrido; Francesc Martinez-Trucharte; Estefania Ugarte-Berzal; Erik Martens; Lise Boon; Antonio Villaverde et al.
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Pivotal role of AKT2 during dynamic phenotypic change of breast cancer stem cells

Cancers
2019 | Journal article
DOI: 10.3390/cancers11081058
EID:

2-s2.0-85070641378
Contributors: Gener, P.; Rafael, D.; Seras-franzoso, J.; Perez, A.; Pindado, L.A.; Casas, G.; Arango, D.; Fernández, Y.; Díaz-riascos, Z.V.; Abasolo, I. et al.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier
grade
Preferred source (of 2)‎

Sterilization procedure for temperature-sensitive hydrogels loaded with silver nanoparticles for clinical applications

Nanomaterials
2019 | Journal article
DOI: 10.3390/nano9030380
EID:

2-s2.0-85065314616
Contributors: Rafael, D.; Andrade, F.; Martinez-Trucharte, F.; Basas, J.; Seras-Franzoso, J.; Palau, M.; Gomis, X.; Pérez-Burgos, M.; Blanco, A.; López-Fernández, A. et al.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier
grade
Preferred source (of 2)‎

PS-147-Simvastatin-loaded nanoparticles are more effective and less toxic than conventional statins in a pre-clinical model of advanced chronic liver disease

Journal of Hepatology
2019-04 | Journal article
DOI: 10.1016/s0618-8278(19)30165-3
Part of ISSN: 0168-8278
Source: Self-asserted source
Diana Rafael

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Drug Delivery
2018 | Journal article
DOI: 10.1080/10717544.2018.1461276
EID:

2-s2.0-85053736225
Contributors: Rafael, D.; Gener, P.; Andrade, F.; Seras-Franzoso, J.; Montero, S.; Fernandez, Y.; Hidalgo, M.; Arango, D.; Sayos, J.; Florindo, H.F. et al.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Dynamism, sensitivity, and consequences of mesenchymal and stem-like phenotype of cancer cells

Stem Cells International
2018 | Journal article
DOI: 10.1155/2018/4516454
EID:

2-s2.0-85062854892
Contributors: Gener, P.; Seras-Franzoso, J.; Callejo, P.G.; Andrade, F.; Rafael, D.; Martínez, F.; Montero, S.; Arango, D.; Sayós, J.; Abasolo, I. et al.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Efficient EFGR mediated siRNA delivery to breast cancer cells by Cetuximab functionalized Pluronic® F127/Gelatin

Chemical Engineering Journal
2018 | Journal article
DOI: 10.1016/j.cej.2017.12.114
EID:

2-s2.0-85040102188
Contributors: Rafael, D.; Martínez, F.; Andrade, F.; Seras-Franzoso, J.; Garcia-Aranda, N.; Gener, P.; Sayós, J.; Arango, D.; Abasolo, I.; Schwartz, S.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Micellar-Based Nanoparticles for Cancer Therapy and Bioimaging

Nanooncology
2018 | Book chapter
DOI: 10.1007/978-3-319-89878-0_6
Part of ISBN: 9783319898773
Part of ISBN: 9783319898780
Part of ISSN: 2194-0452
Part of ISSN: 2194-0460
Source: Self-asserted source
Diana Rafael

Rational Design of a siRNA Delivery System: ALOX5 and Cancer Stem Cells as Therapeutic Targets

Precision Nanomedicine
2018-06-29 | Journal article
DOI: 10.29016/180629.1
Contributors: Diana Rafael; Fernanda Andrade; Sara Montero; Petra Gener; Joaquin Seras-Franzoso; Francesc Martínez; Patricia González; Helena Florindo; Diego Arango; Joan Sayós et al.
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Crossref

Simvastatin-loaded polymeric micelles are a new, safe and effective drug delivery system targeting liver sinusoidal endothelial cells

Journal of Hepatology
2018-04 | Journal article
DOI: 10.1016/s0168-8278(18)31176-0
Part of ISSN: 0168-8278
Source: Self-asserted source
Diana Rafael

The Emerging Role of Nanomedicine in the Advances of Oncological Treatment

Nanoparticles in Life Sciences and Biomedicine
2018-02 | Book chapter
Source: Self-asserted source
Diana Rafael

Cancer stem cells and personalized cancer nanomedicine

Nanomedicine
2016 | Journal article
DOI: 10.2217/nnm.15.200
EID:

2-s2.0-84956899430
Contributors: Gener, P.; De Sousa Rafael, D.F.; Fernández, Y.; Ortega, J.S.; Arango, D.; Abasolo, I.; Videira, M.; Schwartz, S.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization

International Journal of Pharmaceutics
2016 | Journal article
DOI: 10.1016/j.ijpharm.2016.01.075
EID:

2-s2.0-84961612946
Contributors: Arranja, A.; Gouveia, L.F.; Gener, P.; Rafael, D.F.; Pereira, C.; Schwartz, S.; Videira, M.A.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

EMT blockage strategies: Targeting Akt dependent mechanisms for breast cancer metastatic behaviour modulation

Current Gene Therapy
2015 | Journal article
EID:

2-s2.0-84928941602
Contributors: Rafael, D.; Doktorovová, S.; Florindo, H.F.; Gener, P.; Abasolo, I.; Schwartz, S.; Videira, M.A.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells

Nanomedicine: Nanotechnology, Biology, and Medicine
2015 | Journal article
DOI: 10.1016/j.nano.2015.07.009
EID:

2-s2.0-84951153297
Contributors: Gener, P.; Gouveia, L.P.; Sabat, G.R.; de Sousa Rafael, D.F.; Fort, N.B.; Arranja, A.; Fernández, Y.; Prieto, R.M.; Ortega, J.S.; Arango, D. et al.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

P5.07 * Targeting AKT2 signalling events: improving therapeutic outcomes through cancer stemness modulation

Annals of Oncology
2015-03-01 | Journal article
DOI: 10.1093/annonc/mdv094.5
Part of ISSN: 0923-7534
Part of ISSN: 1569-8041
Source: Self-asserted source
Diana Rafael

Amphiphilic Polymers for Drug Delivery

Encyclopedia Biomedical Polymers and Polymeric Biomaterials
2015-01 | Book chapter
Source: Self-asserted source
Diana Rafael

Lipoplexes and Polyplexes: Gene Delivery Applications.

Encyclopedia of Biomedical Polymers and Polymeric Biomaterials
2015-01 | Journal article
Source: Self-asserted source
Diana Rafael

Preclinical development of siRNA therapeutics: Towards the match between fundamental science and engineered systems

Nanomedicine: Nanotechnology, Biology, and Medicine
2014 | Journal article
DOI: 10.1016/j.nano.2013.11.018
EID:

2-s2.0-84900301713
Contributors: Videira, M.; Arranja, A.; Rafael, D.; Gaspar, R.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids

Journal of Drug Delivery
2013 | Journal article
DOI: 10.1155/2013/897348
Part of ISSN: 2090-3014
Part of ISSN: 2090-3022
Source: Self-asserted source
Diana Rafael

Nanotechnology and pulmonary delivery to overcome resistance in infectious diseases

Advanced Drug Delivery Reviews
2013 | Journal article
DOI: 10.1016/j.addr.2013.07.020
EID:

2-s2.0-84888198111
Contributors: Andrade, F.; Rafael, D.; Videira, M.; Ferreira, D.; Sosnik, A.; Sarmento, B.
Source: Self-asserted source
Diana Rafael via Scopus - Elsevier

Preclinical development of siRNA therapeutics: towards the match between fundamental science and engineered systems

Journal article
Source: Self-asserted source
Diana Rafael

Peer review (3 reviews for 3 publications/grants)

Review activity for ACS applied materials & interfaces. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Pharmaceutics. (1)
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