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SciProfiles: 681595

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Employment (6)

University of the Basque Country: Leioa, ES

2017-09-11 to present | Visiting Professor
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

Ikerbasque, Basque Foundation for Science: Bilbao, ES

2017-09-01 to present | Ikerbasque Fellow
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

University of the Basque Country: Leioa, ES

2016-07-01 to 2017-08-31 | Juan de la Cierva Researcher
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

University of the Basque Country: Leioa, ES

2016-01-23 to 2016-07-01 | Temporary Assistant Professor (Microbiology, Immunology and Parasitology)
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

Columbia University Columbia College: New York, NY, US

2011-01-17 to 2016-01-07 | Postdoctoral Researcher (Microbiology and Immunology)
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

Hospital Universitario Cruces: Barakaldo, País Vasco, ES

2005 to 2010 | PhD Student
Employment
Source: Self-asserted source
Ainara Castellanos Rubio

Education and qualifications (2)

University of the Basque Country: Leioa, ES

2005-07-01 to 2010-10-22 | PhD (Genetics)
Education
Source: Self-asserted source
Ainara Castellanos Rubio

University of the Basque Country: Leioa, ES

2005-06-30 to 2010-10-22 | PhD (Genetics, Physical Antrophology and Animal Physiology)
Qualification
Source: Self-asserted source
Ainara Castellanos Rubio

Professional activities (7)

International Cytokine and Interferon Society: Oradell, NJ, US

2020-05-01 to present
Membership
Source: Self-asserted source
Ainara Castellanos Rubio

RNA Society: Bethesda, Maryland, US

2020-01-03 to present
Membership
Source: Self-asserted source
Ainara Castellanos Rubio

Spanish Association of Gastroenterology (AEG): Madrid, ES

2019-08-01 to present
Membership
Source: Self-asserted source
Ainara Castellanos Rubio

Celiac Disease Association of Spain (SEEC): Valladolid, ES

2008-01-01 to present
Membership
Source: Self-asserted source
Ainara Castellanos Rubio

United European Gastroenterology: Vienna, Vienna, AT

2020 | Rising Star
Distinction
Source: Self-asserted source
Ainara Castellanos Rubio

International Cytokine and Interferon Society: Oridell, US

2020 | Milstein Abstract Award
Distinction
Source: Self-asserted source
Ainara Castellanos Rubio

International Symposium on Frontiers in Molecular Science : Lisbon, PT

2019 | Best poster award
Distinction
Source: Self-asserted source
Ainara Castellanos Rubio

Funding (5)

Brainlinc: Deciphering the mechanisms of the functional homologs of multiple sclerosis associated lncRNA LOC339803 in the rat brain

2021-01 to 2022-12 | Grant
Euskal Herriko Unibertsitatea (Leioa, ES)
GRANT_NUMBER:

COLLAB20/02
Source: Self-asserted source
Ainara Castellanos Rubio

Epitranscriptome, lncRNAs and risk variants: Implication in the development of complex inflammatory diseases

2019-01 to 2023-12 | Grant
Spanish MInistry of Science, Innovation and Universities (Madrid, ES)
GRANT_NUMBER:

PGC2018-097573-A-I00
Source: Self-asserted source
Ainara Castellanos Rubio

Analysis of lnc13 and inflammatory genes in saliva for the diagnosis of celiac disease

2018-12 to 2020-07 | Grant
Spanish Ministry of Science, Innovation and Universities (Madrid, ES)
GRANT_NUMBER:

SAF2017‐91873‐EXP
Source: Self-asserted source
Ainara Castellanos Rubio

Research Award from the Celiac Disease Association of Madrid

2018-01 to 2020-12 | Award
Celiac Disease and gluten sensivitivy association of Madrid (Madrid, ES)
GRANT_NUMBER:

ACM18
Source: Self-asserted source
Ainara Castellanos Rubio

Development of a non invasive method for the diagnosis and prediction of celiac disease

2017-12 to 2021-01 | Grant
Basque Government, Department of Health (San Sebastian, ES)
GRANT_NUMBER:

EJ-2017111082
Source: Self-asserted source
Ainara Castellanos Rubio

Works (41)

Human Colonic Organ Culture Reveals XPO1-Independent Ability of Salvianolic Acid to Reduce Ulcerative Colitis–Related Inflammation

Gastro Hep Advances
2024 | Journal article
DOI: 10.1016/j.gastha.2024.07.014
Contributors: Henar Rojas-Márquez; Ane Olazagoitia-Garmendia; Maria Jesus Perugorria; Alain Huerta; Luis Bujanda; Ainara Castellanos-Rubio
Source: check_circle
Crossref

A Novel, Noninvasive Method to Diagnose Active Eosinophilic Esophagitis, Combining Clinical Data and Oral Cavity RNA Levels

Clinical Gastroenterology and Hepatology
2024-03 | Journal article
DOI: 10.1016/j.cgh.2023.07.023
Contributors: Maialen Sebastian-Delacruz; Koldo Garcia-Etxebarria; Jose ramón Bilbao; Alfredo J. Lucendo; Luis Bujanda; Ainara Castellanos-Rubio
Source: check_circle
Crossref

m6A modified lncRNA WAKMAR2 induces intestinal inflammation through an allele-specific RNA methylation dependent splicing mechanism

2023-12-06 | Preprint
DOI: 10.21203/rs.3.rs-3639115/v1
Contributors: Ainara Castellanos-Rubio; Henar Rojas-Marquez; Ane Olazagoitia-Garmendia; Luis Mendoza-Gomez; Luis Bujanda; Alain Huerta; Izortze Santin
Source: check_circle
Crossref

Functional evolutionary convergence of long noncoding RNAs involved in embryonic development

Communications Biology
2023-09-05 | Journal article
DOI: 10.1038/s42003-023-05278-z
Contributors: Ane Olazagoitia-Garmendia; Rodrigo Senovilla-Ganzo; Fernando García-Moreno; Ainara Castellanos-Rubio
Source: check_circle
Crossref

1 motako diabetesarekin asoziaturiko RNA ez kodetzaile batek mikropeptido bat ekoiztu dezake

2023-05-10 | Conference paper
DOI: 10.26876/ikergazte.v.05.30
Contributors: Izortze Santin Gomez; Ainara Castellanos Rubio; Luis Manuel Mendoza Gomez; Leire Bergara Muguruza; Ane Olazagoitia Garmendia; Henar Rojas Márquez; Koldo Garcia Etxebarria; Jon Mentxaka Salgado
Source: check_circle
Crossref

RNA luze ez kodetzaileak hesteetako hanturazko gaixotasunean

2023-05-10 | Conference paper
DOI: 10.26876/ikergazte.v.04.13
Contributors: Ainara Castellanos Rubio; Izortze Santin Gomez; Alain Huerta Madrigal; Henar Rojas Márquez; Leire Bergara Muguruza; Maialen Sebastian de la Cruz; Ane Olazagoitia Garmendia
Source: check_circle
Crossref

m6A methylated long noncoding RNA regulates proinflammatory response emerging as novel target for IBD

2023-01-17 | Preprint
DOI: 10.1101/2023.01.17.524371
Contributors: Ane Olazagoitia-Garmendia; Henar Rojas-Márquez; Maialen Sebastian-delaCruz; Anne Ochoa; Luis Manuel Mendoza-Gomez; Alain Huerta Madrigal; Izortze Santin; Ainara Castellanos-Rubio
Source: check_circle
Crossref

Functional evolutionary convergence of long noncoding RNAs involved in embryonic development

2022-06-15 | Preprint
DOI: 10.1101/2022.06.15.496228
Contributors: Ane Olazagoitia-Garmendia; Rodrigo Senovilla-Ganzo; Fernando Garcia-Moreno; Ainara Castellanos-Rubio
Source: check_circle
Crossref

The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization

Non-Coding RNA
2021-01 | Journal article | Author
DOI: 10.3390/ncrna7010003
Contributors: MAIALEN SEBASTIAN DE LA CRUZ; Itziar Gonzalez-moro; Ane Olazagoitia-Garmendia; Ainara Castellanos Rubio; IZORTZE SANTIN
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease

Epigenomes
2020-08 | Journal article | Author
DOI: 10.3390/epigenomes4030016
Contributors: MAIALEN SEBASTIAN DE LA CRUZ; Ane Olazagoitia-Garmendia; Itziar Gonzalez-moro; IZORTZE SANTIN; Koldo Garcia-Etxebarria; Ainara Castellanos Rubio
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles.

ACS applied materials & interfaces
2020-06 | Journal article
DOI: 10.1021/acsami.0c03222
PMID: 32464047
Contributors: Castellanos-Rubio I; Rodrigo I; Olazagoitia-Garmendia A; Arriortua O; Gil de Muro I; Garitaonandia JS; Bilbao JR; Fdez-Gubieda ML; Plazaola F; Insausti M
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA.

Proceedings of the National Academy of Sciences of the United States of America
2020-04 | Journal article
DOI: 10.1073/pnas.1914353117
PMID: 32284404
PMC: PMC7183221
Contributors: Gonzalez-Moro I; Olazagoitia-Garmendia A; Colli ML; Cobo-Vuilleumier N; Postler TS; Marselli L; Marchetti P; Ghosh S; Gauthier BR; Eizirik DL et al.
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

MAGI2 Gene Region and Celiac Disease.

Frontiers in nutrition
2019-12 | Journal article
DOI: 10.3389/fnut.2019.00187
PMID: 31921880
PMC: PMC6930898
Contributors: Jauregi-Miguel A; Santin I; Garcia-Etxebarria K; Olazagoitia-Garmendia A; Romero-Garmendia I; Sebastian-delaCruz M; Irastorza I; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

1 motako diabetesari asoziaturiko lncRNAen azterketa funtzionala β-zelulen hanturan eta apoptosian

2019-05-20 | Conference paper
DOI: 10.26876/ikergazte.iii.04.11
Contributors: Izortze Santin Gomez; Ainara Castellanos Rubio; Nora Fernandez Jimenez; Ane Olazagoitia Garmendia; Itziar Gonzalez Moro
Source: check_circle
Crossref

Eritasun zeliakoarekin asoziatutako rs6822844 polimorfismoaren ikerketa funtzionala heste-zeluletan

2019-05-20 | Conference paper
DOI: 10.26876/ikergazte.iii.04.07
Contributors: Jose Ramon Bilbao Catala; Ainara Castellanos Rubio; Iñaki Xarles Irastorza Terradillos; Irati Romero Garmendia; Ane Olazagoitia Garmendia; Maialen Sebastian de la Cruz
Source: check_circle
Crossref

Gaixotasun autoimmuneei asoziaturiko RGS1 eremuko lncRNA baten karakterizazio funtzionala

2019-05-20 | Conference paper
DOI: 10.26876/ikergazte.iii.04.12
Contributors: Ainara Castellanos Rubio; Jose Ramon Bilbao Catala; Maialen Sebastian de la Cruz; Nora Fernandez Jimenez; Ane Olazagoitia Garmendia
Source: check_circle
Crossref

A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation.

Scientific reports
2019-03 | Journal article
DOI: 10.1038/s41598-019-40018-6
PMID: 30862814
PMC: PMC6414506
Contributors: Castellanos-Rubio A; Santin I; Olazagoitia-Garmendia A; Romero-Garmendia I; Jauregi-Miguel A; Legarda M; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Disease-Associated SNPs in Inflammation-Related lncRNAs.

Frontiers in immunology
2019-03 | Journal article
DOI: 10.3389/fimmu.2019.00420
PMID: 30906297
PMC: PMC6418042
Contributors: Castellanos-Rubio A; Ghosh S
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region.

Scientific reports
2019-02 | Journal article
DOI: 10.1038/s41598-018-37746-6
PMID: 30718669
PMC: PMC6362130
Contributors: Fernandez-Jimenez N; Garcia-Etxebarria K; Plaza-Izurieta L; Romero-Garmendia I; Jauregi-Miguel A; Legarda M; Ecsedi S; Castellanos-Rubio A; Cahais V; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway.

Diabetologia
2018-11 | Journal article
DOI: 10.1007/s00125-018-4782-0
PMID: 30478640
Contributors: Dos Santos RS; Marroqui L; Velayos T; Olazagoitia-Garmendia A; Jauregi-Miguel A; Castellanos-Rubio A; Eizirik DL; Castaño L; Santin I
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells.

Journal of pediatric gastroenterology and nutrition
2018-08 | Journal article
DOI: 10.1097/mpg.0000000000001970
PMID: 29601440
Contributors: Santin I; Jauregi-Miguel A; Velayos T; Castellanos-Rubio A; Garcia-Etxebarria K; Romero-Garmendia I; Fernandez-Jimenez N; Irastorza I; Castaño L; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Functional implication of celiac disease associated lncRNAs in disease pathogenesis.

Computers in biology and medicine
2018-08 | Journal article
DOI: 10.1016/j.compbiomed.2018.08.013
PMID: 30126616
Contributors: Olazagoitia-Garmendia A; Santin I; Castellanos-Rubio A
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Subcellular Fractionation from Fresh and Frozen Gastrointestinal Specimens.

Journal of visualized experiments : JoVE
2018-07 | Journal article
DOI: 10.3791/57740
PMID: 30059028
PMC: PMC6126469
Contributors: Romero-Garmendia I; Jauregi-Miguel A; Santin I; Bilbao JR; Castellanos-Rubio A
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Profiling Celiac Disease-Related Transcriptional Changes.

International review of cell and molecular biology
2017-09 | Journal article
DOI: 10.1016/bs.ircmb.2017.07.003
PMID: 29413889
Contributors: Castellanos-Rubio A; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Cytoplasmic Form of Carlr lncRNA Facilitates Inflammatory Gene Expression upon NF-κB Activation.

Journal of immunology (Baltimore, Md. : 1950)
2017-06 | Journal article
DOI: 10.4049/jimmunol.1700023
PMID: 28626066
PMC: PMC5531076
Contributors: Castellanos-Rubio A; Kratchmarov R; Sebastian M; Garcia-Etxebarria K; Garcia L; Irastorza I; Ghosh S
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

A long noncoding RNA associated with susceptibility to celiac disease.

Science (New York, N.Y.)
2016-04 | Journal article
DOI: 10.1126/science.aad0467
PMID: 27034373
PMC: PMC4994711
Contributors: Castellanos-Rubio A; Fernandez-Jimenez N; Kratchmarov R; Luo X; Bhagat G; Green PH; Schneider R; Kiledjian M; Bilbao JR; Ghosh S
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy.

PloS one
2014-01 | Journal article
DOI: 10.1371/journal.pone.0083838
PMID: 24392097
PMC: PMC3879280
Contributors: Axpe E; Lopez-Euba T; Castellanos-Rubio A; Merida D; Garcia JA; Plaza-Izurieta L; Fernandez-Jimenez N; Plazaola F; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Coregulation and modulation of NFκB-related genes in celiac disease: uncovered aspects of gut mucosal inflammation.

Human molecular genetics
2013-10 | Journal article
DOI: 10.1093/hmg/ddt520
PMID: 24163129
PMC: PMC3919015
Contributors: Fernandez-Jimenez N; Castellanos-Rubio A; Plaza-Izurieta L; Irastorza I; Elcoroaristizabal X; Jauregi-Miguel A; Lopez-Euba T; Tutau C; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Angiogenesis-related gene expression analysis in celiac disease.

Autoimmunity
2012-01 | Journal article
DOI: 10.3109/08916934.2011.637531
PMID: 22136669
Contributors: Castellanos-Rubio A; Caja S; Caja S; Irastorza I; Fernandez-Jimenez N; Plaza-Izurieta L; Vitoria JC; Maki M; Lindfors K; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Accuracy in copy number calling by qPCR and PRT: a matter of DNA.

PloS one
2011-12 | Journal article
DOI: 10.1371/journal.pone.0028910
PMID: 22174923
PMC: PMC3236783
Contributors: Fernandez-Jimenez N; Castellanos-Rubio A; Plaza-Izurieta L; Gutierrez G; Irastorza I; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Upregulation of KIR3DL1 gene expression in intestinal mucosa in active celiac disease.

Human immunology
2011-05 | Journal article
DOI: 10.1016/j.humimm.2011.04.008
PMID: 21616111
Contributors: Fernandez-Jimenez N; Santín I; Irastorza I; Plaza-Izurieta L; Castellanos-Rubio A; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Revisiting genome wide association studies (GWAS) in coeliac disease: replication study in Spanish population and expression analysis of candidate genes.

Journal of medical genetics
2011-04 | Journal article
DOI: 10.1136/jmg.2011.089714
PMID: 21490378
Contributors: Plaza-Izurieta L; Castellanos-Rubio A; Irastorza I; Fernández-Jimenez N; Gutierrez G; CEGEC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Analysis of beta-defensin and Toll-like receptor gene copy number variation in celiac disease.

Human immunology
2010-05 | Journal article
DOI: 10.1016/j.humimm.2010.05.012
PMID: 20483368
Contributors: Fernandez-Jimenez N; Castellanos-Rubio A; Plaza-Izurieta L; Gutierrez G; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Long-term and acute effects of gliadin on small intestine of patients on potentially pathogenic networks in celiac disease.

Autoimmunity
2010-03 | Journal article
DOI: 10.3109/08916930903225229
PMID: 19814655
Contributors: Castellanos-Rubio A; Santin I; Martin-Pagola A; Irastorza I; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

A regulatory single nucleotide polymorphism in the ubiquitin D gene associated with celiac disease.

Human immunology
2010-01 | Journal article
DOI: 10.1016/j.humimm.2009.09.359
PMID: 19808075
Contributors: Castellanos-Rubio A; Santin I; Irastorza I; Sanchez-Valverde F; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Exploring the diabetogenicity of the HLA-B18-DR3 CEH: independent association with T1D genetic risk close to HLA-DOA.

Genes and immunity
2009-05 | Journal article
DOI: 10.1038/gene.2009.41
PMID: 19458622
PMC: PMC4447140
Contributors: Santin I; Castellanos-Rubio A; Aransay AM; Gutierrez G; Gaztambide S; Rica I; Vicario JL; Noble JA; Castaño L; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin.

Autoimmunity
2009-01 | Journal article
DOI: 10.1080/08916930802350789
PMID: 19127457
Contributors: Castellanos-Rubio A; Santin I; Irastorza I; Castaño L; Carlos Vitoria J; Ramon Bilbao J
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

The functional R620W variant of the PTPN22 gene is associated with celiac disease.

Tissue antigens
2008-01 | Journal article
DOI: 10.1111/j.1399-0039.2007.01002.x
PMID: 18194365
Contributors: Santin I; Castellanos-Rubio A; Aransay AM; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Combined functional and positional gene information for the identification of susceptibility variants in celiac disease.

Gastroenterology
2007-11 | Journal article
DOI: 10.1053/j.gastro.2007.11.041
PMID: 18241860
Contributors: Castellanos-Rubio A; Martin-Pagola A; Santín I; Hualde I; Aransay AM; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Toll-like receptor 4 (TLR4) gene polymorphisms in celiac disease.

Tissue antigens
2007-10 | Journal article
DOI: 10.1111/j.1399-0039.2007.00945.x
PMID: 17927684
Contributors: Santin I; Castellanos-Rubio A; Hualde I; Castaño L; Vitoria JC; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.

Genes and immunity
2007-01 | Journal article
DOI: 10.1038/sj.gene.6364367
PMID: 17215859
Contributors: Santin I; Castellanos-Rubio A; Perez de Nanclares G; Vitoria JC; Castaño L; Bilbao JR
Source: Self-asserted source
Ainara Castellanos Rubio via Europe PubMed Central

Peer review (10 reviews for 8 publications/grants)

Review activity for Cellular and molecular life sciences (1)
Review activity for Communications biology. (2)
Review activity for Gut (1)
Review activity for International journal of molecular sciences. (1)
Review activity for iScience. (2)
Review activity for Molecular therapy oncolytics. (1)
Review activity for Molecular therapy. (1)
Review activity for Signal transduction and targeted therapy. (1)
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