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University of Utah HSC: Salt Lake City, UT, US

2013-08-01 to present | Research Associate (Metabolomics)
Employment
Source: Self-asserted source
J. Alan Maschek

Works (16)

Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism

Journal of Clinical Investigation
2024-06-03 | Journal article
Contributors: Piyarat Siripoksup; Guoshen Cao; Ahmad A. Cluntun; J. Alan Maschek; Quentinn Pearce; Marisa J. Brothwell; Mi-Young Jeong; Hiroaki Eshima; Patrick J. Ferrara; Precious C. Opurum et al.
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The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis

Journal of Cell Biology
2024-05-06 | Journal article
Contributors: Tianyao Xiao; Alyssa M. English; Zachary N. Wilson; J.Alan. Maschek; James E. Cox; Adam L. Hughes
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Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency

Journal of Lipid Research
2024-03 | Journal article
Contributors: Uzoamaka Nwagbo; Saba Parvez; J. Alan Maschek; Paul S. Bernstein
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Disruption of CFAP418 interaction with lipids causes widespread abnormal membrane-associated cellular processes in retinal degenerations

JCI Insight
2024-01-09 | Journal article
Contributors: Anna M. Clark; Dongmei Yu; Grace Neiswanger; Daniel Zhu; Junhuang Zou; J. Alan Maschek; Thomas Burgoyne; Jun Yang
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Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

Science Advances
2023-02-24 | Journal article
Contributors: Jordan M. Johnson; Alek D. Peterlin; Enrique Balderas; Elahu G. Sustarsic; J. Alan Maschek; Marisa J. Lang; Alejandro Jara-Ramos; Vanja Panic; Jeffrey T. Morgan; Claudio J. Villanueva et al.
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Genetic Screen Uncovers a Dual Role for Phospholipids in Mitochondrial-Derived Compartment Biogenesis

2023-02-18 | Preprint
Contributors: Tianyao Xiao; Alyssa M. English; J. Alan Maschek; James E. Cox; Adam L. Hughes
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Phosphatidylethanolamine facilitates mitochondrial pyruvate entry to regulate metabolic flexibility

2022-11-02 | Preprint
Contributors: Piyarat Siripoksup; Guoshen Cao; Ahmad A. Cluntun; J. Alan Maschek; Quentinn Pearce; Marisa J. Lang; Hiroaki Eshima; Precious C. Opurum; Ziad S. Mahmassani; Eric B. Taylor et al.
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An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice

Science
2022-10-21 | Journal article
Contributors: Joni Nikkanen; Yew Ann Leong; William C. Krause; Denis Dermadi; J. Alan Maschek; Tyler Van Ry; James E. Cox; Ethan J. Weiss; Omer Gokcumen; Ajay Chawla et al.
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Mitochondrial dysfunction in mouse livers depleted of iron chaperone PCBP1

Free Radical Biology and Medicine
2021-11 | Journal article
Contributors: Shyamalagauri Jadhav; Olga Protchenko; Fengmin Li; Ethan Baratz; Minoo Shakoury-Elizeh; Alan Maschek; James Cox; Caroline C. Philpott
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The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder

EMBO reports
2021-10-05 | Journal article
Contributors: Esther Nuebel; Jeffrey T Morgan; Sarah Fogarty; Jacob M Winter; Sandra Lettlova; Jordan A Berg; Yu‐Chan Chen; Chelsea U Kidwell; J Alan Maschek; Katie J Clowers et al.
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Critical Role for Isoprenoids in Apicoplast Biogenesis by Malaria Parasites

2021-08-19 | Other
Contributors: Megan Okada; Krithika Rajaram; Russell P. Swift; Amanda Mixon; John Alan Maschek; Sean T. Prigge; Paul A. Sigala
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Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study

The Journal of Clinical Endocrinology & Metabolism
2021-07-13 | Journal article
Contributors: Rebekah J Nicholson; Annelise M Poss; J Alan Maschek; James E Cox; Paul N Hopkins; Steven C Hunt; Mary C Playdon; William L Holland; Scott A Summers
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Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle

Journal of Clinical Investigation
2021-04-15 | Journal article
Contributors: Patrick J. Ferrara; Xin Rong; J. Alan Maschek; Anthony R.P. Verkerke; Piyarat Siripoksup; Haowei Song; Thomas D. Green; Karthickeyan C. Krishnan; Jordan M. Johnson; John Turk et al.
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Metabolic reprogramming of the myeloid lineage by Schistosoma mansoni infection persists independently of antigen exposure

PLOS Pathogens
2021-01-08 | Journal article
Contributors: Diana Cortes-Selva; De'Broski R. Herbert; Lisa Gibbs; J. Alan Maschek; Marcia Nascimento; Tyler Van Ry; James E. Cox; Eyal Amiel; Keke C. Fairfax
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Schistosoma mansoniinfection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndrome

2020-04-20 | Preprint
Contributors: Diana Cortes-Selva; Lisa Gibbs; J. Alan Maschek; Tyler Van Ry; Bartek Rajwa; James E. Cox; Eyal Amiel; Keke C. Fairfax
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Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease

Journal of Clinical Investigation
2020-01-27 | Journal article
Contributors: Annelise M. Poss; J. Alan Maschek; James E. Cox; Benedikt J. Hauner; Paul N. Hopkins; Steven C. Hunt; William L. Holland; Scott A. Summers; Mary C. Playdon
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Peer review (1 review for 1 publication/grant)

Review activity for Metabolomics. (1)