Personal information

Emails & domains

Verified email addresses

Verified email domains

Websites & social links

FAIM at FMI

Other IDs

Loop profile: 2246485

Keywords

microscopy, facility, image processing, high-content screening

Countries

Switzerland

Activities

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Employment (7)

Friedrich Miescher Institute for Biomedical Research: Basel, Basel-Stadt, CH

2020 to present | Head (Facility for Advanced Imaging and Microscopy)
Employment
Source: Self-asserted source
Laurent Gelman

Friedrich Miescher Institute for Biomedical Research: Basel, Basel-Stadt, CH

2010 to 2020 | co-Head (Facility for Advanced Imaging and Microscopy)
Employment
Source: Self-asserted source
Laurent Gelman

Friedrich Miescher Institute for Biomedical Research: Basel, Basel-Stadt, CH

2009 to 2010 | Head (Light Microscopy Facility)
Employment
Source: Self-asserted source
Laurent Gelman

Friedrich Miescher Institute for Biomedical Research: Basel, Basel-Stadt, CH

2006 to 2009 | Research Assistant (Light Microscopy Facility)
Employment
Source: Self-asserted source
Laurent Gelman

University of Lausanne: Lausanne, CH

2002 to 2006 | Maître-Assistant / Oberassistant (Centre Intégratif de Génomique - Laboratory of Prof. W. Wahli )
Employment
Source: Self-asserted source
Laurent Gelman

Institut de Genetique et de Biologie Moleculaire et Cellulaire Biologie et Génomique structurale: Strasbourg, Grand Est, FR

2000 to 2002 | Post-doc (Laboratory of Prof. P. Chambon)
Employment
Source: Self-asserted source
Laurent Gelman

Laboratoires Fournier GmbH: Heidelberg, DE

1994-09 to 1996-01 | Biochemist
Employment
Source: Self-asserted source
Laurent Gelman

Education and qualifications (4)

University of Strasbourg: Strasbourg, Alsace, FR

1996 to 2000 | Ph.D. (IGBMC)
Education
Source: Self-asserted source
Laurent Gelman

Institut Pasteur: Paris, FR

1993-09 to 1994-09 | Master in Immunology
Education
Source: Self-asserted source
Laurent Gelman

Agro ParisTech: Paris, FR

1990-09 to 1993-09 | Engineer (Biochemistry)
Education
Source: Self-asserted source
Laurent Gelman

Lycée Janson-de-Sailly: Paris, FR

1988-09 to 1990-06 (Math Sup Bio - Math Spé Bio)
Education
Source: Self-asserted source
Laurent Gelman

Works (39)

Illumination Power, Stability, and Linearity Measurements for Confocal and Widefield Microscopes

protocols.io
2023-03-29 | Journal article | Author
DOI: dx.doi.org/10.17504/protocols.io.5jyl853ndl2w/v2
Contributors: Nathalie Gaudreault; Rizwan Ali; Sergiy V. Avilov; Steve Bagley; Rodrigo R Bammann; Fabio Barachati; Cristina Bertocchi; Ulrike Boehm; Manel Bosch; Craig Brideau et al.
Source: check_circle
protocols.io

Cohesin and CTCF control the dynamics of chromosome folding.

Nature genetics
2022-12-05 | Journal article
DOI: 10.1038/s41588-022-01232-7
PMID: 36471076
PMC: PMC9729113
Contributors: Pia Mach; Pavel Kos; yinxiu zhan; Julie Cramard; Gaudin S; Tünnermann J; Marchi E; Jan Eglinger; Zuin J; Kryzhanovska M et al.
Source: Self-asserted source
Laurent Gelman

Monitoring the point spread function for quality control of confocal microscopes

protocols.io
2022-10-19 | Journal article | Author
DOI: dx.doi.org/10.17504/protocols.io.bp2l61ww1vqe/v1
Contributors: Glyn Nelson; Ioannis Alexopoulos; Maria Manuela Azevedo; Yury Belyaev; Carvalho, M. T.; Yann Cesbron; Aurelien Dauphin; Alexander Corbett; Ian Dobbie; Laurent Gelman et al.
Source: check_circle
protocols.io

QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy.

Nature methods
2021-12-01 | Journal article
DOI: 10.1038/s41592-021-01162-y
PMID: 34021279
PMC: PMC9443067
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy.

Journal of microscopy
2021-08-11 | Journal article
DOI: 10.1111/jmi.13041
PMID: 34214188
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.

Molecular cell
2019-06-25 | Journal article
DOI: 10.1016/j.molcel.2019.06.002
PMID: 31253574
PMC: PMC6695476
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production.

Nature communications
2018-07-27 | Journal article
DOI: 10.1038/s41467-018-05387-y
PMID: 30054480
PMC: PMC6063938
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

H3K9 methylation extends across natural boundaries of heterochromatin in the absence of an HP1 protein.

The EMBO journal
2015-10-05 | Journal article
DOI: 10.15252/embj.201591320
PMID: 26438724
PMC: PMC4682641
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis.

The international journal of biochemistry & cell biology
2010-07-17 | Journal article
DOI: 10.1016/j.biocel.2010.07.001
PMID: 20621196
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.

Environmental health perspectives
2010-02-01 | Journal article
DOI: 10.1289/ehp.0901217
PMID: 20123618
PMC: PMC2831923
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress.

Scandinavian journal of medicine & science in sports
2009-04-20 | Journal article
DOI: 10.1111/j.1600-0838.2009.00928.x
PMID: 19422655
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

From mechanotransduction to extracellular matrix gene expression in fibroblasts.

Biochimica et biophysica acta
2009-01-31 | Journal article
DOI: 10.1016/j.bbamcr.2009.01.012
PMID: 19339214
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Direct protein-protein interaction of 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen.

Biochimica et biophysica acta
2008-03-12 | Journal article
DOI: 10.1016/j.bbamcr.2008.03.001
PMID: 18381077
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Tenascin-C induction by cyclic strain requires integrin-linked kinase.

Biochimica et biophysica acta
2008-01-26 | Journal article
DOI: 10.1016/j.bbamcr.2008.01.013
PMID: 18269918
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Ligand-dependent transcriptional activities of four torafugu pufferfish Takifugu rubripes peroxisome proliferator-activated receptors.

General and comparative endocrinology
2007-06-12 | Journal article
DOI: 10.1016/j.ygcen.2007.05.034
PMID: 17632107
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

The Journal of biological chemistry
2007-04-27 | Journal article
DOI: 10.1074/jbc.m702724200
PMID: 17468099
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Molecular basis of selective PPARgamma modulation for the treatment of Type 2 diabetes.

Biochimica et biophysica acta
2007-03-16 | Journal article
DOI: 10.1016/j.bbalip.2007.03.004
PMID: 17459763
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior.

The Journal of biological chemistry
2007-01-02 | Journal article
DOI: 10.1074/jbc.m610523200
PMID: 17200111
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Association with coregulators is the major determinant governing peroxisome proliferator-activated receptor mobility in living cells.

The Journal of biological chemistry
2006-12-12 | Journal article
DOI: 10.1074/jbc.m608172200
PMID: 17164241
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Integrating nuclear receptor mobility in models of gene regulation.

Nuclear receptor signaling
2006-04-28 | Journal article
DOI: 10.1621/nrs.04010
PMID: 16741568
PMC: PMC1472671
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.

Progress in lipid research
2006-01-25 | Journal article
DOI: 10.1016/j.plipres.2005.12.002
PMID: 16476485
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity.

Journal of molecular endocrinology
2005-12-01 | Journal article
DOI: 10.1677/jme.1.01856
PMID: 16326836
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman
grade
Preferred source (of 2)‎

PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs.

Microscopy research and technique
2005-09-01 | Journal article
DOI: 10.1002/jemt.20215
PMID: 16208719
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.

Molecular endocrinology (Baltimore, Md.)
2005-05-12 | Journal article
DOI: 10.1210/me.2005-0068
PMID: 15890673
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.

Current opinion in cell biology
2005-04-01 | Journal article
DOI: 10.1016/j.ceb.2005.02.002
PMID: 15780600
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.

The Journal of biological chemistry
2005-02-24 | Journal article
DOI: 10.1074/jbc.m500786200
PMID: 15731109
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

In vivo activation of PPAR target genes by RXR homodimers.

The EMBO journal
2004-04-22 | Journal article
DOI: 10.1038/sj.emboj.7600209
PMID: 15103326
PMC: PMC424365
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.

The Journal of biological chemistry
2003-12-29 | Journal article
DOI: 10.1074/jbc.m312288200
PMID: 14701856
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism.

Molecular endocrinology (Baltimore, Md.)
2002-06-01 | Journal article
DOI: 10.1210/mend.16.6.0843
PMID: 12040021
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity.

Molecular cell
2001-10-01 | Journal article
DOI: 10.1016/s1097-2765(01)00353-7
PMID: 11684010
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Induction of LPL gene expression by sterols is mediated by a sterol regulatory element and is independent of the presence of multiple E boxes.

Journal of molecular biology
2000-12-01 | Journal article
DOI: 10.1006/jmbi.2000.4218
PMID: 11090277
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression.

Genomics
2000-06-01 | Journal article
DOI: 10.1006/geno.2000.6191
PMID: 10873384
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARalpha activation.

Journal of lipid research
1999-11-01 | Journal article
PMID: 10553013
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism.

Molecular and cellular biology
1999-08-01 | Journal article
DOI: 10.1128/mcb.19.8.5495
PMID: 10409739
PMC: PMC84391
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Peroxisome proliferator-activated receptors: mediators of a fast food impact on gene regulation.

Current opinion in clinical nutrition and metabolic care
1999-07-01 | Journal article
DOI: 10.1097/00075197-199907000-00010
PMID: 10453311
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman
grade
Preferred source (of 2)‎

An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer.

Cellular and molecular life sciences : CMLS
1999-06-01 | Journal article
DOI: 10.1007/s000180050345
PMID: 10412372
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

The Journal of biological chemistry
1999-03-01 | Journal article
DOI: 10.1074/jbc.274.12.7681
PMID: 10075656
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

Coordinated regulation in human T cells of nucleotide-hydrolyzing ecto-enzymatic activities, including CD38 and PC-1. Possible role in the recycling of nicotinamide adenine dinucleotide metabolites.

Journal of immunology (Baltimore, Md. : 1950)
1996-08-01 | Journal article
PMID: 8759717
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman

The lymphocyte surface antigen CD38 acts as a nicotinamide adenine dinucleotide glycohydrolase in human T lymphocytes.

European journal of immunology
1993-12-01 | Journal article
DOI: 10.1002/eji.1830231245
PMID: 8258350
Contributors: Laurent Gelman
Source: Self-asserted source
Laurent Gelman
How many people are using ORCID?