Khuzwayo Jere (0000-0003-3376-8529)

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Dr. Khuzwayo C. Jere is a Senior Lecturer in Medical Virology at the University of Liverpool and Kamuzu University of Health Sciences. He leads the Virology Research Group at the Malawi-Liverpool Wellcome Research Programme (MLW), overseas the Diarrhoea Surveillance Programme in Malawi, co-founded the African Enteric Viruses Genome Initiative (AEVGI), and is a core member of the Malawi National Immunization Technical Advisory Group (MAITAG). His research centers on the evolution of gastrointestinal pathogens and the immune responses they elicit through natural infection and vaccination. Additionally, he is actively involved in evaluating new rotavirus vaccine candidates through clinical trials and assessing the effectiveness of existing rotavirus vaccines in low-income settings. Dr. Jere currently leads several multi-country studies focused on rotavirus sequencing and immune responses.

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University of Liverpool: Liverpool, Merseyside, GB

2022-10-01 to present | Senior Lecturer (Institute of Infection, Veterinary and Ecological Sciences, Department of Clinical Infection, Microbiology and Immunology)

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Khuzwayo Jere

https://orcid.org/0000-0003-3376-8529

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Employment (7)

University of Liverpool: Liverpool, Merseyside, GB

University of Liverpool: Liverpool, GB

Malawi Liverpool Wellcome Trust Research Programme: Blantyre, South, MW

University of Malawi College of Medicine: Blantyre, Southern Region, MW

University of Liverpool: Liverpool, Merseyside, GB

University of Liverpool: Liverpool, Merseyside, GB

University of Liverpool: Liverpool, Liverpool, GB

Education and qualifications (1)

North-West University: Potchefstroom, ZA

Works (50 of 59)

Cost-effectiveness analysis of alternative infant and neonatal rotavirus vaccination schedules in Malawi

Age-specific immunity to rotavirus infection and the risk of disease before and after rotavirus vaccine introduction in the United Kingdom: an observational, seroepidemiological study

Cost-effectiveness Analysis of Alternative Infant and Neonatal Rotavirus Vaccination Schedules in Malawi

Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in Malawi

Draft genomes of Aeromonas caviae from patients with cholera-like illness during the 2022–2023 cholera outbreak in Malawi

Examination of ELISA against PCR for assessing treatment efficacy against Cryptosporidium in a clinical trial context

Association Between Maternal Breastmilk Microbiota Composition and Rotavirus Vaccine Response in African, Asian, and European Infants: A Prospective Cohort Study

Increased bacterial taxonomic and functional diversity is associated with impaired rotavirus vaccine immunogenicity in infants from India and Malawi

Association between maternal breastmilk microbiota composition and rotavirus vaccine response in African, Asian, and European infants: a prospective cohort study

Maintaining Momentum for Rotavirus Immunization in Africa during the COVID-19 Era: Report of the 13th African Rotavirus Symposium

Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines

Reduction in Severity of All-Cause Gastroenteritis Requiring Hospitalisation in Children Vaccinated against Rotavirus in Malawi

Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa

Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance

High SARS-CoV-2 seroprevalence in health care workers but relatively low numbers of deaths in urban Malawi [version 2; peer review: 2 approved]

High SARS-CoV-2 seroprevalence in health care workers but relatively low numbers of deaths in urban Malawi

High SARS-CoV-2 seroprevalence in Health Care Workers but relatively low numbers of deaths in urban Malawi

Report of the 1st African Enteric Viruses Genome Initiative (AEVGI) Data and Bioinformatics Workshop on whole-genome analysis of some African rotavirus strains held in Bloemfontein, South Africa

Uncovering the First Atypical DS-1-like G1P[8] Rotavirus Strains That Circulated during Pre-Rotavirus Vaccine Introduction Era in South Africa

Clofazimine for treatment of cryptosporidiosis in HIV-infected adults (CRYPTOFAZ): an experimental medicine, randomized, double-blind, placebo-controlled phase 2a trial.

Community transmission of rotavirus infection in a vaccinated population in Malawi: a prospective household cohort study

Duration and Density of Fecal Rotavirus Shedding in Vaccinated Malawian Children With Rotavirus Gastroenteritis.

Epidemiology and genotype diversity of norovirus infections among children aged <5 years following rotavirus vaccine introduction in Blantyre, Malawi.

Nonsecretor Histo-blood Group Antigen Phenotype Is Associated With Reduced Risk of Clinical Rotavirus Vaccine Failure in Malawian Infants.

Vaccine Effectiveness against DS-1-Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013-2015.

Evaluating strategies to improve rotavirus vaccine impact during the second year of life in Malawi

Etiology of Diarrhea Among Hospitalized Children in Blantyre, Malawi, Following Rotavirus Vaccine Introduction: A Case-Control Study.

Evidence of reduction of rotavirus diarrheal disease after rotavirus vaccine introduction in national immunization programs in the African countries: Report of the 11th African rotavirus symposium held in Lilongwe, Malawi

Infrequent Transmission of Monovalent Human Rotavirus Vaccine Virus to Household Contacts of Vaccinated Infants in Malawi.

Molecular epidemiology of G12 rotavirus strains during eight consecutive epidemic seasons in the Basque Country (North of Spain), 2010-2018.

Direct and possible indirect effects of vaccination on rotavirus hospitalisations among children in Malawi four years after programmatic introduction.

A47 Whole-genome analysis of rotaviruses isolated from humans and domestic animals in Uganda, 2012–2014 reveals possible anthroponosis and multiple rotavirus reasortment events between species.

Emergence of Double- and Triple-Gene Reassortant G1P[8] Rotaviruses Possessing a DS-1-Like Backbone after Rotavirus Vaccine Introduction in Malawi

Whole genome analysis of selected human and animal rotaviruses identified in Uganda from 2012 to 2014 reveals complex genome reassortment events between human, bovine, caprine and porcine strains.

Rotavirus antigen, cytokine, and neutralising antibody profiles in sera of children with and without HIV infection in Blantyre, Malawi.

Whole-genome characterisation of G12P[6] rotavirus strains possessing two distinct genotype constellations co-circulating in Blantyre, Malawi, 2008.

Emergence and spread of G3P[8] rotaviruses possessing an equine-like VP7 and a DS-1-like genetic backbone in the Basque Country (North of Spain), 2015.

Cost-Effectiveness of Monovalent Rotavirus Vaccination of Infants in Malawi: A Postintroduction Analysis Using Individual Patient-Level Costing Data.

Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses.

The quality and diagnostic value of open narratives in verbal autopsy: a mixed-methods analysis of partnered interviews from Malawi.

Determination of a viral load threshold to distinguish symptomatic versus asymptomatic rotavirus infection in a high-disease-Burden African population

Effectiveness of a monovalent rotavirus vaccine in infants in Malawi after programmatic roll-out: An observational and case-control study

Methods and challenges in measuring the impact of national pneumococcal and rotavirus vaccine introduction on morbidity and mortality in Malawi

Whole genome detection of rotavirus mixed infections in human, porcine and bovine samples co-infected with various rotavirus strains collected from sub-Saharan Africa

Methodological challenges in measuring vaccine effectiveness using population cohorts in low resource settings.

Chimaeric virus-like particles derived from consensus genome sequences of human rotavirus strains co-circulating in Africa

Genetic diversity of rotavirus genome segment 6 (encoding VP6) in Pretoria, South Africa

Novel NSP1 genotype characterised in an African camel G8P[11] rotavirus strain

Whole-genome analyses of DS-1-like human G2P[4] and G8P[4] rotavirus strains from Eastern, Western and Southern Africa

Sequence analysis of the whole genomes of five African human G9 rotavirus strains

Peer review (1 review for 1 publication/grant)