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Employment (7)

King's College London: London, GB

Employment
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King's College London

King's College London: London, London, GB

2020 to present | Professor of Pharmacology & Neuroscience (Pharmacology and Neuroscience)
Employment
Source: Self-asserted source
Susan Duty

King's College London: London, London, GB

2004 to 2012 | Senior Lecturer in Pharmacology (Pharmacology )
Employment
Source: Self-asserted source
Susan Duty

King's College London: London, London, GB

1995 to 2004 | Lecturer in Pharmacology (Pharmacology )
Employment
Source: Self-asserted source
Susan Duty

University of Manchester: Manchester, Manchester, GB

1993 to 1995 | Post-doctoral research associate (Anatomy)
Employment
Source: Self-asserted source
Susan Duty

University of Sydney: Sydney, NSW, AU

1991 to 1993 | Post-doctoral research associate (Physiology )
Employment
Source: Self-asserted source
Susan Duty

University of Manchester: Manchester, Manchester, GB

1990 to 1991 | Post doctoral research associate (Pharmacology )
Employment
Source: Self-asserted source
Susan Duty

Education and qualifications (2)

University of Manchester: Manchester, Manchester, GB

1987 to 1990 | PhD (Pharmacology)
Education
Source: Self-asserted source
Susan Duty

University of Manchester: Manchester, Manchester, GB

1984 to 1987 | BSc Physiology and Pharmacology (Pharmacology)
Education
Source: Self-asserted source
Susan Duty

Funding (1)

Boosting endogenous fibroblast growth factor 20 levels in the nigrostriatal tract to achieve neuroprotection and repair in Parkinson’s

Works (39)

Periaqueductal grey and spinal cord pathology contribute to pain in Parkinson’s disease

npj Parkinson's Disease
2023-04-26 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Yazead Buhidma; Carl Hobbs; Marzia Anna Maria Malcangio; Susan Duty
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King's College London

A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson’s Disease

Pharmaceutics
2022-07 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85133228710

Contributors: Emily Clarke; Pawel Stocki; Elizabeth H. Sinclair; Aziz Gauhar; Edward J.R. Fletcher; Alicja Krawczun-Rygmaczewska; Susan Duty; Frank S. Walsh; Patrick Doherty; Julia Lynn Rutkowski
Source: check_circle
King's College London

Drug repurposing strategies of relevance for Parkinson’s disease

Pharmacology Research and Perspectives
2021-08 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Edward J.R. Fletcher; Thomas Kaminski; Gareth Williams; Susan Duty
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King's College London

Potential of animal models for advancing the understanding and treatment of pain in Parkinson's disease

Nature Parkinson's Journal
2020-12-01 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85084784857

Contributors: Susan Duty; Yazead Buhidma; Katarina Rukavina; Kallol Ray Chaudhuri
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King's College London

Neuroanatomical and Microglial Alterations in the Striatum of Levodopa-Treated, Dyskinetic Hemi-Parkinsonian Rats

Frontiers in Neuroscience
2020-09-15 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Edward J R Fletcher; Clare J Finlay; Ana Amor Lopez; William Crum; Anthony Christopher Vernon; Susan Duty
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King's College London

Antiparkinsonian effects of a metabotropic glutamate receptor 4 agonist in MPTP-treated marmosets

Journal of parkinsons disease
2020-07-28 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85089128468

Contributors: Lizzie Mann; Michael Jackson; Louise Lincoln; Ria Fisher; SARAH ROSE; Susan Duty
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King's College London

Chondroitinase ABC reduces dopaminergic nigral cell death and striatal terminal loss in a 6-hydroxydopamine partial lesion mouse model of Parkinson's disease

BMC NEUROSCIENCE
2019-12-20 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Edward J R Fletcher; Prof. Lawrence DF Moon; Susan Duty
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King's College London

Pain in Parkinson's disease

Current Opinion in Neurology
2019-08-01 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85069260626

Contributors: Katarina Rukavina; Valentina Leta; Carolina Sportelli; Yazead Buhidma; Susan Duty; Marzia Anna Maria Malcangio; Kallol Ray Chaudhuri
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King's College London

Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats.

Scientific Reports
2019-06-06 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85066939020

Contributors: Susan Duty; Edward Joseph Richard Fletcher; Gareth Williams; Patrick Doherty; Aran Jamieson
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King's College London

Fibroblast growth factor 20 is protective towards dopaminergic neurons in vivo in a paracrine manner

Neuropharmacology
2018-07-15 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-85048004735

Contributors: Susan Duty; Eugene L Boshoff; Edward J Fletcher
Source: check_circle
King's College London

Animal models of movement disorders

Movement Disorders Curricula
2017-01-01 | Book chapter | Author
SOURCE-WORK-ID:

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EID:

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Part of ISBN: 9783709116289
Part of ISBN: 9783709116272
Contributors: Susan Duty; Peter Jenner
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King's College London

Therapeutic potential of targeting glutamate receptors in Parkinson’s disease

Journal of neural transmission (Vienna, Austria : 1996)
2014-08-01 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-84925781042

Contributors: Clare Finlay; Susan Duty
Source: check_circle
King's College London

Brain morphometry and the neurobiology of levodopa-induced dyskinesias

Frontiers in Neurology
2014-06-11 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Clare J Finlay; Susan Duty; Anthony Christopher Vernon
Source: check_circle
King's College London

Fibroblast growth factor-20 protects against dopamine neuron loss in vitro and provides functional protection in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

Neuropharmacology
2012-12 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: Isobel J. Sleeman; Eugene L. Boshoff; Susan Duty
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King's College London

Targeting glutamate receptors to tackle the pathogenesis, clinical symptoms and levodopa-induced dyskinesia associated with Parkinson's disease

CNS Drugs
2012-12 | Journal article | Author
SOURCE-WORK-ID:

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EID:

2-s2.0-84873417885

Contributors: Susan Duty
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King's College London

Allosteric modulation of the group III mGlu4 receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson’s disease

British Journal of Pharmacology
2012-08 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: Matt Betts; Michael J O'Neill; Susan Duty
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King's College London

Riluzole neuroprotection in a parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation

BMC NEUROSCIENCE
2012-04-05 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: Marica Carbone; Susan Duty; Marcus Rattray
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King's College London

Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata

British Journal of Pharmacology
2012-02 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

000299469600002

EID:

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Contributors: M. Broadstock; P. J. Austin; M. J. Betts; Susan Duty
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King's College London

Riluzole elevates GLT-1 activity and levels in striatal astrocytes

Neurochemistry International
2012-01 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: Marica Carbone; Susan Duty; Marcus Rattray
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King's College London

Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease

British Journal of Pharmacology
2011-10 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: Susan Duty; Peter Jenner
Source: check_circle
King's College London

Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease (vol 160, pg 1741, 2010)

British Journal of Pharmacology
2011-07 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: P. J. Austin; M. J. Betts; M. Broadstock; M. J. O'Neill; S. N. Mitchell; Susan Duty
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King's College London

Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease

British Journal of Pharmacology
2010-09 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: Susan Duty
Source: check_circle
King's College London

Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease

British Journal of Pharmacology
2010-08 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: P. J. Austin; M. J. Betts; M. Broadstock; M. J. O'Neill; S. N. Mitchell; Susan Duty
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King's College London

Group III metabotropic glutamate receptors act as hetero-receptors modulating evoked GABA release in the globus pallidus in vivo

European Journal of Pharmacology
2008-02-02 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: N MacInnes; Susan Duty
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King's College London

Nicotine, but neither the alpha(4)beta(2) ligand RJR2403 nor an alpha 7 nAChR subtype selective agonist, protects against a partial 6-hydroxydopamine lesion of the rat median forebrain bundle

Neuropharmacology
2006-09 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: N P Visanji; M J O'Neill; Susan Duty
Source: check_circle
King's College London

Chronic pre-treatment with nicotine enhances nicotine-evoked striatal dopamine release and a6 and b3 nicotine acetylcholine receptor subumit mRNA in the substantia nigra pars compacta of the rat

Neuropharmacology
2006-01 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: N P Visanji; S N Mitchell; M J O'Neill; Susan Duty
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King's College London

Locomotor effects of imidazoline I-2-site-specific ligands and monoamine oxidase inhibitors in rats with a unilateral 6-hydroxydopamine lesion of the nigrostriatal pathway

British Journal of Pharmacology
2004-12 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: N MacInnes; Susan Duty
Source: check_circle
King's College London

Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat

British Journal of Pharmacology
2004-01 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: N MacInnes; M J Messenger; Susan Duty
Source: check_circle
King's College London

Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson's disease

Experimental Neurology
2003-10-01 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: B Henry; Susan Duty; S H Fox; A R Crossman; J M Brotchie
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King's College London

Changes in GABA(B) receptor mRNA expression in the rodent basal ganglia and thalamus following lesion of the nigrostriatal pathway

Neuroscience
2003-09-15 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: T Johnston; Susan Duty
Source: check_circle
King's College London

GABA(B) receptor agonists reverse akinesia following intranigral or intracerebroventricular injection in the reserpine-treated rat

British Journal of Pharmacology
2003-08 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

2-s2.0-0141428772

Contributors: T Johnston; Susan Duty
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King's College London

Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease

Pharmacology Biochemistry and Behavior
2002 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: T K Murray; M J Messenger; M A Ward; S Woodhouse; D J Osborne; Susan Duty; M J O'Neill
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King's College London

Changes in metabotropic glutamate receptor 1-8 gene expression in the rodent basal ganglia motor loop following lesion of the nigrostriatal tract

Neuropharmacology
2002-08 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: M J Messenger; L G Dawson; Susan Duty
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King's College London

The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration

CURRENT DRUG TARGETS CNS AND NEUROLOGICAL DISORDERS
2002-08 | Journal article | Author
SOURCE-WORK-ID:

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EID:

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Contributors: M J O'Neill; T K Murray; V Lakics; N P Visanji; Susan Duty
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King's College London

Changes in GABAB1A and GABAB2 receptor gene expression in the basal ganglia and thalamus of rats with a nigrostriatal tract lesion

British Journal of Pharmacology
2000 | Journal article | Author
SOURCE-WORK-ID:

dd9e38e2-2d2d-42f4-8c5c-4fbbaed82ff0

Contributors: T Johnston; P Jenner; Susan Duty
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King's College London

The 5HT(1B) receptor agonist, CP-93129, inhibits [H-3]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat

British Journal of Pharmacology
2000 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: A Chadha; C Sur; J Atack; Susan Duty
Source: check_circle
King's College London

The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat

British Journal of Pharmacology
2000 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: L Dawson; A Chadha; M Megalou; Susan Duty
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King's College London

Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus

Neuroscience
2000-11 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: A Chadha; L G Dawson; P G Jenner; Susan Duty
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King's College London

Changes in [H-3]zolpidem and [H-3]Ro 15-1788 binding in rat globus pallidus and substantia nigra pars reticulata following a nigrostriatal tract lesion

Brain Research
2000-04-17 | Journal article | Author
SOURCE-WORK-ID:

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WOSUID:

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EID:

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Contributors: A Chadha; O Howell; J R Atack; C Sur; Susan Duty
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King's College London

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)