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Works (21)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology
2024-12-27 | Journal article
Contributors: Raefa Abou Khouzam; Salem Chouaib; Mohammad Askandar Iqbal
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Phytocompounds Targeting Metabolic Reprogramming in Cancer: An Assessment of Role, Mechanisms, Pathways, and Therapeutic Relevance

Journal of Agricultural and Food Chemistry
2021-06-30 | Journal article
Contributors: Asifa Khan; Shumaila Siddiqui; Syed Akhtar Husain; Sybille Mazurek; Mohammad Askandar Iqbal
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Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer

Molecular Oncology
2021-05 | Journal article
Contributors: Mohammad Askandar Iqbal; Shumaila Siddiqui; Asad Ur Rehman; Farid Ahmad Siddiqui; Prithvi Singh; Bhupender Kumar; Daman Saluja
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Silibinin induces metabolic crisis in triple‐negative breast cancer cells by modulating EGFR‐MYC‐TXNIP axis: potential therapeutic implications

The FEBS Journal
2021-01 | Journal article
Contributors: Mohammad Askandar Iqbal; Shilpi Chattopadhyay; Farid Ahmad Siddiqui; Asad Ur Rehman; Shumaila Siddiqui; Gopinath Prakasam; Asifa Khan; Sarwat Sultana; Rameshwar NK Bamezai
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CBX2 and CBX7 antagonistically regulate metabolic reprogramming in breast cancer

bioRxiv
2020 | Other
EID:

2-s2.0-85098903336

Part of ISSN: 26928205
Contributors: Iqbal, M.A.; Siddiqui, S.; Rehman, A.U.; Siddiqui, F.A.; Singh, P.; Kumar, B.; Saluja, D.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

Cancer Cell International
2020 | Journal article
EID:

2-s2.0-85091377922

Part of ISSN: 14752867
Contributors: Rehman, A.U.; Iqbal, M.A.; Sattar, R.S.A.; Saikia, S.; Kashif, M.; Ali, W.M.; Medhi, S.; Saluja, S.S.; Husain, S.A.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

Molecular Aspects of Medicine
2019-12 | Journal article
Contributors: Mohammad Askandar Iqbal; Shweta Arora; Gopinath Prakasam; George A. Calin; Mansoor Ali Syed
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Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition

Scientific Reports
2018 | Journal article
EID:

2-s2.0-85047853847

Part of ISSN: 20452322
Contributors: Siddiqui, F.A.; Prakasam, G.; Chattopadhyay, S.; Rehman, A.U.; Padder, R.A.; Ansari, M.A.; Irshad, R.; Mangalhara, K.; Bamezai, R.N.K.; Husain, M. et al.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Posttranslational modifications of pyruvate kinase M2: Tweaks that benefit cancer

Frontiers in Oncology
2018 | Journal article
EID:

2-s2.0-85042109148

Part of ISSN: 2234943X
Contributors: Prakasam, G.; Iqbal, M.A.; Bamezai, R.N.K.; Mazurek, S.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Decreased expression of MGMT in correlation with aberrant DNA methylation in esophageal cancer patients from North India

Tumor Biology
2017 | Journal article
EID:

2-s2.0-85025133916

Part of ISSN: 14230380 10104283
Contributors: Ur Rehman, A.U.; Saikia, S.; Iqbal, M.A.; Ahmad, I.; Sadaf; Anees, A.; Aravinda, P.S.; Mishra, P.K.; Hedau, S.; Saluja, S.S. et al.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Pyruvate kinase M knockdown–induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival

Journal of Biological Chemistry
2017 | Journal article
EID:

2-s2.0-85029594127

Part of ISSN: 1083351X 00219258
Contributors: Prakasam, G.; Singh, R.K.; Iqbal, M.A.; Saini, S.K.; Tiku, A.B.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

ERK2-pyruvate kinase axis permits phorbol 12-myristate 13-acetate-induced megakaryocyte differentiation in K562 cells

Journal of Biological Chemistry
2015 | Journal article
EID:

2-s2.0-84942362037

Part of ISSN: 1083351X 00219258
Contributors: Chaman, N.; Iqbal, M.A.; Siddiqui, F.A.; Gopinath, P.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Pyruvate kinase M2: A metabolic tuner

Tumor Cell Metabolism: Pathways, Regulation and Biology
2015 | Book chapter
EID:

2-s2.0-84948738408

Contributors: Gupta, V.; Iqbal, M.A.; Kumar, B.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Resveratrol inhibits TIGAR to promote ROS induced apoptosis and autophagy

Biochimie
2015 | Journal article
EID:

2-s2.0-84938305715

Part of ISSN: 61831638 03009084
Contributors: Kumar, B.; Iqbal, M.A.; Singh, R.K.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Interplay between epigenetics & cancer metabolism

Current Pharmaceutical Design
2014 | Journal article
EID:

2-s2.0-84903744836

Part of ISSN: 18734286 13816128
Contributors: Gupta, V.; Gopinath, P.; Iqbal, M.A.; Mazurek, S.; Wellen, K.E.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner

Journal of Biological Chemistry
2014 | Journal article
EID:

2-s2.0-84896942604

Part of ISSN: 1083351X 00219258
Contributors: Iqbal, M.A.; Siddiqui, F.A.; Chaman, N.; Gupta, V.; Kumar, B.; Gopinath, P.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Pyruvate kinase M2 and cancer: An updated assessment

FEBS Letters
2014 | Journal article
EID:

2-s2.0-84905097406

Part of ISSN: 18733468 00145793
Contributors: Iqbal, M.A.; Gupta, V.; Gopinath, P.; Mazurek, S.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

Molecular Cancer
2013 | Journal article
EID:

2-s2.0-84880000375

Part of ISSN: 14764598
Contributors: Iqbal, M.A.; Siddiqui, F.A.; Gupta, V.; Chattopadhyay, S.; Gopinath, P.; Kumar, B.; Manvati, S.; Chaman, N.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of Mammalian target of Rapamycin

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84860499082

Part of ISSN: 19326203
Contributors: Iqbal, M.A.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Dominant negative mutations affect oligomerization of human pyruvate kinase M<inf>2</inf> isozyme and promote cellular growth and polyploidy

Journal of Biological Chemistry
2010 | Journal article
EID:

2-s2.0-77952776777

Part of ISSN: 00219258 1083351X
Contributors: Gupta, V.; Kalaiarasan, P.; Faheem, M.; Singh, N.; Iqbal, M.A.; Bamezai, R.N.K.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Methyl cyanide induces α to β transition and aggregation at high concentrations in e-state of human serum albumin

Biochemistry (Moscow)
2010 | Journal article
EID:

2-s2.0-77950688413

Part of ISSN: 00062979 16083040
Contributors: Sen, P.; Iqbal, M.A.; Fatima, S.; Khan, R.H.
Source: Self-asserted source
Mohammad Askandar Iqbal via Scopus - Elsevier

Peer review (5 reviews for 4 publications/grants)

Review activity for ACS omega. (2)
Review activity for Biochimica et biophysica acta. (1)
Review activity for Cell death and disease. (1)
Review activity for Journal of proteome research. (1)