Personal information

Other IDs

GND: 1211701999
Scopus Author ID: 57195809145
ResearcherID: ACL-1875-2022

Keywords

Liquid Biopsy, Metastatic breast cancer

Countries

Germany

Activities

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Employment (1)

Essen University Hospital: Essen, DE

PostDoctoral Researcher (Department of Gynecology and Obstetrics)
Employment
Source: Self-asserted source
Corinna Keup

Professional activities (3)

EFLM: European Federation of clinical chemistry and laboratory medicine: Milano, IT

2024-01-01 to present
Membership
Source: Self-asserted source
Corinna Keup

DGKL: German Society of Clinical Chemistry and Laboratory Medicine: Bonn, DE

2022-07 to present
Membership
Source: Self-asserted source
Corinna Keup

AACR: American Association for Cancer Research: Philadelphia, US

2017-01 to present | Associate Member
Membership
Source: Self-asserted source
Corinna Keup

Funding (1)

Multimodal liquid biopsy approach for the identification of predictive biomarkers for CDK4/6 inhibitor therapy in patients with breast cancer

2022-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
URL: https://app.dimensions.ai/details/grant/grant.12927253
GRANT_NUMBER: 493185725
Source: Self-asserted source
Corinna Keup via DimensionsWizard

Works (33)

Ratios of monocytes and neutrophils to lymphocytes in the blood predict benefit of CDK4/6 inhibitor treatment in metastatic breast cancer

Scientific Reports
2023-12-02 | Journal article
DOI: 10.1038/s41598-023-47874-3
Part of ISSN: 2045-2322
Contributors: Stefanos Ioannis Moukas; Sabine Kasimir-Bauer; Mitra Tewes; Hans-Christian Kolberg; Oliver Hoffmann; Rainer Kimmig; Corinna Keup
Source: Self-asserted source
Corinna Keup

The Diversity of Liquid Biopsies and Their Potential in Breast Cancer Management

Cancers
2023-11-17 | Journal article
DOI: 10.3390/cancers15225463
Contributors: Corinna Keup; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Abstract 2140: DNA damage response in circulating tumor cells shows predictive value for metastatic breast cancer patients receiving CDK4/6 inhibitors

Cancer Research
2023-04-04 | Journal article
DOI: 10.1158/1538-7445.am2023-2140
Part of ISSN: 1538-7445
Contributors: Corinna Keup; Charlotte Gruber; Stefanos Ioannis Moukas; Mitra Tewes; Hans-Christian Kolberg; Rainer Kimmig; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup

Abstract P5-02-25: Transcriptional profiling of CTCs in metastatic breast cancer patients in the course of CDK4/6 inhibition

Cancer Research
2023-03-01 | Journal article
DOI: 10.1158/1538-7445.sabcs22-p5-02-25
Part of ISSN: 1538-7445
Contributors: Sabine Kasimir-Bauer; Charlotte Gruber; Stefanos Moukas; Mitra Tewes; Hans-Christian Kolberg; Rainer Kimmig; Corinna Keup
Source: Self-asserted source
Corinna Keup

Abstract P5-02-50: Do thymidine kinase 1 (TK1) plasma concentration and activity play a role in therapy management of metastatic breast cancer patients treated with CDK4/6 inhibitors?

Cancer Research
2023-03-01 | Journal article
DOI: 10.1158/1538-7445.sabcs22-p5-02-50
Part of ISSN: 1538-7445
Contributors: Stefanos Moukas; Merle Dohn; Rainer Kimmig; Mitra Tewes; Hans-Christian Kolberg; Sabine Kasimir-Bauer; Corinna Keup
Source: Self-asserted source
Corinna Keup

Multimodality in liquid biopsy: does a combination uncover insights undetectable in individual blood analytes?

Journal of Laboratory Medicine
2022-08-26 | Journal article
DOI: 10.1515/labmed-2022-0009
Contributors: Corinna Keup; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref

Can we predict the benefit of CDK4/6 inhibitor treatment using the ratios of neutrophils, monocytes and platelets to lymphocytes in peripheral blood of metastatic breast cancer patients?

Senologie - Zeitschrift für Mammadiagnostik und -therapie
2022-06 | Conference poster
DOI: 10.1055/s-0042-1748410
Part of ISSN: 1611-647X
Contributors: S.I. Moukas; S. Kasimir-Bauer; M. Tewes; H.-C. Kolberg; R. Kimmig; C. Keup
Source: Self-asserted source
Corinna Keup

Abstract 6256: Longitudinal transcriptional profiling of CTCs in metastatic breast cancer patients receiving CDK4/6 inhibitors to predict response

Cancer Research
2022-06-15 | Journal article
DOI: 10.1158/1538-7445.am2022-6256
Part of ISSN: 1538-7445
Contributors: Corinna Keup; Charlotte Gruber; Oliver Hoffmann; Rainer Kimmig; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup

Combinatorial Power of cfDNA, CTCs and EVs in Oncology

Diagnostics
2022-03-31 | Journal article
DOI: 10.3390/diagnostics12040870
Contributors: Corinna Keup; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
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Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer

Genome Medicine
2021-12 | Journal article
DOI: 10.1186/s13073-021-00902-1
Contributors: Corinna Keup; Vinay Suryaprakash; Siegfried Hauch; Markus Storbeck; Peter Hahn; Markus Sprenger-Haussels; Hans-Christian Kolberg; Mitra Tewes; Oliver Hoffmann; Rainer Kimmig et al.
Source: check_circle
Crossref

Abstract PS2-24: Dynamics of a multi-parametric liquid biopsy, including CTCs, EVs, and cfDNA, during therapy in metastatic breast cancer patients provide useful insights for therapy management

Cancer Research
2021-02-15 | Journal article
DOI: 10.1158/1538-7445.sabcs20-ps2-24
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Sabine Kasimir-Bauer; Markus Storbeck; Peter Hahn; Siegfried Hauch; Markus Sprenger-Haussels; Oliver Hoffmann; Rainer Kimmig; Corinna Keup
Source: Self-asserted source
Corinna Keup

Abstract PS6-60: A clustering and mutual information based analysis of the ELIMA study results: The additive value of multi-parametric liquid biopsies, including CTCs, EVs and cfDNA, in metastatic breast cancer

Cancer Research
2021-02-15 | Journal article
DOI: 10.1158/1538-7445.sabcs20-ps6-60
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Sabine Kasimir-Bauer; Vinay Suryaprakash; Markus Storbeck; Peter Hahn; Siegfried Hauch; Markus Sprenger-Haussels; Oliver Hoffmann; Rainer Kimmig; Corinna Keup
Source: Self-asserted source
Corinna Keup

Longitudinal Multi-Parametric Liquid Biopsy Approach Identifies Unique Features of Circulating Tumor Cell, Extracellular Vesicle, and Cell-Free DNA Characterization for Disease Monitoring in Metastatic Breast Cancer Patients

Cells
2021-01-21 | Journal article
DOI: 10.3390/cells10020212
Contributors: Corinna Keup; Vinay Suryaprakash; Markus Storbeck; Oliver Hoffmann; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Comprehensive molecular characterization of circulating tumor cells, extracellular vesicles and cell-free DNA as matched multi-parametric liquid biopsy for therapy management in metastatic breast cancer patients

2020 | Book
DOI: 10.17185/duepublico/70801
DNB: 1221960350
URN: urn:nbn:de:hbz:464-20201110-083641-9
Contributors: Corinna Keup; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup via Deutsche Nationalbibliothek (DNB)

Liquid Biopsies to Evaluate Immunogenicity of Gynecological/Breast Tumors: On the Way to Blood-Based Biomarkers for Immunotherapies

Breast Care
2020 | Journal article
DOI: 10.1159/000510509
Contributors: Corinna Keup; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Circulating Tumor Cells Expressing the Prostate Specific Membrane Antigen (PSMA) Indicate Worse Outcome in Primary, Non-Metastatic Triple-Negative Breast Cancer

Frontiers in Oncology
2020-09-03 | Journal article
DOI: 10.3389/fonc.2020.01658
Part of ISSN: 2234-943X
Source: Self-asserted source
Corinna Keup
grade
Preferred source (of 2)‎

Abstract 5366: Metastatic breast cancer subgroup specific mRNA profiles of circulating tumor cells and extracellular vesicles

Clinical Trials
2020-08-15 | Conference paper
DOI: 10.1158/1538-7445.am2020-5366
Source: Self-asserted source
Corinna Keup

Molecular characterization of circulating tumour cells identifies predictive markers for outcome in primary, triple‐negative breast cancer patients

Journal of Cellular and Molecular Medicine
2020-06-18 | Journal article
DOI: 10.1111/jcmm.15349
Part of ISSN: 1582-1838
Part of ISSN: 1582-4934
Source: Self-asserted source
Corinna Keup
grade
Preferred source (of 2)‎

Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer Patients

Cancers
2020-04-27 | Journal article
DOI: 10.3390/cancers12051084
Contributors: Corinna Keup; Markus Storbeck; Siegfried Hauch; Peter Hahn; Markus Sprenger-Haussels; Oliver Hoffmann; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Targeted deep sequencing revealed variants in cell-free DNA of hormone receptor-positive metastatic breast cancer patients

Cellular and Molecular Life Sciences
2020-02-28 | Journal article
DOI: 10.1007/s00018-019-03189-z
Contributors: Corinna Keup; Karim Benyaa; Siegfried Hauch; Markus Sprenger-Haussels; Mitra Tewes; Pawel Mach; Ann-Kathrin Bittner; Rainer Kimmig; Peter Hahn; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Abstract P4-01-11: Circulating tumor cells expressing the prostate specific membrane antigen PSMA indicate worse outcome in triple-negative breast cancer patients at primary diagnosis

Poster Session Abstracts
2020-02-15 | Conference paper
DOI: 10.1158/1538-7445.sabcs19-p4-01-11
Source: Self-asserted source
Corinna Keup

Abstract P5-01-14: The combined blood analysis of cell-free DNA and genomic DNA of circulating tumor cells reveals additive value in hormone receptor-positive, HER2-negative metastatic breast cancer patients

Poster Session Abstracts
2020-02-15 | Conference paper
DOI: 10.1158/1538-7445.sabcs19-p5-01-14
Source: Self-asserted source
Corinna Keup

Abstract 1369: Establishment of a workflow for analysis of mRNA and gDNA from circulating tumor cells, extracellular vesicles and cell-free DNA from the same blood sample to mirror the genomic and transcriptomic complexity in metastatic breast cancer patients

Clinical Research (Excluding Clinical Trials)
2019-07-01 | Conference paper
DOI: 10.1158/1538-7445.am2019-1369
Source: Self-asserted source
Corinna Keup

Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer

Cancers
2019-02-18 | Journal article
DOI: 10.3390/cancers11020238
Contributors: Corinna Keup; Markus Storbeck; Siegfried Hauch; Peter Hahn; Markus Sprenger-Haussels; Mitra Tewes; Pawel Mach; Oliver Hoffmann; Rainer Kimmig; Sabine Kasimir-Bauer
Source: check_circle
Crossref
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Abstract P4-01-10: The analysis of cell-free DNA and circulating tumor cells from one blood tube might empower treatment decisions in metastatic breast cancer patients

Poster Session Abstracts
2019-02-15 | Conference abstract
DOI: 10.1158/1538-7445.sabcs18-p4-01-10
Source: Self-asserted source
Corinna Keup

Targeted PCR-based deep sequencing of cfDNA with unique molecular indices by a customized QIAseq Targeted DNA Panel v1 (protocols.io.trfem3n)

protocols.io
2018-09-19 | Research protocol or technique
DOI: 10.17504/protocols.io.trfem3n
Source: Self-asserted source
Corinna Keup
grade
Preferred source (of 4)‎

Abstract 3650: Use of unique molecular identifiers to gain insight about the true positive mutations in cfDNA of breast cancer patients for implementation of personalized treatment

Cancer Research
2018-07-01 | Journal article
DOI: 10.1158/1538-7445.am2018-3650
Part of ISSN: 0008-5472
Contributors: Corinna Keup; Karim Benyaa; Peter Hahn; Siegfried Hauch; Pawel Mach; Mitra Tewes; Hans-Christian Kolberg; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup via Crossref Metadata Search

Molecular characterization of circulating tumor cells identifies predictive markers for outcome in triple-negative breast cancer patients

Information und Programm: www.senologiekongress.de
2018-05 | Conference abstract
DOI: 10.1055/s-0038-1651689
Source: Self-asserted source
Corinna Keup

RNA Profiles of Circulating Tumor Cells and Extracellular Vesicles for Therapy Stratification of Metastatic Breast Cancer Patients

Clinical Chemistry
2018-05 | Journal article
DOI: 10.1373/clinchem.2017.283531
Part of ISSN: 0009-9147
Contributors: Corinna Keup; Pawel Mach; Bahriye Aktas; Mitra Tewes; Hans-Christian Kolberg; Siegfried Hauch; Markus Sprenger-Haussels; Rainer Kimmig; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup via Crossref Metadata Search
grade
Preferred source (of 2)‎

Abstract P2-01-06: Similarities and differences in RNA profiles of circulating tumor cells in breast cancer subtypes: Do we have therapeutic options?

Cancer Research
2018-02 | Journal article
DOI: 10.1158/1538-7445.sabcs17-p2-01-06
Part of ISSN: 0008-5472
Contributors: A-K Bittner; O Hoffmann; C Keup; S Hauch; R Kimmig; S Kasimir-Bauer
Source: Self-asserted source
Corinna Keup via Crossref Metadata Search

Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state

2017 | Journal article
DOI: 10.18419/opus-9240
DNB: 1141683601
URN: urn:nbn:de:bsz:93-opus-ds-92571
Contributors: Rebekka Mauser; Goran Kungulovski; Corinna Keup; Richard Reinhardt; Albert Jeltsch
Source: Self-asserted source
Corinna Keup via Deutsche Nationalbibliothek (DNB)

Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state

Epigenetics & Chromatin
2017-09 | Journal article
DOI: 10.1186/s13072-017-0153-1
Part of ISSN: 1756-8935
Contributors: Rebekka Mauser; Goran Kungulovski; Corinna Keup; Richard Reinhardt; Albert Jeltsch
Source: Self-asserted source
Corinna Keup via Crossref Metadata Search
grade
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Abstract 3777: RNA profiles of circulating tumor cells and extracellular vesicles for therapy stratification of metastatic breast cancer patients

Cancer Research
2017-07-01 | Journal article
DOI: 10.1158/1538-7445.am2017-3777
Part of ISSN: 0008-5472
Contributors: Corinna Keup; Siegfried Hauch; Linda Plappert; Markus Sprenger-Haussels; Pawel Mach; Mitra Tewes; Bahriye Aktas; Hans-Christian Kolberg; Rainer Kimmig; Sabine Kasimir-Bauer
Source: Self-asserted source
Corinna Keup via Crossref Metadata Search

Peer review (4 reviews for 3 publications/grants)

Review activity for Annals of translational medicine. (1)
Review activity for Cancers. (1)
Review activity for Diagnostics. (2)
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