Personal information

United States

Activities

Employment (1)

Pacific Northwest Research Institute: SEATTLE, WA, US

2019-03-15 to present | Senior Investigator, Director of Educational Outreach
Employment
Source: Self-asserted source
Aimee Dudley

Funding (3)

High resolution genetic dissection of complex and quantitative traits in yeast

2016-07-01 to 2020-05-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: 1R01GM117119-01
Source: Self-asserted source
Aimee Dudley via DimensionsWizard

Computation and functional significance of multi-phenotype genetic interaction ma

2010-09-01 to 2016-08-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: 5R01GM089978-05
Source: Self-asserted source
Aimee Dudley via DimensionsWizard

Temporal and spatial effects on expression and function

2003-08-15 to 2009-10-31 | Grant
National Human Genome Research Institute (Bethesda, US)
GRANT_NUMBER: 5K22HG002908-05
Source: Self-asserted source
Aimee Dudley via DimensionsWizard

Works (40)

Spatiotemporal patterns of gene expression during development of a complex colony morphology

PLOS ONE
2024-12-05 | Journal article
Contributors: Gareth A. Cromie; Hector Escriva; Zhihao Tan; Michelle Hays; Amy Sirr; Aimée M. Dudley
Source: check_circle
Crossref

Onwards! Open science and the (PLOS) genetics community

PLOS Genetics
2024-11-28 | Journal article
Contributors: Aimée M. Dudley; Monica P. Colaiácovo; Anne Goriely; Julia Squarr
Source: check_circle
Crossref

Spatiotemporal Patterns of Gene Expression During Development of a Complex Colony Morphology

2024-09-16 | Preprint
Contributors: Gareth A. Cromie; Zhihao Tan; Michelle Hays; Amy Sirr; Aimée M. Dudley
Source: check_circle
Crossref

Constructing and interpreting a large-scale variant effect map for an ultrarare disease gene: Comprehensive prediction of the functional impact of PSAT1 genotypes

PLOS Genetics
2023-10-09 | Journal article
Contributors: Michael J. Xie; Brenda J. Andrews; Gareth A. Cromie; Katherine Owens; Martin S. Timour; Michelle Tang; J. Nathan Kutz; Ayman W. El-Hattab; Richard N. McLaughlin; Aimée M. Dudley
Source: check_circle
Crossref

Predicting the functional effect of compound heterozygous genotypes from large scale variant effect maps

2023-01-15 | Preprint
Contributors: Michael J. Xie; Gareth A. Cromie; Katherine Owens; Martin S. Timour; Michelle Tang; J. Nathan Kutz; Ayman W. El-Hattab; Richard N. McLaughlin, Jr.; Aimée M. Dudley
Source: check_circle
Crossref

A method for quantifying sporulation efficiency and isolating meiotic progeny in non‐GMO strains of Saccharomyces cerevisiae

Yeast
2022-06 | Journal article
Contributors: Amy Sirr; Martin S. Timour; Gareth A. Cromie; Michelle Tang; Aimée M. Dudley
Source: check_circle
Crossref

A yeast‐based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1

Journal of Inherited Metabolic Disease
2020-07 | Journal article
Contributors: Amy Sirr; Russell S. Lo; Gareth A. Cromie; Adrian C. Scott; Julee Ashmead; Mirutse Heyesus; Aimée M. Dudley
Source: check_circle
Crossref

Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies

2019-03-12 | Other
Contributors: Nikita A. Sakhanenko; Gareth A. Cromie; Aimée M. Dudley; David J. Galas
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

A polyploid admixed origin of beer yeasts derived from European and Asian wine populations

PLOS Biology
2019-03-05 | Journal article
Contributors: Justin C. Fay; Jeff Gore; Ping Liu; Giang T. Ong; Maitreya J. Dunham; Gareth A. Cromie; Eric W. Jeffery; Catherine L. Ludlow; Aimée M. Dudley
Source: check_circle
Crossref

Natural Variation in SER1 and ENA6 Underlie Condition-Specific Growth Defects in Saccharomyces cerevisiae

G3: Genes|Genomes|Genetics
2018-01 | Journal article
Contributors: Amy Sirr; Adrian C. Scott; Gareth A. Cromie; Catherine L. Ludlow; Vida Ahyong; Trey S. Morgan; Teresa Gilbert; Aimée M. Dudley
Source: check_circle
Crossref

Exposure to the oral host niche yields rapid phenotypic and genotypic diversification in Candida albicans

2018-01-25 | Other
Contributors: A. Forche; G. Cromie; A.C. Gerstein; N. V. Solis; Z. Pisithkul; W. Srifa; E. Jeffery; S.G. Filler; A.M. Dudley; J. Berman
Source: check_circle
Crossref

Meeting Report on Experimental Approaches to Evolution and Ecology Using Yeast and Other Model Systems

G3: Genes|Genomes|Genetics
2017-10 | Journal article
Contributors: Daniel F. Jarosz; Aimée M. Dudley
Source: check_circle
Crossref

Transcriptional Profiling of Biofilm Regulators Identified by an Overexpression Screen in Saccharomyces cerevisiae

G3: Genes|Genomes|Genetics
2017-08 | Journal article
Contributors: Gareth A. Cromie; Zhihao Tan; Michelle Hays; Amy Sirr; Eric W. Jeffery; Aimée M. Dudley
Source: check_circle
Crossref

Dissecting Gene Expression Changes Accompanying a Ploidy-Based Phenotypic Switch

G3: Genes|Genomes|Genetics
2017-01 | Journal article
Contributors: Gareth A. Cromie; Zhihao Tan; Michelle Hays; Eric W. Jeffery; Aimée M. Dudley
Source: check_circle
Crossref

Independent Origins of Yeast Associated with Coffee and Cacao Fermentation.

2016-04 | Journal article
Contributors: Ludlow CL; Cromie GA; Garmendia-Torres C; Sirr A; Hays M; Field C; Jeffery EW; Fay JC; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly.

2015-11 | Journal article
Contributors: Cary GA; Vinh DB; May P; Kuestner R; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central
grade
Preferred source (of 2)‎

Aneuploidy: Tolerating Tolerance.

2015-08 | Journal article
Contributors: Cromie GA; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans.

2015-07 | Journal article
Contributors: Hickman MA; Paulson C; Dudley A; Berman J
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

BEST: barcode enabled sequencing of tetrads.

2014 | Journal article
DOI:

10.3791/51401

PMID:

24836713

PMC:

PMC4172027

Contributors: Scott AC; Ludlow CL; Cromie GA; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Unidirectional P-body transport during the yeast cell cycle.

2014 | Journal article
DOI:

10.1371/journal.pone.0099428

PMID:

24918601

PMC:

PMC4053424

Contributors: Garmendia-Torres C; Skupin A; Michael SA; Ruusuvuori P; Kuwada NJ; Falconnet D; Cary GA; Hansen C; Wiggins PA; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Allelic Variation, Aneuploidy and Non-Genetic Mechanisms Suppress a Monogenic Trait in Yeast.

2014-11 | Journal article
DOI:

10.1534/genetics.114.170563

PMID:

25398792

Contributors: Sirr A; Cromie GA; Jeffery EW; Gilbert TL; Ludlow CL; Scott AC; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Identification and characterization of a drug-sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae.

2014-05 | Journal article
DOI:

10.1002/yea.3007

PMID:

24610064

Contributors: Cary GA; Yoon SH; Torres CG; Wang K; Hays M; Ludlow C; Goodlett DR; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Quantitative analysis of colony morphology in yeast.

2014-01 | Journal article
DOI:

10.2144/000114123

PMID:

24447135

PMC:

PMC3996921

Contributors: Ruusuvuori P; Lin J; Scott AC; Tan Z; Sorsa S; Kallio A; Nykter M; Yli-Harja O; Shmulevich I; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

POMO--Plotting Omics analysis results for Multiple Organisms.

2013 | Journal article
DOI:

10.1186/1471-2164-14-918

PMID:

24365393

PMC:

PMC3880012

Contributors: Lin J; Kreisberg R; Kallio A; Dudley AM; Nykter M; Shmulevich I; May P; Autio R
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Genomic sequence diversity and population structure of Saccharomyces cerevisiae assessed by RAD-seq.

2013-12 | Journal article
DOI:

10.1534/g3.113.007492

PMID:

24122055

PMC:

PMC3852379

Contributors: Cromie GA; Hyma KE; Ludlow CL; Garmendia-Torres C; Gilbert TL; May P; Huang AA; Dudley AM; Fay JC
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Aneuploidy underlies a multicellular phenotypic switch.

2013-07 | Journal article
DOI:

10.1073/pnas.1301047110

PMID:

23812752

PMC:

PMC3725063

Contributors: Tan Z; Hays M; Cromie GA; Jeffery EW; Scott AC; Ahyong V; Sirr A; Skupin A; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

High-throughput tetrad analysis.

2013-07 | Journal article
Contributors: Ludlow CL; Scott AC; Cromie GA; Jeffery EW; Sirr A; May P; Lin J; Gilbert TL; Hays M; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Genetics. Systems genetics.

2011-02 | Journal article
DOI:

10.1126/science.1203869

PMID:

21350153

PMC:

PMC4042627

Contributors: Nadeau JH; Dudley AM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images.

2010 | Journal article
DOI:

10.1186/1471-2105-11-248

PMID:

20465797

PMC:

PMC3098061

Contributors: Ruusuvuori P; Aijö T; Chowdhury S; Garmendia-Torres C; Selinummi J; Birbaumer M; Dudley AM; Pelkmans L; Yli-Harja O
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Surface plasmon resonance biosensor for rapid label-free detection of microribonucleic acid at subfemtomole level.

2010-12 | Journal article
DOI:

10.1021/ac102131s

PMID:

21090631

PMC:

PMC3021551

Contributors: Sípová H; Zhang S; Dudley AM; Galas D; Wang K; Homola J
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Learning a prior on regulatory potential from eQTL data.

2009-01 | Journal article
DOI:

10.1371/journal.pgen.1000358

PMID:

19180192

PMC:

PMC2627940

Contributors: Lee SI; Dudley AM; Drubin D; Silver PA; Krogan NJ; Pe'er D; Koller D
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.

2008 | Journal article
DOI:

10.1186/gb-2008-9-9-r140

PMID:

18808699

PMC:

PMC2592718

Contributors: Snitkin ES; Dudley AM; Janse DM; Wong K; Church GM; Segrè D
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification.

2006-09 | Journal article
DOI:

10.1073/pnas.0601852103

PMID:

16968785

PMC:

PMC1599912

Contributors: Lee SI; Pe'er D; Dudley AM; Church GM; Koller D
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

A global view of pleiotropy and phenotypically derived gene function in yeast.

2005 | Journal article
DOI:

10.1038/msb4100004

PMID:

16729036

PMC:

PMC1681449

Contributors: Dudley AM; Janse DM; Tanay A; Shamir R; Church GM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Predicting phenotype from patterns of annotation.

2003 | Journal article
DOI:

10.1093/bioinformatics/btg1024

PMID:

12855456

Contributors: King OD; Lee JC; Dudley AM; Janse DM; Church GM; Roth FP
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range.

2002-05 | Journal article
DOI:

10.1073/pnas.112683499

PMID:

12032321

PMC:

PMC124281

Contributors: Dudley AM; Aach J; Steffen MA; Church GM
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo.

1999-11 | Journal article
DOI:

10.1101/gad.13.22.2940

PMID:

10580001

PMC:

PMC317152

Contributors: Dudley AM; Rougeulle C; Winston F
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Specific components of the SAGA complex are required for Gcn4- and Gcr1-mediated activation of the his4-912delta promoter in Saccharomyces cerevisiae.

1999-04 | Journal article
PMID:

10101163

PMC:

PMC1460567

Contributors: Dudley AM; Gansheroff LJ; Winston F
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Identification and analysis of Mot3, a zinc finger protein that binds to the retrotransposon Ty long terminal repeat (delta) in Saccharomyces cerevisiae.

1998-04 | Journal article
PMID:

9528759

PMC:

PMC121417

Contributors: Madison JM; Dudley AM; Winston F
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

T7 RNA polymerase-dependent expression of COXII in yeast mitochondria.

1994-07 | Journal article
PMID:

8007968

PMC:

PMC358837

Contributors: Pinkham JL; Dudley AM; Mason TL
Source: Self-asserted source
Aimee Dudley via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for PLOS genetics. (1)