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University of Innsbruck: Innsbruck, AT

2013-01-01 to present (Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Petronel Tuluc

Works (44)

Excitation-secretion coupling in chromaffin cells of the adrenal gland: Where does calcium come from?

Pflugers Archiv European Journal of Physiology
2024 | Journal article
EID:

2-s2.0-85174270911

Part of ISSN: 14322013 00316768
Contributors: Tuluc, P.; Carbone, E.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings

Science Advances
2024-11 | Journal article
Contributors: Pedro J. del Rivero Morfin; Diego Scala Chavez; Srinidhi Jayaraman; Lin Yang; Stefanie M. Geisler; Audrey L. Kochiss; Petronel Tuluc; Henry M. Colecraft; Steven O. Marx; X. Shawn Liu et al.
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Deletion of the α2δ‐1 calcium channel subunit increases excitability of mouse chromaffin cells

The Journal of Physiology
2024-08 | Journal article
Contributors: Stefanie M. Geisler; Matteo M. Ottaviani; Noelia Jacobo‐Piqueras; Tamara Theiner; Vincenzo Mastrolia; Laura Guarina; Karl Ebner; Gerald J. Obermair; Emilio Carbone; Petronel Tuluc
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CaV1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling

Nature Communications
2024-08-28 | Journal article
Contributors: Simone Pelizzari; Martin C. Heiss; Monica L. Fernández-Quintero; Yousra El Ghaleb; Klaus R. Liedl; Petronel Tuluc; Marta Campiglio; Bernhard E. Flucher
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Molecular mechanism responsible for sex differences in electrical activity of mouse pancreatic β-cells

JCI Insight
2024-02-15 | Journal article
Contributors: Noelia Jacobo-Piqueras; Tamara Theiner; Stefanie M. Geisler; Petronel Tuluc
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The human channel gating–modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome–like phenotype in mice

JCI Insight
2023 | Journal article
EID:

2-s2.0-85175098816

Part of ISSN: 23793708
Contributors: Ortner, N.J.; Sah, A.; Paradiso, E.; Shin, J.; Stojanovic, S.; Hammer, N.; Haritonova, M.; Hofer, N.T.; Marcantoni, A.; Guarina, L. et al.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Calcium current modulation by the γ<sub>1</sub> subunit depends on alternative splicing of Ca<sub>V</sub>1.1

Journal of General Physiology
2022 | Journal article
EID:

2-s2.0-85127298642

Part of ISSN: 15407748 00221295
Contributors: El Ghaleb, Y.; Ortner, N.J.; Posch, W.; Fernández-Quintero, M.L.; Tuinte, W.E.; Monteleone, S.; Draheim, H.J.; Liedl, K.R.; Wilflingseder, D.; Striessnig, J. et al.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

STAC3 determines the slow activation kinetics of Ca<sub>V</sub>1.1 currents and inhibits its voltage-dependent inactivation

Journal of Cellular Physiology
2022 | Journal article
EID:

2-s2.0-85138647669

Part of ISSN: 10974652 00219541
Contributors: Tuinte, W.E.; Török, E.; Mahlknecht, I.; Tuluc, P.; Flucher, B.E.; Campiglio, M.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders

Brain
2021 | Journal article
EID:

2-s2.0-85102920109

Part of ISSN: 14602156 00068950
Contributors: El Ghaleb, Y.; Schneeberger, P.E.; Fernández-Quintero, M.L.; Geisler, S.M.; Pelizzari, S.; Polstra, A.M.; Van Hagen, J.M.; Denecke, J.; Campiglio, M.; Liedl, K.R. et al.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Calcium current modulation by the γ<sub>1</sub> subunit depends on alternative splicing of Ca<sub>V</sub>1.1

bioRxiv
2021 | Other
EID:

2-s2.0-85121501475

Part of ISSN: 26928205
Contributors: Ghaleb, Y.E.; Ortner, N.J.; Posch, W.; Fernández-Quintero, M.L.; Tuinte, W.E.; Monteleone, S.; Draheim, H.J.; Liedl, K.R.; Wilflingseder, D.; Striessnig, J. et al.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Role of high voltage-gated ca<sup>2+</sup> channel subunits in pancreatic β-cell insulin release. From structure to function

Cells
2021 | Journal article
EID:

2-s2.0-85115042574

Part of ISSN: 20734409
Contributors: Tuluc, P.; Theiner, T.; Jacobo-Piqueras, N.; Geisler, S.M.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Ion-pair interactions between voltage-sensing domain IV and pore domain I regulate CaV1.1 gating

Biophysical Journal
2021-10 | Journal article
Contributors: Yousra El Ghaleb; Monica L. Fernández-Quintero; Stefania Monteleone; Petronel Tuluc; Marta Campiglio; Klaus R. Liedl; Bernhard E. Flucher
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Exciting leak: Na+ background current makes chromaffin cells burst

The Journal of Physiology
2021-03 | Journal article
Contributors: Petronel Tuluc
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Structural determinants of voltage-gating properties in calcium channels

eLife
2021-03-30 | Journal article
Contributors: Monica L Fernández-Quintero; Yousra El Ghaleb; Petronel Tuluc; Marta Campiglio; Klaus R Liedl; Bernhard E Flucher
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Stabilization of negative activation voltages of Cav1.3 L-Type Ca2+-channels by alternative splicing

Channels
2021-01-01 | Journal article
Contributors: Nadja T. Hofer; Alexandra Pinggera; Yuliia V. Nikonishyna; Petronel Tuluc; Eva M. Fritz; Gerald J. Obermair; Jörg Striessnig
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Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder

Molecular Autism
2020 | Journal article
EID:

2-s2.0-85077757890

Part of ISSN: 20402392
Contributors: Hofer, N.T.; Tuluc, P.; Ortner, N.J.; Nikonishyna, Y.V.; Fernándes-Quintero, M.L.; Liedl, K.R.; Flucher, B.E.; Cox, H.; Striessnig, J.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2‐neo mouse rescued by L‐type calcium channel blockers

The Journal of Physiology
2019-03 | Journal article
Contributors: Chiara Calorio; Daniela Gavello; Laura Guarina; Chiara Salio; Marco Sassoè‐Pognetto; Chiara Riganti; Federico Tommaso Bianchi; Nadja T. Hofer; Petronel Tuluc; Gerald J. Obermair et al.
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STAC proteins associate to the IQ domain of Ca V 1.2 and inhibit calcium-dependent inactivation

Proceedings of the National Academy of Sciences
2018-02-06 | Journal article
Contributors: Marta Campiglio; Pierre Costé de Bagneaux; Nadine J. Ortner; Petronel Tuluc; Filip Van Petegem; Bernhard E. Flucher
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Gating defects of disease-causing de novo mutations in Cav1.3 Ca2+ channels

Channels
2018-01-01 | Journal article
Contributors: Alexandra Pinggera; Giulia Negro; Petronel Tuluc; Morris J. Brown; Andreas Lieb; Jörg Striessnig
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Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels

Channels
2018-01-01 | Journal article
Contributors: Pierre Costé de Bagneaux; Marta Campiglio; Bruno Benedetti; Petronel Tuluc; Bernhard E. Flucher
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Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

Diabetes
2017 | Journal article
EID:

2-s2.0-85019633638

Part of ISSN: 1939327X 00121797
Contributors: Mastrolia, V.; Flucher, S.M.; Obermair, G.J.; Drach, M.; Hofer, H.; Renström, E.; Schwartz, A.; Striessnig, J.; Flucher, B.E.; Tuluc, P.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Mechanisms Responsible for ω-Pore Currents in Ca<sub>v</sub> Calcium Channel Voltage-Sensing Domains

Biophysical Journal
2017 | Journal article
EID:

2-s2.0-85030717945

Part of ISSN: 15420086 00063495
Contributors: Monteleone, S.; Lieb, A.; Pinggera, A.; Negro, G.; Fuchs, J.E.; Hofer, F.; Striessnig, J.; Tuluc, P.; Liedl, K.R.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease

The Journal of Neuroscience
2017-07-12 | Journal article
Contributors: Nadine J. Ortner; Gabriella Bock; Antonios Dougalis; Maria Kharitonova; Johanna Duda; Simon Hess; Petronel Tuluc; Thomas Pomberger; Nadia Stefanova; Florian Pitterl et al.
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How and why are calcium currents curtailed in the skeletal muscle voltage‐gated calcium channels?

The Journal of Physiology
2017-03 | Journal article
Contributors: Bernhard E. Flucher; Petronel Tuluc
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Restricting calcium currents is required for correct fiber type specification in skeletal muscle

Development (Cambridge)
2016 | Journal article
EID:

2-s2.0-84964893839

Part of ISSN: 14779129 09501991
Contributors: Sultana, N.; Dienes, B.; Benedetti, A.; Tuluc, P.; Szentesi, P.; Sztretye, M.; Rainer, J.; Hess, M.W.; Schwarzer, C.; Obermair, G.J. et al.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in Ca<sub>v</sub>1.1 calcium channels

Journal of General Physiology
2016 | Journal article
EID:

2-s2.0-84973562842

Part of ISSN: 15407748 00221295
Contributors: Tuluc, P.; Benedetti, B.; Costé de Bagneaux, P.; Grabner, M.; Flucher, B.E.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Molecular Interactions in the Voltage Sensor Controlling Gating Properties of CaV Calcium Channels.

2015-12 | Journal article
Contributors: Tuluc P; Yarov-Yarovoy V; Benedetti B; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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CACNA1D De Novo Mutations in Autism Spectrum Disorders Activate Cav1.3 L-Type Calcium Channels

Biological Psychiatry
2015-05 | Journal article
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Physiological and pharmacological modulation of the embryonic skeletal muscle calcium channel splice variant CaV1.1e.

2015-03 | Journal article
Contributors: Benedetti B; Tuluc P; Mastrolia V; Dlaska C; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

2014 | Journal article
Contributors: Ortner NJ; Bock G; Vandael DH; Mauersberger R; Draheim HJ; Gust R; Carbone E; Tuluc P; Striessnig J
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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L-type Ca(2+) channels in heart and brain.

2014-03 | Journal article
Contributors: Striessnig J; Pinggera A; Kaur G; Bock G; Tuluc P
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Petronel Tuluc via Europe PubMed Central
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Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

2013-09 | Journal article
Contributors: Azizan EA; Poulsen H; Tuluc P; Zhou J; Clausen MV; Lieb A; Maniero C; Garg S; Bochukova EG; Zhao W et al.
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Stable incorporation versus dynamic exchange of β subunits in a native Ca2+ channel complex.

2013-05 | Journal article
Contributors: Campiglio M; Di Biase V; Tuluc P; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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A new L-type calcium channel isoform required for normal patterning of the developing neuromuscular junction.

2011 | Journal article
Contributors: Flucher BE; Tuluc P
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Divergent biophysical properties, gating mechanisms, and possible functions of the two skeletal muscle Ca(V)1.1 calcium channel splice variants.

2011-12 | Journal article
Contributors: Tuluc P; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Surface traffic of dendritic CaV1.2 calcium channels in hippocampal neurons.

2011-09 | Journal article
Contributors: Di Biase V; Tuluc P; Campiglio M; Obermair GJ; Heine M; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the Cavalpha1S-subunit.

2010-12 | Journal article
Contributors: Pirone A; Schredelseker J; Tuluc P; Gravino E; Fortunato G; Flucher BE; Carsana A; Salvatore F; Grabner M
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.

2009-01 | Journal article
Contributors: Tuluc P; Molenda N; Schlick B; Obermair GJ; Flucher BE; Jurkat-Rott K
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Auxiliary Ca(2+) channel subunits: lessons learned from muscle.

2008-06 | Journal article
Contributors: Obermair GJ; Tuluc P; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel alpha2delta-1 subunit in cardiac excitation-contraction coupling.

2007-06 | Journal article
Contributors: Tuluc P; Kern G; Obermair GJ; Flucher BE
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Petronel Tuluc via Europe PubMed Central
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The role of auxiliary dihydropyridine receptor subunits in muscle.

2005 | Journal article
Contributors: Flucher BE; Obermair GJ; Tuluc P; Schredelseker J; Kern G; Grabner M
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Petronel Tuluc via Europe PubMed Central
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The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling.

2005-01 | Journal article
Contributors: Obermair GJ; Kugler G; Baumgartner S; Tuluc P; Grabner M; Flucher BE
Source: Self-asserted source
Petronel Tuluc via Europe PubMed Central
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Composite plasma-polymerized organosiloxane-based material for hydrocarbon vapor selectivity

Journal of Membrane Science
2004 | Journal article
EID:

2-s2.0-0742306471

Part of ISSN: 03767388
Contributors: Rouessac, V.; Tuluc, P.; Durand, J.
Source: Self-asserted source
Petronel Tuluc via Scopus - Elsevier

Composite plasma-polymerized organosiloxane-based material for hydrocarbon vapor selectivity

Journal of Membrane Science
2004 | Journal article
Source: Self-asserted source
Petronel Tuluc

Peer review (5 reviews for 3 publications/grants)

Review activity for Biochimica et biophysica acta. (2)
Review activity for Pflügers Archiv. (2)
Review activity for Translational psychiatry. (1)