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Employment (1)

Japanese Foundation For Cancer Research: Tokyo, JP

2020-04 to present | Clinical Research Fellow (Cancer Cell Diversity Project, NEXT-Ganken Program)
Employment
Source: Self-asserted source
Kohei Kumegawa

Education and qualifications (2)

Tohoku University: Sendai, JP

2020-10-01 to 2023-09-25 | Doctor of Philosophy in Medicine (Ph.D.) (Graduate School of Medicine)
Education
Source: Self-asserted source
Kohei Kumegawa

Sapporo Medical University: Sapporo, JP

2010-04-01 to 2016-03-31 | Doctor of Medicine (M.D.) (School of Medicine)
Education
Source: Self-asserted source
Kohei Kumegawa

Works (17)

Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer

npj Precision Oncology
2024-10-03 | Journal article
DOI: 10.1038/s41698-024-00723-6
Contributors: Kazutaka Otsuji; Yoko Takahashi; Tomo Osako; Takayuki Kobayashi; Toshimi Takano; Sumito Saeki; Liying Yang; Satoko Baba; Kohei Kumegawa; Hiromu Suzuki et al.
Source: check_circle
Crossref

Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression

Developmental Cell
2024-06 | Journal article
DOI: 10.1016/j.devcel.2024.05.013
Part of ISSN: 1534-5807
Contributors: Ryo Shiraishi; Gabriele Cancila; Kohei Kumegawa; Jacob Torrejon; Irene Basili; Flavia Bernardi; Patricia Benites Goncalves da Silva; Wanchen Wang; Owen Chapman; Liying Yang et al.
Source: Self-asserted source
Kohei Kumegawa

Identification of lineage-specific epigenetic regulators FOXA1 and GRHL2 through chromatin accessibility profiling in breast cancer cell lines

Cancer Gene Therapy
2024-05 | Journal article
DOI: 10.1038/s41417-024-00745-z
Contributors: Liying Yang; Kohei Kumegawa; Sumito Saeki; Tomoyoshi Nakadai; Reo Maruyama
Source: check_circle
Crossref

Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma

The Journal of Pathology
2024-05-11 | Journal article
DOI: 10.1002/path.6278
Part of ISSN: 0022-3417
Part of ISSN: 1096-9896
Contributors: Osamu Gotoh; Yuko Sugiyama; Akiko Tonooka; Mayuko Kosugi; Sunao Kitaura; Ryu Minegishi; Masatoshi Sano; Sayuri Amino; Rie Furuya; Norio Tanaka et al.
Source: Self-asserted source
Kohei Kumegawa

Human Neuralized is a novel tumour suppressor targeting Wnt/β‐catenin signalling in colon cancer

EMBO reports
2023-08-03 | Journal article | Author
DOI: 10.15252/embr.202256335
Part of ISSN: 1469-221X
Part of ISSN: 1469-3178
Contributors: JOO MI; Tae-Hong Kang; Yu Kyeong Han; Ha Young Park; Ju Hwan Yang; Jin-Han Bae; Jung‐Soo Suh; Tae-Jin Kim; Joong‐Gook Kim; Yan‐Hong Cui et al.
Source: Self-asserted source
Kohei Kumegawa

TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells

Cell Death & Disease
2023-07-13 | Journal article | Author
DOI: 10.1038/s41419-023-05953-3
Part of ISSN: 2041-4889
Contributors: Hiroshi Kitajima; Reo Maruyama; Takeshi Niinuma; Eiichiro Yamamoto; Akira Takasawa; Kumi Takasawa; Kazuya Ishiguro; Akihiro Tsuyada; Ryo Suzuki; Gota Sudo et al.
Source: Self-asserted source
Kohei Kumegawa

HEY1-NCOA2 expression modulates chondrogenic differentiation and induces mesenchymal chondrosarcoma in mice

JCI Insight
2023-05-22 | Journal article
DOI: 10.1172/jci.insight.160279
Contributors: Miwa Tanaka; Mizuki Homme; Yasuyo Teramura; Kohei Kumegawa; Yukari Yamazaki; Kyoko Yamashita; Motomi Osato; Reo Maruyama; Takuro Nakamura
Source: check_circle
Crossref

FOXD1 is associated with poor outcome and maintains tumor-promoting enhancer–gene programs in basal-like breast cancer

Frontiers in Oncology
2023-05-10 | Journal article
DOI: 10.3389/fonc.2023.1156111
Part of ISSN: 2234-943X
Contributors: Kohei Kumegawa; Liying Yang; Kenichi Miyata; Reo Maruyama
Source: Self-asserted source
Kohei Kumegawa

ASPSCR1::TFE3 orchestrates the angiogenic program of alveolar soft part sarcoma

Nature Communications
2023-04-07 | Journal article
DOI: 10.1038/s41467-023-37049-z
Contributors: Miwa Tanaka; Surachada Chuaychob; Mizuki Homme; Yukari Yamazaki; Ruyin Lyu; Kyoko Yamashita; Keisuke Ae; Seiichi Matsumoto; Kohei Kumegawa; Reo Maruyama et al.
Source: check_circle
Crossref

Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility

British Journal of Cancer
2023-03-30 | Journal article
DOI: 10.1038/s41416-023-02178-1
Contributors: Kohei Kumegawa; Sumito Saeki; Yoko Takahashi; Liying Yang; Tomo Osako; Tomoyoshi Nakadai; Sayuri Amino; Tetsuyo Maeda; Chikako Takahata; Seiichi Mori et al.
Source: check_circle
Crossref

Correction: Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility

British Journal of Cancer
2023-03-30 | Journal article
DOI: 10.1038/s41416-023-02206-0
Contributors: Kohei Kumegawa; Sumito Saeki; Yoko Takahashi; Liying Yang; Tomo Osako; Tomoyoshi Nakadai; Sayuri Amino; Tetsuyo Maeda; Chikako Takahata; Seiichi Mori et al.
Source: check_circle
Crossref

Transcriptomic intratumor heterogeneity of breast cancer patient-derived organoids may reflect the unique biological features of the tumor of origin

Breast Cancer Research
2023-02-21 | Journal article
DOI: 10.1186/s13058-023-01617-4
Part of ISSN: 1465-542X
Contributors: Sumito Saeki; Kohei Kumegawa; Yoko Takahashi; Liying  Yang; Tomo Osako; Mahmut Yasen; Kazutaka Otsuji; Kenichi Miyata; Kaoru Yamakawa; Jun Suzuka et al.
Source: Self-asserted source
Kohei Kumegawa

Two target gene activation pathways for orphan ERR nuclear receptors

Cell Research
2023-01-16 | Journal article
DOI: 10.1038/s41422-022-00774-z
Part of ISSN: 1748-7838
Contributors: Tomoyoshi Nakadai; Miho Shimada; Keiichi Ito; Murat Alper Cevher; Chi-Shuen Chu; Kohei Kumegawa; Reo Maruyama; Sohail Malik; Robert G. Roeder
Source: Self-asserted source
Kohei Kumegawa

Estrogen receptor α K303R mutation reorganizes its binding to forkhead box protein A1 regions and induces chromatin opening

Molecular Biology Reports
2022-11-27 | Journal article
DOI: 10.1007/s11033-022-08089-3
Part of ISSN: 0301-4851
Part of ISSN: 1573-4978
Contributors: Tomoyoshi Nakadai; Liying Yang; Kohei Kumegawa; Reo Maruyama
Source: Self-asserted source
Kohei Kumegawa

GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer

npj Breast Cancer
2022-06-08 | Journal article
DOI: 10.1038/s41523-022-00438-6
Part of ISSN: 2374-4677
Contributors: Kohei Kumegawa; Yoko Takahashi; Sumito Saeki; Liying Yang; Tomoyoshi Nakadai; Tomo Osako; Seiichi Mori; Tetsuo Noda; Shinji Ohno; Takayuki Ueno et al.
Source: Self-asserted source
Kohei Kumegawa

A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer

Scientific Reports
2016-05-24 | Journal article
DOI: 10.1038/srep26699
Part of ISSN: 2045-2322
Contributors: Kohei Kumegawa; Reo Maruyama; Eiichiro Yamamoto; Masami Ashida; Hiroshi Kitajima; Akihiro Tsuyada; Takeshi Niinuma; Masahiro Kai; Hiro-o Yamano; Tamotsu Sugai et al.
Source: Self-asserted source
Kohei Kumegawa

Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer

Cancer Prevention Research
2014-10-01 | Journal article
DOI: 10.1158/1940-6207.capr-14-0162
Part of ISSN: 1940-6207
Part of ISSN: 1940-6215
Contributors: Taku Harada; Eiichiro Yamamoto; Hiro-o Yamano; Masanori Nojima; Reo Maruyama; Kohei Kumegawa; Masami Ashida; Kenjiro Yoshikawa; Tomoaki Kimura; Eiji Harada et al.
Source: Self-asserted source
Kohei Kumegawa

Peer review (1 review for 1 publication/grant)

Review activity for Breast cancer. (1)
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