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Scopus Author ID: 55936216900

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Employment (3)

University of Oxford: Oxford, Oxfordshire, GB

(Christ Church; Weatherall Institute of Molecular Medicine; Chinese Academy of Medical Sciences)
Employment
Source: check_circle
ORCID Integration at the University of Oxford

MRC Weatherall Institute of Molecular Medicine: Oxford, Oxfordshire, GB

2018-10-01 to 2023-03 | Postdoctoral Scientist (MRC Weatherall Institute of Molecular Medicine)
Employment
Source: Self-asserted source
Yi-Ling Chen

National Taiwan University: Taipei, TW

2011-08 to 2014-08 | Research Assistant (Graduate Institute of Immunology, College of Medicine)
Employment
Source: Self-asserted source
Yi-Ling Chen

Education and qualifications (3)

University of Oxford: Oxford, Oxfordshire, GB

2014-10-01 to 2018-09-30 | D.Phil (Radcliffe Department of Medicine)
Education
Source: Self-asserted source
Yi-Ling Chen

National Taiwan University: Taipei, TW

2009-09 to 2011-07 | Master of Science (Graduate Institute of Immunology)
Education
Source: Self-asserted source
Yi-Ling Chen

National Central University: Taoyuan, TW

2005-09 to 2009-07 | Bachelor of Science (Life Sciences) (Department of Life Sciences)
Education
Source: Self-asserted source
Yi-Ling Chen

Works (25)

CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms

Cell
2023-10 | Journal article
DOI: 10.1016/j.cell.2023.08.022
Part of ISSN: 0092-8674
Contributors: Shouxiong Huang; Adam Shahine; Tan-Yun Cheng; Yi-Ling Chen; Soo Weei Ng; Gautham R. Balaji; 0000-0002-5116-2814; Stephanie Gras; Clare S. Hardman; John D. Altman et al.
Source: Self-asserted source
Yi-Ling Chen

Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation

Science Immunology
2023-06-30 | Journal article | Author
DOI: 10.1126/sciimmunol.add9232
Part of ISSN: 2470-9468
Contributors: Yi-Ling Chen; Jessica Soo Weei Ng; Rosana Ottakandathil Babu; Jeongmin Woo; Janina Nahler; Clare Hardman; Kurupati Prathiba; Lea Nussbaum; Fei; Tao Dong et al.
Source: Self-asserted source
Yi-Ling Chen

Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a

Nature Immunology
2023-01 | Journal article | Author
DOI: 10.1038/s41590-022-01375-z
Part of ISSN: 1529-2908
Part of ISSN: 1529-2916
Contributors: Gwennaelle C Monnot; Marcin Wegrecki; Tan-Yun Cheng; Yi-Ling Chen; Brigitte N. Sallee; Reka Chakravarthy; Ioanna Maria Karantza; Shin Yi Tin; Alexandra E. Khaleel; isha monga et al.
Source: Self-asserted source
Yi-Ling Chen

CD1a promotes systemic manifestations of skin inflammation

Nature Communications
2022-12-07 | Journal article | Author
DOI: 10.1038/s41467-022-35071-1
Part of ISSN: 2041-1723
Contributors: Clare Hardman; Yi-Ling Chen; Marcin Wegrecki; Jessica Soo Weei Ng; Robert Murren; Davinderpreet Mangat; John-Paul Silva; Rebecca Munro; Win-Yan Chan; Victoria O’Dowd et al.
Source: Self-asserted source
Yi-Ling Chen

Dengue virus co-opts innate type 2 pathways to escape early control of viral replication

Communications Biology
2022-07-22 | Journal article | Author
DOI: 10.1038/s42003-022-03682-5
Part of ISSN: 2399-3642
Contributors: Chathuranga L. Fonseka; Clare Hardman; Jeongmin. Woo; Randeep Singh; Janina Nahler; Jiahe Yang; Yi-Ling Chen; Achala Kamaladasa; Tehani Silva; Maryam Salimi et al.
Source: Self-asserted source
Yi-Ling Chen

Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19

Wellcome Open Research
2022-06-21 | Journal article
DOI: 10.12688/wellcomeopenres.17904.1
Part of ISSN: 2398-502X
Source: Self-asserted source
Yi-Ling Chen

Phospholipase activity of acyloxyacyl hydrolase induces IL‐22‐producing CD1a‐autoreactive T cells in individuals with psoriasis

European Journal of Immunology
2022-03 | Journal article
DOI: 10.1002/eji.202149485
Part of ISSN: 0014-2980
Part of ISSN: 1521-4141
Source: Self-asserted source
Yi-Ling Chen

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Cell
2022-01 | Journal article
DOI: 10.1016/j.cell.2022.01.012
Part of ISSN: 0092-8674
Source: Self-asserted source
Yi-Ling Chen

Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19

Allergy, Asthma & Clinical Immunology
2021-12 | Journal article
DOI: 10.1186/s13223-021-00569-8
Part of ISSN: 1710-1492
Source: Self-asserted source
Yi-Ling Chen

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

PLOS Pathogens
2021-09-16 | Journal article
DOI: 10.1371/journal.ppat.1009804
Part of ISSN: 1553-7374
Source: Self-asserted source
Yi-Ling Chen

CD1a selectively captures endogenous cellular lipids that broadly block T cell response

Journal of Experimental Medicine
2021-07-05 | Journal article
DOI: 10.1084/jem.20202699
Part of ISSN: 0022-1007
Part of ISSN: 1540-9538
Source: Self-asserted source
Yi-Ling Chen

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent

Science Immunology
2021-05-28 | Journal article
DOI: 10.1126/sciimmunol.abe5084
Part of ISSN: 2470-9468
Source: Self-asserted source
Yi-Ling Chen

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Nature Immunology
2020-11 | Journal article
DOI: 10.1038/s41590-020-0782-6
Part of ISSN: 1529-2908
Part of ISSN: 1529-2916
Source: Self-asserted source
Yi-Ling Chen

Innate Lymphocyte Mechanisms in Skin Diseases

Annual Review of Immunology
2020-04-26 | Journal article
DOI: 10.1146/annurev-immunol-082919-093554
Part of ISSN: 0732-0582
Part of ISSN: 1545-3278
Source: Self-asserted source
Yi-Ling Chen

Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation

The Journal of Experimental Medicine
2020-03-02 | Journal article
DOI: 10.1084/jem.20190811
Part of ISSN: 0022-1007
Part of ISSN: 1540-9538
Source: Self-asserted source
Yi-Ling Chen

Fevipiprant, a selective prostaglandin D<inf>2</inf> receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function

Journal of Allergy and Clinical Immunology
2019 | Journal article
DOI: 10.1016/j.jaci.2019.02.015
EID:

2-s2.0-85063320035
Contributors: Hardman, C.; Chen, W.; Luo, J.; Batty, P.; Chen, Y.-L.; Nahler, J.; Wu, Y.; Pavord, I.D.; Erpenbeck, V.J.; Sandham, D.A. et al.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis

Science translational medicine
2019 | Journal article
DOI: 10.1126/scitranslmed.aax2945
EID:

2-s2.0-85074088592
Contributors: Chen, Y.-L.; Gutowska-Owsiak, D.; Hardman, C.S.; Westmoreland, M.; MacKenzie, T.; Cifuentes, L.; Waithe, D.; Lloyd-Lavery, A.; Marquette, A.; Londei, M. et al.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells

Journal of Allergy and Clinical Immunology
2019 | Journal article
DOI: 10.1016/j.jaci.2019.08.008
EID:

2-s2.0-85072565406
Contributors: Luo, J.; Wu, Y.; Shrimanker, R.; Go, S.; Ye, Y.; Hardman, C.; Nahler, J.; Chen, Y.-L.; Stöger, L.; Zeng, N. et al.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells

Science immunology
2017 | Journal article
DOI: 10.1126/sciimmunol.aan5918
EID:

2-s2.0-85041363735
Contributors: Hardman, C.S.; Chen, Y.-L.; Salimi, M.; Jarrett, R.; Johnson, D.; Järvinen, V.J.; Owens, R.J.; Repapi, E.; Cousins, D.J.; Barlow, J.L. et al.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages

Scientific Reports
2017 | Journal article
DOI: 10.1038/srep46165
EID:

2-s2.0-85017111069
Contributors: Yang, J.-X.; Hsieh, K.-C.; Chen, Y.-L.; Lee, C.-K.; Conti, M.; Chuang, T.-H.; Wu, C.-P.; Catherine Jin, S.-L.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a

Journal of Experimental Medicine
2016 | Journal article
DOI: 10.1084/JEM.20160258
EID:

2-s2.0-85017204228
Contributors: Cheung, K.L.; Jarrett, R.; Subramaniam, S.; Salimi, M.; Gutowska-Owsiak, D.; Chen, Y.-L.; Hardman, C.; Xue, L.; Cerundolo, V.; Ogg, G.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Efficient generation of plasmacytoid dendritic cell from common lymphoid progenitors by Flt3 ligand

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0135217
EID:

2-s2.0-84943171149
Contributors: Chen, Y.-L.; Chang, S.; Chen, T.-T.; Lee, C.-K.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Phosphodiesterase 4B is essential for lipopolysaccharide-induced CC chemokine ligand 3 production in mouse macrophages

Journal of Medical Sciences (Taiwan)
2015 | Journal article
DOI: 10.4103/1011-4564.158674
EID:

2-s2.0-84931333776
Contributors: Lai, C.-R.; Lo, H.-C.; Chen, Y.-L.; Yang, J.-X.; Ding, S.-L.; Hsu, H.-H.; Conti, M.; Wu, C.-P.; Catherine Jin, S.-L.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1

Biochemical Journal
2015 | Journal article
DOI: 10.1042/BJ20140644
EID:

2-s2.0-84934976197
Contributors: Blaszczyk, K.; Olejnik, A.; Nowicka, H.; Ozgyin, L.; Chen, Y.-L.; Chmielewski, S.; Kostyrko, K.; Wesoly, J.; Balint, B.L.; Lee, C.-K. et al.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors

Journal of Experimental Medicine
2013 | Journal article
DOI: 10.1084/jem.20130536
EID:

2-s2.0-84888100092
Contributors: Chen, Y.-L.; Chen, T.-T.; Pai, L.-M.; Wesoly, J.; Bluyssen, H.A.R.; Lee, C.-K.
Source: Self-asserted source
Yi-Ling Chen via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Journal of allergy and clinical Immunology. (1)
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