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Scopus Author ID: 16319700500

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Employment (2)

University of California Irvine: Irvine, CA, US

2018-07-01 to present | Assistant Professor (Neurobiology and Behavior)
Employment
Source: Self-asserted source
Vivek Swarup

UCLA Life Sciences: Los Angeles, CA, US

2012-07-01 to present | Postdoctoral Scholar (Neurology)
Employment
Source: Self-asserted source
Vivek Swarup

Education and qualifications (3)

University Laval: Quebec, QC, CA

2007-09-04 to 2012-04-04 | PhD (Center of Research of CHUQ)
Education
Source: Self-asserted source
Vivek Swarup

National Brain Research Centre: Manesar, Haryana, IN

2007-06-01 to 2009-07-01 | Masters of Science in Neuroscience
Education
Source: Self-asserted source
Vivek Swarup

Banaras Hindu University: Varanasi, Uttar Pradesh, IN

2002-07-01 to 2005-06-01 | Bachelor of Science Zoology Hons (Zoology)
Education
Source: Self-asserted source
Vivek Swarup

Professional activities (1)

Society for Neuroscience: Washington, DC, US

Membership
Source: Self-asserted source
Vivek Swarup

Funding (2)

Dynamic epigenomic landscape of opioid abuse following early-life adversity

2022-07-01 to 2027-04-30 | Grant
National Institute on Drug Abuse (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12917614
GRANT_NUMBER: U01DA053826
Source: Self-asserted source
Vivek Swarup via DimensionsWizard

Oligodendrocyte heterogeneity in Alzheimer' s disease

2021-04-01 to 2024-03-31 | Grant
National Institute on Aging (Baltimore, US)
URL: https://app.dimensions.ai/details/grant/grant.9644957
GRANT_NUMBER: RF1AG071683
Source: Self-asserted source
Vivek Swarup via DimensionsWizard

Works (50 of 51)

Items per page:
Page 1 of 2

Dynamic Transcriptomic Remodeling in Human Neural Progenitor Cells Reveals Mechanisms for Vision Preservation in Retinitis Pigmentosa Model

2025-01-07 | Preprint
DOI: 10.1101/2025.01.06.631620
Contributors: Saba Shahin; Shaughn Bell; Bin Lu; Somanshu Banerjee; Vivek Swarup; Hui Xu; Jason Chetsawang; Stephany Ramirez; Jorge S Alfaro; Alexander Laperle et al.
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Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease

2024-10-22 | Preprint
DOI: 10.1101/2024.10.21.619538
Contributors: Kate I. Tsourmas; Claire A. Butler; Nellie E. Kwang; Zachary R. Sloane; Koby J. G. Dykman; Ghassan O. Maloof; Christiana A. Prekopa; Robert P. Krattli; Sanad M. El-Khatib; Vivek Swarup et al.
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Crossref

Generation of an inducible destabilized-domain Cre mouse line to target disease associated microglia

2024-09-19 | Preprint
DOI: 10.1101/2024.09.18.613773
Contributors: Caden M. Henningfield; Nellie Kwang; Kate Inman Tsourmas; Jonathan Neumann; Shimako Kawauchi; Vivek Swarup; Grant R. MacGregor; Kim N. Green
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Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice

Nature Neuroscience
2024-08 | Journal article
DOI: 10.1038/s41593-024-01684-6
Contributors: Timothy M. O’Shea; Yan Ao; Shinong Wang; Yilong Ren; Amy L. Cheng; Riki Kawaguchi; Zechuan Shi; Vivek Swarup; Michael V. Sofroniew
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Crossref

Short-chain fatty acids abrogate Japanese encephalitis virus-induced inflammation in microglial cells via miR-200a-3p/ZBTB20/IKβα axis

mBio
2024-07-17 | Journal article
DOI: 10.1128/mbio.01321-24
Contributors: Atreye Majumdar; Indira Priya Siva Venkatesh; Vivek Swarup; Anirban Basu; Nisha K. Duggal
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Crossref

Gene networks and systems biology in Alzheimer's disease: Insights from multi‐omics approaches

Alzheimer's & Dementia
2024-05 | Journal article
DOI: 10.1002/alz.13790
Contributors: Negin Rahimzadeh; Shushrruth Sai Srinivasan; Jing Zhang; Vivek Swarup
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Crossref

Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma

Neuro-Oncology Advances
2024-01-01 | Journal article
DOI: 10.1093/noajnl/vdae005
Contributors: Kunal S Patel; Kaleab K Tessema; Riki Kawaguchi; Lindsey Dudley; Alvaro G Alvarado; Sree Deepthi Muthukrishnan; Travis Perryman; Akifumi Hagiwara; Vivek Swarup; Linda M Liau et al.
Source: check_circle
Crossref

hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data

Cell Reports Methods
2023-06 | Journal article
DOI: 10.1016/j.crmeth.2023.100498
Contributors: Samuel Morabito; Fairlie Reese; Negin Rahimzadeh; Emily Miyoshi; Vivek Swarup
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Crossref

Integrin-Driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

The Journal of Neuroscience
2023-06-28 | Journal article
DOI: 10.1523/JNEUROSCI.2076-22.2023
Contributors: Menghon Cheah; Yuyan Cheng; Veselina Petrova; Anda Cimpean; Pavla Jendelova; Vivek Swarup; Clifford J. Woolf; Daniel H. Geschwind; James W. Fawcett
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Crossref

Proteomic Data Advance Targeted Drug Development for Neurogenerative Diseases

Biological Psychiatry
2023-05 | Journal article
DOI: 10.1016/j.biopsych.2023.02.003
Contributors: Nora E. Emerson; Vivek Swarup
Source: check_circle
Crossref

Data from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.c.6551028.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Data from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.c.6551028
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Figure S1 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545789
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Figure S1 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545789.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
Source: check_circle
Crossref

Figure S2 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545786
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Figure S2 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545786.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
Source: check_circle
Crossref

Figure S3 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545783
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Figure S3 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545783.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Figure S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545780.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Figure S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545780
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Figure S5 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545777
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Figure S5 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545777.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Figure S6 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545774
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Figure S6 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545774.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Table S1 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545771.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Table S1 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545771
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Table S2 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545768.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Table S2 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545768
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Table S3 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545765
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Table S3 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545765.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Table S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545762.v1
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Table S4 from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

2023-04-04 | Preprint
DOI: 10.1158/2767-9764.22545762
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Crossref

Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma

2022-10-13 | Preprint
DOI: 10.1101/2022.10.10.511639
Contributors: Kunal S. Patel; Kaleab K. Tessema; Riki Kawaguchi; Alvaro G. Alvarado; Sree Deepthi Muthukrishnan; Akifumi Hagiwara; Vivek Swarup; Linda M. Liau; Anthony Wang; William Yong et al.
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Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue

STAR Protocols
2022-09 | Journal article
DOI: 10.1016/j.xpro.2022.101491
Contributors: Zechuan Shi; Sudeshna Das; Samuel Morabito; Emily Miyoshi; Vivek Swarup
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Crossref

High dimensional co-expression networks enable discovery of transcriptomic drivers in complex biological systems

2022-09-23 | Preprint
DOI: 10.1101/2022.09.22.509094
Contributors: Samuel Morabito; Fairlie Reese; Negin Rahimzadeh; Emily Miyoshi; Vivek Swarup
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Crossref

Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

Cancer Research Communications
2022-09-23 | Journal article
DOI: 10.1158/2767-9764.CRC-22-0003
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Dan R. Laks; Aparna Bhaduri; Vivek Swarup; David A. Nathanson; Daniel H. Geschwind et al.
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Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

2021-12-07 | Preprint
DOI: 10.1101/2021.12.07.471602
Contributors: Menghon Cheah; Yuyan Cheng; Veselina Petrova; Anda Cimpean; Pavla Jendelova; Vivek Swarup; Clifford J. Woolf; Daniel H. Geschwind; James W. Fawcett
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Crossref

Cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area

Neuropsychopharmacology
2021-09-21 | Journal article
DOI: 10.1038/s41386-021-01031-4
Contributors: Rianne R. Campbell; Siwei Chen; Joy H. Beardwood; Alberto J. López; Lilyana V. Pham; Ashley M. Keiser; Jessica E. Childs; Dina P. Matheos; Vivek Swarup; Pierre Baldi et al.
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Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R +/− mouse model of ALSP, which can be rescued via CSF1R inhibitors

Science Advances
2021-08-27 | Journal article
DOI: 10.1126/sciadv.abg1601
Contributors: Miguel A. Arreola; Neelakshi Soni; Joshua D. Crapser; Lindsay A. Hohsfield; Monica R. P. Elmore; Dina P. Matheos; Marcelo A. Wood; Vivek Swarup; Ali Mortazavi; Kim N. Green
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Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

Nature Genetics
2021-08-08 | Journal article
DOI: 10.1038/s41588-021-00894-z
Contributors: Samuel Morabito; Emily Miyoshi; Neethu Michael; Saba Shahin; Alessandra Cadete Martini; Elizabeth Head; Justine Silva; Kelsey Leavy; Mari Perez-Rosendahl; Vivek Swarup
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Pathway-based approach reveals differential sensitivity of glioblastoma to E2F1 inhibition

2021-06-19 | Other
DOI: 10.1101/2021.06.19.449118
Contributors: Alvaro G. Alvarado; Kaleab Tessema; Sree Deepthi Muthukrishnan; Mackenzie Sober; Riki Kawaguchi; Aparna Bhaduri; Vivek Swarup; David A Nathanson; Steven A. Goldman; Harley I. Kornblum
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Crossref

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

Nature Communications
2021-04-23 | Journal article
DOI: 10.1038/s41467-021-22624-z
Contributors: David Baglietto-Vargas; Stefania Forner; Lena Cai; Alessandra C. Martini; Laura Trujillo-Estrada; Vivek Swarup; Marie Minh Thu Nguyen; Kelly Do Huynh; Dominic I. Javonillo; Kristine Minh Tran et al.
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Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats

Neuropsychopharmacology
2021-04-14 | Journal article
DOI: 10.1038/s41386-020-00839-w
Contributors: Christina M. Ruiz; Alexa Torrens; Erik Castillo; Christina R. Perrone; Jenny Cevallos; Victoria C. Inshishian; Eden V. Harder; Drew N. Justeson; Marilyn A. Huestis; Vivek Swarup et al.
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Unexpected Role of Physiological Estrogen in Acute Stress-Induced Memory Deficits

The Journal of Neuroscience
2021-01-27 | Journal article
DOI: 10.1523/JNEUROSCI.2146-20.2020
Contributors: Rachael E. Hokenson; Annabel K. Short; Yuncai Chen; Aidan L. Pham; Emily T. Adams; Jessica L. Bolton; Vivek Swarup; Christine M. Gall; Tallie Z. Baram
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Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression

Cell Reports
2020-11 | Journal article
DOI: 10.1016/j.celrep.2020.108398
Contributors: Jessica E. Rexach; Damon Polioudakis; Anna Yin; Vivek Swarup; Timothy S. Chang; Tam Nguyen; Arjun Sarkar; Lawrence Chen; Jerry Huang; Li-Chun Lin et al.
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Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease

Human Molecular Genetics
2020-10-10 | Journal article
DOI: 10.1093/hmg/ddaa182
Contributors: Samuel Morabito; Emily Miyoshi; Neethu Michael; Vivek Swarup
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Crossref

Single-soma transcriptomics of tangle-bearing neurons in Alzheimer’s disease reveals the signatures of tau-associated synaptic dysfunction

2020-05-13 | Preprint
DOI: 10.1101/2020.05.11.088591
Contributors: Marcos Otero-Garcia; Yue-Qiang Xue; Tamara Shakouri; Yongning Deng; Samuel Morabito; Thomas Allison; William E. Lowry; Riki Kawaguchi; Vivek Swarup; Inma Cobos
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Identification of conserved proteomic networks in neurodegenerative dementia

2019-10-31 | Other
DOI: 10.1101/825802
Contributors: Vivek Swarup; Timothy S. Chang; Duc M. Duong; Eric B. Dammer; James J. Lah; Erik E.C.B. Johnson; Nicholas T. Seyfried; Allan I. Levey; Daniel H. Geschwind
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Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease

2019-07-07 | Other
DOI: 10.1101/695221
Contributors: Samuel Morabito; Emily Miyoshi; Neethu Michael; Vivek Swarup
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Dementia risk genes engage gene networks poised to tune the immune response towards chronic inflammatory states

2019-04-04 | Other
DOI: 10.1101/597542
Contributors: Jessica Rexach; Vivek Swarup; Timothy Chang; Daniel Geschwind
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Peer review (41 reviews for 15 publications/grants)

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