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Education and qualifications (3)

University of Oxford University College Oxford: Oxford, Oxfordshire, GB

2016 to 2021 | DPhil in Medical Sciences
Education
Source: Self-asserted source
Edward Jenkins

University of Cambridge: Cambridge, Cambridgeshire, GB

2015-10 to 2016-10 | MPhil in Medical Sciences (Medicine)
Education
Source: Self-asserted source
Edward Jenkins

Imperial College London: London, London, GB

2011-10 to 2015-10 | BSc Biological Sciences with Management (4 years)
Education
Source: Self-asserted source
Edward Jenkins

Funding (1)

Spatiotemporal control of cytoskeletal remodeling in lymphocytes

2022-01-03 to 2026-01-02 | Grant
Wellcome Trust (London, UK, GB)
GRANT_NUMBER:

224040/Z/21/Z

Part of GRANT_NUMBER:

PLM23095
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WT Grant Tracker

Works (13)

Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes

2025-01-06 | Preprint
DOI: 10.1101/2025.01.06.631424
Contributors: Jake Burton; Jesús A. Siller-Farfán; Violaine Andre; Edward Jenkins; Michael I. Barton; Sofia Bustamante Eguiguren; Jose Cabezas Caballero; Simon J. Davis; Thomas R Weikl; P. Anton van der Merwe et al.
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Crossref

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

Cell Reports
2024-05 | Journal article
DOI: 10.1016/j.celrep.2024.114152
Part of ISSN: 2211-1247
Contributors: Zhu Liang; Andreas Damianou; Iolanda Vendrell; Edward Jenkins; Frederik H. Lassen; Sam J. Washer; Athina Grigoriou; Guihai Liu; Gangshun Yi; Hantao Lou et al.
Source: Self-asserted source
Edward Jenkins

A general algorithm for consensus 3D cell segmentation from 2D segmented stacks

2024-05-06 | Preprint
DOI: 10.1101/2024.05.03.592249
Contributors: Felix Yuran Zhou; Clarence Yapp; Zhiguo Shang; Stephan Daetwyler; Zach Marin; Md Torikul Islam; Benjamin A Nanes; Edward Jenkins; Gabriel M Gihana; Bo-Jui Chang et al.
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Crossref

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases

Immunity
2024-02 | Journal article
DOI: 10.1016/j.immuni.2024.01.007
Part of ISSN: 1074-7613
Contributors: Anna H. Lippert; Christopher Paluch; Meike Gaglioni; Mai T. Vuong; James McColl; Edward Jenkins; Martin Fellermeyer; Joseph Clarke; Sumana Sharma; Sara Moreira da Silva et al.
Source: Self-asserted source
Edward Jenkins

Antigen discrimination by T cells relies on size-constrained microvillar contact

Nature Communications
2023-03-23 | Journal article
DOI: 10.1038/s41467-023-36855-9
Contributors: Edward Jenkins; Markus Körbel; Caitlin O’Brien-Ball; James McColl; Kevin Y. Chen; Mateusz Kotowski; Jane Humphrey; Anna H. Lippert; Heather Brouwer; Ana Mafalda Santos et al.
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Crossref

The current state and future of T-cell exhaustion research

Oxford Open Immunology
2023-01-12 | Journal article
DOI: 10.1093/oxfimm/iqad006
Contributors: Edward Jenkins; Toby Whitehead; Martin Fellermeyer; Simon J Davis; Sumana Sharma
Source: check_circle
Crossref

The kinase occupancy of T cell coreceptors reconsidered.

Proceedings of the National Academy of Sciences of the United States of America
2022-12 | Journal article
DOI: 10.1073/pnas.2213538119
PMID: 36454761
PMC: PMC9894195
Contributors: Mørch AM; Schneider F; Jenkins E; Santos AM; Fraser SE; Davis SJ; Dustin ML
Source: Self-asserted source
Edward Jenkins via Europe PubMed Central

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling

Proceedings of the National Academy of Sciences
2021-09-28 | Journal article
DOI: 10.1073/pnas.2024250118
Contributors: Kevin Y. Chen; Edward Jenkins; Markus Körbel; Aleks Ponjavic; Anna H. Lippert; Ana Mafalda Santos; Nicole Ashman; Caitlin O'Brien-Ball; Jemma McBride; David Klenerman et al.
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Crossref

Aggregation and partial immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells

FEBS Letters
2021-06-23 | Journal article
DOI: 10.1002/1873-3468.14153
Source: Self-asserted source
Edward Jenkins

HLA-E–restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities

Science Immunology
2021-03-25 | Journal article
DOI: 10.1126/sciimmunol.abg1703
Source: Self-asserted source
Edward Jenkins

Soft Polydimethylsiloxane-Supported Lipid Bilayers for Studying T Cell Interactions

2020-11-25 | Journal article
DOI: 10.1016/j.bpj.2020.11.021
Source: Self-asserted source
Edward Jenkins

The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.

Biophysical journal
2020-01-28 | Journal article
DOI: 10.1016/j.bpj.2020.01.019
PMID: 32075748
Source: Self-asserted source
Edward Jenkins

Reconstitution of immune cell interactions in free-standing membranes.

Journal of cell science
2018-10-02 | Journal article
DOI: 10.1242/jcs.219709
PMID: 30209137
PMC: PMC6398472
Source: Self-asserted source
Edward Jenkins
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