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Employment (1)

Universitair Medisch Centrum Utrecht: Utrecht, Utrecht, NL

2018-06 to present | PhD student (CDL)
Employment
Source: Self-asserted source
Lotte Slenders

Education and qualifications (1)

Universiteit Utrecht: Utrecht, Utrecht, NL

Master of Science
Education
Source: Self-asserted source
Lotte Slenders

Works (16)

CD163+ Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma

Circulation Research
2024-07-05 | Journal article
DOI: 10.1161/CIRCRESAHA.123.324082
Contributors: Masayuki Mori; Atsushi Sakamoto; Rika Kawakami; Liang Guo; Lotte Slenders; Jose Verdezoto Mosquera; Saikat Kumar B. Ghosh; Marian Wesseling; Tatsuya Shiraki; Arielle Bellissard et al.
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Crossref

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans

Arteriosclerosis, Thrombosis, and Vascular Biology
2024-06 | Journal article
DOI: 10.1161/ATVBAHA.123.320692
Contributors: Ernest Diez Benavente; Robin J.G. Hartman; Tim R. Sakkers; Marian Wesseling; Yannicke Sloots; Lotte Slenders; Arjan Boltjes; Barend M. Mol; Gert J. de Borst; Dominique P.V. de Kleijn et al.
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Crossref

Human Plaque Myofibroblasts to Study Mechanisms of Atherosclerosis

Journal of the American Heart Association
2023-11-07 | Journal article
DOI: 10.1161/JAHA.123.030243
Contributors: Michele F. Buono; Ernest Diez Benavente; Lotte Slenders; Daisey Methorst; Daniëlle Tessels; Eloi Mili; Roxy Finger; Daniek Kapteijn; Mark Daniels; Noortje A. M. van den Dungen et al.
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Crossref

Female Gene Networks Are Expressed in Myofibroblast-Like Smooth Muscle Cells in Vulnerable Atherosclerotic Plaques

Arteriosclerosis, Thrombosis, and Vascular Biology
2023-10 | Journal article
DOI: 10.1161/ATVBAHA.123.319325
Contributors: Ernest Diez Benavente; Santosh Karnewar; Michele Buono; Eloi Mili; Robin J.G. Hartman; Daniek Kapteijn; Lotte Slenders; Mark Daniels; Redouane Aherrahrou; Tobias Reinberger et al.
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Crossref

Atherosclerotic plaque epigenetic age acceleration is characterized by mesenchymal reprogramming and poor prognosis

2023-02-18 | Preprint
DOI: 10.1101/2023.02.16.23286067
Contributors: Robin J. G. Hartman; Ernest Diez Benavente; Lotte Slenders; Arjan Boltjes; Barend M. Mol; Gert J. de Borst; Dominique P. V. de Kleijn; Koen H. M. Prange; Menno P. J. de Winther; Johan Kuiper et al.
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Crossref

Human primary plaque cell cultures to study mechanisms of atherosclerosis

2023-02-13 | Preprint
DOI: 10.1101/2023.02.09.527800
Contributors: Michele F. Buono; Ernest Diez Benavente; Lotte Slenders; Daisey Methorst; Daniёlle Tessels; Eloi Mili; Roxy Finger; Daniek Kapteijn; Mark Daniels; Noortje A. M. van den Dungen et al.
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Crossref

Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques

2023-02-11 | Preprint
DOI: 10.1101/2023.02.08.527690
Contributors: Ernest Diez Benavente; Santosh Karnewar; Michele Buono; Eloi Mili; Robin J. G. Hartman; Daniek Kapteijn; Lotte Slenders; Mark Daniels; Redouane Aherrahrou; Tobias Reinberger et al.
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Crossref

Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation

Nature Cardiovascular Research
2022-12-12 | Journal article
DOI: 10.1038/s44161-022-00171-0
Contributors: Michal Mokry; Arjan Boltjes; Lotte Slenders; Gemma Bel-Bordes; Kai Cui; Eli Brouwer; Joost M. Mekke; Marie A. C. Depuydt; Nathalie Timmerman; Farahnaz Waissi et al.
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Crossref

Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis

European Heart Journal Open
2022-01-11 | Journal article
DOI: 10.1093/ehjopen/oeab043
Contributors: Lotte Slenders; Lennart P L Landsmeer; Kai Cui; Marie A C Depuydt; Maarten Verwer; Joost Mekke; Nathalie Timmerman; Noortje A M van den Dungen; Johan Kuiper; Menno P J de Winther et al.
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Crossref

Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis

2021-11-24 | Other
DOI: 10.1101/2021.11.23.21266487
Contributors: Lotte Slenders; Lennart P. L. Landsmeer; Kai Cui; Marie A.C. Depuydt; Maarten Verwer; Joost Mekke; Nathalie Timmerman; Noortje A.M. van den Dungen; Johan Kuiper; Menno P.J. Winther et al.
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Crossref

The changing landscape of the vulnerable plaque: a call for fine-tuning of preclinical models

Vascular Pharmacology
2021-10 | Journal article
DOI: 10.1016/j.vph.2021.106924
Part of ISSN: 1537-1891
Source: Self-asserted source
Lotte Slenders

Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching

Circulation
2021-02-16 | Journal article
DOI: 10.1161/CIRCULATIONAHA.120.051231
Contributors: Robin J.G. Hartman; Katie Owsiany; Lijiang Ma; Simon Koplev; Ke Hao; Lotte Slenders; Mete Civelek; Michal Mokry; Jason C. Kovacic; Gerard Pasterkamp et al.
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Crossref

Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women

2021-01-29 | Preprint
Part of DOI: 10.1101/2021.01.28.428414
Source: Self-asserted source
Lotte Slenders

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Circulation Research
2020-11-06 | Journal article
DOI: 10.1161/circresaha.120.316770
Part of ISSN: 0009-7330
Part of ISSN: 1524-4571
Source: Self-asserted source
Lotte Slenders
grade
Preferred source (of 2)‎

TRIM46 Organizes Microtubule Fasciculation in the Axon Initial Segment

The Journal of Neuroscience
2019-06-19 | Journal article
DOI: 10.1523/jneurosci.3105-18.2019
Part of ISSN: 1529-2401
Source: Self-asserted source
Lotte Slenders

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

Neuron
2015-12 | Journal article
Part of ISSN: 0896-6273
Source: Self-asserted source
Lotte Slenders
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