Personal information

Extracellular matrix in stem cell maintenance and differentiation, Generation and analysis of mouse models with skeletal abnormal abnormalities or intervertebral disc degeneration, Molecular mechanisms for skeletal patterning: Joint formation and digit patterning, Role of cellular stress signals in the pathogenesis of osteochondrodysplasias
Hong Kong SAR China

Biography

Graduated from the University of Melbourne, with a Bachelor of Science (degree with honours), Master of Science and PhD, Prof. Chan continued research at his alma mater on heritable skeletal disorders with a focus on extracellular matrix proteins. He joined the University of Hong Kong in 1998, maintaining his research in skeletal biology using mouse as a model to address disease mechanisms in vivo, as well as human genetic studies to define genetic risk factors for common degenerative skeletal conditions such as intervertebral disc degeneration. His research contributed to the molecular understanding of many forms of the human osteochondrodysplasias. In recognition, he was presented with “The Premier’s Award for Health & Medical Research in Victoria, Australia; and more recently, he received the Croucher Senior Fellowship from the Croucher Foundation as recognition of his contribution to skeletal research in Hong Kong.

Activities

Peer review (22 reviews for 9 publications/grants)

Review activity for Bone Research. (1)
Review activity for Cell and tissue research. (2)
Review activity for iScience. (6)
Review activity for Matrix biology. (1)
Review activity for Nature communications (3)
Review activity for npj regenerative medicine. (2)
Review activity for Osteoarthritis and cartilage (4)
Review activity for PLOS genetics. (1)
Review activity for Stem cell research & therapy. (2)