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Employment (7)

Japan Synchrotoron Radiation Research Institute: Sayo, Hyogo, JP

2022-04-01 to present
Employment
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JASRI

Yale School of Medicine: New Haven, CT, US

2014-09-01 to 2024-03-31 | Visiting Scientist (Cellular and Molecular Physiology)
Employment
Source: Self-asserted source
Hideki Shigematsu

RIKEN SPring-8 Center: 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, JP

2018-02-01 to 2022-03-31 | Research Scientist (Research Infrastructure Group)
Employment
Source: Self-asserted source
Hideki Shigematsu

Yokohama City University Graduate School of Medical Life Science: Yokohma, JP

2016-04-01 to 2018-03-31 | Visiting Assocciate Professor
Employment
Source: Self-asserted source
Hideki Shigematsu

Rigaku Kenkyujo Seimei Kino Kagaku Kenkyu Center: Yokohama, JP

2014-09-01 to 2018-01-31 | Senior Scientist
Employment
Source: Self-asserted source
Hideki Shigematsu

Yale University School of Medicine: New Haven, CT, US

2010-01-01 to 2014-08-31 | Associate Research Scientist and Manger of cryoEM in EM Core (Cellular and Molecular Physiology)
Employment
Source: Self-asserted source
Hideki Shigematsu

Okazaki Institute for Integrative Bioscience : Okazaki, JP

2005-01-01 to 2009-12-31
Employment
Source: Self-asserted source
Hideki Shigematsu

Education and qualifications (1)

Tokyo Institute of Technology Graduate School of Bioscience and Biotechnlogy: Tokyo, JP

1994-04-01 to 1999-09-30 | Ph. D. (Biotechnology)
Education
Source: Self-asserted source
Hideki Shigematsu

Works (50 of 53)

Items per page:
Page 1 of 2

Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1

Nature Chemical Biology
2024-05 | Journal article
Contributors: Mayuki Tanaka; Takeshi Yokoyama; Hironori Saito; Madoka Nishimoto; Kengo Tsuda; Naoyuki Sotta; Hideki Shigematsu; Mikako Shirouzu; Shintaro Iwasaki; Takuhiro Ito et al.
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Crossref

Monomer-dimer structural comparison in quinol-dependent nitric oxide reductase reveals a functional basis for superior enzymatic activity in the dimer

2024-05-17 | Preprint
Contributors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha
Source: check_circle
Crossref

Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein

Journal of Virology
2024-04-16 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: HANAKO ISHIMARU; Mitsuhiro Nishimura; Hideki Shigematsu; Maria Istiqomah Marini; Natsumi Hasegawa; Rei Takamiya; Sachiyo Iwata; Yasuko Mori
Source: Self-asserted source
Hideki Shigematsu

Structural insights into thermophilic chaperonin complexes

Structure
2024-03 | Journal article
Part of ISSN: 0969-2126
Contributors: Zengwei Liao; Chai C. Gopalasingam; Masafumi Kameya; Christoph Gerle; Hideki Shigematsu; Masaharu Ishii; Takatoshi Arakawa; Shinya Fushinobu
Source: Self-asserted source
Hideki Shigematsu

Deep learning driven de novo drug design based on gastric proton pump structures

Communications Biology
2023-09-19 | Journal article
Contributors: Kazuhiro Abe; Mami Ozako; Miki Inukai; Yoe Matsuyuki; Shinnosuke Kitayama; Chisato Kanai; Chiaki Nagai; Chai C. Gopalasingam; Christoph Gerle; Hideki Shigematsu et al.
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Crossref

Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants

Journal of Virology
2023-06-29 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Hanako Ishimaru; Mitsuhiro Nishimura; Lidya Handayani Tjan; Silvia Sutandhio; Maria Istiqomah Marini; Gema Barlian Effendi; Hideki Shigematsu; Koji Kato; Natsumi Hasegawa; Kaito Aoki et al.
Source: Self-asserted source
Hideki Shigematsu

TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction

Nature Communications
2023-01-11 | Journal article
Contributors: Kentaro Sakaniwa; Akiko Fujimura; Takuma Shibata; Hideki Shigematsu; Toru Ekimoto; Masaki Yamamoto; Mitsunori Ikeguchi; Kensuke Miyake; Umeharu Ohto; Toshiyuki Shimizu
Source: check_circle
Crossref

Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases

Nature Communications
2022-12-08 | Journal article
Contributors: Yuya Nishida; Sachiko Yanagisawa; Rikuri Morita; Hideki Shigematsu; Kyoko Shinzawa-Itoh; Hitomi Yuki; Satoshi Ogasawara; Ken Shimuta; Takashi Iwamoto; Chisa Nakabayashi et al.
Source: check_circle
Crossref

Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside

Science Advances
2022-09-09 | Journal article
Contributors: Hiroshi Inaba; Yurina Sueki; Muneyoshi Ichikawa; Arif Md. Rashedul Kabir; Takashi Iwasaki; Hideki Shigematsu; Akira Kakugo; Kazuki Sada; Tomoya Tsukazaki; Kazunori Matsuura
Source: check_circle
Crossref

Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 –tubulin complex

eLife
2022-09-06 | Journal article
Contributors: Shinya Taguchi; Juri Nakano; Tsuyoshi Imasaki; Tomoki Kita; Yumiko Saijo-Hamano; Naoki Sakai; Hideki Shigematsu; Hiromichi Okuma; Takahiro Shimizu; Eriko Nitta et al.
Source: check_circle
Crossref

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation

eLife
2022-06-28 | Journal article
Contributors: Tsuyoshi Imasaki; Satoshi Kikkawa; Shinsuke Niwa; Yumiko Saijo-Hamano; Hideki Shigematsu; Kazuhiro Aoyama; Kaoru Mitsuoka; Takahiro Shimizu; Mari Aoki; Ayako Sakamoto et al.
Source: check_circle
Crossref

Structural model of microtubule dynamics inhibition by Kinesin-4 from the crystal structure of KLP-12 –tubulin complex

2022-02-15 | Preprint
Contributors: Shinya Taguchi; Juri Nakano; Tsuyoshi Imasaki; Tomoki Kita; Yumiko Saijo-Hamano; Naoki Sakai; Hideki Shigematsu; Hiromichi Okuma; Takahiro Shimizu; Eriko Nitta et al.
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Crossref
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Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside

2022-01-28 | Preprint
Contributors: Hiroshi Inaba; Yurina Sueki; Muneyoshi Ichikawa; Arif Md. Rashedul Kabir; Takashi Iwasaki; Hideki Shigematsu; Akira Kakugo; Kazuki Sada; Kazunori Matsuura
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Crossref
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Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein

Structure
2021 | Journal article
EID:

2-s2.0-85097875286

Part of ISSN: 18784186 09692126
Contributors: Nojima, S.; Fujita, Y.; Kimura, K.T.; Nomura, N.; Suno, R.; Morimoto, K.; Yamamoto, M.; Noda, T.; Iwata, S.; Shigematsu, H. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation

Journal of Cell Biology
2021 | Journal article
EID:

2-s2.0-85101321075

Part of ISSN: 15408140 00219525
Contributors: Ayukawa, R.; Iwata, S.; Imai, H.; Kamimura, S.; Hayashi, M.; Ngo, K.X.; Minoura, I.; Uchimura, S.; Makino, T.; Shirouzu, M. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Improving particle quality in cryo-EM analysis using a PEGylation method.

Structure (London, England : 1993)
2021-05-27 | Journal article
Source: Self-asserted source
Hideki Shigematsu
grade
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CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre

2021-03-01 | Preprint
Contributors: Tsuyoshi Imasaki; Satoshi Kikkawa; Shinsuke Niwa; Yumiko Saijo-Hamano; Hideki Shigematsu; Kazuhiro Aoyama; Kaoru Mitsuoka; Mari Aoki; Ayako Sakamoto; Yuri Tomabechi et al.
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Crossref
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Cryo-EM structures of Toll-like receptors in complex with UNC93B1

Nature Structural & Molecular Biology
2021-02-11 | Journal article
Contributors: Hanako Ishida; Jinta Asami; Zhikuan Zhang; Tomohiro Nishizawa; Hideki Shigematsu; Umeharu Ohto; Toshiyuki Shimizu
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Crossref
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Electron cryo-microscopy for elucidating the dynamic nature of live-protein complexes

Biochimica et Biophysica Acta - General Subjects
2020 | Journal article
EID:

2-s2.0-85073560042

Part of ISSN: 18728006 03044165
Contributors: Shigematsu, H.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

GTP-dependent formation of straight oligomers leads to nucleation of microtubules

bioRxiv
2020 | Other
EID:

2-s2.0-85102721950

Part of ISSN: 26928205
Contributors: Ayukawa, R.; Iwata, S.; Imai, H.; Kamimura, S.; Hayashi, M.; Ngo, K.X.; Minoura, I.; Uchimura, S.; Makino, T.; Shirouzu, M. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structural analysis reveals TLR7 dynamics underlying antagonism

Nature Communications
2020-10-15 | Journal article
Contributors: Shingo Tojo; Zhikuan Zhang; Hiroyuki Matsui; Masahiro Tahara; Mitsunori Ikeguchi; Mami Kochi; Mami Kamada; Hideki Shigematsu; Akihisa Tsutsumi; Naruhiko Adachi et al.
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Crossref
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HCV IRES Captures an Actively Translating 80S Ribosome

Molecular Cell
2019 | Journal article
EID:

2-s2.0-85067277551

Part of ISSN: 10974164 10972765
Contributors: Yokoyama, T.; Machida, K.; Iwasaki, W.; Shigeta, T.; Nishimoto, M.; Takahashi, M.; Sakamoto, A.; Yonemochi, M.; Harada, Y.; Shigematsu, H. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging

Virology
2019 | Journal article
EID:

2-s2.0-85063113122

Part of ISSN: 10960341 00426822
Contributors: Takizawa, N.; Ogura, Y.; Fujita, Y.; Noda, T.; Shigematsu, H.; Hayashi, T.; Kurokawa, K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22

Nature Communications
2018 | Journal article
EID:

2-s2.0-85045681081

Part of ISSN: 20411723
Contributors: Yamagata, A.; Miyazaki, Y.; Yokoi, N.; Shigematsu, H.; Sato, Y.; Goto-Ito, S.; Maeda, A.; Goto, T.; Sanbo, M.; Hirabayashi, M. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

Journal of Cell Biology
2018-12-03 | Journal article
Contributors: Tomohiro Shima; Manatsu Morikawa; Junichi Kaneshiro; Taketoshi Kambara; Shinji Kamimura; Toshiki Yagi; Hiroyuki Iwamoto; Sotaro Uemura; Hideki Shigematsu; Mikako Shirouzu et al.
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Crossref
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Structural insight into microtubule stabilization and kinesin inhibition by Tau family MAPs

Journal of Cell Biology
2018-12-03 | Journal article
Contributors: Hideki Shigematsu; Tsuyoshi Imasaki; Chihiro Doki; Takuya Sumi; Mari Aoki; Tomomi Uchikubo-Kamo; Ayako Sakamoto; Kiyotaka Tokuraku; Mikako Shirouzu; Ryo Nitta
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Crossref
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Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G

PLoS ONE
2017 | Journal article
EID:

2-s2.0-85019957711

Part of ISSN: 19326203
Contributors: Iwakura, N.; Yokoyama, T.; Quaglia, F.; Mitsuoka, K.; Mio, K.; Shigematsu, H.; Shirouzu, M.; Kaji, A.; Kaji, H.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Crystallization and X-ray analysis of 23 nm virus-like particles from Norovirus Chiba strain

Acta Crystallographica Section F:Structural Biology Communications
2017 | Journal article
EID:

2-s2.0-85031012487

Part of ISSN: 2053230X
Contributors: Hasegawa, K.; Someya, Y.; Shigematsu, H.; Kimura-Someya, T.; Nuemket, N.; Kumasaka, T.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Dynamic functional assembly of the Torsin AAA+ ATPase and its modulation by LAP1

Molecular Biology of the Cell
2017 | Journal article
EID:

2-s2.0-85031294316

Part of ISSN: 19394586 10591524
Contributors: Chase, A.R.; Laudermilch, E.; Wang, J.; Shigematsu, H.; Yokoyama, T.; Schlieker, C.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structural basis for CRMP2-induced axonal microtubule formation

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85028940316

Part of ISSN: 20452322
Contributors: Niwa, S.; Nakamura, F.; Tomabechi, Y.; Aoki, M.; Shigematsu, H.; Matsumoto, T.; Yamagata, A.; Fukai, S.; Hirokawa, N.; Goshima, Y. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structure of the complete elongation complex of RNA polymerase II with basal factors

Science
2017-09 | Journal article
Contributors: Haruhiko Ehara; Takeshi Yokoyama; Hideki Shigematsu; Shigeyuki Yokoyama; Mikako Shirouzu; Shun-ichi Sekine
Source: check_circle
Crossref
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Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs

Nucleic Acids Research
2016 | Journal article
EID:

2-s2.0-84992208872

Part of ISSN: 13624962 03051048
Contributors: Yip, W.S.V.; Shigematsu, H.; Taylor, D.W.; Baserga, S.J.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Motility and microtubule depolymerization mechanisms of the kinesin-8 motor, KIF19A

eLife
2016 | Journal article
EID:

2-s2.0-84989311472

Part of ISSN: 2050084X
Contributors: Wang, D.; Nitta, R.; Morikawa, M.; Yajima, H.; Inoue, S.; Shigematsu, H.; Kikkawa, M.; Hirokawa, N.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Pseudoatomic Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Reveals the Intermeshing Cogwheel-like Interaction between AcrA and TolC

Structure
2016 | Journal article
EID:

2-s2.0-84954305043

Part of ISSN: 18784186 09692126
Contributors: Jeong, H.; Kim, J.-S.; Song, S.; Shigematsu, H.; Yokoyama, T.; Hyun, J.; Ha, N.-C.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Self-assembly of size-controlled liposomes on DNA nanotemplates

Nature Chemistry
2016 | Journal article
EID:

2-s2.0-84964553510

Part of ISSN: 17554349 17554330
Contributors: Yang, Y.; Wang, J.; Shigematsu, H.; Xu, W.; Shih, W.M.; Rothman, J.E.; Lin, C.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Statistical modeling and removal of lipid membrane projections for cryo-EM structure determination of reconstituted membrane proteins

Journal of Structural Biology
2016 | Journal article
EID:

2-s2.0-84958109785

Part of ISSN: 10958657 10478477
Contributors: Jensen, K.H.; Brandt, S.S.; Shigematsu, H.; Sigworth, F.J.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility

Structure
2016 | Journal article
EID:

2-s2.0-84979976469

Part of ISSN: 18784186 09692126
Contributors: Yamagishi, M.; Shigematsu, H.; Yokoyama, T.; Kikkawa, M.; Sugawa, M.; Aoki, M.; Shirouzu, M.; Yajima, J.; Nitta, R.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structure of a group II intron in complex with its reverse transcriptase

Nature Structural and Molecular Biology
2016 | Journal article
EID:

2-s2.0-84965058797

Part of ISSN: 15459985 15459993
Contributors: Qu, G.; Kaushal, P.S.; Wang, J.; Shigematsu, H.; Piazza, C.L.; Agrawal, R.K.; Belfort, M.; Wang, H.-W.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Cryo-electron microscopic study of the enzymatic mechanism of the RNA 2'-O-methyltransferase Box C\D sRNP

Microscopy and Microanalysis
2014 | Journal article
EID:

2-s2.0-84927919169

Part of ISSN: 14358115 14319276
Contributors: Yip, W.S.V.; Shigematsu, H.; Taylor, D.W.; Wang, H.-W.; Baserga, S.J.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84900327289

Part of ISSN: 19326203
Contributors: Shigematsu, H.; Iida, K.; Nakano, M.; Chaudhuri, P.; Iida, H.; Nagayama, K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Noise models and cryo-EM drift correction with a direct-electron camera

Ultramicroscopy
2013 | Journal article
EID:

2-s2.0-84880273391

Part of ISSN: 03043991 18792723
Contributors: Shigematsu, H.; Sigworth, F.J.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Reversible assembly of stacked membrane nanodiscs with reduced dimensionality and variable periodicity

Journal of the American Chemical Society
2013 | Journal article
EID:

2-s2.0-84874882111

Part of ISSN: 00027863 15205126
Contributors: Beales, P.A.; Geerts, N.; Inampudi, K.K.; Shigematsu, H.; Wilson, C.J.; Vanderlick, T.K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Substrate-specific structural rearrangements of human Dicer

Nature Structural and Molecular Biology
2013 | Journal article
EID:

2-s2.0-84878905534

Part of ISSN: 15459993 15459985
Contributors: Taylor, D.W.; Ma, E.; Shigematsu, H.; Cianfrocco, M.A.; Noland, C.L.; Nagayama, K.; Nogales, E.; Doudna, J.A.; Wang, H.-W.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Using DNA-driven assembled phospholipid nanodiscs as a scaffold for gold nanoparticle patterning

Langmuir
2013 | Journal article
EID:

2-s2.0-84886628187

Part of ISSN: 15205827 07437463
Contributors: Geerts, N.; Schreck, C.F.; Beales, P.A.; Shigematsu, H.; O'Hern, C.S.; Vanderlick, T.K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Zernike phase contrast cryo-electron tomography of sodium-driven flagellar hook-basal bodies from Vibrio alginolyticus

Journal of Structural Biology
2011 | Journal article
EID:

2-s2.0-78649908289

Part of ISSN: 10478477 10958657
Contributors: Hosogi, N.; Shigematsu, H.; Terashima, H.; Homma, M.; Nagayama, K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

A 3.5-nm structure of rat TRPV4 cation channel revealed by zernike phase-contrast cryoelectron microscopy

Journal of Biological Chemistry
2010 | Journal article
EID:

2-s2.0-77951248588

Part of ISSN: 00219258 1083351X
Contributors: Shigematsu, H.; Sokabe, T.; Danev, R.; Tominaga, M.; Nagayama, K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

DNA-induced aggregation and fusion of phosphatidylcholine liposomes in the presence of multivalent cations observed by the Cryo-TEM technique

Journal of Membrane Biology
2009 | Journal article
EID:

2-s2.0-58549107990

Part of ISSN: 00222631
Contributors: Kuvichkin, V.V.; Danev, R.S.; Shigematsu, H.; Nagayama, K.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Expression of the extracellular region of the human interleukin-4 receptor α chain and interleukin-13 receptor α1 chain by a silkworm-baculovirus system

Protein Expression and Purification
2008 | Journal article
EID:

2-s2.0-43449088501

Part of ISSN: 10465928
Contributors: Honjo, E.; Shoyama, Y.; Tamada, T.; Shigematsu, H.; Hatanaka, T.; Kanaji, S.; Arima, K.; Ito, Y.; Izuhara, K.; Kuroki, R.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

IgG binding kinetics to oligo B protein A domains on lipid layers immobilized on a 27 MHz quartz-crystal microbalance

Journal of Molecular Recognition
2007 | Journal article
EID:

2-s2.0-34248574359

Part of ISSN: 09523499 10991352
Contributors: Mitomo, H.; Shigematsu, H.; Kobatake, E.; Furusawa, H.; Okahata, Y.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier

Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

Proceedings of the National Academy of Sciences of the United States of America
2004 | Journal article
EID:

2-s2.0-10744223059

Part of ISSN: 00278424
Contributors: Feese, M.D.; Tamada, T.; Kato, Y.; Maeda, Y.; Hirose, M.; Matsukura, Y.; Shigematsu, H.; Muto, T.; Matsumoto, A.; Watarai, H. et al.
Source: Self-asserted source
Hideki Shigematsu via Scopus - Elsevier
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