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Employment (1)

BeiGene (China): Beijing, CN

Employment
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yunhang guo

Education and qualifications (1)

Beijing Normal University: Beijing, Beijing, CN

Education
Source: Self-asserted source
yunhang guo

Works (4)

Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2

Journal of Medicinal Chemistry
2024-05-23 | Journal article
DOI: 10.1021/acs.jmedchem.4c00027
Contributors: Yunhang Guo; Hai Xue; Nan Hu; Ye Liu; Hanzi Sun; Desheng Yu; Ling Qin; Gongyin Shi; Fan Wang; Lei Xin et al.
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Sonrotoclax overcomes BCL2 G101V mutation–induced venetoclax resistance in preclinical models of hematologic malignancy

Blood
2024-05-02 | Journal article
DOI: 10.1182/blood.2023019706
Contributors: Jiuyang Liu; Shuran Li; Qin Wang; Yingcai Feng; Haimei Xing; Xuefei Yang; Ying Guo; Yunhang Guo; Hanzi Sun; Xiaoxin Liu et al.
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Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases

Journal of Medicinal Chemistry
2023-03-23 | Journal article
DOI: 10.1021/acs.jmedchem.2c01938
Contributors: Yunhang Guo; Nan Hu; Ye Liu; Wei Zhang; Desheng Yu; Gongyin Shi; Bo Zhang; Longbo Yin; Min Wei; Xi Yuan et al.
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Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Journal of Medicinal Chemistry
2019-09-12 | Journal article
DOI: 10.1021/acs.jmedchem.9b00687
Contributors: Yunhang Guo; Ye Liu; Nan Hu; Desheng Yu; Changyou Zhou; Gongyin Shi; Bo Zhang; Min Wei; Junhua Liu; Lusong Luo et al.
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Peer review (1 review for 1 publication/grant)

Review activity for Journal of medicinal chemistry. (1)
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