Personal information

Activities

Employment (1)

Nathan S Kline Institute: Orangeburg, NY, US

2007 to present (Dementia Research)
Employment
Source: Self-asserted source
Helen Scharfman

Education and qualifications (2)

Uniformed Services University of the Health Sciences: Bethesda, MD, US

1981 to 1986 (Pharmacology)
Education
Source: Self-asserted source
Helen Scharfman

Vassar College: Poughkeepsie, NY, US

1977 to 1981 (Biopsychology)
Education
Source: Self-asserted source
Helen Scharfman

Works (19)

Field EPSPs of Dentate Gyrus Granule Cells Studied by Selective Optogenetic Activation of Hilar Mossy Cells in Hippocampal Slices

Hippocampus
2025-01 | Journal article
Contributors: Hannah L. Bernstein; Yi‐Ling Lu; Justin J. Botterill; Áine M. Duffy; John J. LaFrancois; Helen E. Scharfman
Source: check_circle
Crossref

Towards an Understanding of the Dentate Gyrus Hilus

Hippocampus
2025-01 | Journal article
Contributors: Helen E. Scharfman
Source: check_circle
Crossref

Increasing adult-born neurons protects mice from epilepsy

eLife
2024-10-24 | Journal article
Contributors: Swati Jain; John J LaFrancois; Kasey Gerencer; Justin J Botterill; Meghan Kennedy; Chiara Criscuolo; Helen E Scharfman
Source: check_circle
Crossref

Increasing adult-born neurons protects mice from epilepsy

eLife
2024-10-24 | Journal article
Contributors: Swati Jain; John J LaFrancois; Kasey Gerencer; Justin J Botterill; Meghan Kennedy; Chiara Criscuolo; Helen E Scharfman
Source: check_circle
Crossref

Increasing adult neurogenesis protects mice from epilepsy

2024-08-20 | Preprint
Contributors: Swati Jain; John J LaFrancois; Kasey Gerencer; Justin J Botterill; Meghan Kennedy; Chiara Criscuolo; Helen E Scharfman
Source: check_circle
Crossref

Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

eLife
2024-06-21 | Journal article
Contributors: Elissavet Chartampila; Karim S Elayouby; Paige Leary; John J LaFrancois; David Alcantara-Gonzalez; Swati Jain; Kasey Gerencer; Justin J Botterill; Stephen D Ginsberg; Helen E Scharfman
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Crossref

Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease

eLife
2024-06-21 | Journal article
Contributors: Elissavet Chartampila; Karim S Elayouby; Paige Leary; John J LaFrancois; David Alcantara-Gonzalez; Swati Jain; Kasey Gerencer; Justin J Botterill; Stephen D Ginsberg; Helen E Scharfman
Source: check_circle
Crossref

Increasing adult neurogenesis protects mice from epilepsy

2023-10-04 | Preprint
Contributors: Swati Jain; John J. LaFrancois; Kasey Gerencer; Justin J. Botterill; Meghan Kennedy; Chiara Criscuolo; Helen E. Scharfman
Source: check_circle
Crossref

Increasing adult-born neurons protects mice from epilepsy

2023-07-10 | Preprint
Contributors: Swati Jain; John J. LaFrancois; Kasey Gerencer; Justin J. Botterill; Meghan Kennedy; Chiara Criscuolo; Helen E. Scharfman
Source: check_circle
Crossref

Interictal Spikes in Alzheimer’s Disease: Preclinical Evidence for Dominance of the Dentate Gyrus and Cholinergic Control by Medial Septum

2023-04-24 | Preprint
Contributors: Christos Panagiotis Lisgaras; Helen E. Scharfman
Source: check_circle
Crossref

High‐frequency oscillations (250–500 Hz) in animal models of Alzheimer's disease and two animal models of epilepsy

Epilepsia
2023-01 | Journal article
Contributors: Christos Panagiotis Lisgaras; Helen E. Scharfman
Source: check_circle
Crossref

Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice

The Journal of Neuroscience
2021-03-17 | Journal article
Contributors: Justin J. Botterill; K. Yaragudri Vinod; Kathleen J. Gerencer; Cátia M. Teixeira; John J. LaFrancois; Helen E. Scharfman
Source: check_circle
Crossref

Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer’s disease neuropathology and atypical effects of the cholinergic antagonist atropine

2020-10-02 | Preprint
Contributors: David Alcantara-Gonzalez; Elissavet Chartampila; Helen E Scharfman
Source: check_circle
Crossref

Novelty and Novel Objects Increase c-Fos Immunoreactivity in Mossy Cells in the Mouse Dentate Gyrus

Neural Plasticity
2019-08-27 | Journal article
Contributors: Hannah L. Bernstein; Yi-Ling Lu; Justin J. Botterill; Helen E. Scharfman
Source: check_circle
Crossref

The Dentate Gyrus and Temporal Lobe Epilepsy: An “Exciting” Era

Epilepsy Currents
2019-07 | Journal article
Contributors: Helen E. Scharfman
Source: check_circle
Crossref

A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75NTR-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal DeathIn VitroandIn Vivo

eneuro
2018-01 | Journal article
Contributors: Shayri G. Greenwood; Laura Montroull; Marta Volosin; Helen E. Scharfman; Kenneth K. Teng; Matthew Light; Risa Torkin; Fredrick Maxfield; Barbara L. Hempstead; Wilma J. Friedman
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Crossref

Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats

Brain Structure and Function
2017-12-27 | Journal article
Contributors: Alejandra Magagna-Poveda; Jillian N. Moretto; Helen E. Scharfman
Source: check_circle
Crossref

Acute restraint stress decreases c-fos immunoreactivity in hilar mossy cells of the adult dentate gyrus

Brain Structure and Function
2017-07-11 | Journal article
Contributors: Jillian N. Moretto; Áine M. Duffy; Helen E. Scharfman
Source: check_circle
Crossref

Opioid Receptor-Dependent Sex Differences in Synaptic Plasticity in the Hippocampal Mossy Fiber Pathway of the Adult Rat

The Journal of Neuroscience
2015-01-28 | Journal article
Contributors: Lauren C. Harte-Hargrove; Ada Varga-Wesson; Aine M. Duffy; Teresa A. Milner; Helen E. Scharfman
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Crossref

Peer review (19 reviews for 12 publications/grants)

Review activity for Chaos. (2)
Review activity for eLife (1)
Review activity for ENeuro. (1)
Review activity for Frontiers in neuroendocrinology. (1)
Review activity for iScience. (3)
Review activity for JoVE. (1)
Review activity for Neurobiology of aging. (1)
Review activity for Neurobiology of disease. (3)
Review activity for Neurobiology of stress. (3)
Review activity for Progress in neurobiology. (1)
Review activity for Science. (1)
Review activity for The Innovation. (1)