Personal information

Activities

Employment (6)

Massachusetts General Hospital: Boston, MA, US

2017-08 to present | Graduate Researcher (Cardiovascular Research Center)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Broad Institute: Cambridge, MA, US

2017-08 to present | Postdoctoral Research Fellow (Medical and Population Genetics)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Massachusetts Eye and Ear: MA, MA, US

2022-06 to 2026-06 | Ophthalmology Resident (Department of Ophthalmology)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Yale University: New Haven, CT, US

2017-08 to 2022-05 | Graduate Researcher (MD/PhD student) (Computational Biology & Bioinformatics)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Broad Institute: Cambridge, MA, US

2015-09 to 2017-09 | Associate Computational Biologist (Medical and Population Genetics)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Roche: Basel, CH

2014-06 to 2017-06 | Consultant, Visiting Scientist, Intern in Disease Modeling (Clinical Pharmacology, Ophthalmology)
Employment
Source: Self-asserted source
Seyedeh M. Zekavat

Education and qualifications (2)

Yale University School of Medicine: New Haven, CT, US

2017-06 to present | MD/PhD (Computational Biology & Bioinformatics)
Education
Source: Self-asserted source
Seyedeh M. Zekavat

Massachusetts Institute of Technology School of Engineering: Cambridge, MA, US

2011-08 to 2015-06 | Bachelors of Science (Biological Engineering)
Education
Source: Self-asserted source
Seyedeh M. Zekavat

Funding (3)

Dissecting the impact of clonal hematopoiesis on atherosclerosis using multiscale 'omics

2019-08 to 2023-08 | Grant
National Institutes of Health (Md., Md., US)
GRANT_NUMBER:

1F30HL149180-01

Source: Self-asserted source
Seyedeh M. Zekavat

2017 Paul & Daisy Soros Fellow

2017-07 to 2019-07 | Award
Paul and Daisy Soros Fellowships for New Americans (New York, NY, US)
Source: Self-asserted source
Seyedeh M. Zekavat

In-silico modeling of retinal cholesterol dynamics: Insights into the pathophysiology of dry Age-related Macular Degeneration

2014 to 2015 | Grant
Massachusetts Institute of Technology (Cambridge, MA, US)
Source: Self-asserted source
Seyedeh M. Zekavat

Works (37)

Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.

Apollo - University of Cambridge Repository
2022-05-09 | Journal article
Contributors: Tetsushi Nakao; Alexander Bick; Margaret A Taub; Seyedeh M. Zekavat; Md Mesbah Uddin; Abhishek Niroula; Cara; John Lane; Michael Honigberg; Joshua Weinstock et al.
Source: check_circle
DataCite

Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease.

JAMA
2019-11-18 | Journal article
Source: Self-asserted source
Seyedeh M. Zekavat

Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy.

Journal of the American College of Cardiology
2019-11-11 | Journal article
Source: Self-asserted source
Seyedeh M. Zekavat

Rare Genetic Variants Associated With Sudden Cardiac Death in Adults.

Journal of the American College of Cardiology
2019-11-11 | Journal article
Source: Self-asserted source
Seyedeh M. Zekavat

Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease.

Arteriosclerosis, thrombosis, and vascular biology
2019-06 | Journal article
Contributors: Zekavat SM; Aragam K; Emdin C; Khera AV; Klarin D; Zhao H; Natarajan P
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Genetic Link Between Arterial Stiffness and Atrial Fibrillation.

Circulation. Genomic and precision medicine
2019-06 | Journal article
Contributors: Zekavat SM; Roselli C; Hindy G; Lubitz SA; Ellinor PT; Zhao H; Natarajan P
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction.

Circulation
2019-03 | Journal article
Contributors: Khera AV; Chaffin M; Zekavat SM; Collins RL; Roselli C; Natarajan P; Lichtman JH; D'Onofrio G; Mattera J; Dreyer R et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

A statistical framework for cross-tissue transcriptome-wide association analysis.

Nature genetics
2019-02 | Journal article
Contributors: Hu Y; Li M; Lu Q; Weng H; Wang J; Zekavat SM; Yu Z; Li B; Gu J; Muchnik S et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

Nature Communications
2018 | Journal article
WOSUID:

WOS:000430674000002

Contributors: Emdin, Connor A.; Khera, Amit V.; Chaffin, Mark; Klarin, Derek; Natarajan, Pradeep; Aragam, Krishna; Haas, Mary; Bick, Alexander; Zekavat, Seyedeh M.; Nomura, Akihiro et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

Nature communications
2018 | Journal article
WOSUID:

MEDLINE:29973585

Contributors: Zekavat, Seyedeh M; Ruotsalainen, Sanni; Handsaker, Robert E; Alver, Maris; Bloom, Jonathan; Poterba, Timothy; Seed, Cotton; Ernst, Jason; Chaffin, Mark; Engreitz, Jesse et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling

Circulation
2018 | Journal article
WOSUID:

WOS:000422767000003

Contributors: Emdin, Connor A.; Khera, Amit V.; Klarin, Derek; Natarajan, Pradeep; Zekavat, Seyedeh M.; Nomura, Akihiro; Haas, Mary; Aragam, Krishna; Ardissino, Diego; Wilson, James G. et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

American Journal of Human Genetics
2018 | Journal article
WOSUID:

WOS:000434946200016

Contributors: Ganna, Andrea; Satterstrom, F. Kyle; Zekavat, Seyedeh M.; Das, Indraniel; Kurki, Mitja, I; Churchhouse, Claire; Alfoldi, Jessica; Martin, Alicia R.; Havulinna, Aki S.; Byrnes, Andrea et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.

Diabetes
2018-11 | Journal article
Contributors: Emdin CA; Khera AV; Aragam K; Haas M; Chaffin M; Klarin D; Natarajan P; Bick A; Zekavat SM; Nomura A et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Genetic Association of Arterial Stiffness Index with Blood Pressure and Coronary Artery Disease

2018-10 | Other
OTHER-ID:

PPR59985

Contributors: Zekavat SM; Haas M; Aragam K; Emdin C; Khera AV; Klarin D; Zhao H; Natarajan P
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia.

Genetics in medicine : official journal of the American College of Medical Genetics
2018-10 | Journal article
Contributors: Alver M; Palover M; Saar A; Läll K; Zekavat SM; Tõnisson N; Leitsalu L; Reigo A; Nikopensius T; Ainla T et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.

Nature communications
2018-08 | Journal article
Contributors: Natarajan P; Peloso GM; Zekavat SM; Montasser M; Ganna A; Chaffin M; Khera AV; Zhou W; Bloom JM; Engreitz JM et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

Nature communications
2018-08 | Journal article
Contributors: Zekavat SM; Ruotsalainen S; Handsaker RE; Alver M; Bloom J; Poterba T; Seed C; Ernst J; Chaffin M; Engreitz J et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

A statistical framework for cross-tissue transcriptome-wide association analysis

2018-03 | Other
OTHER-ID:

PPR17202

Contributors: Hu Y; Li M; Lu Q; Weng H; Wang J; Zekavat SM; Yu Z; Li B; Muchnik S; Shi Y et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

A computational model of 1,5-AG dynamics during pregnancy.

Physiological reports
2017 | Journal article
WOSUID:

MEDLINE:28821595

Contributors: Zekavat, Seyedeh M; Butkovich, Slava; Young, Grace J; Nathan, David M; Petrasek, Danny
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

Cell
2017 | Journal article
WOSUID:

WOS:000406462400011

Contributors: Gupta, Rajat M.; Hadaya, Joseph; Trehan, Aditi; Zekavat, Seyedeh M.; Roselli, Carolina; Klarin, Derek; Emdin, Connor A.; Hilvering, Catharina R. E.; Bianchi, Valerio; Mueller, Christian et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Acquired Vitamin K Deficiency as Unusual Cause of Bleeding Tendency in Adults: A Case Report of a Nonhospitalized Student Presenting with Severe Menorrhagia.

Case reports in obstetrics and gynecology
2017 | Journal article
WOSUID:

MEDLINE:28928999

Contributors: Zekavat, Omid Reza; Fathpour, Gholamreza; Haghpanah, Sezaneh; Dehghani, Seyed Javad; Zekavat, Maryam; Shakibazad, Nader
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

An in silico model of retinal cholesterol dynamics (RCD model): insights into the pathophysiology of dry AMD

Journal of Lipid Research
2017 | Journal article
WOSUID:

WOS:000404576500006

Contributors: Zekavat, Seyedeh Maryam; Lu, James; Maugeais, Cyrille; Mazer, Norman A.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

Journal of the American College of Cardiology
2017 | Journal article
WOSUID:

WOS:000399292100009

Contributors: Stitziel, Nathan O.; Khera, Amit V.; Wang, Xiao; Bierhals, Andrew J.; Vourakis, A. Christina; Sperry, Alexandra E.; Natarajan, Pradeep; Klarin, Derek; Emdin, Connor A.; Zekavat, Seyedeh M. et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Proceedings of the National Academy of Sciences of the United States of America
2017 | Journal article
WOSUID:

WOS:000392095800009

Contributors: Guo, Michael H.; Nandakumar, Satish K.; Ulirsch, Jacob C.; Zekavat, Seyedeh M.; Buenrostro, Jason D.; Natarajan, Pradeep; Salem, Rany M.; Chiarle, Roberto; Mitt, Mario; Kals, Mart et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease

Jama-Journal of the American Medical Association
2017 | Journal article
WOSUID:

WOS:000394870900017

Contributors: Emdin, Connor A.; Khera, Amit V.; Natarajan, Pradeep; Klarin, Derek; Zekavat, Seyedeh M.; Hsiao, Allan J.; Kathiresan, Sekar
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

Circulation Research
2017 | Journal article
WOSUID:

WOS:000403914900012

Contributors: Nomura, Akihiro; Won, Hong-Hee; Khera, Amit V.; Takeuchi, Fumihiko; Ito, Kaoru; McCarthy, Shane; Emdin, Connor A.; Klarin, Derek; Natarajan, Pradeep; Zekavat, Seyedeh M. et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

2017-11 | Other
OTHER-ID:

PPR23374

Contributors: Zekavat SM; Ruotsalainen S; Handsaker RE; Alver M; Bloom J; Poterba T; Seed C; Ernst J; Chaffin M; Engreitz J et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

2017-11 | Other
OTHER-ID:

PPR23419

Contributors: Natarajan P; Peloso GM; Zekavat SM; Montasser M; Ganna A; Chaffin M; Khera AV; Zhao W; Bloom JM; Engreitz JM et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.

Apollo - University of Cambridge Repository
2017-06 | Journal article
Contributors: Akihiro Nomura; Hong-Hee Won; Amit V Khera; Fumihiko Takeuchi; Kaoru Ito; Shane McCarthy; Connor A Emdin; Derek Klarin; Pradeep Natarajan; Seyedeh M. Zekavat et al.
Source: check_circle
DataCite

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

2017-06 | Other
OTHER-ID:

PPR9009

Contributors: Ganna A; Satterstrom KF; Zekavat SM; Das I; Kurki MI; Churchhouse C; Alfoldi J; Martin AR; Havulinna AS; Byrnes A et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels

Journal of the American College of Cardiology
2016 | Journal article
WOSUID:

WOS:000392990600007

Contributors: Emdin, Connor A.; Khera, Amit V.; Natarajan, Pradeep; Klarin, Derek; Won, Hong-Hee; Peloso, Gina M.; Stitziel, Nathan O.; Nomura, Akihiro; Zekavat, Seyedeh M.; Bick, Alexander G. et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

Nature Neuroscience
2016 | Journal article
WOSUID:

WOS:000389011900014

Contributors: Ganna, Andrea; Genovese, Giulio; Howrigan, Daniel P.; Byrnes, Andrea; Kurki, Mitja I.; Zekavat, Seyedeh M.; Whelan, Christopher W.; Kals, Mart; Nivard, Michel G.; Bloemendal, Alex et al.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

2016-08 | Other
OTHER-ID:

PPR29511

Contributors: Guo M; Nandakumar SK; Ulirsch JC; Zekavat SM; Buenrostro JD; Natarajan P; Salem R; Chiarle R; Mitt M; Kals M et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

2016-06 | Other
OTHER-ID:

PPR30018

Contributors: Ganna A; Genovese G; Howrigan DP; Byrnes A; Kurki M; Zekavat SM; Whelan CW; Kals M; Nivard MG; Bloemendal A et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Europe PubMed Central

In-silico model of retinal cholesterol dynamics: Insights into the pathophysiology of dry AMD

Investigative Ophthalmology & Visual Science
2015 | Journal article
WOSUID:

WOS:000362891102193

Contributors: Zekavat, Seyedeh Maryam; Lu, James; Maugeais, Cyrille; Mazer, Norman
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Mathematical framework for activity-based cancer biomarkers

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
WOSUID:

WOS:000363130900032

Contributors: Kwong, Gabriel A.; Dudani, Jaideep S.; Carrodeguas, Emmanuel; Mazumdar, Eric V.; Zekavat, Seyedeh M.; Bhatia, Sangeeta N.
Source: Self-asserted source
Seyedeh M. Zekavat via ResearcherID

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes

Other
Contributors: Seyedeh Maryam Zekavat; Saman Doroodgar Jorshery; Yusrah Shweikh; Katrin Horn; Franziska G. Rauscher; Sayuri Sekimitsu; Satoshi Kayoma; Yixuan Ye; Vineet Raghu; Hongyu Zhao et al.
Source: Self-asserted source
Seyedeh M. Zekavat via Crossref Metadata Search