Personal information

France

Activities

Employment (1)

CNRS Délégation Alsace: Strasbourg, Alsace, FR

1992-10-01 to present | Directeur de Recherche 1ere classe (INSB)
Employment
Source: Self-asserted source
Norbert GHYSELINCK

Education and qualifications (2)

Université de Strasbourg: Strasbourg, Alsace, FR

2003 to 2003 | HDR
Education
Source: Self-asserted source
Norbert GHYSELINCK

Université Blaise Pascal: Clermont-Ferrand, Auvergne, FR

1988 to 1991 | PhD
Education
Source: Self-asserted source
Norbert GHYSELINCK

Funding (6)

Retinoic acid and differentiation of gametes – ARDIGAM

2022-09-21 to 2025-09-20 | Grant
Agence Nationale de la Recherche (Paris, FR)
GRANT_NUMBER: ANR-22-CE14-0017
Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard

Retinoic acid for germ cell differentiation and meiosis – ARDIGERM

2020-10-21 to 2024-10-20 | Grant
Agence Nationale de la Recherche (Paris, FR)
GRANT_NUMBER: ANR-20-CE14-0022
Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard

DECIPHERING NON-CANONICAL PATHWAYS CONTROLLED BY RETINOIC ACID IN VIVO USING SERTOLI CELLS AS A MODEL – ARESSERC

2016-09-21 to 2019-09-20 | Grant
Agence Nationale de la Recherche (Paris, FR)
GRANT_NUMBER: ANR-16-CE14-0017
Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard

Retinoic acid and the fate of germ cells

2014-01-01 to 2017-12-31 | Grant
French National Research Agency (Paris, FR)
GRANT_NUMBER: ANR-13-BSV2-0017
Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard
grade
Preferred source (of 2)‎

Retinoic acid receptor-mediated gene repression, from molecular basis to physiological significance

Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard

Molecular mechanisms governing the meiosis entry in mammals

Source: Self-asserted source
Norbert GHYSELINCK via DimensionsWizard

Works (50 of 173)

Items per page:
Page 1 of 4

Meiosis and retinoic acid in the mouse fetal gonads: An unforeseen twist

2025 | Book chapter
Contributors: Giulia Perrotta; Diana Condrea; Norbert B. Ghyselinck
Source: check_circle
Crossref

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis.

Development (Cambridge, England)
2023-12 | Journal article
Contributors: Souali-Crespo S; Condrea D; Vernet N; Féret B; Klopfenstein M; Grandgirard E; Alunni V; Cerciat M; Jung M; Mayere C et al.
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

Biomedicines
2023-01-12 | Journal article
Contributors: Marius Teletin; Manuel Mark; Olivia Wendling; Nadège Vernet; Betty Féret; Muriel Klopfenstein; Yann Herault; Norbert B. Ghyselinck
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Why serology just is not enough: Strategic parvovirus risk assessment using a novel qPCR assay

Laboratory Animals
2022-08 | Journal article
Contributors: Ann-Kathrin Iwantschenko; Florian Roegener; Wiebke Garrels; Martina Dorsch; Wiebke Köhl; Christian Riehle; Norbert Ghyselinck; Betty Féret; Nils-Holger Zschemisch; André Bleich et al.
Source: check_circle
Crossref

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad.

Science advances
2022-05 | Journal article
Contributors: Mayère C; Regard V; Perea-Gomez A; Bunce C; Neirijnck Y; Djari C; Bellido-Carreras N; Sararols P; Reeves R; Greenaway S et al.
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

Retinoic Acid Receptor Alpha Is Essential in Postnatal Sertoli Cells but Not in Germ Cells

Cells
2022-03-04 | Journal article
Contributors: Diana Condrea; Sirine Souali-Crespo; Betty Féret; Muriel Klopfenstein; Sylvain Faisan; Manuel Mark; Norbert B. Ghyselinck; Nadège Vernet
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.

Cell stem cell
2021-10 | Journal article
Contributors: Schönberger K; Obier N; Romero-Mulero MC; Cauchy P; Mess J; Pavlovich PV; Zhang YW; Mitterer M; Rettkowski J; Lalioti ME et al.
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction.

eLife
2021-10 | Journal article
Contributors: Da Silva F; Jian Motamedi F; Weerasinghe Arachchige LC; Tison A; Bradford ST; Lefebvre J; Dolle P; Ghyselinck NB; Wagner KD; Schedl A
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

Biomedicines
2021-06-28 | Journal article
Contributors: Manuel Mark; Marius Teletin; Olivia Wendling; Jean-Luc Vonesch; Betty Féret; Yann Hérault; Norbert B. Ghyselinck
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

PLoS Biology
2020-11-17 | Journal article
Contributors: Glenda Evangelina Comai; Markéta Tesařová; Valerie Dupé; Muriel Rhinn; Pedro Vallecillo-García; Fabio da Silva; Betty Feret; Katherine Exelby; Pascal Dollé; Leif Carlsson et al.
Source: Self-asserted source
Norbert GHYSELINCK via HAL

Meiosis occurs normally in the fetal ovary of mice lacking all retinoic acid receptors

Science Advances
2020-05-22 | Journal article
Part of ISSN: 2375-2548
Source: Self-asserted source
Norbert GHYSELINCK

Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

Science Advances
2020-05-22 | Journal article
Contributors: Anne-Amandine Chassot; Morgane Le Rolle; Geneviève Jolivet; Isabelle Stevant; Jean-Marie Guigonis; Fabio Da Silva; Serge Nef; Eric Pailhoux; Andreas Schedl; Norbert B. Ghyselinck et al.
Source: check_circle
Crossref

Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling.

Scientific reports
2019-10-11 | Journal article
Source: Self-asserted source
Norbert GHYSELINCK

Retinoic acid signaling pathways

Development
2019-07-01 | Journal article
Contributors: Norbert B. Ghyselinck; Gregg Duester
Source: check_circle
Crossref

Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium.

Development (Cambridge, England)
2019-01-04 | Journal article
Source: Self-asserted source
Norbert GHYSELINCK

Retinoic acid improves nephrotoxic serum–induced glomerulonephritis through activation of podocyte retinoic acid receptor α

Kidney International
2017 | Journal article
Part of ISSN: 0085-2538
Contributors: Yan Dai; Anqun Chen; Ruijie Liu; Leyi Gu; Shuchita Sharma; Weijing Cai; Fadi Salem; David J. Salant; Jeffrey W. Pippin; Stuart J. Shankland et al.
Source: Self-asserted source
Norbert GHYSELINCK via Crossref Metadata Search

Roles of Retinoic Acid in Germ Cell Differentiation

Nuclear Receptors in Development and Disease
2017 | Other
Part of ISBN: 9780128021729
Part of ISSN: 0070-2153
Contributors: Marius Teletin; Nadège Vernet; Norbert B. Ghyselinck; Manuel Mark
Source: Self-asserted source
Norbert GHYSELINCK via Crossref Metadata Search

Acide rétinoïque et méiose : mythe ou réalité ?

Annales d'Endocrinologie
2017-09 | Journal article
Part of ISSN: 0003-4266
Contributors: N.B. Ghyselinck; M. Mark
Source: Self-asserted source
Norbert GHYSELINCK via Crossref Metadata Search

Constitutive WNT/CTNNB1 activation triggers spermatogonial stem cell proliferation and germ cell depletion

Developmental Biology
2017-06 | Journal article
Part of ISSN: 0012-1606
Contributors: Anne-Amandine Chassot; Morgane Le Rolle; Maxime Jourden; Maketo M. Taketo; Norbert B. Ghyselinck; Marie-Christine Chaboissier
Source: Self-asserted source
Norbert GHYSELINCK via Crossref Metadata Search

Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.

2017-03 | Journal article
Contributors: Minkina A; Lindeman RE; Gearhart MD; Chassot AA; Chaboissier MC; Ghyselinck NB; Bardwell VJ; Zarkower D
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

Endogenous retinoic acid signaling is required for maintenance and regeneration of cornea.

2017-01 | Journal article
Contributors: Kumar S; Dollé P; Ghyselinck NB; Duester G
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central
grade
Preferred source (of 2)‎

Hepatocytes Are the Principal Source of Circulating RBP4 in Mice.

2017-01 | Journal article
Contributors: Thompson SJ; Sargsyan A; Lee SA; Yuen JJ; Cai J; Smalling R; Ghyselinck N; Mark M; Blaner WS; Graham TE
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central

MEI4-a central player in the regulation of meiotic DNA double-strand break formation in the mouse

Journal of Cell Science
2015 | Journal article
WOSUID:

WOS:000354873100014

Contributors: Kumar, R.; Ghyselinck, N.; Ishiguro, K.; Watanabe, Y.; Kouznetsova, A.; Hoog, C.; Strong, E.; Schimenti, J.; Daniel, K.; Toth, A. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor

PLoS Genetics
2015 | Journal article
WOSUID:

WOS:000364401600009

Contributors: Gely-Pernot, Aurore; Raverdeau, Mathilde; Teletin, Marius; Vernet, Nadege; Feret, Betty; Klopfenstein, Muriel; Dennefeld, Christine; Davidson, Irwin; Benoit, Gerard; Mark, Manuel et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID
grade
Preferred source (of 2)‎

Role of retinoic acid receptor (RAR) signaling in post-natal male germ cell differentiation

Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms
2015 | Journal article
WOSUID:

WOS:000349272700003

Contributors: Mark, M.; Teletin, M.; Vernet, N.; Ghyselinck, N. B.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoic Acid Receptor Signaling in Post-Natal Male Germ Cell Differentiation

The Retinoids
2015-06 | Other
Part of ISBN: 9781118628003
Contributors: Manuel Mark; Norbert B. Ghyselinck
Source: Self-asserted source
Norbert GHYSELINCK via Crossref Metadata Search
grade
Preferred source (of 2)‎

DMRT1 Protects Male Gonadal Cells from Retinoid-Dependent Sexual Transdifferentiation

Developmental Cell
2014 | Journal article
WOSUID:

WOS:000337644700005

Contributors: Minkina, A.; Matson, C. K.; Lindeman, R. E.; Ghyselinck, N. B.; Bardwell, V. J.; Zarkower, D.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

FOXL2 Is a Female Sex-Determining Gene in the Goat

Current Biology
2014 | Journal article
WOSUID:

WOS:000331718900022

Contributors: Boulanger, L.; Pannetier, M.; Gall, L.; Allais-Bonnet, A.; Elzaiat, M.; Le Bourhis, D.; Daniel, N.; Richard, C.; Cotinot, C.; Ghyselinck, N. B. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

The STRA6 Receptor Is Essential for Retinol-binding Protein-induced Insulin Resistance but Not for Maintaining Vitamin A Homeostasis in Tissues Other Than the Eye

Journal of Biological Chemistry
2013 | Journal article
WOSUID:

WOS:000330612300021

Contributors: Berry, D. C.; Jacobs, H.; Marwarha, G.; Gely-Pernot, A.; O'Byrne, S. M.; DeSantis, D.; Klopfenstein, M.; Feret, B.; Dennefeld, C.; Blaner, W. S. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID
grade
Preferred source (of 2)‎

Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

Investigative Ophthalmology & Visual Science
2012 | Journal article
WOSUID:

WOS:000304864600059

Contributors: Ruiz, Alberto; Mark, Manuel; Jacobs, Hugues; Klopfenstein, Muriel; Hu, Jane; Lloyd, Marcia; Habib, Samer; Tosha, Chinatsu; Radu, Roxana A.; Ghyselinck, Norbert B. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex Reversals

Plos Genetics
2012 | Journal article
WOSUID:

WOS:000312905600058

Contributors: Lavery, Rowena; Chassot, Anne-Amandine; Pauper, Eva; Gregoire, Elodie P.; Klopfenstein, Muriel; de Rooij, Dirk G.; Mark, Manuel; Schedl, Andreas; Ghyselinck, Norbert B.; Chaboissier, Marie-Christine
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Transthyretin Blocks Retinol Uptake and Cell Signaling by the Holo-Retinol-Binding Protein Receptor STRA6

Molecular and Cellular Biology
2012 | Journal article
WOSUID:

WOS:000308748100005

Contributors: Berry, Daniel C.; Croniger, Colleen M.; Ghyselinck, Norbert B.; Noy, Noa
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID
grade
Preferred source (of 2)‎

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.

2012-10 | Journal article
Contributors: Raverdeau M; Gely-Pernot A; Féret B; Dennefeld C; Benoit G; Davidson I; Chambon P; Mark M; Ghyselinck NB
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central
grade
Preferred source (of 2)‎

Spermatogonia differentiation requires retinoic acid receptor γ.

2012-01 | Journal article
Contributors: Gely-Pernot A; Raverdeau M; Célébi C; Dennefeld C; Feret B; Klopfenstein M; Yoshida S; Ghyselinck NB; Mark M
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central
grade
Preferred source (of 2)‎

RA-RAR-beta counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression

Journal of Cell Biology
2011 | Journal article
WOSUID:

WOS:000292135400004

Contributors: Puttagunta, Radhika; Schmandke, Andre; Floriddia, Elisa; Gaub, Perrine; Fomin, Natalie; Ghyselinck, Norbert B.; Di Giovanni, Simone
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoic Acid Drives Aryl Hydrocarbon Receptor Expression and Is Instrumental to Dioxin-Induced Toxicity during Palate Development

Environmental Health Perspectives
2011 | Journal article
WOSUID:

WOS:000296785900026

Contributors: Jacobs, Hugues; Dennefeld, Christine; Feret, Betty; Viluksela, Matti; Hakansson, Helen; Mark, Manuel; Ghyselinck, Norbert B.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription

Cell Death and Differentiation
2011 | Journal article
WOSUID:

WOS:000289344200005

Contributors: Toth, K.; Sarang, Z.; Scholtz, B.; Brazda, P.; Ghyselinck, N.; Chambon, P.; Fesues, L.; Szondy, Z.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

2011-07 | Journal article
Contributors: Fernández-Miranda G; Trakala M; Martín J; Escobar B; González A; Ghyselinck NB; Ortega S; Cañamero M; Pérez de Castro I; Malumbres M
Source: Self-asserted source
Norbert GHYSELINCK via Europe PubMed Central
grade
Preferred source (of 2)‎

Retinoic Acid Receptor (RAR)-alpha Is Not Critically Required for Mediating Retinoic Acid Effects in the Developing Mouse Retina

Investigative Ophthalmology & Visual Science
2010 | Journal article
WOSUID:

WOS:000277846500060

Contributors: Cammas, Laura; Trensz, Frederic; Jellali, Abdeljalil; Ghyselinck, Norbert B.; Roux, Michel J.; Dolle, Pascal
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

A transcriptionally silent RXR alpha supports early embryonic morphogenesis and heart development

Proceedings of the National Academy of Sciences of the United States of America
2009 | Journal article
WOSUID:

WOS:000264278800041

Contributors: Mascrez, Benedicte; Ghyselinck, Norbert B.; Chambon, Pierre; Mark, Manuel
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

Journal of Cell Science
2009 | Journal article
WOSUID:

WOS:000268179400014

Contributors: Leclerc, Emilie A.; Huchenq, Anne; Mattiuzzo, Nicolas R.; Metzger, Daniel; Chambon, Pierre; Ghyselinck, Norbert B.; Serre, Guy; Jonca, Nathalie; Guerrin, Marina
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Corneodesmosin, an essential actor of the epidermis barrier and the hair follicle integrity

Journal of Investigative Dermatology
2009 | Journal article
WOSUID:

WOS:000263569500063

Contributors: Leclerc, E.; Jonca, N.; Huchenq, A.; Mattiuzzo, N.; Gazeilles, L.; Galliano, M. F.; Ghyselinck, N.; Metzger, D.; Chambon, P.; Guerrin, M. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Effects of vitamin A on spermatogenesis,Effets de la vitamineAsur la spermatogenèse

Medecine Therapeutique Medecine de la Reproduction, Gynecologie et Endocrinologie
2009 | Journal article
EID:

2-s2.0-67649949157

Contributors: Mark, M.; Ghyselinck, N.B.
Source: Self-asserted source
Norbert GHYSELINCK via Scopus - Elsevier

Function of retinoic acid receptors during embryonic development.

Nuclear receptor signaling
2009 | Journal article
WOSUID:

MEDLINE:19381305

Contributors: Mark, Manuel; Ghyselinck, Norbert B; Chambon, Pierre
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse

Developmental Biology
2009 | Journal article
WOSUID:

WOS:000265239100013

Contributors: Williams, Julie A.; Kondo, Naoki; Okabe, Takahiro; Takeshita, Nobuo; Pilchak, Diane M.; Koyama, Eiki; Ochiai, Takanaga; Jensen, Deborah; Chu, Mon-Li; Kane, Maureen A. et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis

Developmental Biology
2008 | Journal article
WOSUID:

WOS:000258262500015

Contributors: Matt, Nicolas; Ghyselinck, Norbert B.; Pellerin, Isabelle; Dupe, Valerie
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Modular patterning of structure and function of the striatum by retinoid receptor signaling

Proceedings of the National Academy of Sciences of the United States of America
2008 | Journal article
WOSUID:

WOS:000255841600046

Contributors: Liao, Wen-Lin; Tsai, Hsiu-Chao; Wang, Hsiao-Fang; Chang, Josephine; Lu, Kuan-Ming; Wu, Hsiao-Lin; Lee, Yi-Chao; Tsai, Ting-Fen; Takahashi, Hiroshi; Wagner, Michael et al.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4(+)CD44(hi) Cells

Immunity
2008 | Journal article
WOSUID:

WOS:000261036000013

Contributors: Hill, Jonathan A.; Hall, Jason A.; Sun, Cheng-Ming; Cai, Qi; Ghyselinck, Norbert; Chambon, Pierre; Belkaid, Yasmine; Mathis, Diane; Benoist, Christophe
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID

Retinoid X receptor beta (RXRB) expression in Sertoli cells controls cholesterol homeostasis and spermiation

Reproduction
2008 | Journal article
WOSUID:

WOS:000261000200010

Contributors: Vernet, Nadege; Dennefeld, Christine; Klopfenstein, Muriel; Ruiz, Alberto; Bok, Dean; Ghyselinck, Norbert B.; Mark, Manuel
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID
grade
Preferred source (of 2)‎

STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation

Journal of Cell Science
2008 | Journal article
WOSUID:

WOS:000259288200014

Contributors: Mark, Manuel; Jacobs, Hugues; Oulad-Abdelghani, Mustapha; Dennefeld, Christine; Feret, Betty; Vernet, Nadege; Codreanu, Carmen-Alina; Chambon, Pierre; Ghyselinck, Norbert B.
Source: Self-asserted source
Norbert GHYSELINCK via ResearcherID
Items per page:
Page 1 of 4