Personal information

Verified email addresses

Genetic diseases of nerve system, Regulation of neuronal development, Molecular genetics of brain function, ncRNA omics and regulatory network, Molecular network

Activities

Employment (4)

Southern Medical University: Guangzhou, Guangdong, CN

2015-01-01 to present | Professor of Genetics
Employment
Source: Self-asserted source
Xinping Yang

University of Illinois at Chicago: Chicago, IL, US

2014-07-01 to 2014-12-31 | Research Assistant Professor (Department of Psychiatry)
Employment
Source: Self-asserted source
Xinping Yang

Dana Farber Cancer Institute, Harvard Medical School: Boston, MA, US

2005-08-01 to 2013-12-31 | Research Fellow (Center for Cancer Systems Biology)
Employment
Source: Self-asserted source
Xinping Yang

Dana Farber Cancer Institute, Harvard Medical School: Boston, MA, US

2000-03-01 to 2005-07-31 | Research Associate (Medical Oncology)
Employment
Source: Self-asserted source
Xinping Yang

Education and qualifications (3)

Central South University Xiangya School of Medicine: Changsha, Hunan, CN

1995-09-01 to 1998-07-07 | Ph.D.
Education
Source: Self-asserted source
Xinping Yang

Institute of Genetics and Developmental Biology Chinese Academy of Sciences: Beijing, Beijing, CN

1991-09-01 to 1994-07-07 | M.S.
Education
Source: Self-asserted source
Xinping Yang

Hunan Normal University: Changsha, Hunan, CN

1979-09-01 to 1983-07-07 | B.S.
Education
Source: Self-asserted source
Xinping Yang

Professional activities (3)

Genetics Society of China -Branch for Behavioral Genetics: Changsha, Hunan, CN

2020-09-01 to present | Committee Member of Branch Behavioral Genetics
Service
Source: Self-asserted source
Xinping Yang

Medical Association of Guangdong Province, Genetics Branch: Guangzhou, CN

2019-05 to present | Committee Member of Genetics Branch
Membership
Source: Self-asserted source
Xinping Yang

Association for Genetics of Guangdong Province: Guangzhou, CN

2018-07 to present | Director
Membership
Source: Self-asserted source
Xinping Yang

Funding (6)

High-throughput construction of protein interaction network for schizophrenia to search for the molecular mechanism linking immune activation to this disorder

2021-01 to 2023-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER: 82071503
Source: Self-asserted source
Xinping Yang

Systematic mapping lncRNA-protein interaction network of human fetal brain

2018-01 to 2021-12 | Grant
National Natural Science Foundation of China (Beijing, Grant No. 31771434, CN)
GRANT_NUMBER: 31771434
Source: Self-asserted source
Xinping Yang

Molecular signatures for clinical subtypes towards personal medicine of schizophrenia

2017-07 to 2020-06 | Grant
Guangdong Science and Technology Department (Guangzhou, CN)
GRANT_NUMBER: 2017B020227010
Source: Self-asserted source
Xinping Yang

Molecular subtypes of autism and their potential application in clinical diagnosis

2017-05 to 2020-04 | Grant
Science and Technology Bureau of Guanzhou City (Guangzhou, CN)
GRANT_NUMBER: 201704020116
Source: Self-asserted source
Xinping Yang

Systematic searching for synapse regulatory pathways underlying autism

2016-01 to 2020-06 | Grant
Natural Science Foundation of Guangdong Province (Guangzhou, CN)
GRANT_NUMBER: 2016A030308020
Source: Self-asserted source
Xinping Yang

Study on key nodes of the synaptic function related modules in an autism protein-protein interaction network

2016-01 to 2019-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER: 81571097
Source: Self-asserted source
Xinping Yang

Works (33)

Maternal immune activation upregulates the AU020206-IRFs-STAT1 axis in modulating cytokine production in the brain

Theranostics
2024 | Journal article
Part of ISSN: 1838-7640
Contributors: Jing Yang; Wenjun Yu; Runmiao Zhu; Shuangyan Li; Yue Gao; Jinfa Chen; Bin Zhang; Wanshan Wang; Xinping Yang
Source: Self-asserted source
Xinping Yang

Hierarchical lncRNA regulatory network in early-onset severe preeclampsia

BMC Biology
2024-07-29 | Journal article | Author
Part of ISSN: 1741-7007
Contributors: Haihua Liu; Zhijian Wang; Yanjun Li; Qian Chen; Sijia Jiang; Yue Gao; Jing Wang; Yali Chi; Jie Liu; Xiaoli Wu et al.
Source: Self-asserted source
Xinping Yang

Systematic discovery of virus-perturbed molecular pathways linking to schizophrenia

The Innovation Medicine
2024-04-08 | Journal article
Part of ISSN: 2959-8745
Contributors: Guanmei Liang; Wenjuan Yi; Yanjun Li; Yue Gao; Lang Huang; Yanmei Lin; Chunlin Chen; Xinping Yang
Source: Self-asserted source
Xinping Yang

Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1-/- mice

iScience
2023-07 | Journal article | Author
Part of ISSN: 2589-0042
Contributors: Jing Wang; Yue Gao; Liuyan Xiao; Yanmei Lin; Lang Huang; Jinfa Chen; Guanmei Liang; Weiming Li; Wenjuan Yi; Jianpei Lao et al.
Source: Self-asserted source
Xinping Yang

Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia.

Journal of translational medicine
2023-07-24 | Journal article | Author
Contributors: Chen Q; He J; Liu H; Huang Q; Wang S; Yin A; Chen S; Shen X; Xiao Y; Hu H et al.
Source: Self-asserted source
Xinping Yang

Distinct placental molecular processes associated with early-onset and late-onset preeclampsia

Theranostics
2021 | Journal article
Part of ISSN: 1838-7640
Source: Self-asserted source
Xinping Yang

Upregulated NMDAR-enhanced GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice

Theranostics
2021 | Journal article
Part of ISSN: 1838-7640
Source: Self-asserted source
Xinping Yang

Systematic discovery of signaling pathways linking immune activation to schizophrenia

iScience
2021-11 | Journal article
Contributors: Yue Gao; Yanjun Li; ShuangYan Li; Xiaozhen Liang; Zhonglu Ren; Xiaoxue Yang; Bin Zhang; Yanhui Hu; Xinping Yang
Source: check_circle
Crossref

Preeclampsia-Associated lncRNA INHBA-AS1 Regulates the Proliferation, Invasion, and Migration of Placental Trophoblast Cells

Molecular Therapy - Nucleic Acids
2020-12 | Journal article
Part of ISSN: 2162-2531
Source: Self-asserted source
Xinping Yang

Association of lncRNA SH3PXD2A-AS1 with preeclampsia and its function in invasion and migration of placental trophoblast cells

Cell Death & Disease
2020-07 | Journal article
Part of ISSN: 2041-4889
Source: Self-asserted source
Xinping Yang

Landscape of Dysregulated Placental RNA Editing Associated With Preeclampsia.

Hypertension (Dallas, Tex. : 1979)
2020-04-20 | Journal article
Source: Self-asserted source
Xinping Yang

A reference map of the human binary protein interactome.

Nature
2020-04-08 | Journal article
Source: Self-asserted source
Xinping Yang

Whole-Genome Promoter Profiling of Plasma DNA Exhibits Diagnostic Value for Placenta-Origin Pregnancy Complications.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
2020-02-18 | Journal article
Source: Self-asserted source
Xinping Yang

Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy.

Molecular Autism
2020-02-07 | Journal article
Source: Self-asserted source
Xinping Yang

An inter-species protein-protein interaction network across vast evolutionary distance.

Molecular systems biology
2016-04-22 | Journal article
Source: Self-asserted source
Xinping Yang

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Cell
2016-02-01 | Journal article
Source: Self-asserted source
Xinping Yang

Widespread macromolecular interaction perturbations in human genetic disorders.

Cell
2015-04-01 | Journal article
Source: Self-asserted source
Xinping Yang

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases.

Neuron
2015-02-01 | Journal article
Source: Self-asserted source
Xinping Yang

A proteome-scale map of the human interactome network.

Cell
2014-11-01 | Journal article
Source: Self-asserted source
Xinping Yang

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

Nature Communications
2014-04-11 | Journal article
Source: Self-asserted source
Xinping Yang

SH3 interactome conserves general function over specific form.

Molecular Systems Biology
2013-01-01 | Journal article
Source: Self-asserted source
Xinping Yang

Evidence for transcript networks composed of chimeric RNAs in human cells.

PloS One
2012-01-04 | Journal article
Source: Self-asserted source
Xinping Yang

AKT1 induces caspase-mediated cleavage of the CDK inhibitor p27Kip1 during cell cycle progression in leukemia cells transformed by FLT3-ITD.

Leukemia Research
2011-12-03 | Journal article
Source: Self-asserted source
Xinping Yang

Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.

Nature methods
2011-10-30 | Journal article
Source: Self-asserted source
Xinping Yang

A public genome-scale lentiviral expression library of human ORFs.

Nature methods
2011-06-26 | Journal article
Source: Self-asserted source
Xinping Yang

Genome-wide functional annotation and structural verification of metabolic ORFeome of Chlamydomonas reinhardtii.

BMC genomics
2011-06-15 | Journal article
Source: Self-asserted source
Xinping Yang

Next-generation sequencing to generate interactome datasets.

Nature methods
2011-04-24 | Journal article
Source: Self-asserted source
Xinping Yang

Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome.

Genome research
2009-10-02 | Journal article
Source: Self-asserted source
Xinping Yang

Metabolic network analysis integrated with transcript verification for sequenced genomes.

Nature methods
2009-07-13 | Journal article
Source: Self-asserted source
Xinping Yang
grade
Preferred source (of 2)‎

Isoform discovery by targeted cloning, 'deep-well' pooling and parallel sequencing.

Nature methods
2008-06-15 | Journal article
Source: Self-asserted source
Xinping Yang

The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.

Cancer research
2005-08-01 | Journal article
Source: Self-asserted source
Xinping Yang

Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1.

Nature genetics
2001-08-01 | Journal article
Source: Self-asserted source
Xinping Yang

A locus for brachydactyly type A-1 maps to chromosome 2q35-q36.

American journal of human genetics
2000-03-01 | Journal article
Source: Self-asserted source
Xinping Yang

Peer review (5 reviews for 4 publications/grants)

Review activity for Advanced science. (2)
Review activity for Brain, behavior, and immunity. (1)
Review activity for Communications biology. (1)
Review activity for Genes & diseases. (1)