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Simula Research Laboratory AS: Lysaker, NO

Senior Research Scientist (Computational physiology)
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Karoline Horgmo Jæger

Works (11)

Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

2022-09-07 | Preprint
Contributors: Karoline Horgmo Jæger; Ena Ivanovic; Jan P. Kucera; Aslak Tveito
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Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science
2022-08-12 | Journal article
Contributors: Verena Charwat; Bérénice Charrez; Brian A. Siemons; Henrik Finsberg; Karoline H. Jæger; Andrew G. Edwards; Nathaniel Huebsch; Samuel Wall; Evan Miller; Aslak Tveito et al.
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Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips

Nature Biomedical Engineering
2022-04-27 | Journal article
Contributors: Nathaniel Huebsch; Berenice Charrez; Gabriel Neiman; Brian Siemons; Steven C. Boggess; Samuel Wall; Verena Charwat; Karoline H. Jæger; David Cleres; Åshild Telle et al.
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A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes

PLOS Computational Biology
2021-08-12 | Journal article
Contributors: Karoline Horgmo Jæger; Daniel A. Beard; Andrew G. Edwards; Wayne R. Giles; Aslak Tveito
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Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

PLOS Computational Biology
2021-02-16 | Journal article
Contributors: Karoline Horgmo Jæger; Daniel A. Beard; Samuel Wall; Aslak Tveito
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Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

2020-06-24 | Preprint
Contributors: Karoline Horgmo Jæger; Samuel Wall; Aslak Tveito
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Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems

2020-05-31 | Preprint
Contributors: Karoline Horgmo Jæger; Verena Charwat; Sam Wall; Kevin E. Healy; Aslak Tveito
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Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems

2019-10-01 | Other
Contributors: Karoline Horgmo Jæger; Verena Charwat; Bérénice Charrez; Henrik Finsberg; Mary M. Maleckar; Samuel Wall; Kevin E. Healy; Aslak Tveito
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Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?

Chaos: An Interdisciplinary Journal of Nonlinear Science
2019-07 | Journal article
Contributors: Karoline Horgmo Jæger; Samuel Wall; Aslak Tveito
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Properties of cardiac conduction in a cell-based computational model

PLOS Computational Biology
2019-05-31 | Journal article
Contributors: Karoline Horgmo Jæger; Zhilin Qu; Andrew G. Edwards; Andrew McCulloch; Aslak Tveito
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How does the presence of neural probes affect extracellular potentials?

Journal of Neural Engineering
2019-04-01 | Journal article
Contributors: Alessio Paolo Buccino; Miroslav Kuchta; Karoline Horgmo Jæger; Torbjørn Vefferstad Ness; Pierre Berthet; Kent-Andre Mardal; Gert Cauwenberghs; Aslak Tveito
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