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Genetics, Bone Biology, Complex traits
United States

Activities

Employment (4)

UC Health University of Colorado Hospital: Aurora, CO, US

2019-08-01 to present | Professor (Department of Orthopedics)
Employment
Source: Self-asserted source
Cheryl Ackert-Bicknell

The University of Rochester: Rochester, New York, US

2014-08-01 to 2019-07-31 | Associate Professor (Center for Musculoskeletal Research)
Employment
Source: Self-asserted source
Cheryl Ackert-Bicknell

Jackson Laboratory: Bar Harbor, ME, US

2010-09 to 2014-07-24 | Research Scientist
Employment
Source: Self-asserted source
Cheryl Ackert-Bicknell

Jackson Laboratory: Bar Harbor, ME, US

2008-01-03 to 2010-09 | Post Doctoral Fellow
Employment
Source: Self-asserted source
Cheryl Ackert-Bicknell

Education and qualifications (3)

University of Maine: Orono, ME, US

2005-09 to 2007-12 | PhD
Education
Source: Self-asserted source
Cheryl Ackert-Bicknell

University of Western Ontario Department : London, ON, CA

1997 to 2000 | MSc
Education
Source: Self-asserted source
Cheryl Ackert-Bicknell

University of Guelph: Guelph, ON, CA

1993 to 1997 | HonBSc
Education
Source: Self-asserted source
Cheryl Ackert-Bicknell

Professional activities (2)

American Society for Bone and Mineral Research: Washington, DC, US

Membership
Source: Self-asserted source
Cheryl Ackert-Bicknell

Orthopedics Research Socitey: Rosemont, IL, US

2014-01-01 to present
Membership
Source: Self-asserted source
Cheryl Ackert-Bicknell

Funding (9)

Systems Genetics of Osteoblast Activity

2015-09-21 to 2020-06-30 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R01AR064790
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Systems Genetics of Osteoblast Activity

2013-09-27 to 2015-09-20 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R56AR064790
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Skeletal Phenotyping of KOMP Mice

2013-08-01 to 2019-05-31 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R01AR063702
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Genetics of Osteoblast Differentiation

2011-03-15 to 2014-02-28 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R21AR060981
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Co-localizing Quantitative Trait Loci for Bone Mineral Density and HDL in Mice

2010-09-20 to 2016-05-31 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, US)
GRANT_NUMBER: R01AR060234
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Examination of Co-inheritance of Bone Mineral Density, IGF-1 and Lifespan

2009-03-09 to 2010-09-16 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: F32AG034019
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

The effects of allelic variation in Pparg on skeletal metabolism

2007-07-07 to 2008-01-04 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: F31AG030910
Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Development of the female germ line in Cx43 null m utant mice.

1997-09-01 to 1999-04-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
GRANT_NUMBER:

b22498442352c7907484a39b63e3a5a3

Source: Self-asserted source
Cheryl Ackert-Bicknell via DimensionsWizard

Skeletal Phenotyping of KOMP mice

Grant
NIH (Bethesda, US)
Source: Self-asserted source
Cheryl Ackert-Bicknell

Works (50 of 87)

Items per page:
Page 1 of 2

Early life lipid overload in Native American Myopathy is phenocopied by stac3 knockout in zebrafish

Gene
2025-02 | Journal article
Contributors: Rajashekar Donaka; Houfeng Zheng; Cheryl L Ackert-Bicknell; David Karasik
Source: check_circle
Crossref

GWAS-Informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density

2024-03-20 | Preprint
Contributors: Mitchell Conery; James A. Pippin; Yadav Wagley; Khanh Trang; Matthew C. Pahl; David A. Villani; Lacey J. Favazzo; Cheryl L. Ackert-Bicknell; Michael J. Zuscik; Eugene Katsevich et al.
Source: check_circle
Crossref

Zebrafish as a Model for Osteoporosis: Functional Validations of Genome-Wide Association Studies

Current Osteoporosis Reports
2023-12 | Journal article
Contributors: Inbar Ben-Zvi; David Karasik; Cheryl L. Ackert-Bicknell
Source: check_circle
Crossref

Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis.

Communications biology
2023-07-04 | Journal article
Contributors: Carolina Medina-Gomez; Benjamin Mullin; Chesi A; Vid Prijatelj; John P. Kemp; Shochat-Carvalho C; Trajanoska K; Wang C; Joro R; Tavia Evans et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell

Functional screens refine height GWAS loci

Cell Genomics
2023-05 | Journal article
Contributors: Cheryl L. Ackert-Bicknell
Source: check_circle
Crossref

Proceedings of the Post-Genome Analysis for Musculoskeletal Biology Workshop

Current Osteoporosis Reports
2023-04 | Journal article
Contributors: Cheryl Ackert-Bicknell; David Karasik
Source: check_circle
Crossref

Genetics of Intervertebral Disc Degeneration

Current Osteoporosis Reports
2023-02 | Journal article
Contributors: David C. Ou-Yang; Christopher J. Kleck; Cheryl L. Ackert-Bicknell
Source: check_circle
Crossref

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.

BMC biology
2023-02-03 | Journal article
Contributors: Chee JM; Lanoue L; Clary D; Higgins K; Bower L; Flenniken A; Guo R; Adams DJ; Bosch F; Braun RE et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell

Whole-genome RNA sequencing identifies distinct transcriptomic profiles in impingement cartilage between patients with femoroacetabular impingement and hip osteoarthritis.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2022-12-04 | Journal article
Contributors: Benjamin Kuhns; Reuter JM; Hansen VL; Soles GL; Jonason JH; Ackert-Bicknell CL; Wu CL; Giordano BD
Source: Self-asserted source
Cheryl Ackert-Bicknell

Detecting isoform-level allelic imbalance accounting for inferential uncertainty

2022-08-13 | Preprint
Contributors: Euphy Wu; Noor P. Singh; Kwangbom Choi; Mohsen Zakeri; Matthew Vincent; Gary A. Churchill; Cheryl L. Ackert-Bicknell; Rob Patro; Michael I. Love
Source: check_circle
Crossref

HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation.

Blood
2022-05-01 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

Understanding the Transcriptomic Landscape to Drive New Innovations in Musculoskeletal Regenerative Medicine.

Current osteoporosis reports
2022-02-14 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

A computational approach for identification of core modules from a co-expression network and GWAS data.

STAR protocols
2021-08-21 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell
grade
Preferred source (of 2)‎

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.

Nature communications
2021-01-28 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

Isolation and Culture of Neonatal Mouse Calvarial Osteoblasts.

Methods in molecular biology (Clifton, N.J.)
2021-01-01 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data.

Cell reports
2020-09-01 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

A Bioinformatic Approach to Utilize a Patient's Antibody-Secreting Cells against Staphylococcus aureus to Detect Challenging Musculoskeletal Infections.

ImmunoHorizons
2020-06-22 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell
grade
Preferred source (of 3)‎

Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass.

PLoS genetics
2020-06-04 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell
grade
Preferred source (of 2)‎

Genetic Dissection of Femoral and Tibial Microarchitecture.

JBMR Plus
2019-11-11 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

Genetic Analysis of Osteoblast Activity Identifies Zbtb40 as a Regulator of Osteoblast Activity and Bone Mass

2019-11-01 | Preprint
Contributors: Madison L. Doolittle; Gina M Calabrese; Larry D. Mesner; Dana A. Godfrey; Robert D. Maynard; Cheryl L. Ackert-Bicknell; Charles R. Farber
Source: check_circle
Crossref

Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass.

PLoS genetics
2019-05 | Journal article
Contributors: Mesner LD; Calabrese GM; Al-Barghouthi B; Gatti DM; Sundberg JP; Churchill GA; Godfrey DA; Ackert-Bicknell CL; Farber CR
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Mouse Models and Online Resources for Functional Analysis of Osteoporosis Genome-Wide Association Studies.

Frontiers in Endocrinology
2019-05-07 | Journal article
Source: Self-asserted source
Cheryl Ackert-Bicknell

Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2019-03 | Journal article
Contributors: Hsu YH; Estrada K; Evangelou E; Ackert-Bicknell C; Akesson K; Beck T; Brown SJ; Capellini T; Carbone L; Cauley J et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Genetic dissection of femoral and tibial microarchitecture

2019-01 | Other
OTHER-ID:

PPR66593

Contributors: Lu L; Huang J; Xu F; Xiao Z; Wang J; Zhang B; David NV; Arends D; Gu W; Ackert-Bicknell C et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

An atlas of genetic influences on osteoporosis in humans and mice.

Nature genetics
2018-12 | Journal article
Contributors: Morris JA; Kemp JP; Youlten SE; Laurent L; Logan JG; Chai RC; Vulpescu NA; Forgetta V; Kleinman A; Mohanty ST et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central
grade
Preferred source (of 3)‎

Mouse Genome-Wide Association and Systems Genetics Identifies Lhfp as a Regulator of Bone Mass

2018-10 | Other
OTHER-ID:

PPR60158

Contributors: Mesner LD; Calabrese GM; Al-Barghouthi B; Gatti DM; Sundberg JP; Churchill GA; Godfrey D; Ackert-Bicknell C; Farber CR
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.

BMJ (Clinical research ed.)
2018-08 | Journal article
Contributors: Trajanoska K; Morris JA; Oei L; Zheng HF; Evans DM; Kiel DP; Ohlsson C; Richards JB; Rivadeneira F; GEFOS/GENOMOS consortium and the 23andMe research team
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

An Atlas of Human and Murine Genetic Influences on Osteoporosis

2018-06 | Other
OTHER-ID:

PPR9953

Contributors: Morris JA; Kemp JP; Youlten SE; Laurent L; Logan JG; Chai R; Vulpescu NA; Forgetta V; Kleinman A; Mohanty S et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Characterization of expression and alternative splicing of the gene cadherin-like and PC esterase domain containing 1 (Cped1).

Gene
2018-06 | Journal article
Contributors: Maynard RD; Godfrey DA; Medina-Gomez C; Ackert-Bicknell CL
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by μCT and Histomorphometry.

Current osteoporosis reports
2018-04 | Journal article
Contributors: Rowe DW; Adams DJ; Hong SH; Zhang C; Shin DG; Renata Rydzik C; Chen L; Wu Z; Garland G; Godfrey DA et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Targeting the gut microbiome to treat the osteoarthritis of obesity.

JCI insight
2018-04 | Journal article
Contributors: Schott EM; Farnsworth CW; Grier A; Lillis JA; Soniwala S; Dadourian GH; Bell RD; Doolittle ML; Villani DA; Awad H et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

American journal of human genetics
2018-01 | Journal article
Contributors: Medina-Gomez C; Kemp JP; Trajanoska K; Luan J; Chesi A; Ahluwalia TS; Mook-Kanamori DO; Ham A; Hartwig FP; Evans DS et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

Nature genetics
2017-09 | Journal article
Contributors: Kemp JP; Morris JA; Medina-Gomez C; Forgetta V; Warrington NM; Youlten SE; Zheng J; Gregson CL; Grundberg E; Trajanoska K et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.

Nature communications
2017-07 | Journal article
Contributors: Medina-Gomez C; Kemp JP; Dimou NL; Kreiner E; Chesi A; Zemel BS; Bønnelykke K; Boer CG; Ahluwalia TS; Bisgaard H et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

A mutagenesis-derived Lrp5 mouse mutant with abnormal retinal vasculature and low bone mineral density.

Molecular vision
2017-03 | Journal article
Contributors: Charette JR; Earp SE; Bell BA; Ackert-Bicknell CL; Godfrey DA; Rao S; Anand-Apte B; Nishina PM; Peachey NS
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

High-Throughput, Multi-Image Cryohistology of Mineralized Tissues.

Journal of visualized experiments : JoVE
2016-09 | Journal article
Contributors: Dyment NA; Jiang X; Chen L; Hong SH; Adams DJ; Ackert-Bicknell C; Shin DG; Rowe DW
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2016-09 | Journal article
Contributors: Nielson CM; Liu CT; Smith AV; Ackert-Bicknell CL; Reppe S; Jakobsdottir J; Wassel C; Register TC; Oei L; Alonso N et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.

Nature genetics
2016-07 | Journal article
Contributors: Parker CC; Gopalakrishnan S; Carbonetto P; Gonzales NM; Leung E; Park YJ; Aryee E; Davis J; Blizard DA; Ackert-Bicknell CL et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Genetics of aging bone.

Mammalian genome : official journal of the International Mammalian Genome Society
2016-06 | Journal article
Contributors: Adams DJ; Rowe DW; Ackert-Bicknell CL
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

How do bisphosphonates affect fracture healing?

Injury
2016-01 | Journal article
Contributors: Kates SL; Ackert-Bicknell CL
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Passenger Gene Mutations: Unwanted Guests in Genetically Modified Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2016-01 | Journal article
Contributors: Ackert-Bicknell CL; Rosen CJ
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Genetic determinants of fibro-osseous lesions in aged inbred mice.

Experimental and molecular pathology
2015-11 | Journal article
Contributors: Berndt A; Ackert-Bicknell C; Silva KA; Kennedy VE; Sundberg BA; Cates JM; Schofield PN; Sundberg JP
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination.

PLoS genetics
2015-11 | Journal article
Contributors: Pallares LF; Carbonetto P; Gopalakrishnan S; Parker CC; Ackert-Bicknell CL; Palmer AA; Tautz D
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Nature
2015-09 | Journal article
Contributors: Zheng HF; Forgetta V; Hsu YH; Estrada K; Rosello-Diez A; Leo PJ; Dahia CL; Park-Min KH; Tobias JH; Kooperberg C et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Genetic regulation of bone strength: a review of animal model studies.

BoneKEy reports
2015-07 | Journal article
Contributors: Adams DJ; Ackert-Bicknell CL
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Aging Research Using Mouse Models.

Current protocols in mouse biology
2015-06 | Journal article
Contributors: Ackert-Bicknell CL; Anderson LC; Sheehan S; Hill WG; Chang B; Churchill GA; Chesler EJ; Korstanje R; Peters LL
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Fixation stability dictates the differentiation pathway of periosteal progenitor cells in fracture repair.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2015-05 | Journal article
Contributors: Hagiwara Y; Dyment NA; Jiang X; Jiang Ping H; Ackert-Bicknell C; Adams DJ; Rowe DW
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.

The journals of gerontology. Series A, Biological sciences and medical sciences
2014-12 | Journal article
Contributors: Bogue MA; Peters LL; Paigen B; Korstanje R; Yuan R; Ackert-Bicknell C; Grubb SC; Churchill GA; Chesler EJ
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.

PLoS genetics
2014-06 | Journal article
Contributors: Kemp JP; Medina-Gomez C; Estrada K; St Pourcain B; Heppe DH; Warrington NM; Oei L; Ring SM; Kruithof CJ; Timpson NJ et al.
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central

Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait.

American journal of physiology. Renal physiology
2014-04 | Journal article
Contributors: Yu W; Ackert-Bicknell C; Larigakis JD; MacIver B; Steers WD; Churchill GA; Hill WG; Zeidel ML
Source: Self-asserted source
Cheryl Ackert-Bicknell via Europe PubMed Central
Items per page:
Page 1 of 2

Peer review (16 reviews for 7 publications/grants)

Review activity for Bone reports. (2)
Review activity for Bone. (5)
Review activity for eLife (1)
Review activity for Endocrine reviews. (2)
Review activity for Journal of the Endocrine Society. (1)
Review activity for Osteoporosis international. (4)
Review activity for PloS one. (1)