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Scopus Author ID: 56595864500

Keywords

skeletal development, Cartilage, Bone, miRNA, Epigenetics

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Employment (1)

Massachusetts General Hospital: Boston, MA, US

1997-09 to present | PI (Endocrine)
Employment
Source: Self-asserted source
Tatsuya Kobayashi

Funding (3)

Role of miR-17-92 miRNAs in skeletal development and bone homeostasis

2010-04-01 to 2021-02-28 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (n/a, US)
URL: https://grants.uberresearch.com/100000069/R01AR056645/Role-of-miR-17-92-miRNAs-in-skeletal-development-and-bone-homeostasis
GRANT_NUMBER: grant.R01AR056645
Source: Self-asserted source
Tatsuya Kobayashi via DimensionsWizard

Role of let-7 microRNAs in skeletal development

2009-04-01 to 2012-03-31 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (n/a, US)
URL: https://grants.uberresearch.com/100000069/R21AR057134/Role-of-let-7-microRNAs-in-skeletal-development
GRANT_NUMBER: grant.R21AR057134
Source: Self-asserted source
Tatsuya Kobayashi via DimensionsWizard

Small RNAs in skeletogenesis

2007-04-01 to 2009-09-30 | Grant
National Institute of Arthritis and Musculoskeletal and Skin Diseases (n/a, US)
URL: https://grants.uberresearch.com/100000069/R21AR054500/Small-RNAs-in-skeletogenesis
GRANT_NUMBER: grant.R21AR054500
Source: Self-asserted source
Tatsuya Kobayashi via DimensionsWizard

Works (50 of 62)

Items per page:
Page 1 of 2

Gain-of-function mutation of microRNA-140 in human skeletal dysplasia

Nature Medicine
2019-04 | Journal article
DOI: 10.1038/s41591-019-0353-2
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Tatsuya Kobayashi

PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy

JCI Insight
2019-03-07 | Journal article
DOI: 10.1172/jci.insight.97903
Part of ISSN: 2379-3708
Source: Self-asserted source
Tatsuya Kobayashi

Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

Neuron
2018-12 | Journal article
DOI: 10.1016/j.neuron.2018.10.008
Part of ISSN: 0896-6273
Source: Self-asserted source
Tatsuya Kobayashi

Lin28a overexpression reveals the role of Erk signaling in articular cartilage development

Development
2018-08-01 | Journal article
DOI: 10.1242/dev.162594
Contributors: Tatsuya Kobayashi; Anastasia Kozlova
Source: check_circle
Crossref

Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

Nature Genetics
2018-05 | Journal article
DOI: 10.1038/s41588-018-0104-1
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models

Nature Communications
2018-04-10 | Journal article
DOI: 10.1038/s41467-018-03788-7
Part of ISSN: 2041-1723
Contributors: Fatemeh Mirzamohammadi; Anastasia Kozlova; Garyfallia Papaioannou; Elena Paltrinieri; Ugur M. Ayturk; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Ras signaling regulates osteoprogenitor cell proliferation and bone formation

Cell Death and Disease
2016-10 | Journal article
DOI: 10.1038/cddis.2016.314
Part of ISSN: 2041-4889
Contributors: Garyfallia Papaioannou; Fatemeh Mirzamohammadi; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone–related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor

The FASEB Journal
2016-08 | Journal article
DOI: 10.1096/fj.201600261r
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Source: Self-asserted source
Tatsuya Kobayashi

Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling

Nature Communications
2016-06 | Journal article
DOI: 10.1038/ncomms12047
Part of ISSN: 2041-1723
Contributors: Fatemeh Mirzamohammadi; Garyfallia Papaioannou; Jennifer B. Inloes; Erinn B. Rankin; Huafeng Xie; Ernestina Schipani; Stuart H. Orkin; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis

The FASEB Journal
2016-01 | Journal article
DOI: 10.1096/fj.15-278184
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Source: Self-asserted source
Tatsuya Kobayashi

miRNAs in Bone Formation and Homeostasis

MicroRNA in Regenerative Medicine
2015 | Other
DOI: 10.1016/b978-0-12-405544-5.00014-9
Part of ISBN: 9780124055445
Contributors: Garyfallia Papaioannou; Thomas Lisse; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

miRNAs in Bone Development

Current Genomics
2015-09-07 | Journal article
DOI: 10.2174/1389202916666150817202425
Part of ISSN: 1389-2029
Contributors: Garyfallia Papaioannou
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis

Endocrinology
2015-08 | Journal article
DOI: 10.1210/en.2014-1835
Part of ISSN: 0013-7227
Part of ISSN: 1945-7170
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage

Osteoarthritis and Cartilage
2015-07 | Journal article
DOI: 10.1016/j.joca.2015.02.015
Contributors: T. Kobayashi; G. Papaioannou; F. Mirzamohammadi; E. Kozhemyakina; M. Zhang; R. Blelloch; M.W. Chong
Source: check_circle
Crossref

PCSK5 mutation in a patient with the VACTERL association

BMC Research Notes
2015-06-09 | Journal article
DOI: 10.1186/s13104-015-1166-0
Part of ISSN: 1756-0500
Contributors: Yukio Nakamura; Shingo Kikugawa; Shoji Seki; Masahiko Takahata; Norimasa Iwasaki; Hidetomi Terai; Mitsuhiro Matsubara; Fumio Fujioka; Hidehito Inagaki; Tatsuya Kobayashi et al.
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway

Journal of Bone and Mineral Research
2015-05 | Journal article
DOI: 10.1002/jbmr.2438
Part of ISSN: 0884-0431
Contributors: Garyfallia Papaioannou; Fatemeh Mirzamohammadi; Thomas S Lisse; Shigeki Nishimori; Marc N Wein; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Overview of Skeletal Development

Methods in Molecular Biology
2014 | Book chapter
DOI: 10.1007/978-1-62703-989-5_1
Part of ISBN: 9781627039888
Part of ISBN: 9781627039895
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

MicroRNAs involved in bone formation

Cellular and Molecular Life Sciences
2014-08-10 | Journal article
DOI: 10.1007/s00018-014-1700-6
Part of ISSN: 1420-682X
Contributors: Garyfallia Papaioannou; Fatemeh Mirzamohammadi; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

microRNAs in Cartilage Development, Homeostasis, and Disease

Current Osteoporosis Reports
2014-08-05 | Journal article
DOI: 10.1007/s11914-014-0229-9
Part of ISSN: 1544-1873
Contributors: Fatemeh Mirzamohammadi; Garyfallia Papaioannou; Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia

Cancer Science
2014-05 | Journal article
DOI: 10.1111/cas.12391
Part of ISSN: 1347-9032
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes

Nature Communications
2014-05 | Journal article
DOI: 10.1038/ncomms4673
Part of ISSN: 2041-1723
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

let-7 and miR-140 microRNAs coordinately regulate skeletal development

Proceedings of the National Academy of Sciences
2013-08 | Journal article
DOI: 10.1073/pnas.1302797110
Part of ISSN: 0027-8424
Contributors: G. Papaioannou; J. B. Inloes; Y. Nakamura; E. Paltrinieri; T. Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

Cell Stem Cell
2012-03 | Journal article
DOI: 10.1016/j.stem.2012.02.003
Part of ISSN: 1934-5909
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Chondrocytes and cartilage biology: Meeting report from the 33rd annual meeting of the American Society for Bone and Mineral Research

IBMS BoneKEy
2011-11 | Journal article
DOI: 10.1138/20110541
Part of ISSN: 1940-8692
Contributors: Tatsuya Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Sox9 Is Upstream of MicroRNA-140 in Cartilage

Applied Biochemistry and Biotechnology
2011-11-04 | Journal article
DOI: 10.1007/s12010-011-9404-y
Part of ISSN: 0273-2289
Contributors: Yukio Nakamura; Xinjun He; Hiroyuki Kato; Shigeyuki Wakitani; Tatsuya Kobayashi; Sumiko Watanabe; Atsumi Iida; Hideaki Tahara; Matthew L. Warman; Ramida Watanapokasin et al.
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Chondrocyte-Specific MicroRNA-140 Regulates Endochondral Bone Development and Targets Dnpep To Modulate Bone Morphogenetic Protein Signaling

Molecular and Cellular Biology
2011-05 | Journal article
DOI: 10.1128/mcb.05178-11
Part of ISSN: 0270-7306
Contributors: Y. Nakamura; J. B. Inloes; T. Katagiri; T. Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses

Journal of Endocrinology
2011-04 | Journal article
DOI: 10.1530/joe-10-0308
Part of ISSN: 0022-0795
Part of ISSN: 1479-6805
Source: Self-asserted source
Tatsuya Kobayashi

Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life

Proceedings of the National Academy of Sciences
2011-01-04 | Journal article
DOI: 10.1073/pnas.1005011108
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

Developmental Cell
2010-08 | Journal article
DOI: 10.1016/j.devcel.2010.07.010
Part of ISSN: 1534-5807
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Disruption of PTH Receptor 1 in T Cells Protects against PTH-Induced Bone Loss

PLoS ONE
2010-08-20 | Journal article
DOI: 10.1371/journal.pone.0012290
Part of ISSN: 1932-6203
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

Nature
2010-03 | Journal article
DOI: 10.1038/nature08851
Part of ISSN: 0028-0836
Contributors: Marc H. G. P. Raaijmakers; Siddhartha Mukherjee; Shangqin Guo; Siyi Zhang; Tatsuya Kobayashi; Jesse A. Schoonmaker; Benjamin L. Ebert; Fatima Al-Shahrour; Robert P. Hasserjian; Edward O. Scadden et al.
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts

Journal of Bone and Mineral Research
2009 | Journal article
DOI: 10.1359/jbmr.090806
Part of ISSN: 0884-0431
Contributors: Nobuhiro Kamiya; Tatsuya Kobayashi; Yoshiyuki Mochida; Paul B Yu; Mitsuo Yamauchi; Henry M Kronenberg; Yuji Mishina
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass*

Journal of Bone and Mineral Research
2008 | Journal article
DOI: 10.1359/jbmr.080809
Part of ISSN: 0884-0431
Contributors: Nobuhiro Kamiya; Ling Ye; Tatsuya Kobayashi; Donald J Lucas; Yoshiyuki Mochida; Mitsuo Yamauchi; Henry M Kronenberg; Jian Q Feng; Yuji Mishina
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Nature Medicine
2008-02 | Journal article
DOI: 10.1038/nm1716
Part of ISSN: 1078-8956
Contributors: Matthew J Hilton; Xiaolin Tu; Ximei Wu; Shuting Bai; Haibo Zhao; Tatsuya Kobayashi; Henry M Kronenberg; Steven L Teitelbaum; F Patrick Ross; Raphael Kopan et al.
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

Proceedings of the National Academy of Sciences
2008-01 | Journal article
DOI: 10.1073/pnas.0707900105
Part of ISSN: 0027-8424
Contributors: T. Kobayashi; J. Lu; B. S. Cobb; S. J. Rodda; A. P. McMahon; E. Schipani; M. Merkenschlager; H. M. Kronenberg
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34

Journal of Clinical Investigation
2005-08 | Journal article
DOI: 10.1172/jci24918
Part of ISSN: 0021-9738
Contributors: D. Miao
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP

Journal of Clinical Investigation
2005-07-01 | Journal article
DOI: 10.1172/jci24397
Part of ISSN: 0021-9738
Contributors: T. Kobayashi
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search

Reduced expression of the PTH/PTHrP receptor during development of the mammary gland influences the function of the nipple during lactation.

Developmental dynamics : an official publication of the American Association of Anatomists
2005-07-01 | Journal article
DOI: 10.1002/dvdy.20406
PMID: 15880431
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Minireview: transcriptional regulation in development of bone.

Endocrinology
2004-12-16 | Journal article
DOI: 10.1210/en.2004-1343
PMID: 15604211
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2004-12-06 | Journal article
DOI: 10.1359/jbmr.041210
PMID: 15765186
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction.

Journal of cellular physiology
2004-10-01 | Journal article
DOI: 10.1002/jcp.20041
PMID: 15281085
Source: Self-asserted source
Tatsuya Kobayashi

Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.

Development (Cambridge, England)
2004-05-01 | Journal article
DOI: 10.1242/dev.01138
PMID: 15128677
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro.

Endocrinology
2003-11-14 | Journal article
DOI: 10.1210/en.2003-0839
PMID: 14617570
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

In Vivo Evidence That BMP Signaling Is Necessary for Apoptosis in the Mouse Limb

Developmental Biology
2002-09 | Journal article
DOI: 10.1006/dbio.2002.0752
Part of ISSN: 0012-1606
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps.

Development (Cambridge, England)
2002-06-01 | Journal article
PMID: 12050144
Source: Self-asserted source
Tatsuya Kobayashi

Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival.

Genes & development
2001-11-01 | Journal article
DOI: 10.1101/gad.934301
PMID: 11691837
PMC: PMC312800
Source: Self-asserted source
Tatsuya Kobayashi

Association between parathyroid hormone (PTH)/PTH-related peptide receptor gene polymorphism and the extent of bone mass reduction in primary hyperparathyroidism.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
2000-09-01 | Journal article
DOI: 10.1055/s-2007-978652
PMID: 11014383
Source: Self-asserted source
Tatsuya Kobayashi

Evaluation of changes in bone density and biochemical parameters after parathyroidectomy in primary hyperparathyroidism.

Endocrine journal
2000-06-01 | Journal article
DOI: 10.1507/endocrj.47.231
PMID: 11036865
Source: Self-asserted source
Tatsuya Kobayashi
grade
Preferred source (of 2)‎

Prediction of bone mass change after parathyroidectomy in patients with primary hyperparathyroidism.

The Journal of clinical endocrinology and metabolism
2000-05-01 | Journal article
DOI: 10.1210/jcem.85.5.6604
PMID: 10843172
Source: Self-asserted source
Tatsuya Kobayashi

Parathyroid hormone gene polymorphisms in primary hyperparathyroidism

Clinical Endocrinology
1999-05 | Journal article
DOI: 10.1046/j.1365-2265.1999.00685.x
Part of ISSN: 0300-0664
Contributors: Michiko Kanzawa; Toshitsugu Sugimoto; Tatsuya Kobayashi; Akira Kobayashi; Kazuo Chihara
Source: Self-asserted source
Tatsuya Kobayashi via Crossref Metadata Search
Items per page:
Page 1 of 2

Peer review (9 reviews for 8 publications/grants)

Review activity for Bone Research. (1)
Review activity for Communications biology. (1)
Review activity for EBioMedicine. (1)
Review activity for eLife (2)
Review activity for Gene therapy. (1)
Review activity for Osteoarthritis and cartilage (1)
Review activity for PLOS genetics. (1)
Review activity for Stem cell research & therapy. (1)
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