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Works (15)

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

Science Advances
2024-09-06 | Journal article
DOI: 10.1126/sciadv.adj4632
Contributors: Vanessa Mühlgrabner; Timo Peters; Rubí M.-H. Velasco Cárdenas; Benjamin Salzer; Janett Göhring; Angelika Plach; Maria Höhrhan; Iago Doel Perez; Vasco Dos Reis Goncalves; Jesús Siller Farfán et al.
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Interrogating ligand-receptor interactions using highly sensitive cellular biosensors

Nature Communications
2023-11-28 | Journal article
DOI: 10.1038/s41467-023-43589-1
Contributors: Maximilian A. Funk; Judith Leitner; Marlene C. Gerner; Jasmin M. Hammerler; Benjamin Salzer; Manfred Lehner; Claire Battin; Simon Gumpelmair; Karin Stiasny; Katharina Grabmeier-Pfistershammer et al.
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The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif

Science Signaling
2023-10-03 | Journal article
DOI: 10.1126/scisignal.adg2610
Contributors: Katharina Aigner-Radakovics; Annika De Sousa Linhares; Benjamin Salzer; Manfred Lehner; Shiva Izadi; Alexandra Castilho; Winfried F. Pickl; Judith Leitner; Peter Steinberger
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TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

2023-03-17 | Preprint
DOI: 10.1101/2023.03.16.532775
Contributors: Timo Peters; Vanessa Mühlgrabner; Rubí M.-H. Velasco Cárdenas; René Platzer; Janett Göhring; Benjamin Salzer; Angelika Plach; Maria Höhrhan; Iago Doel Perez; Vasco Dos Reis Goncalves et al.
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Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors

Proceedings of the National Academy of Sciences
2023-01-10 | Journal article
DOI: 10.1073/pnas.2216352120
Contributors: Jake Burton; Jesús A. Siller-Farfán; Johannes Pettmann; Benjamin Salzer; Mikhail Kutuzov; P. Anton van der Merwe; Omer Dushek
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Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors

2021-10-28 | Preprint
DOI: 10.1101/2021.10.26.465853
Contributors: Jake Burton; Jesús A. Siller-Farfán; Johannes Pettmann; Benjamin Salzer; Mikhail Kutuzov; P. Anton van der Merwe; Omer Dushek
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Driving CARs with alternative navigation tools – the potential of engineered binding scaffolds

The FEBS Journal
2021-04 | Journal article
DOI: 10.1111/febs.15523
Contributors: Charlotte U. Zajc; Benjamin Salzer; Joseph M. Taft; Sai T. Reddy; Manfred Lehner; Michael W. Traxlmayr
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Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function

Nature Communications
2020-08-20 | Journal article
DOI: 10.1038/s41467-020-17970-3
Contributors: Benjamin Salzer; Christina M. Schueller; Charlotte U. Zajc; Timo Peters; Michael A. Schoeber; Boris Kovacic; Michelle C. Buri; Elisabeth Lobner; Omer Dushek; Johannes B. Huppa et al.
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Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide.

Therapeutic advances in medical oncology
2020-07-29 | Journal article
DOI: 10.1177/1758835920937891
PMID: 32774473
PMC: PMC7391428
Source: Self-asserted source
Benjamin Salzer

A conformation-specific ON-switch for controlling CAR T cells with an orally available drug

Proceedings of the National Academy of Sciences
2020-06-30 | Journal article
DOI: 10.1073/pnas.1911154117
Contributors: Charlotte U. Zajc; Markus Dobersberger; Irene Schaffner; Georg Mlynek; Dominic Pühringer; Benjamin Salzer; Kristina Djinović-Carugo; Peter Steinberger; Annika De Sousa Linhares; Nicole J. Yang et al.
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A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells in Vivo

Cancers
2020-02-29 | Journal article
DOI: 10.3390/cancers12030567
Contributors: Susana Pascoal; Benjamin Salzer; Eva Scheuringer; Andrea Wenninger-Weinzierl; Caterina Sturtzel; Wolfgang Holter; Sabine Taschner-Mandl; Manfred Lehner; Martin Distel
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Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.

Frontiers in bioengineering and biotechnology
2020-02-07 | Journal article
DOI: 10.3389/fbioe.2020.00049
PMID: 32117929
PMC: PMC7020774
Source: Self-asserted source
Benjamin Salzer

A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells.

Scientific reports
2018-11-28 | Journal article
DOI: 10.1038/s41598-018-36055-2
PMID: 30487534
PMC: PMC6261951
Source: Self-asserted source
Benjamin Salzer

Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles.

Aging
2016-01-01 | Journal article
DOI: 10.18632/aging.100865
PMID: 26752347
PMC: PMC4761711
Source: Self-asserted source
Benjamin Salzer

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.

Bone
2015-05-28 | Journal article
DOI: 10.1016/j.bone.2015.05.027
PMID: 26026730
Source: Self-asserted source
Benjamin Salzer
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