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Scopus Author ID: 56937964100

Keywords

Medicinal chemistry, Deuterium chemistry, Radiochemistry, Carbon-14, Organic synthesis

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Employment (1)

Korea Institute of Radiological and Medical Sciences: Nowon-gu, Seoul, KR

2018-09-01 to 2020-08-31 | Postdoctoral fellow (RI applied research team)
Employment
Source: Self-asserted source
Ahmed Karam Farag

Education and qualifications (3)

Atlanta English Institute: Atlanta, GA, US

Diploma
Education
Source: Self-asserted source
Ahmed Karam Farag

Korea Institute of Science and Technology: Seongbuk-gu, Seoul, KR

2014-09-01 to 2018-08-31 | Ph.D. (chemical kinomics center)
Education
Source: Self-asserted source
Ahmed Karam Farag

Mansoura University Faculty of Pharmacy: Mansoura, Dakahlia, EG

2003-09-01 to 2008-05-31 | B.Sc.
Education
Source: Self-asserted source
Ahmed Karam Farag

Works (12)

Porphyrin-Based Brain Tumor-Targeting Agents: [64Cu]Cu-porphyrin and [64Cu]Cu-TDAP

Molecular Pharmaceutics
2023-11-06 | Journal article
DOI: 10.1021/acs.molpharmaceut.3c00704
Contributors: Changkeun Im; Jae Hun Ahn; Ahmed K. Farag; Soyeon Kim; Jung Young Kim; Yong Jin Lee; Ji-Ae Park; Choong Mo Kang
Source: check_circle
Crossref

Design, synthesis, and biological evaluation of novel pyrido-dipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells

Bioorganic Chemistry
2022 | Journal article
DOI: 10.1016/j.bioorg.2022.105752
EID:

2-s2.0-85126878413

Part of ISSN: 10902120 00452068
Contributors: Abdelgawad, M.A.; Mohamed, F.E.A.; Lamie, P.F.; Bukhari, S.N.A.; Al-Sanea, M.M.; Musa, A.; Elmowafy, M.; Nayl, A.A.; Karam Farag, A.; Ali, S.M. et al.
Source: Self-asserted source
Ahmed Karam Farag via Scopus - Elsevier

AF8c, a Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer Cells

Cancers
2022-06 | Journal article | Author
DOI: 10.3390/cancers14133043
Contributors: Soyeon Jeong; Ahmed Karam Farag; Hye Kyeong Yun; Yoon A. Jeong; Dae Yeong Kim; Min Jee Jo; Seong Hye Park; Bo Ram Kim; Jung Lim Kim; Bu Gyeom Kim et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Design, synthesis, and biological evaluation of pseudo-bicyclic pyrimidine-based compounds as potential EGFR inhibitors

Bioorganic Chemistry
2022-05-30 | Journal article
DOI: 10.1016/j.bioorg.2022.105918
Part of ISSN: 0045-2068
Source: Self-asserted source
Ahmed Karam Farag

AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells

Cancers
2021-11 | Journal article | Author
DOI: 10.3390/cancers13225849
Contributors: Hyo-Sun Gil; Jeong-Hun Lee; Ahmed Karam Farag; Ahmed Hassan; Kyung-Sook Chung; Jung-Hye Choi; Eun-Joo Roh; Kyung-Tae Lee
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery

Life
2021-10-11 | Journal article
DOI: 10.3390/life11101070
Contributors: Mohammad M. Al-Sanea; Garri Chilingaryan; Narek Abelyan; Arsen Sargsyan; Sargis Hovhannisyan; Hayk Gasparyan; Smbat Gevorgyan; Sarah Albogami; Mohammed M. Ghoneim; Ahmed K. Farag et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches

Bioorganic Chemistry
2020-07 | Journal article
DOI: 10.1016/j.bioorg.2020.104121
Part of ISSN: 0045-2068
Source: Self-asserted source
Ahmed Karam Farag
grade
Preferred source (of 3)‎

Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds

Journal of Enzyme Inhibition and Medicinal Chemistry
2020-01-01 | Journal article
DOI: 10.1080/14756366.2019.1699554
Contributors: Ahmed K. Farag; Ahmed H. E. Hassan; Byung Sun Ahn; Ki Duk Park; Eun Joo Roh
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

First-in-class DAPK1/CSF1R dual inhibitors: Discovery of 3,5-dimethoxy-N-(4-(4-methoxyphenoxy)-2-((6-morpholinopyridin-3-yl)amino)pyrimidin-5-yl)benzamide as a potential anti-tauopathies agent

European Journal of Medicinal Chemistry
2018-11-02 | Journal article
DOI: https://doi.org/10.1016/j.ejmech.2018.10.057
Source: Self-asserted source
Ahmed Karam Farag
grade
Preferred source (of 3)‎

Death‐associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes

Medicinal research reviews
2018-06-27 | Journal article
DOI: 10.1002/med.21518
Source: Self-asserted source
Ahmed Karam Farag
grade
Preferred source (of 2)‎

Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders.

Eur J Med Chem.
2017-10-04 | Journal article
DOI: 10.1016/j.ejmech.2017.10.003
Source: Self-asserted source
Ahmed Karam Farag
grade
Preferred source (of 3)‎

Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular docking.

Bioorganic & Medicinal Chemistry Letters
2015-10-02 | Journal article
DOI: 10.1016/j.bmcl.2015.10.003
Source: Self-asserted source
Ahmed Karam Farag
grade
Preferred source (of 2)‎

Peer review (19 reviews for 8 publications/grants)

Review activity for Applied sciences. (1)
Review activity for Biomedicines. (2)
Review activity for Cancers. (2)
Review activity for Gels. (1)
Review activity for International journal of molecular sciences. (5)
Review activity for Life. (1)
Review activity for Molecules. (6)
Review activity for Scientia pharmaceutica. (1)
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