Personal information

Breast Cancer, BRCA1, Breast Pathology

Biography

Roy A. Jensen, M.D. graduated from Vanderbilt University School of Medicine in 1984, and remained there to complete a residency in Anatomic Pathology and Surgical Pathology fellowship with Dr. David Page. Following his clinical training he accepted a research fellowship at the National Cancer Institute in the laboratory of Dr. Stuart Aaronson. He returned to Vanderbilt in 1991 and was appointed an Assistant Professor in the Departments of Pathology and Cell Biology. In 1996 Dr. Jensen was promoted to Associate Professor of Pathology and Cell Biology and was appointed as an investigator in the Vanderbilt-Ingram Cancer Center. 
In 2004 Dr. Jensen was appointed the William R. Jewell, M.D. Distinguished Kansas Masonic Professor, the Director of The University of Kansas Cancer Center, the Director of the Kansas Masonic Cancer Research Institute, Professor of Pathology and Laboratory Medicine, and Professor of Anatomy and Cell Biology at the University of Kansas Medical Center. Dr. Jensen is a member of several scientific and professional societies including the American Association for Cancer Research, the American Association for the Advancement of Science, the American Society for Cell Biology, the American Society for Investigative Pathology, and the United States and Canadian Academy of Pathology. He currently has over 150 scientific publications and has lectured widely on the clinical and molecular aspects of breast cancer pathology. Dr Jensen's research interests are focused on understanding the function of BRCA1 and BRCA2 and their role in breast neoplasia; and in the characterization of premalignant breast disease both at the morphologic and molecular levels.

Activities

Employment (7)

University of Kansas Medical Center: Kansas City, KS, US

2004-07-01 to present | Professor (Pathology and Laboratory Medicine)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

University of Kansas Cancer Center: Kansas City, KS, US

2004-07-01 to present | Director
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

Vanderbilt University School of Medicine: Nashville, TN, US

1996-07-01 to 2004-06-30 | Associate Professor (Pathology)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

Vanderbilt University School of Medicine: Nashville, TN, US

1991-07-01 to 1996-06-30 | Assistant Professor (Pathology)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

National Cancer Institute: Bethesda, MD, US

1988-07-01 to 1991-06-30 | Biotechnology Training Fellow (Laboratory of Cellular and Molecular Biology)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

Vanderbilt University Medical Center: Nashville, TN, US

1987-07-01 to 1988-06-30 | American Cancer Society Clinical Fellow in Surgical Pathology (Pathology)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

Vanderbilt University Medical Center: Nashville, TN, US

1984-07-01 to 1987-06-30 | Resident in Anatomic Pathology (Pathology)
Employment
Source: Self-asserted source
Roy A. Jensen, M.D.

Education and qualifications (3)

Vanderbilt University School of Medicine: Nashville, TN, US

1980-08 to 1984-05 | M.D.
Education
Source: Self-asserted source
Roy A. Jensen, M.D.

Pittsburg State University: Pittsburg, KS, US

1978-08 to 1980-07 | B.S. (Biology and Chemistry)
Education
Source: Self-asserted source
Roy A. Jensen, M.D.

Neosho County Community Junior College: Chanute, KS, US

1976-08 to 1978-05 | A.A. (Neosho County Community Junior College)
Education
Source: Self-asserted source
Roy A. Jensen, M.D.

Professional activities (2)

Association of American Cancer Institutes (AACI): Pittsburg, PA, US

2020-10-10 | Past President
Distinction
Source: Self-asserted source
Roy A. Jensen, M.D.

Association of American Cancer Institutes: Pittsburgh, Pennsylvania, US

2018-10-01 | President
Distinction
Source: Self-asserted source
Roy A. Jensen, M.D.

Funding (2)

Prevention of Triple-Negative Breast Cancer by Natural Compounds

2018-03 to 2021-02 | Award
Congressionally Directed Medical Research Programs (MD, MD, US)
GRANT_NUMBER:

BC170624P1

Source: Self-asserted source
Roy A. Jensen, M.D.

The University of Kansas Cancer Center

2012-07 to 2022-06 | Grant
National Institutes of Health (Bethesda, MD, US)
GRANT_NUMBER:

P30 CA168524-06

Source: Self-asserted source
Roy A. Jensen, M.D.

Works (15)

Differential Remodeling of the BRCA1 Interactome by a Unique Minimal Clinical Truncation Mutation

2024-12-02 | Preprint
Contributors: Jingjing Chen; Mihaela E. Sardiu; Michaella J. Rekowski; Jules Nde; Zachary S. Clark; Shrikant Anant; Michael P. Washburn; Roy A. Jensen
Source: check_circle
Crossref

Cancer Prevention Perspective: The University of Kansas Cancer Center

Cancer Prevention Research
2023-12-01 | Journal article
Contributors: Roy A. Jensen; Christie A. Befort
Source: check_circle
Crossref

Understanding and Overcoming Immunosuppression Shaped by Cancer Stem Cells

Cancer Research
2023-07-05 | Journal article
Contributors: Linheng Li; Roy A. Jensen
Source: check_circle
Crossref

Leadership Diversity and Development in the Nation’s Cancer Centers

JNCI: Journal of the National Cancer Institute
2022-09-09 | Journal article
Contributors: Caryn Lerman; Chanita Hughes-Halbert; Mary Falcone; David M Gosky; Roy A Jensen; Kelvin P Lee; Edith Mitchell; Kunle Odunsi; Jennifer W Pegher; Elisa Rodriguez et al.
Source: check_circle
Crossref

Honokiol Affects Stem Cell Viability by Suppressing Oncogenic YAP1 Function to Inhibit Colon Tumorigenesis

Cells
2021-06-26 | Journal article
Contributors: Dharmalingam Subramaniam; Sivapriya Ponnurangam; Satish Ramalingam; Deep Kwatra; Prasad Dandawate; Scott J. Weir; Shahid Umar; Roy A. Jensen; Shrikant Anant
Source: check_circle
Crossref
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Preferred source (of 2)‎

Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells

Biomedicines
2021-04-28 | Journal article
Contributors: Prabhu Ramamoorthy; Prasad Dandawate; Roy A. Jensen; Shrikant Anant
Source: check_circle
Crossref
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Preferred source (of 2)‎

Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

Scientific Reports
2020-01-28 | Journal article
Contributors: Prasad Dandawate; Dharmalingam Subramaniam; Peyton Panovich; David Standing; Balaji Krishnamachary; Gaurav Kaushik; Sufi Mary Thomas; Animesh Dhar; Scott J. Weir; Roy A. Jensen et al.
Source: check_circle
Crossref

Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lymphoma cells

Leukemia
2019-07-21 | Journal article
Contributors: Pratikkumar H. Vekaria; Amar Kumar; Dharmalingam Subramaniam; Neil Dunavin; Anusha Vallurupalli; Frank Schoenen; Siddhartha Ganguly; Shrikant Anant; Joseph P. McGuirk; Roy A. Jensen et al.
Source: check_circle
Crossref

Relevant Word Order Vectorization for Improved Natural Language Processing in Electronic Health Records

Scientific Reports
2019-06-25 | Journal article
Contributors: Jeffrey Thompson; Jinxiang Hu; Dinesh Pal Mudaranthakam; David Streeter; Lisa Neums; Michele Park; Devin C. Koestler; Byron Gajewski; Roy Jensen; Matthew S. Mayo
Source: check_circle
Crossref

BRCA1—No Matter How You Splice It

Cancer Research
2019-05-01 | Journal article
Contributors: Dan Li; Lisa M. Harlan-Williams; Easwari Kumaraswamy; Roy A. Jensen
Source: check_circle
Crossref

Targeted Therapy for EBV-Associated B-cell Neoplasms

Molecular Cancer Research
2019-04-01 | Journal article
Contributors: Siddhartha Ganguly; Sudhakiranmayi Kuravi; Satyanarayana Alleboina; Giridhar Mudduluru; Roy A. Jensen; Joseph P. McGuirk; Ramesh Balusu
Source: check_circle
Crossref

CDC37 as a novel target for the treatment of NPM1-ALK expressing anaplastic large cell lymphomas

Blood Cancer Journal
2019-01-29 | Journal article
Contributors: Sudhakiranmayi Kuravi; Elizabeth Parrott; Giridhar Mudduluru; Janice Cheng; Siddhartha Ganguly; Yogen Saunthararajah; Roy A. Jensen; Brian S. Blagg; Joseph P. McGuirk; Ramesh Balusu
Source: check_circle
Crossref

Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression

Cell Death & Disease
2018-02-27 | Journal article
Contributors: Linda Xiaoyan Li; Julie Xia Zhou; James P. Calvet; Andrew K. Godwin; Roy A. Jensen; Xiaogang Li
Source: check_circle
Crossref

When the good go bad: Mutant NPM1 in acute myeloid leukemia

Blood Reviews
2017-11 | Journal article
Source: Self-asserted source
Roy A. Jensen, M.D.
grade
Preferred source (of 2)‎

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

Seminars in Cancer Biology
2016-10 | Journal article
Contributors: Prasad R. Dandawate; Dharmalingam Subramaniam; Roy A. Jensen; Shrikant Anant
Source: check_circle
Crossref