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Scopus Author ID: 36972677700
Loop profile: 1299232

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Employment (3)

East Carolina University: Greenville, North Carolina, US

2023 to present | Assistant Professor (Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Karen Mruk

University of Wyoming College of Health Sciences: Laramie, WY, US

2018-08-22 to 2023-03 | Assistant Professor (Pharmacy)
Employment
Source: Self-asserted source
Karen Mruk

Stanford University: Stanford, CA, US

2012-08 to 2018-08 | Postdoctoral Fellow (Chemical and Systems Biology)
Employment
Source: Self-asserted source
Karen Mruk

Education and qualifications (2)

University of Massachusetts Medical School: Worcester, MA, US

2005 to 2012 | Ph.D. (Biochemistry and Molecular Pharmacology)
Education
Source: Self-asserted source
Karen Mruk

Drew University: Madison, NJ, US

1999 to 2003 | B.A.
Education
Source: Self-asserted source
Karen Mruk

Professional activities (8)

Society for Neuroscience: Washington, DC, US

2016 to present
Membership
Source: Self-asserted source
Karen Mruk

International Zebrafish Society: Milwaukee, WI, US

2016 to present
Membership
Source: Self-asserted source
Karen Mruk

Genetics Society of America: Bethesda, MD, US

2015 to present
Membership
Source: Self-asserted source
Karen Mruk

Society for Developmental Biology: Rockville, MD, US

2014 to present
Membership
Source: Self-asserted source
Karen Mruk

American Association For The Advancement of Science: Washington D.C., District of Columbia, US

2007 to present
Membership
Source: Self-asserted source
Karen Mruk

University of Washington Medical School: Seattle, WA, US

2018 to 2023 | Affiliated Faculty (Pharmacology)
Invited position
Source: Self-asserted source
Karen Mruk

Biophysical Society: Rockville, MD, US

2006 to 2012
Membership
Source: Self-asserted source
Karen Mruk

Society of Cosmetic Chemists: New York, New York, US

2003 to 2005
Membership
Source: Self-asserted source
Karen Mruk

Works (17)

Non-invasive single cell aptasensing in live cells and animals

Chemical Science
2024 | Journal article
DOI: 10.1039/D3SC05735F
Contributors: Eiman A. Osman; Thomas P. Rynes; Y. Lucia Wang; Karen Mruk; Maureen McKeague
Source: check_circle
Crossref

A mutualistic model bacterium is lethal to non-symbiotic hosts via the type VI secretion system

2024-12-14 | Preprint
DOI: 10.1101/2024.12.13.628426
Contributors: Keegan E. Gaddy; Alecia N. Septer; Karen Mruk; Morgan E. Milton
Source: check_circle
Crossref

Effect of Voltage-Gated K+Channel Inhibition by 4-aminopyridine in Spinal Cord Injury Recovery in Zebrafish

2024-07-18 | Preprint
DOI: 10.1101/2024.07.15.603582
Contributors: Payge M. Hoffman; Karen Mruk
Source: check_circle
Crossref

Differential Roles of Diet on Development and Spinal Cord Regeneration in Larval Zebrafish.

Zebrafish
2024-04-01 | Journal article | Author
DOI: 10.1089/zeb.2023.0042
PMID: 38621204
Contributors: Purifoy EJ; Karen Mruk
Source: Self-asserted source
Karen Mruk

Effects of age on the response to spinal cord injury: optimizing the larval zebrafish model

2023-05-18 | Preprint
DOI: 10.1101/2023.05.18.541337
Contributors: Whitney J. Walker; Kirsten L. Underwood; Patrick I. Garrett; Kathryn B. Lorbacher; Shannon M. Linch; Thomas P. Rynes; Chloe Sloop; Karen Mruk
Source: check_circle
Crossref

Aquatic Freshwater Vertebrate Models of Epilepsy Pathology: Past Discoveries and Future Directions for Therapeutic Discovery

International Journal of Molecular Sciences
2022-08-03 | Journal article
DOI: 10.3390/ijms23158608
Contributors: Rachel E. Williams; Karen Mruk
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Targeted cell ablation in zebrafish using optogenetic transcriptional control

Development
2020-01-01 | Journal article
DOI: 10.1242/dev.183640
Contributors: Karen Mruk; Paulina Ciepla; Patrick A. Piza; Mohammad A. Alnaqib; James K. Chen
Source: check_circle
Crossref

Targeted cell ablation in zebrafish using optogenetic transcriptional control

2019-08-10 | Other
DOI: 10.1101/730507
Contributors: Karen Mruk; Paulina Ciepla; Patrick A. Piza; Mohammad A. Alnaqib; James K. Chen
Source: check_circle
Crossref

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

Nature Communications
2018-10-02 | Journal article
DOI: 10.1038/s41467-018-06447-z
Contributors: Sunhee Hwang; Karen Mruk; Simin Rahighi; Andrew G. Raub; Che-Hong Chen; Lisa E. Dorn; Naoki Horikoshi; Soichi Wakatsuki; James K. Chen; Daria Mochly-Rosen
Source: check_circle
Crossref

Mutant SOD1 protein increases Na<inf>v</inf>1.3 channel excitability

Journal of Biological Physics
2016 | Journal article
DOI: 10.1007/s10867-016-9411-x
EID:

2-s2.0-84963705385
Contributors: Kubat Öktem, E.; Mruk, K.; Chang, J.; Akin, A.; Kobertz, W.R.; Brown, R.H.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Bioreactive tethers

Advances in Experimental Medicine and Biology
2015 | Book
DOI: 10.1007/978-1-4939-2845-3_5
EID:

2-s2.0-84950301439
Contributors: Mruk, K.; Kobertz, W.R.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Thinking big with small molecules

Journal of Cell Biology
2015 | Journal article
DOI: 10.1083/jcb.201501084
EID:

2-s2.0-84928243595
Contributors: Mruk, K.; Chen, J.K.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Calmodulation meta-analysis: Predicting calmodulin binding via canonical motif clustering

Journal of General Physiology
2014 | Journal article
DOI: 10.1085/jgp.201311140
EID:

2-s2.0-84903776436
Contributors: Mruk, K.; Farley, B.M.; Ritacco, A.W.; Kobertz, W.R.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Structural insights into neuronal K <sup>+</sup> channel-calmodulin complexes

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
DOI: 10.1073/pnas.1207606109
EID:

2-s2.0-84865301814
Contributors: Mruk, K.; Shandilya, S.M.D.; Blaustein, R.O.; Schiffer, C.A.; Kobertz, W.R.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Xenopus laevis oocytes infected with multi-drug-resistant bacteria: Implications for electrical recordings

Journal of General Physiology
2011 | Journal article
DOI: 10.1085/jgp.201110661
EID:

2-s2.0-79961103086
Contributors: O'Connell, D.; Mruk, K.; Rocheleau, J.M.; Kobertz, W.R.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Discovery of a novel activator of KCNQ1-KCNE1 K± channel complexes

PLoS ONE
2009 | Journal article
DOI: 10.1371/journal.pone.0004236
EID:

2-s2.0-58849099205
Contributors: Mruk, K.; Kobertz, W.R.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis

Proceedings of the National Academy of Sciences of the United States of America
2005 | Journal article
DOI: 10.1073/pnas.0507329102
EID:

2-s2.0-29144496895
Contributors: Clancy, L.; Mruk, K.; Archer, K.; Woelfel, M.; Mongkolsapaya, J.; Screaton, G.; Lenardo, M.J.; Chan, F.K.-M.
Source: Self-asserted source
Karen Mruk via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Communications biology. (1)
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