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Activities

Employment (3)

Peking University: Beijing, CN

2020-12-01 to present
Employment
Source: Self-asserted source
Aili Fan

Beijing University of Chemical Technology: Beijing, Beijing, CN

2017-09-01 to 2020-11-30
Employment
Source: Self-asserted source
Aili Fan

Institute of Microbiology: Beijing, CN

2015-10-01 to 2017-08-31
Employment
Source: Self-asserted source
Aili Fan

Education and qualifications (2)

Philipps-Universität Marburg: Marburg, Hessen, DE

2011-09-01 to 2015-08
Education
Source: Self-asserted source
Aili Fan

Peking University: Beijing, Beijing, CN

2005-09-01 to 2011-08
Education
Source: Self-asserted source
Aili Fan

Works (45)

Global analysis of fungal biosynthetic gene clusters reveals the diversification of diketopiperazine biosynthesis

Bioresource Technology
2025-04 | Journal article
Contributors: Bin Wei; Ti-Ti Ying; Hua-Wei Lv; Zhen-Yi Zhou; Hai Cai; Gang-Ao Hu; Hui-Min Liang; Wen-Chao Yu; Yan-Lei Yu; Ai-Li Fan et al.
Source: check_circle
Crossref

Three-dimensional structural alignment based discovery and molecular basis of AtoB, catalyzing linear tetracyclic formation

Chemical Science
2024 | Journal article
Contributors: Ke Ma; Jie Liu; Zequan Huang; Mengyue Wu; Dong Liu; Jinwei Ren; Aili Fan; Wenhan Lin
Source: check_circle
Crossref

Target Discovery of Dhilirane-Type Meroterpenoids by Biosynthesis Guidance and Tailoring Enzyme Catalysis

Journal of the American Chemical Society
2024-11-06 | Journal article
Contributors: Zhaolun Sun; Mengyue Wu; Boyuan Zhong; Jingshuai Wu; Dong Liu; Jinwei Ren; Shilong Fan; Wenhan Lin; Aili Fan
Source: check_circle
Crossref

Discovery of a Hybrid Molecule with Phytotoxic Activity by Genome Mining, Heterologous Expression, and OSMAC Strategy

Journal of Agricultural and Food Chemistry
2024-08-21 | Journal article
Contributors: Yubo Lu; Yanpeng Li; Min Dou; Dong Liu; Wenhan Lin; Aili Fan
Source: check_circle
Crossref

Nucleobase-Coupled Xanthones with Anti-ROS Effects from Marine-Derived Fungus Aspergillus sydowii

The Journal of Organic Chemistry
2024-06-07 | Journal article
Contributors: Rui Ge; Xingchen Guo; Hongli Jia; Jing Zhang; Aili Fan; Dong Liu; Jian Huang; Wenhan Lin
Source: check_circle
Crossref

Mining the biosynthetic landscape of lactic acid bacteria unearths a new family of RiPPs assembled by a novel type of ThiF-like adenylyltransferases

2024-05-13 | Preprint
Contributors: Mengjiao Wang; Mengyue Wu; Meng Han; Xiaogang Niu; Aili Fan; Shaozhou Zhu; Yigang Tong
Source: check_circle
Crossref

Biosynthesis of Epipyrone A Reveals a Highly Specific Membrane-Bound Fungal C-Glycosyltransferase for Pyrone Galactosylation

Organic Letters
2024-02-16 | Journal article
Contributors: Aili Fan; Boyuan Zhong; Dong Liu; Yubo Lu; Mengyue Wu; Hongwei Jin; Xiao-Meng Shi; Jinwei Ren; Bo Zhang; Xiao-dong Su et al.
Source: check_circle
Crossref

Brominated Depsidones with Antibacterial Effects from a Deep-Sea-Derived Fungus Spiromastix sp.

Marine Drugs
2024-02-03 | Journal article
Contributors: Zequan Huang; Dong Liu; Shang Chen; Jinwei Ren; Chenghai Gao; Zhiyong Li; Aili Fan; Wenhan Lin
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Unequivocal identification of two-bond heteronuclear correlations in natural products at nanomole scale by i-HMBC

Nature Communications
2023-04-03 | Journal article
Part of ISSN: 2041-1723
Contributors: Yunyi Wang; Aili Fan; Ryan Cohen; Guilherme Dal Poggetto; Zheng Huang; Haifeng Yang; Gary E. Martin; Edward Sherer; Mikhail Reibarkh; Xiao Wang
Source: Self-asserted source
Aili Fan

Mammalian Commensal <i>Streptococci</i> Utilize a Rare Family of Class VI Lanthipeptide Synthetases to Synthesize Miniature Lanthipeptide-type Ribosomal Peptide Natural Products

Biochemistry
2023-01-17 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Yile He; Aili Fan; Meng Han; Hongwei Li; Mengzhe Li; Huahao Fan; Xiaoping An; Lihua Song; Shaozhou Zhu; Yigang Tong
Source: Self-asserted source
Aili Fan

Versicotide G suppresses osteoclastogenesis and prevents osteolysis

Bioorganic Chemistry
2022-12 | Journal article
Part of ISSN: 0045-2068
Contributors: He Zhang; Ying Kang; Xinyi Qi; Jingshuai Wu; Dong Liu; Aili Fan; Jian Huang; Wenhan Lin
Source: Self-asserted source
Aili Fan

Concise Biosynthesis of Tropone-Containing Spiromaterpenes by a Sesquiterpene Cyclase and a Multifunctional P450 from a Deep-Sea-Derived <i>Spiromastix</i> sp. Fungus

Journal of Natural Products
2022-12-23 | Journal article | Author
Part of ISSN: 0163-3864
Part of ISSN: 1520-6025
Contributors: Jie Liu; Xiang Guo; Xingchen Guo; Boyuan Zhong; Tao Wang; Dong Liu; Hongwei Jin; Jinwei Ren; Zihe Liu; Jiangtao Gao et al.
Source: Self-asserted source
Aili Fan

Prenylated notoamide-type alkaloids isolated from the fungus Aspergillus sclerotiorum and their inhibition of NLRP3 inflammasome activation and antibacterial activities

Phytochemistry
2022-11 | Journal article
Part of ISSN: 0031-9422
Contributors: Qinyu Meng; Xiang Guo; Jingshuai Wu; Dong Liu; Yu-Cheng Gu; Jian Huang; Aili Fan; Wenhan Lin
Source: Self-asserted source
Aili Fan

Acorane sesquiterpenes from the deep-sea derived Penicillium bilaiae fungus with anti-neuroinflammatory effects

Frontiers in Chemistry
2022-11-23 | Journal article
Part of ISSN: 2296-2646
Contributors: Wenfang Zhang; Qingyu Meng; Jingshuai Wu; Wei Cheng; Dong Liu; Jian Huang; Aili Fan; Jing Xu; Wenhan Lin
Source: Self-asserted source
Aili Fan

Eremophilane-Type Sesquiterpenes from a Marine-Derived Fungus Penicillium Copticola with Antitumor and Neuroprotective Activities

Marine Drugs
2022-11-13 | Journal article
Contributors: Jianping Zhang; Dong Liu; Aili Fan; Jian Huang; Wenhan Lin
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Sclerotiamides C–H, Notoamides from a Marine Gorgonian-Derived Fungus with Cytotoxic Activities

Journal of Natural Products
2022-04-22 | Journal article
Contributors: Xiang Guo; Qinyu Meng; Jie Liu; Jingshuai Wu; Hongli Jia; Dong Liu; Yucheng Gu; Jianrong Liu; Jian Huang; Aili Fan et al.
Source: check_circle
Crossref

Rapid colonization and biodegradation of untreated commercial polyethylene wrap by a new strain of Bacillus velezensis C5

Journal of Environmental Management
2022-01 | Journal article
Contributors: Xianrui Liu; Yiming Zhang; Qiufeng Sun; Zihan Liu; Yilin Zhao; Aili Fan; Haijia Su
Source: check_circle
Crossref

Chlorinated metabolites with antibacterial activities from a deep-sea-derived <i>Spiromastix</i> fungus

RSC Advances
2021 | Journal article
Part of ISSN: 2046-2069
Contributors: Siwen Niu; Dong Liu; Zongze Shao; Jian Huang; Aili Fan; Wenhan Lin
Source: Self-asserted source
Aili Fan

Chemical epigenetic manipulation triggers the production of sesquiterpenes from the deep-sea derived Eutypella fungus

Phytochemistry
2021-12 | Journal article
Part of ISSN: 0031-9422
Contributors: Siwen Niu; Dong Liu; Zongze Shao; Jianrong Liu; Aili Fan; Wenhan Lin
Source: Self-asserted source
Aili Fan

ThpacC Acts as a Positive Regulator of Homodimericin A Biosynthesis and Antifungal Activities of Trichoderma harzianum 3.9236

Journal of Agricultural and Food Chemistry
2021-11-03 | Journal article
Contributors: Mengyue Wu; Huiling Wei; Ke Ma; Peiqi Cui; Shaozhou Zhu; Daowan Lai; Jinwei Ren; Wenzhao Wang; Aili Fan; Wenhan Lin et al.
Source: check_circle
Crossref

Discovery of cyclohexadepsipeptides with anti-Zika virus activities and biosynthesis of the nonproteinogenic building block (3S)-methyl-l-proline

Journal of Biological Chemistry
2021-07 | Journal article
Part of ISSN: 0021-9258
Contributors: Bochuan Yuan; Ziwei Wu; Wei Ji; Dong Liu; Xiang Guo; Donghui Yang; Aili Fan; Hongli Jia; 马明; Wenhan Lin
Source: Self-asserted source
Aili Fan

Epigenetic Manipulation to Trigger Production of Guaiane-Type Sesquiterpenes from a Marine-Derived <i>Spiromastix</i> sp. Fungus with Antineuroinflammatory Effects

Journal of Natural Products
2021-07-23 | Journal article
Part of ISSN: 0163-3864
Part of ISSN: 1520-6025
Contributors: Xiang Guo; Qinyu Meng; Siwen Niu; Jie Liu; Xingchen Guo; Zhaolun Sun; Dong Liu; Yu-Cheng Gu; Jian Huang; Aili Fan et al.
Source: Self-asserted source
Aili Fan

Recombinant protein production in the filamentous fungus Trichoderma

Chinese Journal of Chemical Engineering
2021-02 | Journal article
Contributors: Huiling Wei; Mengyue Wu; Aili Fan; Haijia Su
Source: check_circle
Crossref

Ustethylin Biosynthesis Implies Phenethyl Derivative Formation in <i>Aspergillus ustus</i>

Organic Letters
2020-10-16 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Contributors: Liujuan Zheng; Yiling Yang; Haowen Wang; Aili Fan; Liping Zhang; Shu-Ming Li
Source: Self-asserted source
Aili Fan

Oxepinamide F biosynthesis involves enzymatic d-aminoacyl epimerization, 3H-oxepin formation, and hydroxylation induced double bond migration

Nature Communications
2020-10-01 | Journal article
Contributors: Liujuan Zheng; Haowen Wang; Aili Fan; Shu-Ming Li
Source: check_circle
Crossref

Reinvestigation of the substrate specificity of a reverse prenyltransferase NotF from Aspergillus sp. MF297-2

Archives of Microbiology
2020-08 | Journal article
Contributors: Keyan Yang; Shu-Ming Li; Xiaoqing Liu; Aili Fan
Source: check_circle
Crossref

Enhanced resistance of Trichoderma harzianum LZDX-32-08 to hygromycin B induced by sea salt

Biotechnology Letters
2020-08-26 | Journal article
Part of ISSN: 0141-5492
Part of ISSN: 1573-6776
Source: Self-asserted source
Aili Fan
grade
Preferred source (of 2)‎

Enhancing robustness of aerobic granule sludge under low C/N ratios with addition of kitchen wastewater

Journal of Environmental Management
2020-07 | Journal article
Part of ISSN: 0301-4797
Source: Self-asserted source
Aili Fan

New perspectives on the treatment of mycobacterial infections using antibiotics

Applied Microbiology and Biotechnology
2020-05 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Source: Self-asserted source
Aili Fan

Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi

Chemical Science
2018 | Journal article
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Source: Self-asserted source
Aili Fan

Switching a regular tryptophan C4-prenyltransferase to a reverse tryptophan-containing cyclic dipeptide C3-prenyltransferase by sequential site-directed mutagenesis

Organic & Biomolecular Chemistry
2018 | Journal article
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Aili Fan

A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici

Molecular Microbiology
2017-08 | Journal article
Part of ISSN: 0950-382X
Source: Self-asserted source
Aili Fan

Deletion of a Histone Acetyltransferase Leads to the Pleiotropic Activation of Natural Products in Metarhizium robertsii

Organic Letters
2017-04-07 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Aili Fan

Saturation mutagenesis on Arg244 of the tryptophan C4-prenyltransferase FgaPT2 leads to enhanced catalytic ability and different preferences for tryptophan-containing cyclic dipeptides

Applied Microbiology and Biotechnology
2016-06 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Source: Self-asserted source
Aili Fan

Tryptophan prenyltransferases showing higher catalytic activities for Friedel–Crafts alkylation of o- and m-tyrosines than tyrosine prenyltransferases

Organic & Biomolecular Chemistry
2015 | Journal article
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Aili Fan

Impacts and perspectives of prenyltransferases of the DMATS superfamily for use in biotechnology

Applied Microbiology and Biotechnology
2015-09 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Source: Self-asserted source
Aili Fan

Prenyltransferases as key enzymes in primary and secondary metabolism

Applied Microbiology and Biotechnology
2015-09 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Source: Self-asserted source
Aili Fan

Site-directed Mutagenesis Switching a Dimethylallyl Tryptophan Synthase to a Specific TyrosineC3-Prenylating Enzyme

Journal of Biological Chemistry
2015-01-16 | Journal article
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Aili Fan

A new member of the DMATS superfamily from Aspergillus niger catalyzes prenylations of both tyrosine and tryptophan derivatives

Applied Microbiology and Biotechnology
2014-12 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Source: Self-asserted source
Aili Fan

Prenylation of tyrosine and derivatives by a tryptophan C7-prenyltransferase

Tetrahedron Letters
2014-09 | Journal article
Part of ISSN: 0040-4039
Source: Self-asserted source
Aili Fan

One Substrate - Seven Products with Different Prenylation Positions in One-Step Reactions: Prenyltransferases Make it Possible

Advanced Synthesis & Catalysis
2013-09-16 | Journal article
Part of ISSN: 1615-4150
Source: Self-asserted source
Aili Fan

New Insights into the Biosynthesis of Prenylated Xanthones: Xptb fromAspergillus nidulansCatalyses an O-Prenylation of Xanthones

ChemBioChem
2012-12-21 | Journal article
Part of ISSN: 1439-4227
Source: Self-asserted source
Aili Fan

Recent progress in the research on lamellarins and related pyrrole-derived alkaloids from marine organisms

Journal of Chinese Pharmaceutical Sciences
2011-09-20 | Journal article
Part of ISSN: 1003-1057
Source: Self-asserted source
Aili Fan

Total Synthesis of Lamellarins D, H, and R and Ningalin B

Organic Letters
2011-01-21 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Aili Fan

One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone

Organic Letters
2010-09-17 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Aili Fan

Peer review (7 reviews for 5 publications/grants)

Review activity for Bioresources and bioprocessing. (1)
Review activity for Fitoterapia. (1)
Review activity for Journal of agricultural and food chemistry. (2)
Review activity for Journal of natural products. (2)
Review activity for Journal of the American Chemical Society. (1)