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Centre for Evidence in Transplantation

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ResearcherID: J-9739-2013
Scopus Author ID: 7202603562

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Employment (1)

University of Oxford: Oxford, GB

2018-01-01 to present | Associate Professor (Nuffield Department of Surgical Sciences)
Employment
Source: Self-asserted source
Simon R Knight

Education and qualifications (2)

University of Cambridge: Cambridge, GB

2009-04-01 to present | MChir (Medical School)
Education
Source: Self-asserted source
Simon R Knight

University of Cambridge: Cambridge, GB

1997-09-01 to 2002-02-01 | MB BChir (Medical School)
Education
Source: Self-asserted source
Simon R Knight

Funding (10)

Real-world AI-based iBox algorithm test: predicting long-term renal allograft survival, driving accurate, rapid clinical decision making, contributing to prolonged graft lifespan.

2023-09-01 to 2026-08-31 | Grant
National Institute for Health and Care Research (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.13891312
GRANT_NUMBER: AI_AWARD02601
Source: Self-asserted source
Simon R Knight via DimensionsWizard

Oxygenated Hypothermic Machine Perfusion in Pancreas Preservation for Transplantation

2023-07-01 to 2026-06-30 | Grant
National Institute for Health and Care Research (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.13891323
GRANT_NUMBER: NIHR204643
Source: Self-asserted source
Simon R Knight via DimensionsWizard

Explainable machine learning models for clinical decision making in organ offers for transplant

2023-04 to present | Grant
University of Oxford (Oxford, GB)
Source: Self-asserted source
Simon R Knight

Explainable machine learning models for clinical decision support in kidney transplant offering

2021-11-01 to 2023-04-30 | Grant
National Institute for Health and Care Research (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.12903115
GRANT_NUMBER: AI_AWARD02316
Source: Self-asserted source
Simon R Knight via DimensionsWizard

Should we ligate haemodialysis fistulas in patients once they have been transplanted successfully?

2021-06 to 2023-06 | Grant
NIHR RfPB (London, GB)
GRANT_NUMBER:

NIHR202255
Source: Self-asserted source
Simon R Knight

Defatting of donor transplant livers during normothermic perfusion – a randomised clinical trial

2021-02 to present | Grant
NIHR EME (Southampton, GB)
GRANT_NUMBER:

NIHR131163
Source: Self-asserted source
Simon R Knight

Normothermic machine perfusion of transplant donor livers: making every donation count (the PLUS study).

2020-07 to present | Grant
NIHR (London, GB)
GRANT_NUMBER:

NIHR201003
Source: Self-asserted source
Simon R Knight

Normothermic preservation and repair of transplant donor kidneys

2019-08 to 2023-08 | Grant
NIHR (London, GB)
GRANT_NUMBER:

NIHR200022
Source: Self-asserted source
Simon R Knight

Surveillance of arteriovenous fistulae using ultrasound (SONAR).

2018-08 to 2022-08 | Grant
NIHR (London, GB)
GRANT_NUMBER:

NIHR135572
Source: Self-asserted source
Simon R Knight

James Lind Alliance Priorities Setting Partnership in Kidney Transplantation

2013-10 to 2015-10 | Grant
NIHR Oxford Musculoskeletal Biomedical Research Centre (Oxford, GB)
URL: https://www.transplantpsp.org/kidney/
Source: Self-asserted source
Simon R Knight

Works (50 of 115)

Items per page:
Page 1 of 3

A Trusted Friend in the Middle of the Night: End-User Perspectives on Artificial Intelligence Informed Software Systems as a Decision-Making Aid for Patients and Clinicians Navigating Uncertainty in Kidney Transplant

2025 | Book chapter
DOI: 10.1007/978-3-031-80889-0_14
Contributors: Laura R. Wingfield; Katie Wainwright; Simon Knight; Helena Webb
Source: check_circle
Crossref

Prolonged normothermic perfusion of the kidney – a historically controlled, phase 1 cohort study

2024-08-16 | Preprint
DOI: 10.21203/rs.3.rs-4687115/v1
Contributors: Richard Dumbill; Simon Knight; James Hunter; John Fallon; Daniel Voyce; Jacob Barrett; Matthew Ellen; Elizabeth Conroy; Ian Roberts; Tim James et al.
Source: check_circle
Crossref

Predicting graft and patient outcomes following kidney transplantation using interpretable machine learning models.

Scientific reports
2024-07 | Journal article
DOI: 10.1038/s41598-024-66976-0
PMID: 39075081
PMC: PMC11286929
Contributors: Salaün A; Knight S; Wingfield L; Zhu T
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2024-07 | Journal article
DOI: 10.3389/ti.2024.13457
PMID: 39104836
PMC: PMC11298349
Contributors: O'Callaghan JM; Knight S; Fallon J
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Defatting of donor transplant livers during normothermic perfusion-a randomised clinical trial: study protocol for the DeFat study.

Trials
2024-06 | Journal article
DOI: 10.1186/s13063-024-08189-4
PMID: 38886851
PMC: PMC11181618
Contributors: Abbas SH; Ceresa CDL; Hodson L; Nasralla D; Watson CJE; Mergental H; Coussios C; Kaloyirou F; Brusby K; Mora A et al.
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Doppler ultrasound surveillance of recently formed haemodialysis arteriovenous fistula: the SONAR observational cohort study.

Health technology assessment (Winchester, England)
2024-05 | Book
DOI: 10.3310/ytbt4172
PMID: 38768043
Contributors: Richards J; Summers D; Sidders A; Allen E; Ayaz Hossain M; Paul S; Slater M; Bartlett M; Lagaac R; Laing E et al.
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2024-04 | Journal article
DOI: 10.3389/ti.2024.13111
PMID: 38736987
PMC: PMC11082344
Contributors: Knight SR; O'Callaghan JM
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys.

Blood
2024-02 | Journal article
DOI: 10.1182/blood.2023022385
PMID: 38048591
PMC: PMC10900257
Contributors: Dumbill R; Rabcuka J; Fallon J; Knight S; Hunter J; Voyce D; Barrett J; Ellen M; Weissenbacher A; Kurniawan T et al.
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2024-02 | Journal article
DOI: 10.3389/ti.2024.12711
PMID: 38389709
PMC: PMC10883077
Contributors: Knight SR; O'Callaghan JM
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2024-01 | Journal article
DOI: 10.3389/ti.2024.12597
PMID: 38317691
PMC: PMC10839004
Contributors: O'Callaghan JM; Knight SR
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Cardiorespiratory Optimisation by Arteriovenous fistula Ligation after renal Transplantation (COBALT): Study protocol for a multicentre randomised interventional feasibility trial

BMJ Open
2023 | Journal article
DOI: 10.1136/bmjopen-2022-067668
EID:

2-s2.0-85147791641

Part of ISSN: 20446055
Contributors: Surendrakumar, V.; Aitken, E.; Mark, P.; Motallebzadeh, R.; Hunter, J.; Amer, A.; Summers, D.; Rennie, K.; Rooshenas, L.; Garbi, M. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

DIFFUSION-LIMITED O<sub>2</sub> RELEASE IN HUMAN KIDNEYS PERFUSED WITH STORED BLOOD

medRxiv
2023 | Other
DOI: 10.1101/2023.05.07.23289584
EID:

2-s2.0-85161399076
Contributors: Dumbill, R.; Rabcuka, J.; Knight, S.; Hunter, J.; Fallon, J.; Voyce, D.; Barrett, J.; Ellen, M.; Weissenbacher, A.; Kurniawan, T. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Pancreas transplantation

Surgery (United Kingdom)
2023 | Journal article
DOI: 10.1016/j.mpsur.2023.06.008
EID:

2-s2.0-85166649698

Part of ISSN: 18781764 02639319
Contributors: Knight, S.; Vogel, T.; Friend, P.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Pre-emptive living donor kidney transplantation: A public health justification to change the default

Frontiers in Public Health
2023 | Journal article
DOI: 10.3389/fpubh.2023.1124453
EID:

2-s2.0-85151377741

Part of ISSN: 22962565
Contributors: Kim, I.; Maggiore, U.; Knight, S.R.; Rana Magar, R.; Pengel, L.H.M.; Dor, F.J.M.F.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Sir Peter J. Morris, AC, FRS, FMedSci, FRCP, FRCS

Transplantation
2023 | Journal article
DOI: 10.1097/TP.0000000000004635
EID:

2-s2.0-85163126693

Part of ISSN: 00411337
Contributors: Russell, P.S.; Wood, K.; Montgomery, R.A.; Pestana, J.M.; West, L.J.; Dallman, M.; Quiroga, I.; Suthanthiran, M.S.; Coomer, M.; Pengel, L. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2023 | Journal article
DOI: 10.3389/ti.2023.11574
EID:

2-s2.0-85163286997

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2023 | Journal article
DOI: 10.3389/ti.2023.11129
EID:

2-s2.0-85148294418

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Trends in systematic reviews of kidney transplantation: A 10-year analysis of the evidence base

Transplantation Reviews
2023 | Journal article
DOI: 10.1016/j.trre.2023.100759
EID:

2-s2.0-85151551913

Part of ISSN: 15579816 0955470X
Contributors: Salih, S.; O'Callaghan, J.; Salih, M.; Walker, J.; Magar, R.R.; Knight, S.; Pengel, L.H.M.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2023-12 | Journal article
DOI: 10.3389/ti.2023.12423
PMID: 38149082
PMC: PMC10749957
Contributors: Knight SR
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

What are the benefits of preemptive versus non-preemptive kidney transplantation? A systematic review and meta-analysis.

Transplantation reviews (Orlando, Fla.)
2023-09 | Journal article
DOI: 10.1016/j.trre.2023.100798
PMID: 37801855
Contributors: Rana Magar R; Knight SR; Maggiore U; Lafranca JA; Dor FJMF; Pengel LHM
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Predicting graft and patient outcomes following kidney transplantation using interpretable machine learning models

2023-08 | Preprint
DOI: 10.1101/2023.08.24.23294535
PPR: PPR704857
Contributors: Salaün A; Knight S; Wingfield L; Zhu T
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch.

Transplant international : official journal of the European Society for Organ Transplantation
2023-08 | Journal article
DOI: 10.3389/ti.2023.11816
PMID: 37621983
PMC: PMC10444948
Contributors: Knight SR
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Clinical Decision Support Systems Used in Transplantation: Are They Tools for Success or an Unnecessary Gadget? A Systematic Review.

Transplantation
2023-05-05 | Journal article
DOI: 10.1097/tp.0000000000004627
PMID: 37143191
Contributors: Wingfield LR; Salaun A; Khan A; Webb H; Zhu T; Knight S
Source: Self-asserted source
Simon R Knight

Transplant Trial Watch

Transplant international : official journal of the European Society for Organ Transplantation
2023-01 | Journal article
PMC: PMC9928744
Contributors: Knight S
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch

Transplant international : official journal of the European Society for Organ Transplantation
2023-01 | Journal article
PMC: PMC10287831
Contributors: Knight S
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch

Transplant international : official journal of the European Society for Organ Transplantation
2023-01 | Journal article
PMC: PMC10565800
Contributors: O’Callaghan J; Knight S
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch

Transplant international : official journal of the European Society for Organ Transplantation
2023-01 | Journal article
PMC: PMC10627797
Contributors: Knight S; Fallon J; Mentor K
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

Transplant Trial Watch

Transplant international : official journal of the European Society for Organ Transplantation
2023-01 | Journal article
PMC: PMC10679324
Contributors: O’Callaghan J; Knight S
Source: Self-asserted source
Simon R Knight via Europe PubMed Central

How good is a living donor? Systematic review and meta-analysis of the effect of donor demographics on post kidney transplant outcomes

Journal of Nephrology
2022 | Journal article
DOI: 10.1007/s40620-021-01231-7
EID:

2-s2.0-85123471742

Part of ISSN: 17246059 11218428
Contributors: Bellini, M.I.; Nozdrin, M.; Pengel, L.; Knight, S.; Papalois, V.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Is Preemptive Kidney Transplantation Associated With Improved Outcomes when Compared to Non-preemptive Kidney Transplantation in Children? A Systematic Review and Meta-Analysis

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10315
EID:

2-s2.0-85127421870

Part of ISSN: 14322277 09340874
Contributors: Rana Magar, R.; Knight, S.; Stojanovic, J.; Marks, S.D.; Lafranca, J.A.; Turner, S.; Dor, F.J.M.F.; Pengel, L.H.M.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Risks for donors associated with living kidney donation: meta-analysis

British Journal of Surgery
2022 | Journal article
DOI: 10.1093/bjs/znac114
EID:

2-s2.0-85134721118

Part of ISSN: 13652168 00071323
Contributors: Bellini, M.I.; Nozdrin, M.; Pengel, L.; Knight, S.; Papalois, V.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10307
EID:

2-s2.0-85127388079

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10706
EID:

2-s2.0-85135995174

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10580
EID:

2-s2.0-85132295162

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10970
EID:

2-s2.0-85144027390

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10434
EID:

2-s2.0-85129386489

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Transplant Trial Watch

Transplant International
2022 | Journal article
DOI: 10.3389/ti.2022.10838
EID:

2-s2.0-85139987220

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation’s Transplant Learning Journey

Transplant International
2021 | Journal article
DOI: 10.1111/tri.13951
EID:

2-s2.0-85117314167

Part of ISSN: 14322277 09340874
Contributors: Jochmans, I.; Hessheimer, A.J.; Neyrinck, A.P.; Paredes, D.; Bellini, M.I.; Dark, J.H.; Kimenai, H.J.A.N.; Pengel, L.H.M.; Watson, C.J.E.; Abelli, M. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Oxygenated End-Hypothermic Machine Perfusion in Expanded Criteria Donor Kidney Transplant: A Randomized Clinical Trial

JAMA Surgery
2021 | Journal article
DOI: 10.1001/jamasurg.2021.0949
EID:

2-s2.0-85105175006

Part of ISSN: 21686262 21686254
Contributors: Husen, P.; Boffa, C.; Jochmans, I.; Krikke, C.; Davies, L.; Mazilescu, L.; Brat, A.; Knight, S.; Wettstein, D.; Cseprekal, O. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

The Educational Value and Emotional Impact on Medical Students After Participating in Transplant Organ Retrieval

Progress in Transplantation
2021 | Journal article
DOI: 10.1177/1526924820978590
EID:

2-s2.0-85097147785

Part of ISSN: 21646708 15269248
Contributors: Reed, A.J.M.; Baldwin-Smith, R.; Arwyn-Jones, J.; Knight, S.; Quiroga, I.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

The impact of recipient demographics on outcomes from living donor kidneys: Systematic review and meta-analysis<sup>†</sup>

Journal of Clinical Medicine
2021 | Journal article
DOI: 10.3390/jcm10235556
EID:

2-s2.0-85119930276

Part of ISSN: 20770383
Contributors: Bellini, M.I.; Nozdrin, M.; Pengel, L.; Knight, S.; Papalois, V.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

The Value of Systematic Reviews and Meta-Analyses in Surgery

European Surgical Research
2021 | Journal article
DOI: 10.1159/000519593
Contributors: Simon R. Knight
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Transplant Trial Watch

Transplant International
2021 | Journal article
DOI: 10.1111/tri.14112
EID:

2-s2.0-85116443500

Part of ISSN: 14322277 09340874
Contributors: Knight, S.R.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Zero tolerance to sexual harassment in surgical training in the UK

British Journal of Surgery
2021 | Journal article
DOI: 10.1093/bjs/znab276
EID:

2-s2.0-85120834019

Part of ISSN: 13652168 00071323
Contributors: Boffa, C.; Ceresa, C.D.L.; Vig, S.; Knight, S.R.; Royston, E.; Quiroga, I.; Sinha, S.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

A systematic review and meta‐analyses of regional perfusion in donation after circulatory death solid organ transplantation

Transplant International
2021-11-19 | Journal article
DOI: 10.1111/tri.14121
Contributors: Julie De Beule; Katrien Vandendriessche; Liset H. M. Pengel; Maria Irene Bellini; John H. Dark; Amelia J. Hessheimer; Hendrikus J. A. N. Kimenai; Simon R. Knight; Arne P. Neyrinck; David Paredes et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Transplant Trial Watch

Transplant International
2021-09 | Journal article
DOI: 10.1111/tri.13977
Contributors: Simon R. Knight; Reshma Rana Magar; Liset Pengel
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Transplant Trial Watch

Transplant International
2021-07-26 | Journal article
DOI: 10.1111/tri.13928
Contributors: Simon R. Knight; Reshma Rana Magar; Liset H. M. Pengel
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Transplant Trial Watch

Transplant International
2021-05 | Journal article
DOI: 10.1111/tri.13871
Contributors: Simon R. Knight; Liset Pengel
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial

The Lancet
2020 | Journal article
DOI: 10.1016/S0140-6736(20)32411-9
EID:

2-s2.0-85096484532

Part of ISSN: 1474547X 01406736
Contributors: Jochmans, I.; Brat, A.; Davies, L.; Hofker, H.S.; van de Leemkolk, F.E.M.; Leuvenink, H.G.D.; Knight, S.R.; Pirenne, J.; Ploeg, R.J.; Abramowicz, D. et al.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier

Pancreas transplantation

Surgery (United Kingdom)
2020 | Journal article
DOI: 10.1016/j.mpsur.2020.04.007
EID:

2-s2.0-85086662539

Part of ISSN: 18781764 02639319
Contributors: Knight, S.; Vogel, T.; Friend, P.
Source: Self-asserted source
Simon R Knight via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (12 reviews for 6 publications/grants)

Review activity for BMJ open. (4)
Review activity for British journal of anaesthesia. (2)
Review activity for Drugs (1)
Review activity for Nature reviews. (1)
Review activity for PloS one. (3)
Review activity for Transplant immunology. (1)
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