Personal information

Other IDs

Scopus Author ID: 57189046506
ResearcherID: I-2071-2019
Scopus Author ID: 56678462800

Keywords

Biochemistry; Toxicology; Pharmacology; Cancer Biology & Therapeutics

Countries

India

Biography

As a biochemist, my research interests span around toxicological and pharmacological studies in animal models with a therapeutic regime and a special emphasis on cellular mechanisms behind cancer biology, touching on broad approaches ranging from early molecular events in carcinogenesis to the rapidly evolving domain of translational research.

Activities

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Employment (3)

Medical College of Wisconsin: Milwaukee, US

2023-08-01 to present | Postdoctoral Researcher (Pharmacology & Toxicology)
Employment
Source: Self-asserted source
Naveenkumar Chandrashekar

Medical College of Wisconsin: Milwaukee, US

2015-11-09 to 2016-06-10 | Postdoctoral Fellow (Pharmacology & Toxicology)
Employment
Source: Self-asserted source
Naveenkumar Chandrashekar

Lund University: Lund, SE

2012-08-01 to 2014-08-01 | Postdoctoral Fellow (Division of Cell & Experimental Pathology, Department of Laboratory Medicine)
Employment
Source: Self-asserted source
Naveenkumar Chandrashekar

Education and qualifications (2)

University of Madras: Chennai, IN

2008-10-23 to 2012-06-11 | PhD (Biochemistry)
Education
Source: Self-asserted source
Naveenkumar Chandrashekar

University of Mysore: Mysore, IN

2005-08-01 to 2007-05-01 | MSc (Biochemistry)
Education
Source: Self-asserted source
Naveenkumar Chandrashekar

Works (28)

Phospholipases: Insights into the potential role of cell death

Phospholipases in Physiology and Pathology
2023 | Book chapter | Author
DOI: 10.1016/b978-0-323-95698-7.00016-4
Part of ISBN: 9780323956871
Contributors: Naveenkumar Chandrashekar; ANANDAKUMAR PANDI
Source: Self-asserted source
Naveenkumar Chandrashekar

The emerging role of phospholipase D in cancer progression and therapeutics

Phospholipases in Physiology and Pathology
2023 | Book chapter | Author
DOI: 10.1016/b978-0-323-95697-0.00019-4
Part of ISBN: 9780323956871
Contributors: Naveenkumar Chandrashekar; ANANDAKUMAR PANDI
Source: Self-asserted source
Naveenkumar Chandrashekar

Benzo(a)Pyrene-Induced Oxidative Stress During Lung Cancer and Treatment with Baicalein

Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
2022 | Book chapter
DOI: 10.1007/978-981-15-9411-3_183
Part of ISBN: 9789811594106
Part of ISBN: 9789811594113
Contributors: Naveenkumar Chandrashekar
Source: Self-asserted source
Naveenkumar Chandrashekar

Cardioprotective effects of Ferulic acid against various drugs and toxic agents

Beni-Suef University Journal of Basic and Applied Sciences
2022-12 | Journal article
DOI: 10.1186/s43088-022-00273-5
Part of ISSN: 2314-8543
Contributors: Naveenkumar Chandrashekar
Source: Self-asserted source
Naveenkumar Chandrashekar

Effects of d-pinitol on diabetes mellitus: an updated review

Bulletin of the National Research Centre
2022-12 | Journal article
DOI: 10.1186/s42269-022-00820-1
Part of ISSN: 2522-8307
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Baicalein: A review on its anti‐cancer effects and mechanisms in lung carcinoma

Journal of Food Biochemistry
2022-05-11 | Journal article
DOI: 10.1111/jfbc.14230
Part of ISSN: 0145-8884
Part of ISSN: 1745-4514
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo(a)pyrene‐induced pulmonary carcinogenesis in mice

Journal of Biochemical and Molecular Toxicology
2022-03-25 | Journal article
DOI: 10.1002/jbt.23053
Part of ISSN: 1095-6670
Part of ISSN: 1099-0461
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Benzo(a)pyrene-Induced Oxidative Stress During Lung Cancer and Treatment with Baicalein

Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
2021 | Journal article
DOI: 10.1007/978-981-15-4501-6_183-1
Contributors: Naveenkumar Chandrashekar
Source: check_circle
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Cerium oxide nanoparticles induced physio-biochemical, neurochemical, and morphological responses in Cirrhinus mrigala during short term exposure

Asia-Pacific Journal of Molecular Biology and Biotechnology
2021 | Journal article
DOI: 10.35118/APJMBB.2021.029.2.06
Contributors: Kalpesh Swamy; Naveenkumar Chandrashekar; Raghunandhakumar Subramanian; Sandya Sukumaran; Sharath Chandra
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Physio-biochemical responses of indian major carp catla catla upon sub-chronic exposure to tin oxide nanoparticles

Egyptian Journal of Aquatic Biology and Fisheries
2020 | Journal article
DOI: 10.21608/EJABF.2020.102144
EID:

2-s2.0-85089401694

Part of ISSN: 25369814 11106131
Contributors: Perva, S.; Swamy, K.; Chandrashekar, N.; Subramanian, R.; Sukumaran, S.; Sharath, C.S.P.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier

Montelukast, a CysLT1 receptor antagonist, reduces colon cancer stemness and tumor burden in a mouse xenograft model of human colon cancer

Cancer Letters
2018 | Journal article
DOI: 10.1016/j.canlet.2018.08.019
EID:

2-s2.0-85052505972

Part of ISSN: 18727980 03043835
Contributors: Bellamkonda, K.; Satapathy, S.R.; Douglas, D.; Chandrashekar, N.; Selvanesan, B.C.; Liu, M.; Savari, S.; Jonsson, G.; Sjölander, A.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier
grade
Preferred source (of 2)‎

Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer

Oncotarget
2017 | Journal article
DOI: 10.18632/oncotarget.16718
EID:

2-s2.0-85019888210

Part of ISSN: 19492553
Contributors: Osman, J.; Savari, S.; Chandrashekar, N.K.; Bellamkonda, K.; Douglas, D.; Sjölander, A.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier
grade
Preferred source (of 2)‎

Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the Apc<sup>Min/+</sup> mouse model

Carcinogenesis
2016 | Journal article
DOI: 10.1093/carcin/bgw031
EID:

2-s2.0-84964884533

Part of ISSN: 14602180 01433334
Contributors: Savari, S.; Chandrashekar, N.K.; Osman, J.; Douglas, D.; Bellamkonda, K.; Jönsson, G.; Juhas, M.; Greicius, G.; Pettersson, S.; Sjölander, A.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier
grade
Preferred source (of 2)‎

The eicosanoids leukotriene D<inf>4</inf> and prostaglandin E<inf>2</inf> promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model

BMC Cancer
2016 | Journal article
DOI: 10.1186/s12885-016-2466-z
EID:

2-s2.0-84978811128

Part of ISSN: 14712407
Contributors: Bellamkonda, K.; Chandrashekar, N.K.; Osman, J.; Selvanesan, B.C.; Savari, S.; Sjölander, A.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Anticancer Role of Capsaicin in Experimentallyinduced Lung Carcinogenesis.

Journal of pharmacopuncture
2015-06 | Journal article
DOI: 10.3831/kpi.2015.18.011
PMID: 26120484
PMC: PMC4481395
Contributors: Anandakumar P; Kamaraj S; Jagan S; Ramakrishnan G; Asokkumar S; Naveenkumar C; Raghunandhakumar S; Vanitha MK; Devaki T
Source: Self-asserted source
Naveenkumar Chandrashekar via Europe PubMed Central
grade
Preferred source (of 2)‎

Identifying genes involved in the colon cancer initiating cells (CICs) survivability against montelukast treatment in xenograft model

European Journal of Cancer
2014 | Journal article
DOI: 10.1016/S0959-8049(14)50799-X
WOSUID: WOS:000351589702082
Contributors: Bellamkonda, K.; Savari, S.; Chandrashekar, N.; Sjolander, A.
Source: check_circle
Web of Science Researcher Profile Sync

Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma

Toxicology Letters
2013-10 | Journal article
DOI: 10.1016/j.toxlet.2013.08.018
Part of ISSN: 0378-4274
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene.

Fundamental & clinical pharmacology
2013-07 | Journal article
DOI: 10.1111/fcp.12036
PMID: 23834621
Contributors: Naveenkumar C; Raghunandakumar S; Asokkumar S; Binuclara J; Rajan B; Premkumar T; Devaki T
Source: Self-asserted source
Naveenkumar Chandrashekar via Europe PubMed Central
grade
Preferred source (of 2)‎

Anti-fibrotic effect of diosmin against dmn-induced liver fibrosis in rats: a biochemical analysis.

International Journal of Research in Pharmaceutical and Nano Sciences.
2013-06 | Journal article
Source: Self-asserted source
Naveenkumar Chandrashekar

Abstract 2721: Growth of HCT-116 colon cancer xenografts is inhibited by CysLT1R antagonists.

Cancer Research
2013-04-15 | Journal article
DOI: 10.1158/1538-7445.am2013-2721
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Anita Sjölander; Sayeh Savari; Yuan Zhang; Wondossen Sime; Naveen Kumar Chandrashekar; Minghui Liu
Source: Self-asserted source
Naveenkumar Chandrashekar

Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo

Toxicology and Applied Pharmacology
2012 | Journal article
DOI: 10.1016/j.taap.2012.02.004
EID:

2-s2.0-84860518210

Part of ISSN: 0041008X 10960333
Contributors: Chandrashekar, N.; Selvamani, A.; Subramanian, R.; Pandi, A.; Thiruvengadam, D.
Source: Self-asserted source
Naveenkumar Chandrashekar via Scopus - Elsevier
grade
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Baicalein abrogates reactive oxygen species (ROS)-mediated mitochondrial dysfunction during experimental pulmonary carcinogenesis in vivo.

Basic & clinical pharmacology & toxicology
2012-12 | Journal article
DOI: 10.1111/bcpt.12025
PMID: 23061789
Contributors: Naveenkumar C; Raghunandhakumar S; Asokkumar S; Devaki T
Source: Self-asserted source
Naveenkumar Chandrashekar via Europe PubMed Central
grade
Preferred source (of 2)‎

Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model

Inflammation Research
2012-11 | Journal article
DOI: 10.1007/s00011-012-0511-1
Part of ISSN: 1023-3830
Part of ISSN: 1420-908X
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Baicalein improves antioxidant status and membrane-bound enzymes during oxidative stress in benzo(a)pyrene-induced lung carcinogenesis in mice

Biomedicine & Preventive Nutrition
2012-04 | Journal article
DOI: 10.1016/j.bionut.2011.12.004
Part of ISSN: 2210-5239
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.

Molecular and cellular biochemistry
2011-12 | Journal article
DOI: 10.1007/s11010-011-1186-6
PMID: 22187222
Contributors: Asokkumar S; Naveenkumar C; Raghunandhakumar S; Kamaraj S; Anandakumar P; Jagan S; Devaki T
Source: Self-asserted source
Naveenkumar Chandrashekar via Europe PubMed Central
grade
Preferred source (of 2)‎

Chemopreventive potential of Geraniol on 4-Nitroquinoline-1-oxide induced oral carcinogenesis in rats.

International Journal of Research in Pharmaceutical Sciences.
2011-10 | Journal article
Source: Self-asserted source
Naveenkumar Chandrashekar

Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis.

Fundamental & clinical pharmacology
2011-02 | Journal article
DOI: 10.1111/j.1472-8206.2010.00910.x
PMID: 21323996
Contributors: Naveenkumar C; Asokkumar S; Raghunandhakumar S; Jagan S; Anandakumar P; Augustine TA; Kamaraj S; Devaki T
Source: Self-asserted source
Naveenkumar Chandrashekar via Europe PubMed Central
grade
Preferred source (of 2)‎

Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis

Molecular and Cellular Biochemistry
2009-11 | Journal article
DOI: 10.1007/s11010-009-0151-0
Part of ISSN: 0300-8177
Part of ISSN: 1573-4919
Source: Self-asserted source
Naveenkumar Chandrashekar
grade
Preferred source (of 2)‎

Peer review (16 reviews for 9 publications/grants)

Review activity for American journal of molecular biology. (1)
Review activity for BMC complementary and alternative medicine (6)
Review activity for Cancer medicine. (2)
Review activity for Current bioactive compounds. (1)
Review activity for Journal of biosciences and medicines (1)
Review activity for PloS one. (1)
Review activity for Process biochemistry. (1)
Review activity for Scientific reports. (1)
Review activity for Toxicology mechanisms and methods. (2)
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