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Works (45)

Acetylcholinesterase as a Target for Heliotridine-Type Alkaloids Isolated from Plants: A Computational Study

2024-11-14 | Conference paper
Contributors: Andrea Defant; Thamere Cheriet; Ines Mancini
Source: check_circle
Crossref

3a-(4-Chlorophenyl)-1-thioxo-2,3,3a,4-tetrahydroimidazo[1,5-a]quinazolin-5(1H)-one

Molbank
2024-07-28 | Journal article
Contributors: Andrea Defant; Nicole Innocenti; Ines Mancini
Source: check_circle
Crossref
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EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness

International Journal of Molecular Sciences
2024-04 | Journal article | Author
Contributors: Simona Cocchi; Valentina Greco; Viktoryia Sidarovich; Jacopo Vigna; Francesca Broso; Diana Corallo; Jacopo Zasso; Angela Re; Emanuele Filiberto Rosatti; Sara Longhi et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Structural Insights into the Marine Alkaloid Discorhabdin G as a Scaffold towards New Acetylcholinesterase Inhibitors

Marine Drugs
2024-04-12 | Journal article
Contributors: Andrea Defant; Giacomo Carloni; Nicole Innocenti; Tomaž Trobec; Robert Frangež; Kristina Sepčić; Ines Mancini
Source: check_circle
Crossref
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3a-(4-Chlorophenyl)-1-methyl-3a,4-dihydroimidazo[1,5-a]quinazolin-5(3H)-one: Synthesis and In Silico Evaluation as a Ligand in the µ-Opioid Receptor

MolBank
2023 | Journal article
EID:

2-s2.0-85163710388

Part of ISSN: 14228599
Contributors: Defant, A.; Innocenti, N.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth

Marine Drugs
2023 | Journal article
EID:

2-s2.0-85151168423

Part of ISSN: 16603397
Contributors: Vigna, J.; Sighel, D.; Rosatti, E.F.; Defant, A.; Pancher, M.; Sidarovich, V.; Quattrone, A.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

A Comprehensive Computational NMR Analysis of Organic Polyarsenicals including the Marine Sponge-Derived Arsenicins A–D and Their Synthetic Analogs

Marine Drugs
2023-09 | Journal article | Author
Contributors: Andrea Defant; Ines Mancini
Source: check_circle
Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents

Molecules
2022 | Journal article
EID:

2-s2.0-85136343201

Part of ISSN: 14203049
Contributors: Mancini, I.; Vigna, J.; Sighel, D.; Defant, A.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis of Nucleoside-like Molecules from a Pyrolysis Product of Cellulose and Their Computational Prediction as Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors

International Journal of Molecular Sciences
2022 | Journal article
EID:

2-s2.0-85122084811

Part of ISSN: 14220067 16616596
Contributors: Defant, A.; Dosi, F.; Innocenti, N.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Lc-esi/ms-phytochemical profiling with antioxidant, antibacterial, antifungal, antiviral and in silico pharmacological properties of algerian asphodelus tenuifolius (Cav.) organic extracts

Antioxidants
2021 | Journal article
EID:

2-s2.0-85104415595

Part of ISSN: 20763921
Contributors: Khalfaoui, A.; Noumi, E.; Belaabed, S.; Aouadi, K.; Lamjed, B.; Adnan, M.; Defant, A.; Kadri, A.; Snoussi, M.; Khan, M.A. et al.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Structural isomerism and enhanced lipophilicity of pyrithione ligands of organoruthenium(Ii) complexes increase inhibition on ache and buche

International Journal of Molecular Sciences
2020 | Journal article
EID:

2-s2.0-85089359952

Part of ISSN: 14220067 16616596
Contributors: Kladnik, J.; Ristovski, S.; Kljun, J.; Defant, A.; Mancini, I.; Sepčić, K.; Turel, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Actinobacteria derived from algerian ecosystems as a prominent source of antimicrobial molecules

Antibiotics
2019 | Journal article
EID:

2-s2.0-85076508572

Part of ISSN: 20796382
Contributors: Djinni, I.; Defant, A.; Kecha, M.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Design, synthesis and cancer cell growth inhibition evaluation of new aminoquinone hybrid molecules

Molecules
2019 | Journal article
EID:

2-s2.0-85067307328

Part of ISSN: 14203049
Contributors: Defant, A.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Enhanced production and quantitative evaluation of nigericin from the Algerian soil-living streptomyces youssoufiensis SF10 strain

Fermentation
2019 | Journal article
EID:

2-s2.0-85063139884

Part of ISSN: 23115637
Contributors: Leulmi, N.; Sighel, D.; Defant, A.; Khenaka, K.; Boulahrouf, A.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Modeling improved production of the chemotherapeutic polypeptide actinomycin D by a novel Streptomyces sp. strain from a Saharan soil

Heliyon
2019 | Journal article
EID:

2-s2.0-85066147350

Part of ISSN: 24058440
Contributors: Djinni, I.; Defant, A.; Djoudi, W.; Chaabane Chaouch, F.; Souagui, S.; Kecha, M.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Nigericin and grisorixin methyl ester from the Algerian soil-living Streptomyces youssoufiensis SF10 strain: a computational study on their epimeric structures and evaluation of glioblastoma stem cells growth inhibition

Natural Product Research
2019 | Journal article
EID:

2-s2.0-85043316015

Part of ISSN: 14786427 14786419
Contributors: Leulmi, N.; Sighel, D.; Defant, A.; Khenaka, K.; Boulahrouf, A.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis of 2,6-diamino-substituted purine derivatives and evaluation of cell cycle arrest in breast and colorectal cancer cells

Molecules
2018 | Journal article
EID:

2-s2.0-85053635019

Part of ISSN: 14203049
Contributors: Bosco, B.; Defant, A.; Messina, A.; Incitti, T.; Sighel, D.; Bozza, A.; Ciribilli, Y.; Inga, A.; Casarosa, S.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

European Journal of Medicinal Chemistry
2017 | Journal article
EID:

2-s2.0-85018920580

Part of ISSN: 17683254 02235234
Contributors: Botić, T.; Defant, A.; Zanini, P.; Žužek, M.C.; Frangež, R.; Janussen, D.; Kersken, D.; Knez, Ž.; Mancini, I.; Sepčić, K.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Microwave-assisted synthesis of new imide- And formamide-derivatives of 2(3H)-benzoxazolinones and 2(3H)-benzothiazolinones

Arkivoc
2017 | Journal article
EID:

2-s2.0-85117795314

Part of ISSN: 15517012 15517004
Contributors: Seddiki, K.; Yahia, W.; Liacha, M.; Defant, A.; Sighel, D.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Microwave-assisted synthesis of new imide-and formamide-derivatives of 2(3H)-benzoxazolinones and 2(3H)-benzothiazolinones

Arkivoc
2017 | Journal article
EID:

2-s2.0-85020749505

Part of ISSN: 15517012 15517004
Contributors: Seddiki, K.; Yahia, W.; Liacha, M.; Defant, A.; Sighel, D.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis and in-vitro anticancer evaluation of polyarsenicals related to the marine sponge derived Arsenicin A

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85029484329

Part of ISSN: 20452322
Contributors: Mancini, I.; Planchestainer, M.; Defant, A.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Design, synthesis, and biological evaluation of novel 2H-pyran-2-one derivatives as potential HIV-1 reverse transcriptase inhibitors

Archiv der Pharmazie
2015 | Journal article
EID:

2-s2.0-84920718056

Part of ISSN: 15214184 03656233
Contributors: Defant, A.; Mancini, I.; Tomazzolli, R.; Balzarini, J.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Muscarine-like compounds derived from a pyrolysis product of cellulose

Organic and Biomolecular Chemistry
2015 | Journal article
EID:

2-s2.0-84930629699

Part of ISSN: 14770520
Contributors: Defant, A.; Mancini, I.; Matucci, R.; Bellucci, C.; Dosi, F.; Malferrari, D.; Fabbri, D.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Chemical constituents of Linaria reflexa Desf.(Scrophulariaceae)

Der Pharmacia Lettre
2014 | Journal article
EID:

2-s2.0-84903368415

Part of ISSN: 09755071
Contributors: Cheriet, T.; Aouabdia, S.; Mancini, I.; Defant, A.; Seghiri, R.; Boumaza, O.; Mekkiou, R.; Sarri, D.; León, F.; Brouard, I. et al.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Metabolite profile of marine-derived endophytic Streptomyces sundarbansensis WR1L1S8 by liquid chromatography-mass spectrometry and evaluation of culture conditions on antibacterial activity and mycelial growth

Journal of Applied Microbiology
2014 | Journal article
EID:

2-s2.0-84890433183

Part of ISSN: 13652672 13645072
Contributors: Djinni, I.; Defant, A.; Kecha, M.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Upgraded production of (1R,5S)-1-hydroxy-3,6-dioxa-bicyclo[3.2.1] octan-2-one from cellulose catalytic pyrolysis and its detection in bio-oils by spectroscopic methods

Journal of Analytical and Applied Pyrolysis
2014 | Journal article
EID:

2-s2.0-84922744964

Part of ISSN: 01652370
Contributors: Mancini, I.; Dosi, F.; Defant, A.; Crea, F.; Miotello, A.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

A study on the regioselectivity in N,C-acylation of β-enamino-esters

Tetrahedron
2013 | Journal article
EID:

2-s2.0-84877005548

Part of ISSN: 00404020 14645416
Contributors: Defant, A.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Antibacterial polyketides from the marine alga-derived endophitic streptomyces sundarbansensis: A study on hydroxypyrone tautomerism

Marine Drugs
2013 | Journal article
EID:

2-s2.0-84873150907

Part of ISSN: 16603397
Contributors: Djinni, I.; Defant, A.; Kecha, M.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Bioactive poly(arsenic) compounds

Progress in molecular and subcellular biology
2013 | Journal article
EID:

2-s2.0-84948147505

Part of ISSN: 00796484
Contributors: Mancini, I.; Defant, A.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

A joint experimental and theoretical investigation on the oxidative coupling of resveratrol induced by copper and iron ions

International Journal of Mass Spectrometry
2012 | Journal article
EID:

2-s2.0-84863721138

Part of ISSN: 13873806
Contributors: Tamboli, V.F.; Re, N.; Coletti, C.; Defant, A.; Mancini, I.; Tosi, P.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Aggregation processes in micellar solutions: A Raman study

Journal of Raman Spectroscopy
2012 | Journal article
EID:

2-s2.0-84871243520

Part of ISSN: 10974555 03770486
Contributors: Cazzolli, G.; Caponi, S.; Defant, A.; Gambi, C.M.C.; Marchetti, S.; Mattarelli, M.; Montagna, M.; Rossi, B.; Rossi, F.; Viliani, G.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Antifungal and antibacterial activity of 3-alkylpyridinium polymeric analogs of marine toxins

International Biodeterioration and Biodegradation
2012 | Journal article
EID:

2-s2.0-84856078058

Part of ISSN: 09648305
Contributors: Zovko, A.; Vaukner Gabrič, M.; Sepčić, K.; Pohleven, F.; Jaklič, D.; Gunde-Cimerman, N.; Lu, Z.; Edrada-Ebel, R.; Houssen, W.E.; Mancini, I. et al.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Positron scattering from chiral enantiomers

Physical Review A - Atomic, Molecular, and Optical Physics
2012 | Journal article
EID:

2-s2.0-84861644131

Part of ISSN: 10502947 10941622
Contributors: Chiari, L.; Zecca, A.; Girardi, S.; Defant, A.; Wang, F.; Ma, X.G.; Perkins, M.V.; Brunger, M.J.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

A study of resveratrol-copper complexes by electrospray ionization mass spectrometry and density functional theory calculations

Rapid Communications in Mass Spectrometry
2011 | Journal article
EID:

2-s2.0-79251500007

Part of ISSN: 10970231 09514198
Contributors: Tamboli, V.; Defant, A.; Mancini, I.; Tosi, P.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

An efficient route towards a new branched tetrahydrofurane δ-sugar amino acid from a pyrolysis product of cellulose

Amino Acids
2011 | Journal article
EID:

2-s2.0-78751572959

Part of ISSN: 09394451
Contributors: Defant, A.; Mancini, I.; Torri, C.; Malferrari, D.; Fabbri, D.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Fatty acid composition of common barbel (Barbus barbus) roe and evaluation of its haemolytic and cytotoxic activities

Toxicon
2011 | Journal article
EID:

2-s2.0-79956358041

Part of ISSN: 00410101 18793150
Contributors: Mancini, I.; Defant, A.; Mesarič, T.; Potočnik, F.; Batista, U.; Guella, G.; Turk, T.; Sepčić, K.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

New structural insights into saraines A, B, and C, macrocyclic alkaloids from the mediterranean sponge Reniera (Haliclona) sarai

European Journal of Organic Chemistry
2011 | Journal article
EID:

2-s2.0-79960317854

Part of ISSN: 1434193X 10990690
Contributors: Defant, A.; Mancini, I.; Raspor, L.; Guella, G.; Turk, T.; Sepčić, K.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Metal-assisted regioselectivity in nucleophilic substitutions: A study byRaman spectroscopy and density functional theory calculations

Journal of Raman Spectroscopy
2010 | Journal article
EID:

2-s2.0-79952172944

Part of ISSN: 10974555 03770486
Contributors: Defant, A.; Rossi, B.; Viliani, G.; Guella, G.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis and in-vitro cytotoxicity evaluation of novel naphtindolizinedione derivatives, part II: Improved activity for aza-analogues

Archiv der Pharmazie
2009 | Journal article
EID:

2-s2.0-62549125458

Part of ISSN: 15214184 03656233
Contributors: Defant, A.; Guella, G.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Microwave-assisted multicomponent synthesis of aza-, diaza-, benzo-, and dibenzofluorenedione derivatives

Synthetic Communications
2008 | Journal article
EID:

2-s2.0-50649084307

Part of ISSN: 00397911 15322432
Contributors: Defant, A.; Guella, G.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis of marine natural products with antimalarial activity

Mini-Reviews in Medicinal Chemistry
2008 | Journal article
EID:

2-s2.0-57149132404

Part of ISSN: 13895575
Contributors: Mancini, I.; Guella, G.; Defant, A.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Recent synthesis of marine natural products with antibacterial activities

Anti-Infective Agents in Medicinal Chemistry
2007 | Journal article
EID:

2-s2.0-33846112194

Part of ISSN: 18715214
Contributors: Mancini, I.; Defant, A.; Guella, G.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Synthesis and in vitro cytotoxicity evaluation of novel naphthindolizinedione derivatives

Archiv der Pharmazie
2007 | Journal article
EID:

2-s2.0-34250352377

Part of ISSN: 03656233 15214184
Contributors: Defant, A.; Guella, G.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Regioselectivity in the multi-component synthesis of indolizinoquinoline-5, 12-dione derivatives

European Journal of Organic Chemistry
2006 | Journal article
EID:

2-s2.0-33748771505

Part of ISSN: 1434193X 10990690
Contributors: Defant, A.; Guella, G.; Mancini, I.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier

Polar Metabolites of the Tropical Green Seaweed Caulerpa taxifolia Which Is Spreading in the Mediterranean Sea: Glycoglycerolipids and Stable Enols (α-Keto Esters)

Helvetica Chimica Acta
1998 | Journal article
EID:

2-s2.0-0008935105

Part of ISSN: 0018019X
Contributors: Mancini, I.; Guella, G.; Defant, A.; Luz Candenas, M.; Armesto, C.P.; Depentori, D.; Pietra, F.
Source: Self-asserted source
Andrea Defant via Scopus - Elsevier