Personal information

Biography

I commenced PhD research in the Zoonotic Animal Pathogen Research Laboratory, The Roslin institute, University of Edinburgh. After my PhD I worked as a Post-Doctoral Scientist at the University of Edinburgh on a vaccine research project in collaboration with the University of Glasgow. I have a good track record of publishing my research in leading subject journals including Cell host and Microbe, Infection and Immunity, Molecular Microbiology, Veterinary Research and Antimicrobial Agent and Chemotherapy. Over 7 year at Edinburgh University I gained expertise in cellular and molecular techniques. These include expertise in cell and tissue culture, bacterial molecular genetics, confocal microscopy and signaling pathway analysis that gave me a unique strength to achieve two excellent papers as part of my PhD research, including one in Infection and Immunity (Tahoun et al., 2011) that help understanding the cellular and molecular basis of E. coli O157:H7 interaction with Macrophage and Human and ruminant M cell. The other work was published in Cell Host & Microbe (Tahoun et al., 2012), that discovered a new mechanism by which Salmonella can transform specific epithelial cells to drive its own uptake. Since my PhD I have been employed on a 3-year research grant investigating both the adjuvancy of H7 flagella and enhancing the development of a vaccine for use in cattle aimed at limiting the excretion of enterohaemorrhagic Escherichia coli. This has included research proving the functionality of bovine TLR5 that have been published in Veterinary research (Tahoun et al., 2015), and more recent research on presentation of heterologous antigens and host specific recognition and signaling by TLR5. This work completed but still on writing it up. The work with human TLR5 also helped me to be leading to co-authorship of a manuscript in Molecular Microbiology (Beckham et al., 2014) I also studied the Inhibition of type III secretion expression in EHEC by sub-inhibitory concentrations of ketolides as a joint first author that published in antimicrobial agent and chemotherapy this work will help in treatment of human from such serious disease.  I have presented and will be presenting my research at national and international conferences to disseminate my research to wider research community. I aim to continue to publish in these scientific journals to share my research on this important organisms interaction with eukaryotic cells with other fellow researchers in the field.

Activities

Works (26)

Epidemiological, and molecular investigation of Canine parvovirus-2 infection in Egypt

Journal of Veterinary Science
2024 | Journal article
Contributors: Eman Farag Ammar; Yamen Mohammed Hegazy; Magdy Al-gaabary; Samah M. Mosad; Mohamed Salem; Mohamed Marzok; Fadhel Housawi; Mohamed Al-ali; Abdulrahman Alhaider; Amin Tahoun
Source: check_circle
Crossref

Pathology and Epidemiology of Fungal Infections in Layer Chicken Flocks

Advanced Gut & Microbiome Research
2023-04-24 | Journal article
Contributors: Hanem El-Sharkawy; Ahmed M. Abd El-Salam; Amin Tahoun; Jiong Yu
Source: check_circle
Crossref

Overview on Cryptosporidium bovis and Its Effect on Calves in Some Governorates in Egypt

Journal of Tropical Medicine
2022 | Journal article
EID:

2-s2.0-85132029097

Part of ISSN: 16879694 16879686
Contributors: Abdelaziz, A.R.; Tahoun, A.; El-Sharkawy, H.; Abd El-Salam, M.M.; Alorabi, M.; El-Shehawi, A.M.; El Meghanawy, R.A.; Toukhy, E.E.; Abd El-Salam, A.M.; Sorour, S.S.G.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Prevalence and Molecular Biology of Staphylococcus aureus Isolated from Healthy and Diseased Equine Eyes in Egypt

Antibiotics
2022 | Journal article
EID:

2-s2.0-85125571741

Part of ISSN: 20796382
Contributors: Tahoun, A.; Elnafarawy, H.K.; El-Sharkawy, H.; Rizk, A.M.; Alorabi, M.; El-Shehawi, A.M.; Youssef, M.A.; Ibrahim, H.M.M.; El-Khodery, S.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Epidemiological, Morphological, and Morphometric Study on Haemonchus spp. Recovered From Goats in Egypt

Frontiers in Veterinary Science
2021 | Journal article
EID:

2-s2.0-85118769201

Part of ISSN: 22971769
Contributors: Gareh, A.; Elhawary, N.M.; Tahoun, A.; Ramez, A.M.; EL-shewehy, D.M.M.; Elbaz, E.; Khalifa, M.I.; Alsharif, K.F.; Khalifa, R.M.A.; Dyab, A.K. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Epidemiological, Morphometric, and Molecular Investigation of Cystic Echinococcosis in Camel and Cattle From Upper Egypt: Current Status and Zoonotic Implications

Frontiers in Veterinary Science
2021 | Journal article
EID:

2-s2.0-85117328624

Part of ISSN: 22971769
Contributors: Gareh, A.; Saleh, A.A.; Moustafa, S.M.; Tahoun, A.; Baty, R.S.; Khalifa, R.M.A.; Dyab, A.K.; Yones, D.A.; Arafa, M.I.; Abdelaziz, A.R. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Mitotic arrest-deficient 2 like 2 (Mad2l2) interacts with escherichia coli effector protein espf

Life
2021 | Journal article
EID:

2-s2.0-85115149904

Part of ISSN: 20751729
Contributors: Tahoun, A.; El-Sharkawy, H.; Moustafa, S.M.; Abdel-Hafez, L.J.M.; Albrakati, A.; Koegl, M.; Haas, J.; Mahajan, A.; Gally, D.L.; Elmahallawy, E.K.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Prevalence, antimicrobial resistance, and genotyping of Shiga toxin-producing Escherichia coli in foods of cattle origin, diarrheic cattle, and diarrheic humans in Egypt

Gut Pathogens
2021 | Journal article
EID:

2-s2.0-85100525337

Part of ISSN: 17574749
Contributors: Elmonir, W.; Shalaan, S.; Tahoun, A.; Mahmoud, S.F.; Remela, E.M.A.; Eissa, R.; El-Sharkawy, H.; Shukry, M.; Zahran, R.N.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Ameliorative effect of heat-killed lactobacillus plantarum L.137 and/or Aloe vera against colitis in mice

Processes
2020 | Journal article
EID:

2-s2.0-85080943414

Part of ISSN: 22279717
Contributors: Ismaeil, H.; Abdo, W.; Amer, S.; Tahoun, A.; Massoud, D.; Zanaty, E.; Bin-Jumah, M.; Mahmoud, A.M.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Bacterial flagella disrupt host cell membranes and interact with cytoskeletal components

bioRxiv
2020 | Other
EID:

2-s2.0-85098910834

Part of ISSN: 26928205
Contributors: Wolfson, E.B.; Elvidge, J.; Tahoun, A.; Gillespie, T.; Mantell, J.; McAteer, S.P.; Rossez, Y.; Paxton, E.; Lane, F.; Shaw, D.J. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Cefotaxime pharmacokinetics in Arabian camel (Camelus dromedarius) calves after single intravenous injection

Tropical Animal Health and Production
2020 | Journal article
EID:

2-s2.0-85074809741

Part of ISSN: 15737438 00494747
Contributors: Altayban, A.; Kandeel, M.; Tahoun, A.; Al-Nazawi, M.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Enhanced antibacterial activity of silver nanoparticles combined with hydrogen peroxide against multidrug-resistant pathogens isolated from dairy farms and beef slaughterhouses in egypt

Infection and Drug Resistance
2020 | Journal article
EID:

2-s2.0-85092404797

Part of ISSN: 11786973
Contributors: El-Gohary, F.A.; Abdel-Hafez, L.J.M.; Zakaria, A.I.; Shata, R.R.; Tahoun, A.; El-Mleeh, A.; Abo Elfadl, E.A.; Elmahallawy, E.K.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Epidemiological and molecular investigation of ocular fungal infection in equine from Egypt

Veterinary Sciences
2020 | Journal article
EID:

2-s2.0-85091700278

Part of ISSN: 23067381
Contributors: Tahoun, A.; Elnafarawy, H.K.; Elmahallawy, E.K.; Abdelhady, A.; Rizk, A.M.; El-Sharkawy, H.; Youssef, M.A.; El-Khodery, S.; Ibrahim, H.M.M.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Evaluation of bifidobacteria and lactobacillus probiotics as alternative therapy for salmonella typhimurium infection in broiler chickens

Animals
2020 | Journal article
EID:

2-s2.0-85088607512

Part of ISSN: 20762615
Contributors: El-Sharkawy, H.; Tahoun, A.; Rizk, A.M.; Suzuki, T.; Elmonir, W.; Nassef, E.; Shukry, M.; Germoush, M.O.; Farrag, F.; Bin-Jumah, M. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Inflammasome activation in bovine peripheral blood-derived macrophages is associated with actin rearrangement

Animals
2020 | Journal article
EID:

2-s2.0-85083714704

Part of ISSN: 20762615
Contributors: Tahoun, A.; Jensen, K.; El-Sharkawy, H.; Gally, D.; Rizk, A.M.; Ajarem, J.; Allam, A.; Mahmoud, A.M.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Molecular characterization and developing a point-of-need molecular test for diagnosis of bovine papillomavirus (Bpv) type 1 in cattle from Egypt

Animals
2020 | Journal article
EID:

2-s2.0-85093921366

Part of ISSN: 20762615
Contributors: El-Tholoth, M.; Mauk, M.G.; Elnaker, Y.F.; Mosad, S.M.; Tahoun, A.; El-Sherif, M.W.; Lokman, M.S.; Kassab, R.B.; Abdelsadik, A.; Saleh, A.A. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

The interaction of escherichia coli O157:H7 and salmonella typhimurium flagella with host cell membranes and cytoskeletal components

Microbiology (United Kingdom)
2020 | Journal article
EID:

2-s2.0-85094983428

Part of ISSN: 14652080 13500872
Contributors: Wolfson, E.B.; Elvidge, J.; Tahoun, A.; Gillespie, T.; Mantell, J.; McAteer, S.P.; Rossez, Y.; Paxton, E.; Lane, F.; Shaw, D.J. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

An RNA-dependent mechanism for transient expression of bacterial translocation filaments

2018-04-20 | Journal article
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Amin Tahoun
grade
Preferred source (of 2)‎

Capsular polysaccharide inhibits adhesion of Bifidobacterium longum 105-A to enterocyte-like Caco-2 cells and phagocytosis by macrophages

Gut Pathogens
2017 | Journal article
EID:

2-s2.0-85018944742

Contributors: Tahoun, A.; Masutani, H.; El-Sharkawy, H.; Gillespie, T.; Honda, R.P.; Kuwata, K.; Inagaki, M.; Yabe, T.; Nomura, I.; Suzuki, T.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Epidemiological, molecular characterization and antibiotic resistance of Salmonella enterica serovars isolated from chicken farms in Egypt

Gut Pathogens
2017 | Journal article
EID:

2-s2.0-85011955282

Contributors: El-Sharkawy, H.; Tahoun, A.; El-Gohary, A.E.-G.A.; El-Abasy, M.; El-Khayat, F.; Gillespie, T.; Kitade, Y.; Hafez, H.M.; Neubauer, H.; El-Adawy, H.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Host species adaptation of TLR5 signalling and flagellin recognition

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85038224656

Contributors: Tahoun, A.; Jensen, K.; Corripio-Miyar, Y.; McAteer, S.; Smith, D.G.E.; McNeilly, T.N.; Gally, D.L.; Glass, E.J.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Type III secretion-dependent sensitivity of Escherichia coli O157 to specific ketolides

Antimicrobial Agents and Chemotherapy
2016 | Journal article
EID:

2-s2.0-84957895293

Contributors: Fernandez-Brando, R.J.; Yamaguchi, N.; Tahoun, A.; McAteer, S.P.; Gillespie, T.; Wang, D.; Argyle, S.A.; Palermo, M.S.; Gally, D.L.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Functional analysis of bovine TLR5 and association with IgA responses of cattle following systemic immunisation with H7 flagella

Veterinary Research
2015 | Journal article
EID:

2-s2.0-84924086689

Contributors: Tahoun, A.; Jensen, K.; Corripio-Miyar, Y.; McAteer, S.P.; Corbishley, A.; Mahajan, A.; Brown, H.; Frew, D.; Aumeunier, A.; Smith, D.G.E. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

The metabolic enzyme AdhE controls the virulence of Escherichia coliO157: H7

Molecular Microbiology
2014 | Journal article
EID:

2-s2.0-84903473850

Contributors: Beckham, K.S.H.; Connolly, J.P.R.; Ritchie, J.M.; Wang, D.; Gawthorne, J.A.; Tahoun, A.; Gally, D.L.; Burgess, K.; Burchmore, R.J.; Smith, B.O. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Salmonella transforms follicle-associated epithelial cells into M cells to promote intestinal invasion

Cell Host and Microbe
2012 | Journal article
EID:

2-s2.0-84869153585

Contributors: Tahoun, A.; Mahajan, S.; Paxton, E.; Malterer, G.; Donaldson, D.S.; Wang, D.; Tan, A.; Gillespie, T.L.; O'Shea, M.; Roe, A.J. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Comparative analysis of EspF variants in inhibition of Escherichia coli phagocytosis by macrophages and inhibition of E. Coli translocation through human- and bovine-derived M cells

Infection and Immunity
2011 | Journal article
EID:

2-s2.0-80855134586

Contributors: Tahoun, A.; Siszler, G.; Spears, K.; McAteer, S.; Tree, J.; Paxton, E.; Gillespie, T.L.; Martinez-Argudo, I.; Jepson, M.A.; Shaw, D.J. et al.
Source: Self-asserted source
Amin Tahoun via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Gut pathogens. (1)