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Epidemiology, Bioinformatics, Cardiovascular disease, Coronary heart disease, Causal inference, Mendelian randomization, Genome-wide association studies, Genetics, Longitudinal, Trajectory, Alcohol, Breast cancer, Oncology, Risk prediction, Prognosis
United Kingdom

Biography

I am an Epidemiologist based within the Precision Breast Cancer Institute, Department of Oncology at the University of Cambridge.

At present my work utilises next-generation sequencing data alongside bioinformatic approaches to obtain insights in the aetiology and prognosis of breast cancer. This includes applying techniques such as Mendelian randomization to prioritise therapeutic targets and inform clinical or public health decision making.

More widely, I have an interest in individual participant data meta-analysis, the use of electronic health records in medical research, the application and integration of various “-omic” technologies (e.g. metabolomics, proteomics, phenomics), machine learning and modelling of longitudinal data.

Activities

Professional activities (4)

Journal of Epidemiology and Community Health: London, GB

2022-11-05 to present | Associate Editor
Service
Source: Self-asserted source
Steven Bell

BMC Medicine: London, GB

2020-10-21 to present | Associate Editor
Service
Source: Self-asserted source
Steven Bell

University College London: London, London, GB

2016-02-06 to present | Honorary Senior Research Associate (Research Department of Epidemiology and Public Health)
Invited position
Source: Self-asserted source
Steven Bell

Kettil Bruun Society: Melbourne, AU

2011-04-14 | Ole-Jørgen Skog Award
Distinction
Source: Self-asserted source
Steven Bell

Funding (3)

Using Multi-Modal Data Integration Across Breast Cancer Molecular Subtypes to Develop Predictors of Treatment Response, Early Relapse, and Survival and to Explore Early Signals of Later Metastatic Recurrence

2023-09-01 to 2027-08-31 | Grant
Congressionally Directed Medical Research Programs (Frederick, US)
GRANT_NUMBER:

HT9425-23-1-0767

Source: Self-asserted source
Steven Bell via DimensionsWizard

Using genetics to better understand disease processes in cerebral small vessel disease and vascular cognitive impairment to improve treatment and prediction

2022-09 to 2026-09 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

RG/F/22/110052

Source: Self-asserted source
Steven Bell

Alcohol Harms: The relationship between alcohol consumption and cardiovascular risk - A life-course perspective

2015-01-01 to 2018-06-29 | Grant
Medical Research Council (London, GB)
GRANT_NUMBER: MR/M006638/1
Source: Self-asserted source
Steven Bell via DimensionsWizard

Works (50 of 92)

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Novel loci and biomedical consequences of iron homoeostasis variation

Communications Biology
2024-12-06 | Journal article
Contributors: Elias Allara; Steven Bell; Rebecca Smith; Spencer J. Keene; Dipender Gill; Liam Gaziano; Deisy Morselli Gysi; Feiyi Wang; Vinicius Tragante; Amy Mason et al.
Source: check_circle
Crossref

Health characteristics and health behaviours in male former contact sports participants: comparison with general population controls in a Finnish cohort study

Journal of Epidemiology and Community Health
2024-11-27 | Journal article
Contributors: G David Batty; Steven Bell; Urho M Kujala; Seppo J Sarna; Jaakko Kaprio
Source: check_circle
Crossref

Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility

Nature Communications
2024-09-04 | Journal article
Contributors: Shadi Basyuni; Laura Heskin; Andrea Degasperi; Daniella Black; Gene C. C. Koh; Lucia Chmelova; Giuseppe Rinaldi; Steven Bell; Louise Grybowicz; Greg Elgar et al.
Source: check_circle
Crossref

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction

Nature Genetics
2024-06 | Journal article
Contributors: Barbara Schormair; Chen Zhao; Steven Bell; Maria Didriksen; Muhammad S. Nawaz; Nathalie Schandra; Ambra Stefani; Birgit Högl; Yves Dauvilliers; Cornelius G. Bachmann et al.
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Crossref

Nucleus of fairness: epigenetic ageing, social determinants of health and the imperative for proactive preventive measures

Journal of Epidemiology and Community Health
2024-06 | Journal article
Contributors: Steven Bell
Source: check_circle
Crossref

Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic traits in liver steatosis and cirrhosis: a two-step Mendelian randomization study.

BMC medicine
2024-06-26 | Journal article
Contributors: Liang Y; Luo S; Bell S; Mo JMY; He B; Zhou Y; Bai X; Au Yeung SL
Source: Self-asserted source
Steven Bell
grade
Preferred source (of 2)‎

Apathy After Stroke

Neurology
2024-02-13 | Journal article
Contributors: Claudia Pallucca; Danuta M. Lisiecka-Ford; Lisa Wood; Azim Abul; Amy A. Jolly; Daniel J. Tozer; Steven Bell; Anne Forster; Robin G. Morris; Hugh S. Markus
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Crossref
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Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models

Cerebral Circulation - Cognition and Behavior
2023 | Journal article
Part of ISSN: 2666-2450
Contributors: Rui Li; Eric L. Harshfield; Steven Bell; Michael Burkhart; Anil M. Tuladhar; Saima Hilal; Daniel J. Tozer; Francesca M. Chappell; Stephen D.J. Makin; Jessica W. Lo et al.
Source: Self-asserted source
Steven Bell

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases

Stem Cell Reports
2023-12 | Journal article
Part of ISSN: 2213-6711
Contributors: Maha Al-Thani; Mary Goodwin-Trotman; Steven Bell; Krushangi Patel; Lauren K. Fleming; Catheline Vilain; Marc Abramowicz; Stuart M. Allan; Tao Wang; M. Zameel Cader et al.
Source: Self-asserted source
Steven Bell

Binge-pattern alcohol consumption and genetic risk as determinants of alcohol-related liver disease

Nature Communications
2023-12-14 | Journal article
Contributors: Chengyi Ding; Linda Ng Fat; Annie Britton; Pek Kei Im; Kuang Lin; Anya Topiwala; Liming Li; Zhengming Chen; Iona Y. Millwood; Steven Bell et al.
Source: check_circle
Crossref

Development and validation of a nomogram for predicting internal mammary sentinel node metastasis in breast cancer patients

European Journal of Surgical Oncology
2023-10 | Journal article
Contributors: Peng-Fei Qiu; Qing Lv; Wen-He Zhao; Yuan-Xi Huang; Shi-Guang Zhu; Hong Zhong; Guang-Lun Yang; Steven Bell; Li-Yang Wang; Ying-Ying Xu et al.
Source: check_circle
Crossref

The write algorithm: promoting responsible artificial intelligence usage and accountability in academic writing

BMC Medicine
2023-09-04 | Journal article
Contributors: Steven Bell
Source: check_circle
Crossref

A comprehensive evaluation of the longitudinal association between alcohol consumption and a measure of inflammation: Multiverse and vibration of effects analyses

Drug and Alcohol Dependence
2023-06 | Journal article
Contributors: Rachel Visontay; Louise Mewton; Matthew Sunderland; Steven Bell; Annie Britton; Bridie Osman; Hayley North; Nisha Mathew; Tim Slade
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Crossref

Association of gout with brain reserve and vulnerability to neurodegenerative disease

Nature Communications
2023-05-18 | Journal article
Contributors: Anya Topiwala; Kulveer Mankia; Steven Bell; Alastair Webb; Klaus P. Ebmeier; Isobel Howard; Chaoyue Wang; Fidel Alfaro-Almagro; Karla Miller; Stephen Burgess et al.
Source: check_circle
Crossref

Impact of a post‐donation hemoglobin testing strategy on efficiency and safety of whole blood donation in England: A modeling study

Transfusion
2023-03 | Journal article
Part of ISSN: 0041-1132
Part of ISSN: 1537-2995
Contributors: Lois Kim; Thomas Bolton; Michael J. Sweeting; Steven Bell; Sarah Fahle; Amy McMahon; Matthew Walker; Eamonn Ferguson; Gail Miflin; David J. Roberts et al.
Source: Self-asserted source
Steven Bell

Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease

NeuroImage: Clinical
2022 | Journal article
Part of ISSN: 2213-1582
Contributors: Marco Egle; Saima Hilal; Anil M Tuladhar; Lukas Pirpamer; Steven Bell; Edith Hofer; Marco Duering; James Wason; Robin G Morris; Martin Dichgans et al.
Source: Self-asserted source
Steven Bell via Crossref Metadata Search

Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke

JAMA Neurology
2022-12-01 | Journal article
Part of ISSN: 2168-6149
Contributors: Bernard P. H. Cho; Eric L. Harshfield; Maha Al-Thani; Daniel J. Tozer; Steven Bell; Hugh S. Markus
Source: Self-asserted source
Steven Bell

Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses

Circulation
2022-11-15 | Journal article
Contributors: Liam Gaziano; Luanluan Sun; Matthew Arnold; Steven Bell; Kelly Cho; Stephen K. Kaptoge; Rebecca J. Song; Stephen Burgess; Daniel C. Posner; Katja Mosconi et al.
Source: check_circle
Crossref

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke

Neurology
2022-10-18 | Journal article | Author
Part of ISSN: 0028-3878
Part of ISSN: 1526-632X
Contributors: Thomas Jaworek; Huichun Xu; Brady Gaynor; John Cole; Kristiina Rannikmae; Tara M. Stanne; Liisa Tomppo; Vida Abedi; Philippe Amouyel; Nicole D. Armstrong et al.
Source: Self-asserted source
Steven Bell

Genome-wide association study of the human brain functional connectome reveals strong vascular component underlying global network efficiency

Scientific Reports
2022-09-02 | Journal article
Part of ISSN: 2045-2322
Contributors: Steven Bell; Daniel J. Tozer; Hugh S. Markus
Source: Self-asserted source
Steven Bell via Crossref Metadata Search

Association of NOTCH3 Variant Position With Stroke Onset and Other Clinical Features Among Patients With CADASIL

Neurology
2022-08-02 | Journal article
Contributors: Bernard P.H. Cho; Amy A. Jolly; Stefania Nannoni; Daniel Tozer; Steven Bell; Hugh S. Markus
Source: check_circle
Crossref

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses

PLOS Medicine
2022-07-14 | Journal article
Contributors: Anya Topiwala; Perminder Singh Sachdev; Chaoyue Wang; Klaus P. Ebmeier; Stephen Burgess; Steven Bell; Daniel F. Levey; Hang Zhou; Celeste McCracken; Adriana Roca-Fernández et al.
Source: check_circle
Crossref

Mortality among rough sleepers, squatters, residents of homeless shelters or hotels and sofa-surfers: a pooled analysis of UK birth cohorts

International Journal of Epidemiology
2022-06-13 | Journal article
Part of ISSN: 0300-5771
Part of ISSN: 1464-3685
Contributors: James White; Meg Fluharty; Rosa de Groot; Steven Bell; G David Batty
Source: Self-asserted source
Steven Bell

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

Nature
2022-04-06 | Journal article
Part of ISSN: 0028-0836
Contributors: Caroline Junqueira; Ângela Crespo; Shahin Ranjbar; Luna B. de Lacerda; Mercedes Lewandrowski; Jacob Ingber; Blair Parry; Sagi Ravid; Sarah Clark; Marie Rose Schrimpf et al.
Source: Self-asserted source
Steven Bell via Crossref Metadata Search

Disulfiram use is associated with lower risk of COVID-19: A retrospective cohort study

PLOS ONE
2021-10-28 | Journal article
Contributors: Nathanael Fillmore; Mohd Adnan; Steven Bell; Ciyue Shen; Vinh Nguyen; Jennifer La; Maureen Dubreuil; Judith Strymish; Mary Brophy; Gautam Mehta et al.
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Crossref
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Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies

The Lancet Neurology
2021-05 | Journal article
Part of ISSN: 1474-4422
Contributors: Matthew Traylor; Elodie Persyn; Liisa Tomppo; Sofia Klasson; Vida Abedi; Mark K Bakker; Nuria Torres; Linxin Li; Steven Bell; Loes Rutten-Jacobs et al.
Source: Self-asserted source
Steven Bell

Comparison of four methods to measure haemoglobin concentrations in whole blood donors (COMPARE): A diagnostic accuracy study

Transfusion Medicine
2021-04 | Journal article
Contributors: Steven Bell; Michael Sweeting; Anna Ramond; Ryan Chung; Stephen Kaptoge; Matthew Walker; Thomas Bolton; Jennifer Sambrook; Carmel Moore; Amy McMahon et al.
Source: check_circle
Crossref

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

Communications Biology
2021-02-03 | Journal article
Contributors: Steven Bell; Andreas S. Rigas; Magnus K. Magnusson; Egil Ferkingstad; Elias Allara; Gyda Bjornsdottir; Anna Ramond; Erik Sørensen; Gisli H. Halldorsson; Dirk S. Paul et al.
Source: check_circle
Crossref

Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses

PLOS Medicine
2021-01-14 | Journal article
Contributors: Luanluan Sun; George Hindy; Lisa Pennells; Stephen Kaptoge; Christopher P. Nelson; Scott C. Ritchie; Gad Abraham; Matthew Arnold; Steven Bell; Thomas Bolton et al.
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Crossref

NOTCH3 variants are common in the general population and associated with stroke and vascular dementia: an analysis of 200,000 participants

2020-12-14 | Other
Contributors: Bernard PH Cho; Stefania Nannoni; Eric L Harshfield; Daniel J Tozer; Stefan Gräf; Steven Bell; Hugh S Markus
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Crossref

Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study

Atherosclerosis
2020-11 | Journal article
Contributors: Steven Bell; Joel T. Gibson; Eric L. Harshfield; Hugh S. Markus
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Crossref

Large genome-wide association study identifies three novel risk variants for restless legs syndrome

Communications Biology
2020-11-25 | Journal article
Contributors: Maria Didriksen; Muhammad Sulaman Nawaz; Joseph Dowsett; Steven Bell; Christian Erikstrup; Ole B. Pedersen; Erik Sørensen; Poul J. Jennum; Kristoffer S. Burgdorf; Brendan Burchell et al.
Source: check_circle
Crossref

Stroke in COVID-19: A systematic review and meta-analysis

International Journal of Stroke
2020-11-11 | Journal article
Part of ISSN: 1747-4930
Contributors: Stefania Nannoni; Rosa de Groot; Steven Bell; Hugh S Markus
Source: Self-asserted source
Steven Bell via Crossref Metadata Search

A life‐time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study

Addiction
2020-10 | Journal article
Contributors: Linda Ng Fat; Steven Bell; Annie Britton
Source: check_circle
Crossref

Sustained heavy drinking over 25 years is associated with increased N-terminal-pro-B-type natriuretic peptides in early old age: Population-based cohort study

Drug and Alcohol Dependence
2020-07 | Journal article
Part of ISSN: 0376-8716
Source: Self-asserted source
Steven Bell

Association of illicit drug use in adolescence with socioeconomic and criminal justice outcomes in adulthood: prospective findings from a UK national birth cohort

Journal of Epidemiology and Community Health
2020-05-04 | Journal article
Part of ISSN: 0143-005X
Part of ISSN: 1470-2738
Source: Self-asserted source
Steven Bell

Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta‐analysis consisting 2.8 million adults with 57 294 cases of dementia

Obesity Reviews
2020-04 | Journal article
Part of ISSN: 1467-7881
Part of ISSN: 1467-789X
Source: Self-asserted source
Steven Bell

Change in device-measured physical activity assessed in childhood and adolescence in relation to depressive symptoms: a general population-based cohort study

Journal of Epidemiology and Community Health
2020-04 | Journal article
Part of ISSN: 0143-005X
Part of ISSN: 1470-2738
Source: Self-asserted source
Steven Bell

Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis

BMJ
2020-02-12 | Journal article
Part of ISSN: 1756-1833
Source: Self-asserted source
Steven Bell

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

Nature Communications
2020-02-12 | Journal article
Source: Self-asserted source
Steven Bell
grade
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Does the social context of early alcohol use affect alcohol-related harms in adulthood? Findings from a national birth cohort

Preventive Medicine
2020-01 | Journal article
Part of ISSN: 0091-7435
Source: Self-asserted source
Steven Bell

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes

Circulation: Genomic and Precision Medicine
2019-12 | Journal article
Part of ISSN: 2574-8300
Part of ISSN: 2574-8300
Source: Self-asserted source
Steven Bell

Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

Nature Communications
2019-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Steven Bell
grade
Preferred source (of 2)‎

Out‐of‐home care in childhood and biomedical risk factors in middle‐age: National birth cohort study

American Journal of Human Biology
2019-11-05 | Journal article
Part of ISSN: 1042-0533
Part of ISSN: 1520-6300
Source: Self-asserted source
Steven Bell
grade
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World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions

The Lancet Global Health
2019-10 | Journal article
Part of ISSN: 2214-109X
Source: Self-asserted source
Steven Bell

Comparison of risk factors for coronary heart disease morbidity versus mortality

European Journal of Preventive Cardiology
2019-10-16 | Journal article
Part of ISSN: 2047-4873
Part of ISSN: 2047-4881
Source: Self-asserted source
Steven Bell
grade
Preferred source (of 2)‎

Assessment of Relative Utility of Underlying vs Contributory Causes of Death

JAMA Network Open
2019-07-31 | Journal article
Part of ISSN: 2574-3805
Source: Self-asserted source
Steven Bell

Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses.

BMJ (Clinical research ed.)
2019-03-26 | Journal article
Source: Self-asserted source
Steven Bell

Cardiovascular Risk Factors Associated With Venous Thromboembolism.

JAMA cardiology
2019-02-01 | Journal article
Source: Self-asserted source
Steven Bell

Testing Differential Associations Between Smoking and Chronic Disease Across Socioeconomic Groups: Pooled Data From 15 Prospective Studies.

Epidemiology (Cambridge, Mass.)
2019-01-01 | Journal article
Source: Self-asserted source
Steven Bell
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