Personal information

Biography

Jeffrey Cummings, MD, ScD, is the Joy Chambers-Grundy Professor of Brain Science, Director of the Chambers-Gundy Center for Transformative Neuroscience, Co-Director of the Pam Quirk Brain Health and Biomarker Laboratory, Department of Brain Health, School of Integrated Health Sciences, University of Nevada Las Vegas (UNLV). Dr. Cummings is globally recognized for his contributions to Alzheimer’s research, drug development, and clinical trials. He has been recognized for his research and leadership contributions in the field of Alzheimer’s disease through many awards including the Ronald and Nancy Reagan Research Award of the national Alzheimer’s Association (2008), Lifetime Achievement Award of the Society for Behavioral and Cognitive Neurology (2017), Distinguished Scientist Award of the American Association of Geriatric Psychiatry (2010), Bengt Winblad Lifetime Achievement Award from the national Alzheimer’s Association (2019), and the Alzheimer’s Drug Discovery Foundation’s Melvin R. Goodes Prize. He was featured in the Gentleman’s Quarterly (June 2009) as a “Rock Star of Science™.” Dr. Cummings completed Neurology residency and a Fellowship in Behavioral Neurology at Boston University, followed by a Research Fellowship in Neuropathology and Neuropsychiatry at the National Hospital for Nervous Diseases, Queen Square, London. Dr. Cummings was formerly Director of the Mary S. Easton Center for Alzheimer’s Disease Research at UCLA, and Director of the Cleveland Clinic Lou Ruvo Center for Brain Health. Dr. Cummings’ interests embrace clinical trials, developing new therapies for brain diseases, and the interface of neuroscience and society. He has authored or edited 43 books and published over 800 peer-reviewed papers.

Activities

Employment (2)

University of Nevada Las Vegas: Las Vegas, Nevada, US

2019-01-01 to present | Joy Chambers-Grundy Professor of Brain Science; Director, Chambers-Gundy Center for Transformative Neuroscience; Co-Director, Pam Quirk Brain Health and Biomarker Laboratory (School of Integrated Health Sciences / Department of Brain Health)
Employment
Source: Self-asserted source
Jeffrey Cummings

Cleveland Clinic Lou Ruvo Center for Brain Health: Las Vegas, Nevada, US

2010-07-01 to 2020-12-31 | Founding Director
Employment
Source: Self-asserted source
Jeffrey Cummings

Education and qualifications (3)

University of Wyoming: Laramie, WY, US

ScD(HC)
Education
Source: Self-asserted source
Jeffrey Cummings

University of Wyoming: Laramie, WY, US

Bachelor of Science
Education
Source: Self-asserted source
Jeffrey Cummings

University of Washington School of Medicine: Seattle, WA, US

MD
Education
Source: Self-asserted source
Jeffrey Cummings

Professional activities (3)

Alzheimer's Drug Discovery Foundation: NY, NY, US

2019-09-13 | The Melvin R. Goodes Prize
Distinction
Source: Self-asserted source
Jeffrey Cummings

International Psychogeriatric Association: WI, WI, US

2019-08-31 | Distinguished Service Award
Distinction
Source: Self-asserted source
Jeffrey Cummings

Alzheimer's Association: Chicago, Illinois, US

2018-07-24 | Bengt Winblad Lifetime Achievment Award
Distinction
Source: Self-asserted source
Jeffrey Cummings

Funding (16)

Global Alzheimer's Platform Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease

2017-05-01 to 2023-04-30 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: R01AG053798
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

A phase 2 study of intranasal oxytocin for Frontotemporal Dementia

2016-07-01 to 2020-06-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
GRANT_NUMBER:

9ad4b72a5839fd4ed4f120dd56307aa4

Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors

2015-12-15 to 2022-11-30 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
GRANT_NUMBER: U01NS093334
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

COBRE GRANT

2015-09-01 to 2020-05-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: P20GM109025
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Rasagiline Rescue in Alzheimer's Disease Clinical Trial (Follow-On)

2014-12-01 to 2016-02-15 | Grant
Alzheimer's Drug Discovery Foundation (New York, US)
GRANT_NUMBER:

addf1e86dc54424ad0350280280824462195

Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Rasagiline Rescue in Alzheimer's Disease Clinical Trial (R2 Trial)

2014-04-11 to 2016-04-11 | Grant
Alzheimer's Drug Discovery Foundation (New York, US)
GRANT_NUMBER:

addf3ea72032947e08966773d77acfed4c33

Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Clinical Trials in Frontotemporal Degeneration and Related Disorders

2011-11-01 to 2012-10-31 | Grant
Alzheimer's Drug Discovery Foundation (New York, US)
GRANT_NUMBER:

addf3007d299afba0b1c5c759cfe86aff9bc

Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Dementia and Disability in Thai Elderly

2003-07-15 to 2007-06-30 | Grant
Fogarty International Center (Bethesda, US)
GRANT_NUMBER: R03TW006426
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Multicenter Analysis of Hippocampal Morphology in MCI

2000-10-16 to 2002-11-30 | Grant
Alzheimer's Drug Discovery Foundation (New York, US)
GRANT_NUMBER:

addfccca89526adca61def7c4d738ecaee28

Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

UCLA Alzheimer's Disease Research Center

1999-04-05 to 2016-03-31 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: P50AG016570
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Computational Anatomy and Multidimensional Modeling

1998-09-30 to 2012-07-31 | Grant
National Center for Advancing Translational Sciences (Rockville, US)
GRANT_NUMBER: P41RR013642
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

LOS ANGELES AREA ALZHEIMER'S OUTREACH PROGRAM (LAAAOP)

1992-09-30 to 1998-06-30 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: R25AG011325
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

UCLA ALZHEIMERS DISEASE CENTER

1991-09-30 to 1999-03-31 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: P30AG010123
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

DEMENTIA AND BEHAVIORAL NEUROLOGY: RESEARCH FELLOWSHIP

1988-09-01 to 2004-04-30 | Grant
National Institute on Aging (Baltimore, US)
GRANT_NUMBER: T32AG000172
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

General Clinical Research Center

1978-12-01 to 2011-05-31 | Grant
National Center for Advancing Translational Sciences (Rockville, US)
GRANT_NUMBER: M01RR000865
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

CLINICAL RESEARCH CENTER FOR THE STUDY OF SCHIZOPHRENIA

1977-09-29 to 1995-11-30 | Grant
National Institute of Mental Health (Bethesda, US)
GRANT_NUMBER: P50MH030911
Source: Self-asserted source
Jeffrey Cummings via DimensionsWizard

Works (20)

Drug repurposing for Alzheimer’s disease and other neurodegenerative disorders

Nature Communications
2025-02-19 | Journal article
Contributors: Jeffrey L. Cummings; Yadi Zhou; Alexandra Van Stone; Davis Cammann; Reina Tonegawa-Kuji; Jorge Fonseca; Feixiong Cheng
Source: check_circle
Crossref

Alzheimer’s Disease: Combination Therapies and Clinical Trials for Combination Therapy Development

CNS Drugs
2024-08 | Journal article
Contributors: Jeffrey L. Cummings; Amanda M. Leisgang Osse; Jefferson W. Kinney; Davis Cammann; Jingchun Chen
Source: check_circle
Crossref

Rarer dementias, limited options, and unaddressed needs

International Psychogeriatrics
2024-06 | Journal article
Contributors: Jeffrey Cummings
Source: check_circle
Crossref

Agitation in cognitive disorders: Progress in the International Psychogeriatric Association consensus clinical and research definition

International Psychogeriatrics
2024-04 | Journal article
Contributors: Mary Sano; Jeffrey Cummings; Stefanie Auer; Sverre Bergh; Corinne E. Fischer; Debby Gerritsen; George Grossberg; Zahinoor Ismail; Krista Lanctôt; Maria I. Lapid et al.
Source: check_circle
Crossref

Reduction and prevention of agitation in persons with neurocognitive disorders: an international psychogeriatric association consensus algorithm

International Psychogeriatrics
2024-04 | Journal article
Contributors: Jeffrey Cummings; Mary Sano; Stefanie Auer; Sverre Bergh; Corinne E. Fischer; Debby Gerritsen; George Grossberg; Zahinoor Ismail; Krista Lanctôt; Maria I. Lapid et al.
Source: check_circle
Crossref

Scenarios for the long-term efficacy of amyloid-targeting therapies in the context of the natural history of Alzheimer’s disease

2024-02-27 | Preprint
Contributors: Lars Lau Raket; Jeffrey Cummings; Alexis Moscoso; Nicolas Villain; Michael Schöll
Source: check_circle
Crossref

Anti-Amyloid Monoclonal Antibodies for the Treatment of Alzheimer’s Disease

BioDrugs
2024-01 | Journal article
Contributors: Jeffrey Cummings; Amanda M. Leisgang Osse; Davis Cammann; Jayde Powell; Jingchun Chen
Source: check_circle
Crossref

Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification

Drugs
2023-10 | Journal article
Contributors: Jeffrey L. Cummings; Amanda M. Leisgang Osse; Jefferson W. Kinney
Source: check_circle
Crossref

Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics

Drugs
2023-05 | Journal article
Contributors: Jeffrey Cummings
Source: check_circle
Crossref

Distinguishing apathy from depression: A review differentiating the behavioral, neuroanatomic, and treatment‐related aspects of apathy from depression in neurocognitive disorders

International Journal of Geriatric Psychiatry
2023-02 | Journal article
Contributors: Krista L. Lanctôt; Zahinoor Ismail; Kritleen K. Bawa; Jeffrey L. Cummings; Masud Husain; Moyra E. Mortby; Philippe Robert
Source: check_circle
Crossref

Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders

Biomolecules
2023-02-07 | Journal article
Contributors: Ramakrishna Nirogi; Pradeep Jayarajan; Anil Shinde; Abdul Rasheed Mohammed; Venkata Ramalingayya Grandhi; Vijay Benade; Vinod Kumar Goyal; Renny Abraham; Venkat Jasti; Jeffrey Cummings
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Diabetes: Risk factor and translational therapeutic implications for Alzheimer's disease

European Journal of Neuroscience
2022-11 | Journal article
Contributors: Jeffrey Cummings; Andrew Ortiz; Janelle Castellino; Jefferson Kinney
Source: check_circle
Crossref

Pimavanserin for the Treatment of Alzheimer’s Disease Psychosis: An Evaluation of the Clinical Importance of Efficacy Results

2022-08-12 | Preprint
Contributors: Clive Ballard; Jeffrey Cummings; Pierre N Tariot; Sanjeev Pathak; Bruce Coate; Srdjan Stankovic
Source: check_circle
Crossref

Biomarkers for Alzheimer’s Disease: Context of Use, Qualification, and Roadmap for Clinical Implementation

Medicina
2022-07-19 | Journal article
Contributors: Jeffrey Cummings; Jefferson Kinney
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Aducanumab produced a clinically meaningful benefit in association with amyloid lowering

Alzheimer's Research & Therapy
2021-12 | Journal article
Contributors: Jeffrey Cummings; Paul Aisen; Cynthia Lemere; Alireza Atri; Marwan Sabbagh; Stephen Salloway
Source: check_circle
Crossref

New approaches to symptomatic treatments for Alzheimer’s disease

Molecular Neurodegeneration
2021-01-13 | Journal article
Contributors: Jeffrey Cummings
Source: check_circle
Crossref

The Truth behind the Zeros: A New Approach to Principal Component Analysis of the Neuropsychiatric Inventory

Multivariate Behavioral Research
2021-01-02 | Journal article
Contributors: Kristoffer H. Hellton; Jeffrey Cummings; Audun Osland Vik-Mo; Jan Erik Nordrehaug; Dag Aarsland; Geir Selbaek; Lasse Melvaer Giil
Source: check_circle
Crossref

Repurposed agents in the Alzheimer’s disease drug development pipeline

Alzheimer's Research & Therapy
2020-08-17 | Journal article
Contributors: Justin Bauzon; Garam Lee; Jeffrey Cummings
Source: check_circle
Crossref

Awareness of Psychiatric Symptoms in a Mixed Clinical Sample of Older Adults

Journal of Geriatric Psychiatry and Neurology
2020-05 | Journal article
Contributors: Hannah E. Brunet; Jeffrey L. Cummings; Sarah J. Banks; Justin B. Miller
Source: check_circle
Crossref

The Neuropsychiatric Inventory: Development and Applications

Journal of Geriatric Psychiatry and Neurology
2020-03 | Journal article
Contributors: Jeffrey Cummings
Source: check_circle
Crossref

Peer review (4 reviews for 2 publications/grants)

Review activity for Alzheimer's research & therapy (3)
Review activity for JPAD. (1)